IMP

Process View

Drosophila melanogaster

38 genes annotated in fly

positive regulation of innate immune response

Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of innate immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of innate immune response" (in gray)

Name	Description	Probability	Func Analog Organism
PGRP-LC	Peptidoglycan recognition protein LC	0.298
Rel	Relish	0.186
SPE	Spatzle-Processing Enzyme	0.152	Fly
Spn27A	Serpin 27A	0.123
AttA	Attacin-A	0.121	Fly
PGRP-SA	Peptidoglycan recognition protein SA	0.104	Fly
PGRP-SD	CG7496 gene product from transcript CG7496-RA	0.095	Fly
Mtk	Metchnikowin	0.089
Dredd	Death related ced-3/Nedd2-like protein	0.089
DptB	Diptericin B	0.088	Fly
Spn28D	Serpin 28D	0.086
grass	Gram-positive Specific Serine protease	0.079	Fly
key	kenny	0.062
imd	immune deficiency	0.054
modSP	modular serine protease	0.052
pzg	putzig	0.046
Toll-6	CG7250 gene product from transcript CG7250-RA	0.044	Human Mouse
CG18666	CG18666 gene product from transcript CG18666-RA	0.043
Sp7	Serine protease 7	0.035
spz	spatzle	0.034
CG18067	CG18067 gene product from transcript CG18067-RA	0.034
LIMK1	LIM-kinase1	0.033
Duox	Dual oxidase	0.033
Trx-2	thioredoxin-2	0.033
beta'Cop	beta'-coatomer protein	0.032
gho	ghost	0.032
CG16836	CG16836 gene product from transcript CG16836-RA	0.032
Atg1	Autophagy-specific gene 1	0.030
dome	domeless	0.030
whd	withered	0.030
IM1	Immune induced molecule 1	0.029
pan	pangolin	0.029
PGRP-SC1a	CG14746 gene product from transcript CG14746-RA	0.029	Human Fly
IM10	Immune induced molecule 10	0.028
Toll-7	CG8595 gene product from transcript CG8595-RA	0.027	Human
CG15917	CG15917 gene product from transcript CG15917-RA	0.027
PGRP-SB1	CG9681 gene product from transcript CG9681-RA	0.027	Fly
bnl	branchless	0.026
rev7	CG2948 gene product from transcript CG2948-RA	0.026
Spn1	Serine protease inhibitor 1	0.026
Mcr	Macroglobulin complement-related	0.025
Mpk2	CG5475 gene product from transcript CG5475-RB	0.025
CG15065	CG15065 gene product from transcript CG15065-RA	0.025
NijA	Ninjurin A	0.024
Timp	Tissue inhibitor of metalloproteases	0.024
CG4968	CG4968 gene product from transcript CG4968-RA	0.023
IM2	Immune induced molecule 2	0.023
Hcf	Host cell factor	0.023
BG4	CG12297 gene product from transcript CG12297-RA	0.023
Myd88	CG2078 gene product from transcript CG2078-RA	0.023	Zebrafish Mouse
ird5	immune response deficient 5	0.022
AttC	Attacin-C	0.022	Fly
RpII15	RNA polymerase II 15kD subunit	0.022
bowl	brother of odd with entrails limited	0.022
CG16713	CG16713 gene product from transcript CG16713-RA	0.022
slow	slowdown	0.022
p38b	CG7393 gene product from transcript CG7393-RA	0.022
Nrx-IV	Neurexin IV	0.021
Drs	Drosomycin	0.021
PGRP-LB	Peptidoglycan recognition protein LB	0.021	Fly
Krn	Keren	0.020
upd3	unpaired 3	0.020
Cat	Catalase	0.020
Dro	Drosocin	0.020
stumps	CG31317 gene product from transcript CG31317-RC	0.020
upd2	unpaired 2	0.020
grh	grainy head	0.019
CG12424	CG12424 gene product from transcript CG12424-RC	0.019
PGRP-SC1b	CG8577 gene product from transcript CG8577-RA	0.019	Human Fly
CecC	Cecropin C	0.019
CG9184	CG9184 gene product from transcript CG9184-RB	0.019
nudC	CG9710 gene product from transcript CG9710-RA	0.019
CG12766	CG12766 gene product from transcript CG12766-RA	0.019
CG15067	CG15067 gene product from transcript CG15067-RA	0.018
pirk	poor Imd response upon knock-in	0.018
egg	eggless	0.018
Indy	I'm not dead yet	0.018
CG13422	CG13422 gene product from transcript CG13422-RA	0.018	Fly
AGO2	Argonaute 2	0.017
Mekk1	CG7717 gene product from transcript CG7717-RB	0.017
CG9139	CG9139 gene product from transcript CG9139-RA	0.017
piwi	CG6122 gene product from transcript CG6122-RA	0.017	Fly
fon	fondue	0.017
grn	grain	0.017
Plap	Phospholipase A2 activator protein	0.017
CG5791	CG5791 gene product from transcript CG5791-RA	0.016
Vps16A	Vacuolar protein sorting 16A	0.016
Cf2	Chorion factor 2	0.016
verm	vermiform	0.016
IM4	Immune induced molecule 4	0.016
RASSF8	CG5053 gene product from transcript CG5053-RA	0.016
CG16718	CG16718 gene product from transcript CG16718-RA	0.016
pck	pickel	0.016
CG32185	CG32185 gene product from transcript CG32185-RA	0.016
CG5778	CG5778 gene product from transcript CG5778-RB	0.015
Idgf2	Imaginal disc growth factor 2	0.015
CHORD	CG6198 gene product from transcript CG6198-RA	0.015
Irc	Immune-regulated catalase	0.015
eater	CG6124 gene product from transcript CG6124-RB	0.015
CG13901	CG13901 gene product from transcript CG13901-RA	0.015
Dlic	Dynein light intermediate chain	0.015
bbg	big bang	0.015
Spn88Eb	Serpin 88Eb	0.015
IM23	Immune induced molecule 23	0.014
Cyp6a13	CG2397 gene product from transcript CG2397-RA	0.014
Dpt	Diptericin	0.014
CG9372	CG9372 gene product from transcript CG9372-RA	0.014
CG30156	CG30156 gene product from transcript CG30156-RA	0.014
Hr96	Hormone receptor-like in 96	0.014
Glt	Glutactin	0.013
psh	persephone	0.013
RpII215	RNA polymerase II 215kD subunit	0.013
Reg-5	Rhythmically expressed gene 5	0.013
Cctgamma	CG8977 gene product from transcript CG8977-RC	0.013
I-2	Inhibitor-2	0.013
Tak1	TGF-beta activated kinase 1	0.013
Gadd45	CG11086 gene product from transcript CG11086-RA	0.013
E(var)3-9	Enhancer of variegation 3-9	0.013
CG18594	CG18594 gene product from transcript CG18594-RA	0.013
CG42369	CG42369 gene product from transcript CG42369-RA	0.013
JIL-1	CG6297 gene product from transcript CG6297-RA	0.013
kug	kugelei	0.013
Rac2	CG8556 gene product from transcript CG8556-RA	0.013
Hnf4	Hepatocyte nuclear factor 4	0.013
CG8258	CG8258 gene product from transcript CG8258-RA	0.013
TepIII	Thiolester containing protein III	0.012
sinu	sinuous	0.012
CG8586	CG8586 gene product from transcript CG8586-RA	0.012
CG13323	CG13323 gene product from transcript CG13323-RA	0.012
knk	knickkopf	0.012
HLH106	Helix loop helix protein 106	0.012
GNBP1	Gram-negative bacteria binding protein 1	0.012
mael	maelstrom	0.012
nec	necrotic	0.012
Cont	Contactin	0.012
Oli	Olig family	0.012
spirit	Serine Protease Immune Response Integrator	0.012
18w	18 wheeler	0.012	Human Mouse
lace	CG4162 gene product from transcript CG4162-RA	0.012
CG6361	CG6361 gene product from transcript CG6361-RA	0.012
l(2)05510	lethal (2) 05510	0.012
CG8128	CG8128 gene product from transcript CG8128-RA	0.012
CalpA	Calpain-A	0.012
Gp93	Glycoprotein 93	0.012
GNBP3	Gram-negative bacteria binding protein 3	0.012	Fly
Cap-H2	Chromosome associated protein H2	0.012
fs(1)Yb	female sterile (1) Yb	0.012
SuUR	Suppressor of Under-Replication	0.012
Tl	Toll	0.012	Mouse
Lis-1	Lissencephaly-1	0.012
CG42863	CG42863 gene product from transcript CG42863-RB	0.012
nxf2	nuclear RNA export factor 2	0.012
CG31743	CG31743 gene product from transcript CG31743-RA	0.012
sr	stripe	0.012
jing	CG9397 gene product from transcript CG9397-RI	0.011
CG13962	CG13962 gene product from transcript CG13962-RA	0.011
GckIII	Germinal centre kinase III	0.011
CG6426	CG6426 gene product from transcript CG6426-RA	0.011
Pvr	PDGF- and VEGF-receptor related	0.011
Hs6st	Heparan sulfate 6-O-sulfotransferase	0.011
conv	convoluted	0.011
Pvf2	PDGF- and VEGF-related factor 2	0.011
CG5390	CG5390 gene product from transcript CG5390-RA	0.011
form3	formin 3	0.011
wun	wunen	0.011
lok	loki	0.011
blot	bloated tubules	0.011
CG4730	CG4730 gene product from transcript CG4730-RA	0.011
He	Hemese	0.011
lig	lingerer	0.011
stwl	stonewall	0.011
Sir2	CG5216 gene product from transcript CG5216-RA	0.011
pie	pineapple eye	0.011
Ing3	CG6632 gene product from transcript CG6632-RA	0.011
A2bp1	Ataxin-2 binding protein 1	0.011
TER94	CG2331 gene product from transcript CG2331-RA	0.011
SpdS	Spermidine Synthase	0.011
Parg	Poly(ADP-ribose) glycohydrolase	0.011
chrb	charybde	0.011
RpS10a	Ribosomal protein S10a	0.011
luna	CG33473 gene product from transcript CG33473-RB	0.011
CG31646	CG31646 gene product from transcript CG31646-RA	0.011
Hsf	Heat shock factor	0.011
etaTry	etaTrypsin	0.011
CecA2	Cecropin A2	0.011
Rab2	Rab-protein 2	0.011
CG40127	CG40127 gene product from transcript CG40127-RA	0.011
mRpS10	mitochondrial ribosomal protein S10	0.011
CG8202	CG8202 gene product from transcript CG8202-RA	0.011
CG9989	CG9989 gene product from transcript CG9989-RA	0.011
Traf6	TNF-receptor-associated factor 6	0.011
sfl	sulfateless	0.011
Gr28b	Gustatory receptor 28b	0.011
CG10026	CG10026 gene product from transcript CG10026-RA	0.010
MP1	Melanization Protease 1	0.010	Fly
CG10969	CG10969 gene product from transcript CG10969-RA	0.010
TORC	CG6064 gene product from transcript CG6064-RA	0.010
alphaCop	alpha-coatomer protein	0.010
TM9SF4	CG7364 gene product from transcript CG7364-RA	0.010
tub	tube	0.010
spn-E	spindle E	0.010
Rpn1	CG7762 gene product from transcript CG7762-RA	0.010
Fs(2)Ket	Female sterile (2) Ketel	0.010
CG13482	CG13482 gene product from transcript CG13482-RA	0.010
CG18769	CG18769 gene product from transcript CG18769-RB	0.010
Snap24	Synapse protein 24	0.010
sug	sugarbabe	0.010
Rbp6	RNA-binding protein 6	0.010
Eip71CD	Ecdysone-induced protein 28/29kD	0.010
Nc	Nedd2-like caspase	0.010	Fly
CG33470	CG33470 gene product from transcript CG33470-RA	0.010