The network for 'establishment of protein localization to endoplasmic reticulum' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

establishment of protein localization to endoplasmic reticulum

The directed movement of a protein to a specific location in the endoplasmic reticulum.

Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
SEC63 Sec63p 1.000
SEC62 Sec62p 0.999
SPC2 Spc2p 0.987
SPC1 Spc1p 0.986
SGT2 Sgt2p 0.985
KAR2 Kar2p 0.980
SRP72 Srp72p 0.976
SBH1 Sbh1p 0.976
SRP14 Srp14p 0.974
SRP54 Srp54p 0.957
SRP68 Srp68p 0.946
SEC65 Sec65p 0.943
SRP21 Srp21p 0.942
SEC66 Sec66p 0.932
SEC11 Sec11p 0.862
SEC61 Sec61p 0.743
GET3 Get3p 0.724
SIS1 Sis1p 0.685
YDJ1 Ydj1p 0.625
SSS1 Sss1p 0.615
SSH1 Ssh1p 0.607
GET1 Get1p 0.603
MDY2 Mdy2p 0.601
JEM1 Jem1p 0.475
SIL1 Sil1p 0.465
GET4 Get4p 0.347
LHS1 Lhs1p 0.237
SCJ1 Scj1p 0.226
EGD2 Egd2p 0.219
SEC72 Sec72p 0.214
SPC3 Spc3p 0.191
EGD1 Egd1p 0.180
STI1 Sti1p 0.173
PRP45 Prp45p 0.164
BFR1 Bfr1p 0.157
PGA2 Pga2p 0.153
ERD2 Erd2p 0.149
CPR6 Cpr6p 0.147
SSE1 Sse1p 0.129
ERP2 Erp2p 0.118
ERV25 Erv25p 0.109
OST4 Ost4p 0.097
UBC4 Ubc4p 0.095
LCL2 Lcl2p 0.095
YRB1 Yrb1p 0.085
RPS29B Rps29bp 0.082
WBP1 Wbp1p 0.080
YLR126C hypothetical protein 0.077
YPT32 Ypt32p 0.075
CUE4 Cue4p 0.072
CAF130 Caf130p 0.069
ERJ5 Erj5p 0.068
ERO1 Ero1p 0.065
EMC4 Emc4p 0.061
SNU13 Snu13p 0.059
NOP58 Nop58p 0.057
PRS2 Prs2p 0.055
SED5 Sed5p 0.052
HTA2 Hta2p 0.051
STE24 Ste24p 0.048
RPL15B Rpl15bp 0.048
GND1 Gnd1p 0.047
CTR9 Ctr9p 0.046
RPI1 Rpi1p 0.045
BTT1 Btt1p 0.044
YLR264C-A hypothetical protein 0.044
FAS2 Fas2p 0.042
HLJ1 Hlj1p 0.041
OST2 Ost2p 0.039
SRD1 Srd1p 0.039
ERG25 Erg25p 0.038
LEU2 Leu2p 0.037
YDL085C-A hypothetical protein 0.037
YKL063C hypothetical protein 0.036
YOL038C-A hypothetical protein 0.036
CUP1-1 Cup1-1p 0.035
YBR085C-A hypothetical protein 0.034
SEC2 Sec2p 0.033
GYL1 Gyl1p 0.033
ARG8 Arg8p 0.033
YLR162W hypothetical protein 0.033
TAD2 Tad2p 0.032
NUP82 Nup82p 0.032
ALT1 Alt1p 0.032
ESF1 Esf1p 0.032
TSC3 Tsc3p 0.031
SAR1 Sar1p 0.031
DSS4 Dss4p 0.031
VMA11 Vma11p 0.031
ENO2 Eno2p 0.030
EMC2 Emc2p 0.030
HLR1 Hlr1p 0.030
LIF1 Lif1p 0.029
CAB4 Cab4p 0.029
ERV2 Erv2p 0.028
ADD66 Add66p 0.028
OPT2 Opt2p 0.028
CRP1 Crp1p 0.028
MER1 Mer1p 0.028
CLB3 Clb3p 0.027
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
HSPA1A heat shock 70kDa protein 1A 0.396
HSPA1B heat shock 70kDa protein 1B 0.371
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.246
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.150
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.139
CANX calnexin 0.086
BAG1 BCL2-associated athanogene 0.081
BAG3 BCL2-associated athanogene 3 0.053
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.037
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.037
BAG6 BCL2-associated athanogene 6 0.023
HSPH1 heat shock 105kDa/110kDa protein 1 0.020
PPIB peptidylprolyl isomerase B (cyclophilin B) 0.017
PPP5C protein phosphatase 5, catalytic subunit 0.015
RABIF RAB interacting factor 0.015
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.014
BAG2 BCL2-associated athanogene 2 0.014
RPL36AL ribosomal protein L36a-like 0.013
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta 0.011
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.011
SSR1 signal sequence receptor, alpha 0.011
ATF7IP activating transcription factor 7 interacting protein 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Iqcb1 IQ calmodulin-binding motif containing 1 0.155
Pdia6 protein disulfide isomerase associated 6 0.153
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.091
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.081
Hsph1 heat shock 105kDa/110kDa protein 1 0.067
Hspa5 heat shock protein 5 0.063
Dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.058
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.044
Rpgrip1l Rpgrip1-like 0.043
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 0.035
Manf mesencephalic astrocyte-derived neurotrophic factor 0.034
Creld2 cysteine-rich with EGF-like domains 2 0.033
Nphp1 nephronophthisis 1 (juvenile) homolog (human) 0.025
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.025
Calu calumenin 0.023
Ttc3 tetratricopeptide repeat domain 3 0.023
Invs inversin 0.021
Hspd1 heat shock protein 1 (chaperonin) 0.021
Ahi1 Abelson helper integration site 1 0.020
Scn5a sodium channel, voltage-gated, type V, alpha 0.019
Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.019
Cul3 cullin 3 0.019
Dnaja1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.019
Chordc1 cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1 0.018
Crk v-crk sarcoma virus CT10 oncogene homolog (avian) 0.018
D730040F13Rik RIKEN cDNA D730040F13 gene 0.018
Clasp1 CLIP associating protein 1 0.017
Kpna1 karyopherin (importin) alpha 1 0.016
Gja1 gap junction protein, alpha 1 0.016
Rrbp1 ribosome binding protein 1 0.016
Kpna3 karyopherin (importin) alpha 3 0.015
Scn1a sodium channel, voltage-gated, type I, alpha 0.015
Ntf3 neurotrophin 3 0.014
Hspa9 heat shock protein 9 0.014
Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 0.014
Pex13 peroxisomal biogenesis factor 13 0.013
Ssr3 signal sequence receptor, gamma 0.013
Spnb2 spectrin beta 2 0.013
Pdia3 protein disulfide isomerase associated 3 0.013
Csde1 cold shock domain containing E1, RNA binding 0.013
Sdf2l1 stromal cell-derived factor 2-like 1 0.013
Hyou1 hypoxia up-regulated 1 0.012
Arih1 ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila) 0.012
Clasp2 CLIP associating protein 2 0.012
Mks1 Meckel syndrome, type 1 0.012
Surf4 surfeit gene 4 0.012
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.012
6330409N04Rik RIKEN cDNA 6330409N04 gene 0.011
Spcs2 signal peptidase complex subunit 2 homolog (S. cerevisiae) 0.011
Lrrc59 leucine rich repeat containing 59 0.011
Cops2 COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana) 0.011
Bdnf brain derived neurotrophic factor 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism