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Drosophila melanogaster

4 genes annotated in fly

phosphatidylinositol 3 kinase signaling

A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "phosphatidylinositol 3 kinase signaling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "phosphatidylinositol 3 kinase signaling" (in gray)

Name	Description	Probability	Func Analog Organism
Atg18	Autophagy-specific gene 18	0.169
chico	CG5686 gene product from transcript CG5686-RB	0.120	Human
ena	enabled	0.102
lea	leak	0.088
Pk61C	Protein kinase 61C	0.086
Pi3K92E	CG4141 gene product from transcript CG4141-RB	0.083
jeb	jelly belly	0.077
Tl	Toll	0.071
NFAT	NFAT homolog	0.064
Alk	CG8250 gene product from transcript CG8250-RA	0.061	Human
Atg2	Autophagy-specific gene 2	0.060
Stam	Signal transducing adaptor molecule	0.058
S6k	RPS6-p70-protein kinase	0.058
Wnk	CG7177 gene product from transcript CG7177-RA	0.057
ex	expanded	0.057
stai	stathmin	0.054
step	steppke	0.054
Pp2B-14D	Protein phosphatase 2B at 14D	0.053
Atg8a	Autophagy-specific gene 8a	0.047
wun	wunen	0.047
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.044
Pi3K59F	Phosphotidylinositol 3 kinase 59F	0.042
Pten	CG5671 gene product from transcript CG5671-RB	0.041
Indy	I'm not dead yet	0.040
kis	kismet	0.040
dnc	dunce	0.039
rst	roughest	0.039
LIMK1	LIM-kinase1	0.038
oys	oysgedart	0.038
Atg4	Autophagy-specific gene 4	0.032
drl	derailed	0.032
baz	bazooka	0.032
cher	cheerio	0.030
Rheb	CG1081 gene product from transcript CG1081-RA	0.030
tok	tolkin	0.029
spi	spitz	0.028
HLH106	Helix loop helix protein 106	0.028
Marf	Mitochondrial assembly regulatory factor	0.028
cnc	cap-n-collar	0.027
ems	empty spiracles	0.027
Atg9	Autophagy-specific gene 9	0.027
myoglianin	CG1838 gene product from transcript CG1838-RD	0.027
Pvr	PDGF- and VEGF-receptor related	0.027	Human Mouse
repo	reversed polarity	0.027
klg	klingon	0.027
tomosyn	CG17762 gene product from transcript CG17762-RB	0.026
tutl	turtle	0.026
X11L	CG5675 gene product from transcript CG5675-RB	0.025
trio	CG18214 gene product from transcript CG18214-RA	0.025
Cbl	CG7037 gene product from transcript CG7037-RB	0.025	Human
Akt1	CG4006 gene product from transcript CG4006-RA	0.025
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.024
Ephrin	CG1862 gene product from transcript CG1862-RA	0.024
fra	frazzled	0.024
Wnt5	Wnt oncogene analog 5	0.023
rut	rutabaga	0.023
Eip71CD	Ecdysone-induced protein 28/29kD	0.023
pdm3	pou domain motif 3	0.022
Atg7	Autophagy-specific gene 7	0.022
ImpL2	Ecdysone-inducible gene L2	0.022
Liprin-alpha	CG11199 gene product from transcript CG11199-RB	0.022
trn	tartan	0.022
Mob4	CG3403 gene product from transcript CG3403-RA	0.021
Nrx-IV	Neurexin IV	0.020
jing	CG9397 gene product from transcript CG9397-RI	0.020
scyl	scylla	0.020
slbo	slow border cells	0.020
Dcr-2	Dicer-2	0.020
CG12424	CG12424 gene product from transcript CG12424-RC	0.019
B-H1	BarH1	0.019
babo	baboon	0.019
Fer2LCH	Ferritin 2 light chain homologue	0.019
CG3004	CG3004 gene product from transcript CG3004-RA	0.019
Smox	Smad on X	0.019
ird1	immune response deficient 1	0.019
Lrrk	Leucine-rich repeat kinase	0.019
comt	comatose	0.018
plexB	plexin B	0.018
CG4699	CG4699 gene product from transcript CG4699-RJ	0.018
CG3573	CG3573 gene product from transcript CG3573-RA	0.018
Fak56D	Focal Adhesion Kinase	0.018	Human
lab	labial	0.018
ap	apterous	0.018
side	sidestep	0.018
Nf1	Neurofibromin 1	0.018	Mouse
TppII	tripeptidyl-peptidase II	0.017
RASSF8	CG5053 gene product from transcript CG5053-RA	0.017
pkaap	CG4132 gene product from transcript CG4132-RA	0.017
CG5731	CG5731 gene product from transcript CG5731-RA	0.017
Ptp52F	CG18243 gene product from transcript CG18243-RB	0.017
chrb	charybde	0.017
CG16778	CG16778 gene product from transcript CG16778-RA	0.016
CG5508	CG5508 gene product from transcript CG5508-RA	0.016
Krn	Keren	0.016
CkIIalpha	Casein kinase II alpha subunit	0.016
Fas3	Fasciclin 3	0.016
tld	tolloid	0.016
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.016
Cul-5	Cullin-5	0.016
mbc	myoblast city	0.016
atl	atlastin	0.016
CG31033	CG31033 gene product from transcript CG31033-RC	0.016
Cdk4	Cyclin-dependent kinase 4	0.016
Tbh	Tyramine beta hydroxylase	0.016
Utx	CG5640 gene product from transcript CG5640-RD	0.016
mub	mushroom-body expressed	0.015
Ork1	Open rectifier K[+] channel 1	0.015
CG5871	CG5871 gene product from transcript CG5871-RA	0.015
S6kII	RPS6-protein kinase-II	0.015
mtSSB	mitochondrial single stranded DNA-binding protein	0.015
nudE	CG8104 gene product from transcript CG8104-RB	0.015
Socs36E	Suppressor of cytokine signaling at 36E	0.015
sl	small wing	0.015
krz	kurtz	0.015
tai	taiman	0.015
SoxN	SoxNeuro	0.015
Atg1	Autophagy-specific gene 1	0.014
RagA	CG11968 gene product from transcript CG11968-RA	0.014
kst	karst	0.014
nvy	nervy	0.014
Itp-r83A	Inositol 1,4,5,-tris-phosphate receptor	0.014
CG11877	CG11877 gene product from transcript CG11877-RA	0.014
E23	Early gene at 23	0.014
CG42574	CG42574 gene product from transcript CG42574-RE	0.014
CG8709	CG8709 gene product from transcript CG8709-RK	0.014
sll	slalom	0.014
usp	ultraspiracle	0.014
neuroligin	CG13772 gene product from transcript CG13772-RA	0.014
Ten-m	Tenascin major	0.014
ogre	optic ganglion reduced	0.014
Shc	SHC-adaptor protein	0.014
Sply	Sphingosine-1-phosphate lyase	0.014
pdm2	POU domain protein 2	0.014
trpml	transient receptor potential mucolipin	0.014
byn	brachyenteron	0.014
dnt	doughnut on 2	0.013
Adar	Adenosine deaminase acting on RNA	0.013
dve	defective proventriculus	0.013
glec	gliolectin	0.013
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.013
tll	tailless	0.013
shrb	shrub	0.013
dock	dreadlocks	0.013
Fs	Follistatin	0.013
beat-Ic	beaten path Ic	0.013
Rpn5	CG1100 gene product from transcript CG1100-RA	0.013
CBP	sarcoplasmic calcium-binding protein	0.013
dlt	discs lost	0.013
kal-1	CG6173 gene product from transcript CG6173-RA	0.013
Hcf	Host cell factor	0.013
nerfin-1	nervous fingers 1	0.013
CG14299	CG14299 gene product from transcript CG14299-RC	0.013
Lnk	CG17367 gene product from transcript CG17367-RC	0.013
PTP-ER	Protein tyrosine phosphatase-ERK/Enhancer of Ras1	0.013
Spn27A	Serpin 27A	0.013
dm	diminutive	0.012
ATP7	CG1886 gene product from transcript CG1886-RB	0.012
milt	milton	0.012
Sara	Smad anchor for receptor activation	0.012
CG1021	CG1021 gene product from transcript CG1021-RE	0.012
abs	abstrakt	0.012
kay	kayak	0.012
mrt	martik	0.012
egl	egalitarian	0.012
futsch	CG34387 gene product from transcript CG34387-RC	0.012
bin	biniou	0.012
Ac3	CG1506 gene product from transcript CG1506-RA	0.012
Atx2	Ataxin-2	0.012
fkh	fork head	0.012
slif	slimfast	0.012
pan	pangolin	0.012
Keap1	CG3962 gene product from transcript CG3962-RC	0.012
CG30409	CG30409 gene product from transcript CG30409-RA	0.012
Vrp1	Verprolin 1	0.012
LanB2	Laminin B2	0.012
Spargel	CG9809 gene product from transcript CG9809-RB	0.012
Dh	Diuretic hormone	0.012
betaInt-nu	beta[nu] integrin	0.011
pip	pipe	0.011
l(2)k16918	lethal (2) k16918	0.011
CG3760	CG3760 gene product from transcript CG3760-RB	0.011
Trap1	CG3152 gene product from transcript CG3152-RA	0.011
Hmgs	HMG Coenzyme A synthase	0.011
Nrt	Neurotactin	0.011
toc	toucan	0.011
nord	CG30418 gene product from transcript CG30418-RA	0.011
CG11138	CG11138 gene product from transcript CG11138-RC	0.011
sqz	squeeze	0.011
amn	amnesiac	0.011
zfh1	Zn finger homeodomain 1	0.011
CG5931	CG5931 gene product from transcript CG5931-RA	0.011
Klp68D	Kinesin-like protein at 68D	0.011
pigeon	CG10739 gene product from transcript CG10739-RB	0.011
ade3	adenosine 3	0.011
Myo61F	Myosin 61F	0.011
PGRP-SC2	CG14745 gene product from transcript CG14745-RA	0.011
CG9650	CG9650 gene product from transcript CG9650-RG	0.011
CG7112	CG7112 gene product from transcript CG7112-RB	0.011
drk	downstream of receptor kinase	0.011
eas	easily shocked	0.011
vkg	viking	0.011
hppy	happyhour	0.011
ttv	tout-velu	0.011
Gyc76C	Guanylyl cyclase at 76C	0.011
kermit	CG11546 gene product from transcript CG11546-RB	0.011
Nrx-1	Neurexin 1	0.011
mib2	mind bomb 2	0.011
CG12001	CG12001 gene product from transcript CG12001-RA	0.011
slp1	sloppy paired 1	0.011
path	pathetic	0.011
CG6664	CG6664 gene product from transcript CG6664-RC	0.011
Rpn2	CG11888 gene product from transcript CG11888-RA	0.011
CG31998	CG31998 gene product from transcript CG31998-RA	0.011
Acer	Angiotensin-converting enzyme-related	0.010
Pvf2	PDGF- and VEGF-related factor 2	0.010
CG6191	CG6191 gene product from transcript CG6191-RA	0.010
Prat2	Phosphoribosylamidotransferase 2	0.010
CG14562	CG14562 gene product from transcript CG14562-RA	0.010
Cdk5alpha	Cdk5 activator-like protein	0.010
spas	spastin	0.010
FucTA	CG6869 gene product from transcript CG6869-RA	0.010
E5	CG9930 gene product from transcript CG9930-RA	0.010
CG9139	CG9139 gene product from transcript CG9139-RA	0.010
CG4857	CG4857 gene product from transcript CG4857-RD	0.010
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.010
CG9934	CG9934 gene product from transcript CG9934-RB	0.010
Gadd45	CG11086 gene product from transcript CG11086-RA	0.010