The network for 'trna wobble uridine modification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

trna wobble uridine modification

The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.

Danio rerio
Name Description Probability Func Analog Organism
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein 1.000
ELP2 elongation protein 2 homolog (S. cerevisiae) 0.980
ELP3 elongation protein 3 homolog (S. cerevisiae) 0.943
FAM96B family with sequence similarity 96, member B 0.667
ELP4 elongation protein 4 homolog (S. cerevisiae) 0.609
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.123
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.091
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.083
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 0.057
CSNK1E casein kinase 1, epsilon 0.055
ANKRD28 ankyrin repeat domain 28 0.051
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.048
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A 0.047
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.034
OCLN occludin 0.026
HTT huntingtin 0.026
ASCC2 activating signal cointegrator 1 complex subunit 2 0.020
MYST2 MYST histone acetyltransferase 2 0.020
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon 0.019
MCC mutated in colorectal cancers 0.016
NIPSNAP3A nipsnap homolog 3A (C. elegans) 0.015
NTHL1 nth endonuclease III-like 1 (E. coli) 0.014
SNAPIN SNAP-associated protein 0.014
MOBKL1A MOB1, Mps One Binder kinase activator-like 1A (yeast) 0.013
DVL2 dishevelled, dsh homolog 2 (Drosophila) 0.012
KPNA1 karyopherin alpha 1 (importin alpha 5) 0.011
HEATR2 HEAT repeat containing 2 0.011
CSNK1A1 casein kinase 1, alpha 1 0.011
FAM110A family with sequence similarity 110, member A 0.010
MAPK8 mitogen-activated protein kinase 8 0.010
FAM110C family with sequence similarity 110, member C 0.010
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Mus musculus
Name Description Probability Func Analog Organism
Mrps18b mitochondrial ribosomal protein S18B 0.514
Ddx41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 0.292
Eftud2 elongation factor Tu GTP binding domain containing 2 0.183
Vps25 vacuolar protein sorting 25 (yeast) 0.167
Per1 period homolog 1 (Drosophila) 0.150
Ddx56 DEAD (Asp-Glu-Ala-Asp) box polypeptide 56 0.145
Nono non-POU-domain-containing, octamer binding protein 0.137
Noc4l nucleolar complex associated 4 homolog (S. cerevisiae) 0.136
Drg1 developmentally regulated GTP binding protein 1 0.127
Anapc2 anaphase promoting complex subunit 2 0.117
Sox4 SRY-box containing gene 4 0.095
Cpsf3 cleavage and polyadenylation specificity factor 3 0.091
Nudt16l1 nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1 0.090
Prpf6 PRP6 pre-mRNA splicing factor 6 homolog (yeast) 0.085
Ube2g1 ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, C. elegans) 0.082
Parn poly(A)-specific ribonuclease (deadenylation nuclease) 0.076
Zfp740 zinc finger protein 740 0.070
Asna1 arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) 0.067
Mrps23 mitochondrial ribosomal protein S23 0.065
Dus1l dihydrouridine synthase 1-like (S. cerevisiae) 0.064
Glg1 golgi apparatus protein 1 0.063
Jagn1 jagunal homolog 1 (Drosophila) 0.057
Anapc4 anaphase promoting complex subunit 4 0.056
Rrp1 ribosomal RNA processing 1 homolog (S. cerevisiae) 0.052
Ppp1r7 protein phosphatase 1, regulatory (inhibitor) subunit 7 0.050
0610010K14Rik RIKEN cDNA 0610010K14 gene 0.048
Ppp1ca protein phosphatase 1, catalytic subunit, alpha isoform 0.048
Wdr74 WD repeat domain 74 0.047
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.046
Impad1 inositol monophosphatase domain containing 1 0.046
Pnkp polynucleotide kinase 3'- phosphatase 0.045
Hnrnpr heterogeneous nuclear ribonucleoprotein R 0.045
Drg2 developmentally regulated GTP binding protein 2 0.044
Snap47 synaptosomal-associated protein, 47 0.044
Hif1a hypoxia inducible factor 1, alpha subunit 0.044
Sec13 SEC13 homolog (S. cerevisiae) 0.044
Dhx30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.043
2610027L16Rik RIKEN cDNA 2610027L16 gene 0.043
Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 0.042
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.042
Cdk4 cyclin-dependent kinase 4 0.041
Atpaf2 ATP synthase mitochondrial F1 complex assembly factor 2 0.041
Parl presenilin associated, rhomboid-like 0.039
Vps16 vacuolar protein sorting 16 (yeast) 0.037
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.037
Ssr2 signal sequence receptor, beta 0.037
Elp2 elongation protein 2 homolog (S. cerevisiae) 0.037
Commd4 COMM domain containing 4 0.037
Elp3 elongation protein 3 homolog (S. cerevisiae) 0.036
Mrpl37 mitochondrial ribosomal protein L37 0.036
Psmc4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.035
Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.035
Vars valyl-tRNA synthetase 0.034
Fbxw11 F-box and WD-40 domain protein 11 0.034
D10Wsu52e DNA segment, Chr 10, Wayne State University 52, expressed 0.031
Eif6 eukaryotic translation initiation factor 6 0.030
Lsg1 large subunit GTPase 1 homolog (S. cerevisiae) 0.030
Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 0.029
Triap1 TP53 regulated inhibitor of apoptosis 1 0.029
Zranb2 zinc finger, RAN-binding domain containing 2 0.029
Imp4 IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast) 0.029
Th1l TH1-like homolog (Drosophila) 0.028
Usp22 ubiquitin specific peptidase 22 0.028
Ttc3 tetratricopeptide repeat domain 3 0.028
Pin1 protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 0.026
Gart phosphoribosylglycinamide formyltransferase 0.026
Gsk3b glycogen synthase kinase 3 beta 0.026
Gtf2h4 general transcription factor II H, polypeptide 4 0.026
Fam192a family with sequence similarity 192, member A 0.026
2410001C21Rik RIKEN cDNA 2410001C21 gene 0.026
Ppp4c protein phosphatase 4, catalytic subunit 0.026
Apex1 apurinic/apyrimidinic endonuclease 1 0.025
Brd4 bromodomain containing 4 0.025
Ctnnbl1 catenin, beta like 1 0.024
Sox11 SRY-box containing gene 11 0.024
Prpf31 PRP31 pre-mRNA processing factor 31 homolog (yeast) 0.024
Mcm3ap minichromosome maintenance deficient 3 (S. cerevisiae) associated protein 0.024
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.024
Ddx39b DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.024
Mlh1 mutL homolog 1 (E. coli) 0.023
Arpc4 actin related protein 2/3 complex, subunit 4 0.023
Gins4 GINS complex subunit 4 (Sld5 homolog) 0.023
Eif3b eukaryotic translation initiation factor 3, subunit B 0.023
Ptcd2 pentatricopeptide repeat domain 2 0.023
Pqbp1 polyglutamine binding protein 1 0.022
Lrrc59 leucine rich repeat containing 59 0.022
Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 0.022
Sept7 septin 7 0.022
Hnrnpk heterogeneous nuclear ribonucleoprotein K 0.021
Ptp4a2 protein tyrosine phosphatase 4a2 0.021
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.021
Polr3a polymerase (RNA) III (DNA directed) polypeptide A 0.021
Eif2b1 eukaryotic translation initiation factor 2B, subunit 1 (alpha) 0.021
C80913 expressed sequence C80913 0.021
Thoc3 THO complex 3 0.021
Ngrn neugrin, neurite outgrowth associated 0.020
Stx6 syntaxin 6 0.020
2310011J03Rik RIKEN cDNA 2310011J03 gene 0.020
Spag7 sperm associated antigen 7 0.020
Lsm4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.020
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ELP6 Elp6p 0.999
ELP4 Elp4p 0.999
NCS6 Ncs6p 0.998
ELP3 Elp3p 0.997
IKI3 Iki3p 0.996
IKI1 Iki1p 0.991
KTI11 Kti11p 0.972
UBA4 Uba4p 0.856
KTI12 Kti12p 0.852
NCS2 Ncs2p 0.803
URM1 Urm1p 0.747
ELP2 Elp2p 0.683
YHR122W hypothetical protein 0.674
HRR25 Hrr25p 0.390
NAR1 Nar1p 0.343
DRE2 Dre2p 0.270
SLM3 Slm3p 0.215
SIT4 Sit4p 0.202
NFS1 Nfs1p 0.171
MEX67 Mex67p 0.132
SUA5 Sua5p 0.113
SAK1 Sak1p 0.108
PRS2 Prs2p 0.107
YHR003C hypothetical protein 0.093
ISD11 Isd11p 0.090
THG1 Thg1p 0.075
PUS1 Pus1p 0.073
ABP140 Abp140p 0.072
TRM9 Trm9p 0.063
NUP82 Nup82p 0.061
SRD1 Srd1p 0.056
ATS1 Ats1p 0.054
NBA1 Nba1p 0.054
MER1 Mer1p 0.054
LIP5 Lip5p 0.052
ARG8 Arg8p 0.051
GLT1 Glt1p 0.049
CFD1 Cfd1p 0.047
SFA1 Sfa1p 0.046
SKS1 Sks1p 0.045
TYW1 Tyw1p 0.042
ADH2 Adh2p 0.040
ARP10 Arp10p 0.040
TUM1 Tum1p 0.040
YFH1 Yfh1p 0.039
YOL038C-A hypothetical protein 0.039
LEU2 Leu2p 0.039
SAP190 Sap190p 0.038
NGL2 Ngl2p 0.038
YLR264C-A hypothetical protein 0.038
YCK2 Yck2p 0.038
MF(ALPHA)2 Mf(alpha)2p 0.034
YLR162W hypothetical protein 0.034
SFT1 Sft1p 0.034
ATR1 Atr1p 0.034
DOG1 Dog1p 0.033
YPR157W hypothetical protein 0.033
GDS1 Gds1p 0.032
YBR016W hypothetical protein 0.032
YLR042C hypothetical protein 0.032
SFB2 Sfb2p 0.032
SPL2 Spl2p 0.031
PFS1 Pfs1p 0.031
KAE1 Kae1p 0.030
YAR068W hypothetical protein 0.030
MF(ALPHA)1 Mf(alpha)1p 0.030
TYE7 Tye7p 0.029
ZPS1 Zps1p 0.029
AVL9 Avl9p 0.029
ATP6 Atp6p 0.029
RNH70 Rnh70p 0.028
STS1 Sts1p 0.028
YIL151C hypothetical protein 0.028
URA3 Ura3p 0.028
YCK1 Yck1p 0.027
MTO1 Mto1p 0.027
TRM12 Trm12p 0.027
YML119W hypothetical protein 0.027
TAH1 Tah1p 0.026
PCC1 Pcc1p 0.025
YPL067C hypothetical protein 0.025
CHA1 Cha1p 0.025
NEO1 Neo1p 0.025
DEG1 Deg1p 0.025
UPS3 Ups3p 0.025
HPF1 Hpf1p 0.024
MRS2 Mrs2p 0.024
YBT1 Ybt1p 0.024
DML1 Dml1p 0.024
NDE1 Nde1p 0.024
SGE1 Sge1p 0.024
DIC1 Dic1p 0.024
BIO2 Bio2p 0.024
YBR013C hypothetical protein 0.023
YER186C hypothetical protein 0.023
RAM2 Ram2p 0.023
PHO8 Pho8p 0.023
AUA1 Aua1p 0.023
RIB1 Rib1p 0.023
YIR035C hypothetical protein 0.022