Drosophila melanogaster

94 known processes

sll (Dmel_CG7623)

slalom

(Aliases: l(3)S142214,CG7623,1422/14,anon-WO0172774.85,anon-WO0118547.555,Dmel\CG7623)

sll biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
carbohydrate derivative biosynthetic process GO:1901137 85 0.458
heparan sulfate proteoglycan biosynthetic process GO:0015012 10 0.327
proteoglycan biosynthetic process GO:0030166 10 0.285
carbohydrate derivative metabolic process GO:1901135 217 0.171
anterior posterior pattern specification GO:0009952 136 0.156
appendage morphogenesis GO:0035107 397 0.155
regionalization GO:0003002 416 0.154
imaginal disc derived wing vein specification GO:0007474 48 0.140
blastoderm segmentation GO:0007350 159 0.137
respiratory system development GO:0060541 213 0.131
cellular response to chemical stimulus GO:0070887 199 0.128
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.103
appendage development GO:0048736 401 0.103
glycoprotein metabolic process GO:0009100 41 0.102
transmembrane transport GO:0055085 139 0.101
proteoglycan metabolic process GO:0006029 10 0.099
response to organic substance GO:0010033 284 0.099
sulfur compound biosynthetic process GO:0044272 16 0.095
ion transport GO:0006811 145 0.091
eye development GO:0001654 323 0.090
camera type eye development GO:0043010 4 0.089
single organism biosynthetic process GO:0044711 206 0.083
transcription from rna polymerase ii promoter GO:0006366 368 0.082
regulation of localization GO:0032879 275 0.082
connective tissue development GO:0061448 3 0.072
Zebrafish
cellular protein modification process GO:0006464 438 0.071
cellular response to organic substance GO:0071310 132 0.069
endodermal cell fate commitment GO:0001711 3 0.066
chondroitin sulfate metabolic process GO:0030204 2 0.063
embryonic pattern specification GO:0009880 174 0.062
organic acid metabolic process GO:0006082 103 0.062
rna localization GO:0006403 115 0.062
glycoprotein biosynthetic process GO:0009101 41 0.056
segmentation GO:0035282 207 0.055
camera type eye morphogenesis GO:0048593 2 0.054
extracellular matrix organization GO:0030198 32 0.054
Zebrafish
immune system process GO:0002376 347 0.053
protein modification process GO:0036211 438 0.052
axis specification GO:0009798 167 0.051
imaginal disc derived appendage development GO:0048737 399 0.049
mesoderm development GO:0007498 78 0.047
establishment of organelle localization GO:0051656 122 0.047
protein catabolic process GO:0030163 101 0.047
wing disc morphogenesis GO:0007472 344 0.047
imaginal disc derived wing morphogenesis GO:0007476 337 0.045
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.045
columnar cuboidal epithelial cell development GO:0002066 249 0.045
oligosaccharide biosynthetic process GO:0009312 10 0.044
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.044
eye morphogenesis GO:0048592 260 0.043
positive regulation of transcription dna templated GO:0045893 266 0.043
vesicle mediated transport GO:0016192 381 0.042
positive regulation of multicellular organismal process GO:0051240 143 0.041
positive regulation of nucleic acid templated transcription GO:1903508 266 0.040
secretion GO:0046903 109 0.040
positive regulation of transport GO:0051050 92 0.040
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.039
secretory granule organization GO:0033363 6 0.038
stem cell maintenance GO:0019827 67 0.038
extracellular structure organization GO:0043062 46 0.038
Zebrafish
oligosaccharide metabolic process GO:0009311 18 0.037
regulation of bmp signaling pathway GO:0030510 23 0.037
regulation of pathway restricted smad protein phosphorylation GO:0060393 1 0.037
homeostatic process GO:0042592 199 0.037
bmp signaling pathway GO:0030509 27 0.037
small molecule metabolic process GO:0044281 305 0.034
catabolic process GO:0009056 409 0.033
regulation of anatomical structure size GO:0090066 163 0.033
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.033
dorsal ventral pattern formation GO:0009953 133 0.033
positive regulation of cell migration GO:0030335 2 0.033
olfactory behavior GO:0042048 97 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.032
stem cell development GO:0048864 79 0.032
mitotic nuclear division GO:0007067 213 0.031
establishment of vesicle localization GO:0051650 51 0.031
heparan sulfate proteoglycan metabolic process GO:0030201 10 0.031
protein glycosylation GO:0006486 32 0.030
establishment of localization in cell GO:0051649 402 0.030
oocyte dorsal ventral axis specification GO:0007310 34 0.029
stem cell differentiation GO:0048863 117 0.029
regulation of steroid metabolic process GO:0019218 2 0.029
sensory organ morphogenesis GO:0090596 260 0.029
organic substance transport GO:0071702 257 0.029
imaginal disc derived appendage morphogenesis GO:0035114 395 0.028
cellular response to endogenous stimulus GO:0071495 80 0.028
carbohydrate metabolic process GO:0005975 82 0.028
regulation of cell cycle GO:0051726 291 0.028
central nervous system development GO:0007417 201 0.028
taxis GO:0042330 304 0.027
Zebrafish
nitrogen compound transport GO:0071705 85 0.027
signal transduction downstream of smoothened GO:0007227 5 0.027
open tracheal system development GO:0007424 204 0.027
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.027
kidney development GO:0001822 3 0.027
digestive system development GO:0055123 149 0.027
cellular catabolic process GO:0044248 372 0.027
wnt signaling pathway GO:0016055 98 0.026
endomembrane system organization GO:0010256 119 0.026
oocyte axis specification GO:0007309 108 0.026
retina development in camera type eye GO:0060041 4 0.026
protein palmitoylation GO:0018345 2 0.026
secretion by cell GO:0032940 101 0.026
oxoacid metabolic process GO:0043436 103 0.026
periodic partitioning GO:0007365 29 0.026
aminoglycan biosynthetic process GO:0006023 11 0.026
Zebrafish
determination of adult lifespan GO:0008340 137 0.026
response to fungus GO:0009620 50 0.026
photoreceptor cell development GO:0042461 96 0.025
monocarboxylic acid transport GO:0015718 3 0.025
single organism carbohydrate metabolic process GO:0044723 72 0.025
embryonic axis specification GO:0000578 107 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
Zebrafish
post embryonic appendage morphogenesis GO:0035120 385 0.024
determination of ventral identity GO:0048264 1 0.024
positive regulation of secretion GO:0051047 22 0.024
synaptic vesicle localization GO:0097479 53 0.024
positive regulation of cell communication GO:0010647 250 0.024
limb development GO:0060173 1 0.024
cell motility GO:0048870 251 0.023
endocytosis GO:0006897 310 0.023
response to dsrna GO:0043331 15 0.023
guanosine containing compound catabolic process GO:1901069 74 0.023
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 3 0.023
detection of stimulus involved in sensory perception GO:0050906 92 0.022
cellular response to hexose stimulus GO:0071331 1 0.022
neuron fate commitment GO:0048663 50 0.022
chromosome organization GO:0051276 360 0.022
neuron projection guidance GO:0097485 241 0.022
Zebrafish
protein acylation GO:0043543 42 0.022
regulation of cell differentiation GO:0045595 302 0.022
kidney epithelium development GO:0072073 3 0.022
response to endogenous stimulus GO:0009719 119 0.022
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.022
o glycan processing GO:0016266 3 0.022
positive regulation of cell motility GO:2000147 3 0.022
cytoplasmic transport GO:0016482 130 0.021
epithelial cell differentiation GO:0030855 322 0.021
detection of visible light GO:0009584 38 0.021
tripartite regional subdivision GO:0007351 103 0.021
smoothened signaling pathway involved in ventral spinal cord patterning GO:0021910 0 0.021
localization of cell GO:0051674 257 0.021
limb morphogenesis GO:0035108 1 0.021
cuticle development GO:0042335 86 0.021
modification dependent macromolecule catabolic process GO:0043632 79 0.021
decapentaplegic signaling pathway GO:0008101 19 0.020
intracellular transport GO:0046907 228 0.020
regulation of transport GO:0051049 181 0.020
retina morphogenesis in camera type eye GO:0060042 2 0.020
organic substance catabolic process GO:1901575 308 0.020
immune system development GO:0002520 57 0.020
regulation of programmed cell death GO:0043067 152 0.020
negative regulation of gene expression GO:0010629 387 0.020
chemical homeostasis GO:0048878 92 0.020
skeletal muscle fiber development GO:0048741 3 0.020
protein modification by small protein conjugation GO:0032446 79 0.020
morphogenesis of an epithelium GO:0002009 276 0.020
determination of dorsal ventral asymmetry GO:0048262 3 0.020
dorsal closure GO:0007391 79 0.020
cellular response to monosaccharide stimulus GO:0071326 2 0.020
chemosensory behavior GO:0007635 106 0.020
macromolecule glycosylation GO:0043413 32 0.019
cell division GO:0051301 248 0.019
developmental maturation GO:0021700 172 0.019
nucleobase containing compound transport GO:0015931 56 0.019
glycosyl compound metabolic process GO:1901657 127 0.019
germ line stem cell maintenance GO:0030718 50 0.019
fibroblast growth factor receptor signaling pathway GO:0008543 10 0.019
forebrain development GO:0030900 2 0.019
hemopoiesis GO:0030097 46 0.019
cellular homeostasis GO:0019725 80 0.019
response to monosaccharide GO:0034284 4 0.019
extracellular matrix constituent secretion GO:0070278 4 0.019
positive regulation of biosynthetic process GO:0009891 316 0.018
anatomical structure homeostasis GO:0060249 97 0.018
embryonic organ development GO:0048568 50 0.018
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.018
innate immune response activating signal transduction GO:0002758 2 0.018
protein complex biogenesis GO:0070271 201 0.018
hematopoietic progenitor cell differentiation GO:0002244 1 0.018
response to organic cyclic compound GO:0014070 89 0.018
digestive tract development GO:0048565 149 0.018
developmental pigmentation GO:0048066 68 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
organelle fission GO:0048285 340 0.017
cell aging GO:0007569 2 0.017
spinal cord dorsal ventral patterning GO:0021513 1 0.017
spinal cord patterning GO:0021511 1 0.017
regulation of cellular response to growth factor stimulus GO:0090287 13 0.017
tube development GO:0035295 244 0.017
eye pigmentation GO:0048069 43 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.017
negative regulation of wnt signaling pathway GO:0030178 28 0.017
cell cycle arrest GO:0007050 4 0.017
proteolysis GO:0006508 192 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.016
enteroendocrine cell differentiation GO:0035883 1 0.016
sulfur compound metabolic process GO:0006790 59 0.016
detection of stimulus GO:0051606 156 0.016
single organism behavior GO:0044708 391 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
cellular chemical homeostasis GO:0055082 40 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
regulation of immune system process GO:0002682 176 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
myotube cell development GO:0014904 3 0.016
regulation of cellular localization GO:0060341 136 0.016
locomotory behavior GO:0007626 176 0.016
mesoderm morphogenesis GO:0048332 22 0.016
response to glucose GO:0009749 2 0.016
cellular protein catabolic process GO:0044257 83 0.016
dorsal ventral axis specification GO:0009950 66 0.016
epithelial tube morphogenesis GO:0060562 88 0.016
response to abiotic stimulus GO:0009628 341 0.015
cell cycle phase transition GO:0044770 140 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
protein maturation GO:0051604 71 0.015
anterior posterior axis specification embryo GO:0008595 103 0.015
regulation of nervous system development GO:0051960 248 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
heparin metabolic process GO:0030202 4 0.015
negative regulation of cell differentiation GO:0045596 143 0.015
cellular macromolecule localization GO:0070727 220 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
imaginal disc pattern formation GO:0007447 91 0.015
larval lymph gland hemocyte differentiation GO:0035168 11 0.015
regulation of catalytic activity GO:0050790 185 0.015
lymph gland development GO:0048542 28 0.015
carbohydrate biosynthetic process GO:0016051 17 0.015
positive regulation of signaling GO:0023056 243 0.015
vesicle localization GO:0051648 55 0.015
response to oxygen containing compound GO:1901700 200 0.015
regulation of multicellular organismal development GO:2000026 414 0.015
morphogenesis of embryonic epithelium GO:0016331 94 0.015
multicellular organismal homeostasis GO:0048871 41 0.015
negative regulation of developmental process GO:0051093 201 0.014
protein ubiquitination GO:0016567 70 0.014
cell cycle g1 s phase transition GO:0044843 31 0.014
lipid metabolic process GO:0006629 121 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
regulation of cell substrate adhesion GO:0010810 2 0.014
ocellus pigmentation GO:0033060 19 0.014
intracellular signal transduction GO:0035556 300 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.014
cellular ketone metabolic process GO:0042180 24 0.014
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
convergent extension GO:0060026 2 0.014
innate immune response GO:0045087 144 0.014
regulation of apoptotic process GO:0042981 130 0.014
pigmentation GO:0043473 75 0.014
eye photoreceptor cell development GO:0042462 81 0.014
positive regulation of signal transduction GO:0009967 223 0.014
gastrulation GO:0007369 70 0.014
compound eye development GO:0048749 307 0.013
macromolecule catabolic process GO:0009057 161 0.013
anion homeostasis GO:0055081 3 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
regulation of embryonic development GO:0045995 68 0.013
regulation of developmental growth GO:0048638 174 0.013
cellular response to carbohydrate stimulus GO:0071322 4 0.013
ion homeostasis GO:0050801 55 0.013
tube morphogenesis GO:0035239 191 0.013
cellular lipid metabolic process GO:0044255 83 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
aging GO:0007568 143 0.013
negative regulation of epithelial cell proliferation GO:0050680 4 0.013
single organism catabolic process GO:0044712 228 0.013
sterol homeostasis GO:0055092 4 0.013
regulation of smoothened signaling pathway GO:0008589 28 0.013
epithelial cell development GO:0002064 274 0.013
aminoglycan metabolic process GO:0006022 18 0.013
Zebrafish
programmed cell death GO:0012501 257 0.013
chitin based cuticle development GO:0040003 49 0.013
pupal development GO:0035209 11 0.013
tissue morphogenesis GO:0048729 297 0.013
inositol lipid mediated signaling GO:0048017 4 0.013
smoothened signaling pathway GO:0007224 49 0.013
macromolecular complex assembly GO:0065003 256 0.013
digestive tract morphogenesis GO:0048546 127 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
response to starvation GO:0042594 97 0.013
dendrite morphogenesis GO:0048813 199 0.013
positive regulation of bmp signaling pathway GO:0030513 5 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
protein processing GO:0016485 68 0.013
regulation of protein metabolic process GO:0051246 256 0.013
response to external biotic stimulus GO:0043207 293 0.013
immune response GO:0006955 246 0.013
oocyte differentiation GO:0009994 145 0.013
dendrite development GO:0016358 204 0.012
extrinsic apoptotic signaling pathway GO:0097191 1 0.012
endodermal cell differentiation GO:0035987 3 0.012
response to organophosphorus GO:0046683 2 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
negative regulation of cell communication GO:0010648 223 0.012
morphogenesis of follicular epithelium GO:0016333 36 0.012
segment polarity determination GO:0007367 25 0.012
axis elongation GO:0003401 3 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
retinal ganglion cell axon guidance GO:0031290 12 0.012
Zebrafish
oocyte construction GO:0007308 112 0.012
response to virus GO:0009615 28 0.012
regulation of cellular catabolic process GO:0031329 157 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
regulation of reproductive process GO:2000241 54 0.012
chondroitin sulfate proteoglycan metabolic process GO:0050654 3 0.012
cell fate specification GO:0001708 71 0.012
gland development GO:0048732 191 0.012
imaginal disc derived leg morphogenesis GO:0007480 80 0.012
negative regulation of organelle organization GO:0010639 56 0.012
positive regulation of axon guidance GO:1902669 1 0.012
autophagic vacuole assembly GO:0000045 2 0.012
regulation of intracellular transport GO:0032386 64 0.012
response to hexose GO:0009746 3 0.012
cholesterol homeostasis GO:0042632 3 0.012
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.012
organophosphate metabolic process GO:0019637 195 0.012
establishment of synaptic vesicle localization GO:0097480 50 0.012
regulation of neuron differentiation GO:0045664 103 0.012
glandular epithelial cell differentiation GO:0002067 1 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.011
negative regulation of signaling GO:0023057 219 0.011
gene silencing by mirna GO:0035195 22 0.011
endoderm formation GO:0001706 3 0.011
negative regulation of apoptotic process GO:0043066 63 0.011
synapse organization GO:0050808 196 0.011
regulation of organ formation GO:0003156 3 0.011
ameboidal type cell migration GO:0001667 151 0.011
oocyte development GO:0048599 124 0.011
production of small rna involved in gene silencing by rna GO:0070918 15 0.011
branching involved in open tracheal system development GO:0060446 45 0.011
phagocytosis GO:0006909 215 0.011
nucleotide transmembrane transport GO:1901679 7 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
endosomal transport GO:0016197 44 0.011
immune response activating signal transduction GO:0002757 2 0.011
positive regulation of gene expression GO:0010628 290 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
response to other organism GO:0051707 293 0.011
regulation of molecular function GO:0065009 217 0.011
ncrna 3 end processing GO:0043628 17 0.011
positive regulation of immune system process GO:0002684 68 0.011
post embryonic hemopoiesis GO:0035166 17 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.011
embryonic heart tube development GO:0035050 22 0.011
cellular amine metabolic process GO:0044106 12 0.011
protein localization to organelle GO:0033365 82 0.011
embryonic morphogenesis GO:0048598 206 0.011
leg disc development GO:0035218 92 0.011
glycosylation GO:0070085 36 0.011
synaptic transmission GO:0007268 288 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
wing disc pattern formation GO:0035222 66 0.011
sensory perception GO:0007600 196 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
golgi organization GO:0007030 66 0.010
regulation of decapentaplegic signaling pathway GO:0090097 8 0.010
hematopoietic or lymphoid organ development GO:0048534 57 0.010
positive regulation of pathway restricted smad protein phosphorylation GO:0010862 1 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
molting cycle process GO:0022404 29 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
rna processing GO:0006396 147 0.010
negative regulation of cell cycle GO:0045786 116 0.010
cation homeostasis GO:0055080 51 0.010
eye antennal disc development GO:0035214 60 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
stem cell division GO:0017145 69 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
organelle localization GO:0051640 148 0.010
cell death GO:0008219 279 0.010
neuron fate specification GO:0048665 12 0.010
guanosine containing compound metabolic process GO:1901068 74 0.010
hindgut development GO:0061525 58 0.010
ketone biosynthetic process GO:0042181 16 0.010
regulation of neurogenesis GO:0050767 158 0.010
dna metabolic process GO:0006259 227 0.010

sll disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.027
cardiovascular system disease DOID:1287 0 0.025
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015
bone disease DOID:0080001 0 0.013
musculoskeletal system disease DOID:17 0 0.013
connective tissue disease DOID:65 0 0.013
sensory system disease DOID:0050155 0 0.013
eye and adnexa disease DOID:1492 0 0.013
disease of metabolism DOID:0014667 0 0.012
inherited metabolic disorder DOID:655 0 0.012