Drosophila melanogaster

214 known processes

p38b (Dmel_CG7393)

CG7393 gene product from transcript CG7393-RA

(Aliases: dp38b,186F5S,D-p38,p38beta,p38 MAPK,D-p38 MAPK,Dp38,CG7393,p38,p38B,p38 beta,anon-sts23,ESTS:186F5S,BG:DS00797.3,Dm p38b,D-p38b,Mpk34C,Dmel\CG7393)

p38b biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to oxygen radical GO:0000305 3 0.994
Worm
determination of adult lifespan GO:0008340 137 0.982
immune response GO:0006955 246 0.960
response to oxidative stress GO:0006979 86 0.959
response to superoxide GO:0000303 3 0.950
Worm
innate immune response GO:0045087 144 0.915
cellular response to oxidative stress GO:0034599 28 0.914
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.900
intracellular signal transduction GO:0035556 300 0.896
defense response to fungus GO:0050832 48 0.878
positive regulation of signal transduction GO:0009967 223 0.868
response to biotic stimulus GO:0009607 294 0.846
regulation of intracellular signal transduction GO:1902531 236 0.837
Fly
response to bacterium GO:0009617 198 0.836
negative regulation of cell communication GO:0010648 223 0.825
Mouse Fly
response to external biotic stimulus GO:0043207 293 0.815
negative regulation of signaling GO:0023057 219 0.808
Mouse Fly
regulation of multi organism process GO:0043900 131 0.807
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.803
Fly
negative regulation of response to stimulus GO:0048585 258 0.798
Mouse Fly
stress activated mapk cascade GO:0051403 52 0.779
Mouse Rat Worm Fly
negative regulation of signal transduction GO:0009968 206 0.766
Mouse Fly
positive regulation of response to stimulus GO:0048584 323 0.759
paracrine signaling GO:0038001 7 0.707
autophagy GO:0006914 108 0.677
Fly
positive regulation of biosynthetic process GO:0009891 316 0.674
Yeast Mouse Worm
response to other organism GO:0051707 293 0.671
immune system process GO:0002376 347 0.665
regulation of response to biotic stimulus GO:0002831 63 0.662
Fly
mapk cascade GO:0000165 107 0.622
programmed cell death GO:0012501 257 0.606
Worm
regulation of phosphate metabolic process GO:0019220 210 0.589
aging GO:0007568 143 0.578
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.575
regulation of response to stress GO:0080134 200 0.574
cellular response to chemical stimulus GO:0070887 199 0.573
regulation of cellular response to stress GO:0080135 89 0.570
death GO:0016265 284 0.557
Worm
cellular response to reactive oxygen species GO:0034614 14 0.547
defense response GO:0006952 300 0.532
cellular response to arsenic containing substance GO:0071243 6 0.523
jnk cascade GO:0007254 50 0.504
Fly
negative regulation of phosphorylation GO:0042326 35 0.492
Fly
homeostatic process GO:0042592 199 0.488
Mouse
regulation of transferase activity GO:0051338 58 0.484
Fly
regulation of immune system process GO:0002682 176 0.484
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.482
Yeast Mouse Worm
regulation of stress activated mapk cascade GO:0032872 41 0.482
Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.476
Human
regulation of multicellular organismal development GO:2000026 414 0.457
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.456
Human
melanin metabolic process GO:0006582 47 0.450
Fly
cellular response to starvation GO:0009267 61 0.442
bmp signaling pathway GO:0030509 27 0.438
regulation of immune effector process GO:0002697 52 0.431
regulation of molecular function GO:0065009 217 0.401
Fly
mucosal immune response GO:0002385 10 0.387
Fly
regulation of phosphorylation GO:0042325 147 0.380
response to extracellular stimulus GO:0009991 116 0.369
immune response regulating signaling pathway GO:0002764 2 0.366
cellular response to external stimulus GO:0071496 66 0.360
stress activated protein kinase signaling cascade GO:0031098 55 0.357
Mouse Rat Worm Fly
regulation of catabolic process GO:0009894 170 0.354
Fly
regulation of autophagy GO:0010506 62 0.350
Fly
cell death GO:0008219 279 0.349
Worm
regulation of anatomical structure size GO:0090066 163 0.347
molting cycle chitin based cuticle GO:0007591 56 0.346
regulation of protein modification process GO:0031399 112 0.342
defense response to bacterium GO:0042742 178 0.341
regulation of response to external stimulus GO:0032101 115 0.341
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.340
Yeast Mouse Worm
regulation of mapk cascade GO:0043408 92 0.333
Fly
intrinsic apoptotic signaling pathway GO:0097193 16 0.333
phosphorylation GO:0016310 294 0.332
regulation of jnk cascade GO:0046328 40 0.332
Fly
cellular response to nutrient levels GO:0031669 62 0.330
cellular response to organic substance GO:0071310 132 0.327
transcription from rna polymerase ii promoter GO:0006366 368 0.324
Yeast Mouse Worm
positive regulation of immune response GO:0050778 63 0.321
negative regulation of immune system process GO:0002683 50 0.316
Fly
regulation of cellular response to oxidative stress GO:1900407 4 0.312
peptide metabolic process GO:0006518 80 0.308
growth GO:0040007 359 0.301
immune response activating signal transduction GO:0002757 2 0.291
small molecule metabolic process GO:0044281 305 0.288
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.285
enzyme linked receptor protein signaling pathway GO:0007167 179 0.282
negative regulation of multicellular organismal process GO:0051241 142 0.281
positive regulation of autophagy GO:0010508 21 0.279
Fly
multicellular organismal aging GO:0010259 140 0.278
macromolecule catabolic process GO:0009057 161 0.271
regulation of immune response GO:0050776 118 0.265
defense response to other organism GO:0098542 225 0.265
developmental growth GO:0048589 280 0.257
regulation of multicellular organism growth GO:0040014 40 0.256
cellular response to extracellular stimulus GO:0031668 64 0.254
response to ionizing radiation GO:0010212 32 0.253
Human
regulation of cell differentiation GO:0045595 302 0.248
Yeast Mouse
positive regulation of cell size GO:0045793 21 0.237
catabolic process GO:0009056 409 0.237
Fly
pattern recognition receptor signaling pathway GO:0002221 2 0.232
negative regulation of intracellular signal transduction GO:1902532 57 0.226
Fly
regulation of protein phosphorylation GO:0001932 64 0.225
negative regulation of apoptotic process GO:0043066 63 0.223
regulation of protein kinase activity GO:0045859 51 0.220
Fly
regulation of programmed cell death GO:0043067 152 0.213
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.213
Fly
regionalization GO:0003002 416 0.205
positive regulation of multicellular organismal process GO:0051240 143 0.204
regulation of innate immune response GO:0045088 71 0.203
response to organic substance GO:0010033 284 0.197
cellular protein modification process GO:0006464 438 0.197
cellular amide metabolic process GO:0043603 80 0.197
apoptotic process GO:0006915 159 0.196
positive regulation of signaling GO:0023056 243 0.195
positive regulation of immune effector process GO:0002699 28 0.194
oxoacid metabolic process GO:0043436 103 0.194
Mouse
regulation of apoptotic process GO:0042981 130 0.188
antibacterial humoral response GO:0019731 44 0.187
Fly
heart contraction GO:0060047 26 0.184
single organism intracellular transport GO:1902582 207 0.179
Mouse
myotube cell development GO:0014904 3 0.178
Mouse
organic hydroxy compound metabolic process GO:1901615 83 0.178
Fly
regulation of kinase activity GO:0043549 53 0.177
Fly
regulation of catalytic activity GO:0050790 185 0.175
Fly
signal transduction by phosphorylation GO:0023014 107 0.174
imaginal disc derived appendage development GO:0048737 399 0.174
anatomical structure homeostasis GO:0060249 97 0.174
phagocytosis GO:0006909 215 0.172
Fly
cell migration GO:0016477 238 0.170
Fly
organic substance transport GO:0071702 257 0.165
Mouse
nucleocytoplasmic transport GO:0006913 72 0.165
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.164
Yeast Mouse Worm
response to fungus GO:0009620 50 0.159
negative regulation of stress activated protein kinase signaling cascade GO:0070303 20 0.158
Fly
regulation of defense response GO:0031347 102 0.154
melanization defense response GO:0035006 45 0.152
Fly
protein localization GO:0008104 284 0.152
Mouse Worm
positive regulation of cellular biosynthetic process GO:0031328 316 0.151
Yeast Mouse Worm
ameboidal type cell migration GO:0001667 151 0.149
Fly
defense response to virus GO:0051607 23 0.140
regulation of bmp signaling pathway GO:0030510 23 0.139
immune effector process GO:0002252 98 0.137
response to radiation GO:0009314 155 0.136
Human
establishment of protein localization GO:0045184 163 0.136
Mouse
mitochondrion organization GO:0007005 65 0.135
gtp metabolic process GO:0046039 72 0.133
appendage development GO:0048736 401 0.133
columnar cuboidal epithelial cell development GO:0002066 249 0.132
Fly
regulation of growth GO:0040008 233 0.131
organonitrogen compound metabolic process GO:1901564 318 0.130
response to nutrient levels GO:0031667 114 0.130
mitochondrion degradation GO:0000422 8 0.130
response to starvation GO:0042594 97 0.130
negative regulation of developmental process GO:0051093 201 0.126
Yeast
cell motility GO:0048870 251 0.123
Fly
regulation of wnt signaling pathway GO:0030111 68 0.122
Mouse
embryonic development via the syncytial blastoderm GO:0001700 148 0.121
Fly
regulation of cellular component biogenesis GO:0044087 201 0.121
positive regulation of phosphate metabolic process GO:0045937 139 0.120
cellular amino acid metabolic process GO:0006520 61 0.117
regulation of production of molecular mediator of immune response GO:0002700 44 0.117
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.117
negative regulation of immune response GO:0050777 39 0.114
Fly
positive regulation of cell communication GO:0010647 250 0.114
response to oxygen containing compound GO:1901700 200 0.113
negative regulation of phosphorus metabolic process GO:0010563 45 0.113
Fly
positive regulation of protein metabolic process GO:0051247 128 0.113
protein modification process GO:0036211 438 0.113
negative regulation of stress activated mapk cascade GO:0032873 19 0.110
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.108
Yeast Mouse Worm
positive regulation of production of molecular mediator of immune response GO:0002702 28 0.108
cellular lipid metabolic process GO:0044255 83 0.107
Mouse
ovarian follicle cell development GO:0030707 248 0.105
Fly
organ or tissue specific immune response GO:0002251 10 0.103
Fly
spindle assembly GO:0051225 80 0.103
positive regulation of programmed cell death GO:0043068 62 0.103
response to endogenous stimulus GO:0009719 119 0.102
cellular response to cadmium ion GO:0071276 6 0.101
positive regulation of developmental process GO:0051094 143 0.098
protein import into nucleus GO:0006606 51 0.098
Mouse
regulation of protein metabolic process GO:0051246 256 0.097
cellular protein localization GO:0034613 160 0.097
Mouse Worm
response to hydrogen peroxide GO:0042542 11 0.097
positive regulation of gene expression GO:0010628 290 0.096
Yeast Mouse Worm
cell growth GO:0016049 108 0.095
Fly
heart process GO:0003015 37 0.095
single organism nuclear import GO:1902593 51 0.094
Mouse
localization of cell GO:0051674 257 0.094
Fly
hyperosmotic response GO:0006972 1 0.093
Yeast Worm
molting cycle GO:0042303 56 0.093
myotube differentiation GO:0014902 46 0.092
Mouse
regulation of developmental growth GO:0048638 174 0.091
epithelial cell differentiation GO:0030855 322 0.091
Fly
lipid homeostasis GO:0055088 33 0.090
epithelial cell development GO:0002064 274 0.090
Fly
response to axon injury GO:0048678 12 0.089
Fly
cytoskeleton dependent intracellular transport GO:0030705 44 0.089
activation of innate immune response GO:0002218 4 0.089
positive regulation of catalytic activity GO:0043085 118 0.088
organonitrogen compound biosynthetic process GO:1901566 117 0.088
notch signaling pathway GO:0007219 120 0.085
vesicle mediated transport GO:0016192 381 0.084
Fly
guanosine containing compound catabolic process GO:1901069 74 0.084
innate immune response activating signal transduction GO:0002758 2 0.083
autophagic vacuole assembly GO:0000045 2 0.079
regulation of cell size GO:0008361 63 0.077
positive regulation of rna metabolic process GO:0051254 271 0.077
Yeast Mouse Worm
positive regulation of defense response GO:0031349 59 0.077
response to virus GO:0009615 28 0.076
regulation of cell death GO:0010941 173 0.076
regulation of cellular response to insulin stimulus GO:1900076 17 0.075
regulation of antimicrobial humoral response GO:0002759 50 0.074
Fly
reactive oxygen species metabolic process GO:0072593 22 0.074
positive regulation of protein modification process GO:0031401 58 0.073
macromolecular complex assembly GO:0065003 256 0.072
covalent chromatin modification GO:0016569 106 0.072
antimicrobial peptide production GO:0002775 46 0.072
regulation of localization GO:0032879 275 0.071
Mouse Worm
organic substance catabolic process GO:1901575 308 0.071
taxis GO:0042330 304 0.070
Fly
cellular catabolic process GO:0044248 372 0.070
Fly
terminal button organization GO:0072553 19 0.069
positive regulation of cellular catabolic process GO:0031331 95 0.069
Fly
negative regulation of molecular function GO:0044092 51 0.069
Fly
regulation of cell development GO:0060284 215 0.067
Mouse
positive regulation of protein transport GO:0051222 37 0.066
Mouse
positive regulation of protein phosphorylation GO:0001934 34 0.066
heart morphogenesis GO:0003007 32 0.065
positive regulation of phosphorylation GO:0042327 87 0.065
single organism catabolic process GO:0044712 228 0.064
humoral immune response GO:0006959 117 0.064
Fly
establishment of localization in cell GO:0051649 402 0.063
Mouse
negative regulation of kinase activity GO:0033673 16 0.062
Fly
regulation of defense response to virus GO:0050688 14 0.061
regulation of reactive oxygen species metabolic process GO:2000377 8 0.061
Human
organelle fission GO:0048285 340 0.060
organophosphate metabolic process GO:0019637 195 0.060
regulation of cell proliferation GO:0042127 163 0.059
positive regulation of catabolic process GO:0009896 105 0.059
Fly
single organism biosynthetic process GO:0044711 206 0.058
Yeast
carboxylic acid metabolic process GO:0019752 92 0.058
Mouse
eggshell formation GO:0030703 105 0.058
Fly
negative regulation of cell death GO:0060548 81 0.058
neurological system process GO:0050877 358 0.058
regulation of cellular component size GO:0032535 98 0.058
cellular response to endogenous stimulus GO:0071495 80 0.057
cell aging GO:0007569 2 0.057
Human
nucleotide catabolic process GO:0009166 109 0.056
negative regulation of transcription dna templated GO:0045892 237 0.056
nuclear import GO:0051170 51 0.055
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.054
negative regulation of mapk cascade GO:0043409 23 0.054
Fly
regulation of response to oxidative stress GO:1902882 4 0.053
negative regulation of programmed cell death GO:0043069 72 0.052
regulation of protein localization GO:0032880 76 0.052
Mouse Worm
intracellular transport GO:0046907 228 0.052
Mouse
peptidoglycan metabolic process GO:0000270 3 0.051
regulation of adult chitin containing cuticle pigmentation GO:0048082 13 0.051
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.051
positive regulation of intracellular signal transduction GO:1902533 116 0.051
carbohydrate derivative catabolic process GO:1901136 118 0.049
positive regulation of multi organism process GO:0043902 40 0.049
response to peptide GO:1901652 29 0.048
Mouse
apoptotic signaling pathway GO:0097190 27 0.048
regulation of insulin receptor signaling pathway GO:0046626 17 0.048
organic acid metabolic process GO:0006082 103 0.048
Mouse
intracellular protein transport GO:0006886 104 0.047
Mouse
muscle organ development GO:0007517 127 0.047
Mouse
defense response to gram negative bacterium GO:0050829 94 0.046
Worm
endocytosis GO:0006897 310 0.046
Fly
positive regulation of defense response to bacterium GO:1900426 23 0.046
positive regulation of protein kinase activity GO:0045860 25 0.046
regulation of map kinase activity GO:0043405 17 0.046
Fly
cellular macromolecule localization GO:0070727 220 0.045
Mouse Worm
regulation of cellular catabolic process GO:0031329 157 0.045
Fly
negative regulation of protein phosphorylation GO:0001933 17 0.045
Fly
connective tissue development GO:0061448 3 0.045
Mouse
regulation of notch signaling pathway GO:0008593 100 0.045
response to peptidoglycan GO:0032494 2 0.044
protein localization to nucleus GO:0034504 55 0.044
Mouse Worm
regulation of protein import into nucleus GO:0042306 28 0.043
Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.043
negative regulation of cell differentiation GO:0045596 143 0.043
Yeast
response to lipopolysaccharide GO:0032496 4 0.043
Human Mouse
multicellular organismal homeostasis GO:0048871 41 0.043
dna damage checkpoint GO:0000077 78 0.043
Mouse
regulation of steroid metabolic process GO:0019218 2 0.042
signal transduction in response to dna damage GO:0042770 3 0.041
Human
canonical wnt signaling pathway GO:0060070 21 0.040
Mouse
molting cycle process GO:0022404 29 0.039
axon guidance GO:0007411 233 0.039
Fly
chromosome organization GO:0051276 360 0.039
cellular response to oxygen containing compound GO:1901701 79 0.039
cellular response to ionizing radiation GO:0071479 15 0.039
Human
response to organonitrogen compound GO:0010243 75 0.038
Mouse
tor signaling GO:0031929 32 0.038
skeletal muscle organ development GO:0060538 48 0.037
Mouse
regulation of antimicrobial peptide production GO:0002784 44 0.037
insulin receptor signaling pathway GO:0008286 25 0.037
eye development GO:0001654 323 0.037
multicellular organism growth GO:0035264 46 0.037
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.036
regulation of cell cycle GO:0051726 291 0.036
Yeast Rat
regulation of cellular amide metabolic process GO:0034248 39 0.036
ion transport GO:0006811 145 0.036
regulation of macroautophagy GO:0016241 15 0.036
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.036
cell proliferation GO:0008283 299 0.036
response to inorganic substance GO:0010035 44 0.035
regulation of intracellular protein transport GO:0033157 46 0.034
Mouse
lipid metabolic process GO:0006629 121 0.034
Mouse
response to reactive oxygen species GO:0000302 24 0.034
negative regulation of phosphate metabolic process GO:0045936 45 0.034
Fly
protein complex biogenesis GO:0070271 201 0.034
positive regulation of apoptotic signaling pathway GO:2001235 4 0.034
wing disc morphogenesis GO:0007472 344 0.034
negative regulation of transferase activity GO:0051348 18 0.034
Fly
negative regulation of defense response GO:0031348 35 0.033
tissue migration GO:0090130 155 0.033
Fly
positive regulation of developmental growth GO:0048639 62 0.033
protein targeting GO:0006605 64 0.032
Mouse
regulation of hydrolase activity GO:0051336 97 0.032
organic cyclic compound catabolic process GO:1901361 168 0.032
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.032
regulation of nucleocytoplasmic transport GO:0046822 35 0.032
Mouse
regulation of protein transport GO:0051223 57 0.032
Mouse
macroautophagy GO:0016236 42 0.031
regulation of canonical wnt signaling pathway GO:0060828 15 0.031
Mouse
negative regulation of gene expression GO:0010629 387 0.031
protein maturation GO:0051604 71 0.031
reproductive system development GO:0061458 74 0.031
Worm Fly
positive regulation of cell death GO:0010942 69 0.031
protein targeting to nucleus GO:0044744 51 0.030
Mouse
positive regulation of cell motility GO:2000147 3 0.030
larval development GO:0002164 104 0.030
Worm
cellular carbohydrate metabolic process GO:0044262 22 0.030
establishment of organelle localization GO:0051656 122 0.029
chromatin modification GO:0016568 147 0.029
transmembrane transport GO:0055085 139 0.029
dorsal ventral pattern formation GO:0009953 133 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
ribonucleoside triphosphate metabolic process GO:0009199 119 0.028
organelle assembly GO:0070925 198 0.028
response to salt stress GO:0009651 11 0.028
response to wounding GO:0009611 94 0.027
Mouse Fly
circulatory system process GO:0003013 37 0.027
positive regulation of cellular protein metabolic process GO:0032270 118 0.027
salivary gland development GO:0007431 162 0.027
regulation of defense response to virus by host GO:0050691 10 0.027
protein processing GO:0016485 68 0.027
positive regulation of antibacterial peptide production GO:0002803 20 0.027
germ line stem cell maintenance GO:0030718 50 0.027
positive regulation of molecular function GO:0044093 136 0.027
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.027
Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.026
peptidyl amino acid modification GO:0018193 105 0.026
Human Mouse Worm
phenol containing compound metabolic process GO:0018958 57 0.026
Fly
protein complex assembly GO:0006461 200 0.026
adult chitin containing cuticle pigmentation GO:0048085 16 0.026
protein phosphorylation GO:0006468 169 0.026
single organism carbohydrate metabolic process GO:0044723 72 0.025
Mouse
cellular component assembly involved in morphogenesis GO:0010927 151 0.025
Yeast Fly
antimicrobial humoral response GO:0019730 99 0.025
Fly
ion homeostasis GO:0050801 55 0.025
specification of symmetry GO:0009799 13 0.025
Fly
regulation of nervous system development GO:0051960 248 0.025
retina development in camera type eye GO:0060041 4 0.025
positive regulation of transferase activity GO:0051347 26 0.025
negative regulation of protein metabolic process GO:0051248 85 0.024
Fly
regulation of antibacterial peptide production GO:0002786 22 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
developmental cell growth GO:0048588 52 0.024
Fly
regulation of protein serine threonine kinase activity GO:0071900 25 0.024
Fly
axon development GO:0061564 297 0.024
Fly
regulation of purine nucleotide catabolic process GO:0033121 48 0.024
carbohydrate metabolic process GO:0005975 82 0.023
Mouse
cellular response to peptide hormone stimulus GO:0071375 28 0.023
synapse organization GO:0050808 196 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
nucleoside catabolic process GO:0009164 112 0.023
cell division GO:0051301 248 0.023
cellular response to biotic stimulus GO:0071216 4 0.023
Human Mouse
carbohydrate derivative biosynthetic process GO:1901137 85 0.023
inositol lipid mediated signaling GO:0048017 4 0.022
aromatic compound catabolic process GO:0019439 166 0.022
chromatin organization GO:0006325 207 0.022
regulation of developmental pigmentation GO:0048070 24 0.022
modification dependent protein catabolic process GO:0019941 78 0.022
small gtpase mediated signal transduction GO:0007264 88 0.022
positive regulation of nucleotide metabolic process GO:0045981 55 0.022
positive regulation of innate immune response GO:0045089 38 0.022
dna metabolic process GO:0006259 227 0.022
Yeast
defense response to gram positive bacterium GO:0050830 41 0.022
Worm
histone modification GO:0016570 106 0.022
positive regulation of immune system process GO:0002684 68 0.021
Mouse
regulation of cellular ketone metabolic process GO:0010565 3 0.021
regulation of heart contraction GO:0008016 21 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
regulation of humoral immune response GO:0002920 51 0.021
Fly
protein transport GO:0015031 155 0.021
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.021
Worm Fly
positive regulation of multicellular organism growth GO:0040018 21 0.021
positive regulation of mapk cascade GO:0043410 63 0.021
skeletal muscle fiber development GO:0048741 3 0.021
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
negative regulation of cellular biosynthetic process GO:0031327 277 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.020
Fly
regulation of organ morphogenesis GO:2000027 78 0.020
secondary metabolic process GO:0019748 75 0.020
Fly
regulation of terminal button organization GO:2000331 11 0.020
regulation of synapse organization GO:0050807 110 0.020
negative regulation of nervous system development GO:0051961 92 0.020
maintenance of location GO:0051235 73 0.020
metal ion homeostasis GO:0055065 44 0.020
cell adhesion GO:0007155 136 0.020
protein heterooligomerization GO:0051291 4 0.019
skeletal muscle tissue development GO:0007519 13 0.019
Mouse
organophosphate biosynthetic process GO:0090407 46 0.019
dna integrity checkpoint GO:0031570 81 0.019
Mouse
body morphogenesis GO:0010171 2 0.019
gland development GO:0048732 191 0.019
positive regulation of defense response to virus by host GO:0002230 10 0.019
response to abiotic stimulus GO:0009628 341 0.019
striated muscle tissue development GO:0014706 27 0.019
Mouse
cell cycle arrest GO:0007050 4 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.019
negative regulation of response to external stimulus GO:0032102 22 0.019
Fly
rna processing GO:0006396 147 0.018
gtp catabolic process GO:0006184 72 0.018
positive regulation of jun kinase activity GO:0043507 4 0.018
forebrain development GO:0030900 2 0.018
negative regulation of innate immune response GO:0045824 30 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
Human Mouse
positive regulation of kinase activity GO:0033674 25 0.018
epithelial cell migration GO:0010631 148 0.018
Fly
regulation of mitochondrial fusion GO:0010635 5 0.018
cell type specific apoptotic process GO:0097285 38 0.018
cellular amine metabolic process GO:0044106 12 0.017
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.017
developmental programmed cell death GO:0010623 138 0.017
cellular hyperosmotic response GO:0071474 1 0.017
stem cell maintenance GO:0019827 67 0.017
response to alcohol GO:0097305 95 0.017
positive regulation of cell differentiation GO:0045597 64 0.017
Mouse
cellular response to lipid GO:0071396 20 0.017
Human Mouse
sensory organ morphogenesis GO:0090596 260 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.016
organelle localization GO:0051640 148 0.016
fatty acid catabolic process GO:0009062 9 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
sprouting of injured axon GO:0048682 3 0.016
Fly
muscle tissue development GO:0060537 30 0.016
Mouse
regulation of nucleotide catabolic process GO:0030811 48 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.016
negative regulation of growth GO:0045926 84 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
Yeast Mouse Worm
nucleoside phosphate biosynthetic process GO:1901293 34 0.016
axon regeneration GO:0031103 8 0.016
Fly
oxidation reduction process GO:0055114 123 0.016
Mouse
microtubule based transport GO:0010970 42 0.016
embryonic morphogenesis GO:0048598 206 0.016
Fly
response to growth factor GO:0070848 31 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
positive regulation of growth GO:0045927 75 0.016
negative regulation of cell proliferation GO:0008285 69 0.015
determination of digestive tract left right asymmetry GO:0071907 6 0.015
Fly
compound eye development GO:0048749 307 0.015
imaginal disc fusion thorax closure GO:0046529 19 0.015
Fly
phosphatidylinositol mediated signaling GO:0048015 4 0.015
regulation of mitochondrial fission GO:0090140 7 0.015
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.015
Mouse
positive regulation of apoptotic process GO:0043065 47 0.015
central nervous system development GO:0007417 201 0.015
age dependent general metabolic decline GO:0007571 3 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
regulation of protein localization to nucleus GO:1900180 29 0.015
Mouse Worm
negative regulation of response to biotic stimulus GO:0002832 12 0.015
Fly
negative regulation of biosynthetic process GO:0009890 277 0.014
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.014
purine containing compound biosynthetic process GO:0072522 30 0.014
striated muscle cell differentiation GO:0051146 90 0.014
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.014
muscle contraction GO:0006936 13 0.014

p38b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.055
bone disease DOID:0080001 0 0.031
musculoskeletal system disease DOID:17 0 0.031
connective tissue disease DOID:65 0 0.031
disease of cellular proliferation DOID:14566 0 0.028
cancer DOID:162 0 0.014
organ system cancer DOID:0050686 0 0.014
motor neuron disease DOID:231 0 0.014
central nervous system disease DOID:331 0 0.014
neurodegenerative disease DOID:1289 0 0.014