|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
1 |
1.000
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
1 |
1.000
|
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
26 |
1.000
|
|
|
|
germ line stem cell division
|
GO:0042078 |
25 |
1.000
|
|
|
|
regulation of synaptic growth at neuromuscular junction
|
GO:0008582 |
89 |
1.000
|
|
|
|
synaptic growth at neuromuscular junction
|
GO:0051124 |
119 |
1.000
|
|
|
|
anterior posterior pattern specification imaginal disc
|
GO:0007448 |
16 |
1.000
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
3 |
1.000
|
|
|
|
synapse organization
|
GO:0050808 |
196 |
1.000
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
149 |
1.000
|
|
|
|
wing disc anterior posterior pattern formation
|
GO:0048100 |
5 |
1.000
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
248 |
1.000
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
4 |
1.000
|
Fly |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
6 |
1.000
|
Fly |
|
|
negative regulation of cellular macromolecule biosynthetic process
|
GO:2000113 |
267 |
0.999
|
Zebrafish |
|
|
growth
|
GO:0040007 |
359 |
0.999
|
|
|
|
germ line stem cell maintenance
|
GO:0030718 |
50 |
0.999
|
|
|
|
cell cell signaling involved in cell fate commitment
|
GO:0045168 |
210 |
0.999
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
1 |
0.999
|
|
|
|
heart development
|
GO:0007507 |
82 |
0.999
|
Zebrafish Mouse |
|
|
synaptic transmission
|
GO:0007268 |
288 |
0.999
|
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.999
|
Mouse |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
16 |
0.998
|
|
|
|
regulation of synapse assembly
|
GO:0051963 |
94 |
0.998
|
|
|
|
developmental growth
|
GO:0048589 |
280 |
0.998
|
|
|
|
negative regulation of nucleobase containing compound metabolic process
|
GO:0045934 |
261 |
0.998
|
Zebrafish |
|
|
negative regulation of cellular biosynthetic process
|
GO:0031327 |
277 |
0.998
|
Zebrafish |
|
|
cell elongation involved in imaginal disc derived wing morphogenesis
|
GO:0090254 |
5 |
0.998
|
Fly |
|
|
tube development
|
GO:0035295 |
244 |
0.998
|
|
|
|
synapse assembly
|
GO:0007416 |
143 |
0.997
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
201 |
0.997
|
|
|
|
heart morphogenesis
|
GO:0003007 |
32 |
0.997
|
Zebrafish |
|
|
stem cell development
|
GO:0048864 |
79 |
0.997
|
|
|
|
single organism intracellular transport
|
GO:1902582 |
207 |
0.997
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
6 |
0.996
|
Fly |
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.996
|
|
|
|
negative regulation of rna biosynthetic process
|
GO:1902679 |
240 |
0.996
|
Zebrafish |
|
|
chemotaxis
|
GO:0006935 |
249 |
0.996
|
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.996
|
Zebrafish |
|
|
negative regulation of cellular metabolic process
|
GO:0031324 |
382 |
0.996
|
Zebrafish Fly |
|
|
regulation of synapse organization
|
GO:0050807 |
110 |
0.996
|
|
|
|
negative regulation of synaptic growth at neuromuscular junction
|
GO:0045886 |
39 |
0.996
|
Fly |
|
|
immune response
|
GO:0006955 |
246 |
0.995
|
|
|
|
negative regulation of autophagy
|
GO:0010507 |
16 |
0.995
|
Fly |
|
|
regulation of growth
|
GO:0040008 |
233 |
0.995
|
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.995
|
Zebrafish |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
142 |
0.994
|
Fly |
|
|
malpighian tubule development
|
GO:0072002 |
64 |
0.994
|
|
|
|
gland development
|
GO:0048732 |
191 |
0.993
|
|
|
|
circulatory system development
|
GO:0072359 |
82 |
0.993
|
Zebrafish Mouse |
|
|
negative regulation of response to stimulus
|
GO:0048585 |
258 |
0.993
|
Fly |
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.992
|
|
|
|
protein modification process
|
GO:0036211 |
438 |
0.991
|
Mouse |
|
|
cell proliferation
|
GO:0008283 |
299 |
0.991
|
Mouse Fly |
|
|
histone modification
|
GO:0016570 |
106 |
0.991
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.991
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.990
|
|
|
|
histoblast morphogenesis
|
GO:0007488 |
9 |
0.990
|
|
|
|
tube morphogenesis
|
GO:0035239 |
191 |
0.990
|
|
|
|
endodermal cell fate commitment
|
GO:0001711 |
3 |
0.989
|
|
|
|
developmental growth involved in morphogenesis
|
GO:0060560 |
65 |
0.989
|
Fly |
|
|
somatic stem cell maintenance
|
GO:0035019 |
14 |
0.989
|
|
|
|
cardiovascular system development
|
GO:0072358 |
82 |
0.989
|
Zebrafish Mouse |
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.989
|
|
|
|
protein localization
|
GO:0008104 |
284 |
0.987
|
|
|
|
eye antennal disc development
|
GO:0035214 |
60 |
0.986
|
Fly |
|
|
epithelial tube morphogenesis
|
GO:0060562 |
88 |
0.985
|
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.985
|
|
|
|
taxis
|
GO:0042330 |
304 |
0.985
|
|
|
|
hindgut development
|
GO:0061525 |
58 |
0.984
|
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.984
|
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.982
|
|
|
|
protein import into nucleus
|
GO:0006606 |
51 |
0.980
|
|
|
|
protein phosphorylation
|
GO:0006468 |
169 |
0.980
|
Mouse |
|
|
endoderm formation
|
GO:0001706 |
3 |
0.979
|
|
|
|
axon development
|
GO:0061564 |
297 |
0.979
|
Fly |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
143 |
0.979
|
|
|
|
regulation of cell development
|
GO:0060284 |
215 |
0.978
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
26 |
0.976
|
|
|
|
regulation of protein transport
|
GO:0051223 |
57 |
0.975
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
201 |
0.974
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
302 |
0.974
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
13 |
0.973
|
Fly |
|
|
imaginal disc derived appendage morphogenesis
|
GO:0035114 |
395 |
0.973
|
|
|
|
cell fate specification
|
GO:0001708 |
71 |
0.972
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.971
|
|
|
|
gliogenesis
|
GO:0042063 |
80 |
0.970
|
|
|
|
cellular macromolecule localization
|
GO:0070727 |
220 |
0.970
|
|
|
|
ovarian follicle cell development
|
GO:0030707 |
248 |
0.969
|
|
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.969
|
Mouse Fly |
|
|
positive regulation of growth
|
GO:0045927 |
75 |
0.968
|
|
|
|
muscle structure development
|
GO:0061061 |
224 |
0.967
|
Fly |
|
|
imaginal disc derived wing vein morphogenesis
|
GO:0008586 |
44 |
0.966
|
|
|
|
positive regulation of developmental growth
|
GO:0048639 |
62 |
0.966
|
|
|
|
lateral inhibition
|
GO:0046331 |
206 |
0.966
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
92 |
0.966
|
Fly |
|
|
connective tissue development
|
GO:0061448 |
3 |
0.965
|
Mouse |
|
|
epithelial cell migration
|
GO:0010631 |
148 |
0.964
|
|
|
|
sensory organ morphogenesis
|
GO:0090596 |
260 |
0.963
|
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.961
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
23 |
0.961
|
|
|
|
kidney epithelium development
|
GO:0072073 |
3 |
0.961
|
Mouse |
|
|
imaginal disc derived wing morphogenesis
|
GO:0007476 |
337 |
0.960
|
|
|
|
male gamete generation
|
GO:0048232 |
201 |
0.960
|
|
|
|
regulation of cell growth
|
GO:0001558 |
43 |
0.959
|
|
|
|
imaginal disc derived appendage development
|
GO:0048737 |
399 |
0.959
|
|
|
|
organ growth
|
GO:0035265 |
56 |
0.959
|
Mouse |
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.959
|
|
|
|
axonogenesis
|
GO:0007409 |
290 |
0.959
|
Fly |
|
|
negative regulation of gene expression
|
GO:0010629 |
387 |
0.958
|
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.958
|
|
|
|
regulation of organ growth
|
GO:0046620 |
42 |
0.958
|
|
|
|
stem cell maintenance
|
GO:0019827 |
67 |
0.956
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
158 |
0.956
|
|
|
|
negative regulation of signal transduction
|
GO:0009968 |
206 |
0.956
|
Fly |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
18 |
0.954
|
Fly |
|
|
muscle organ development
|
GO:0007517 |
127 |
0.954
|
Fly |
|
|
stem cell division
|
GO:0017145 |
69 |
0.953
|
|
|
|
eye antennal disc morphogenesis
|
GO:0007455 |
34 |
0.950
|
|
|
|
glial cell differentiation
|
GO:0010001 |
35 |
0.949
|
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.947
|
|
|
|
negative regulation of signaling
|
GO:0023057 |
219 |
0.947
|
Fly |
|
|
regulation of autophagy
|
GO:0010506 |
62 |
0.946
|
Fly |
|
|
intracellular transport
|
GO:0046907 |
228 |
0.946
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
46 |
0.944
|
|
|
|
protein complex biogenesis
|
GO:0070271 |
201 |
0.943
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
80 |
0.942
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
90 |
0.941
|
|
|
|
cognition
|
GO:0050890 |
141 |
0.941
|
|
|
|
positive regulation of rna metabolic process
|
GO:0051254 |
271 |
0.939
|
|
|
|
negative regulation of nucleic acid templated transcription
|
GO:1903507 |
240 |
0.939
|
Zebrafish |
|
|
regulation of imaginal disc growth
|
GO:0045570 |
26 |
0.939
|
|
|
|
hindbrain development
|
GO:0030902 |
2 |
0.937
|
Mouse |
|
|
spermatogenesis
|
GO:0007283 |
200 |
0.936
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
276 |
0.936
|
|
|
|
chromatin modification
|
GO:0016568 |
147 |
0.935
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
29 |
0.935
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
51 |
0.935
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
163 |
0.933
|
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.933
|
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.933
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.932
|
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.931
|
Mouse Fly |
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.930
|
|
|
|
regulation of protein phosphorylation
|
GO:0001932 |
64 |
0.929
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
45 |
0.928
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
63 |
0.928
|
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.928
|
|
|
|
regionalization
|
GO:0003002 |
416 |
0.926
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
55 |
0.923
|
|
|
|
peptidyl amino acid modification
|
GO:0018193 |
105 |
0.922
|
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.921
|
|
|
|
enteroendocrine cell differentiation
|
GO:0035883 |
1 |
0.920
|
|
|
|
organic substance transport
|
GO:0071702 |
257 |
0.917
|
|
|
|
single organism cellular localization
|
GO:1902580 |
180 |
0.915
|
|
|
|
protein localization to organelle
|
GO:0033365 |
82 |
0.914
|
|
|
|
morphogenesis of a branching epithelium
|
GO:0061138 |
45 |
0.910
|
|
|
|
regulation of cell size
|
GO:0008361 |
63 |
0.909
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
4 |
0.908
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
67 |
0.907
|
|
|
|
regulation of phosphorylation
|
GO:0042325 |
147 |
0.906
|
Fly |
|
|
protein transport
|
GO:0015031 |
155 |
0.904
|
|
|
|
negative regulation of rna metabolic process
|
GO:0051253 |
251 |
0.904
|
Zebrafish |
|
|
chorion containing eggshell formation
|
GO:0007304 |
105 |
0.904
|
|
|
|
negative regulation of macromolecule biosynthetic process
|
GO:0010558 |
270 |
0.904
|
Zebrafish |
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
12 |
0.902
|
Fly |
|
|
negative regulation of transcription dna templated
|
GO:0045892 |
237 |
0.902
|
Zebrafish |
|
|
branching involved in open tracheal system development
|
GO:0060446 |
45 |
0.900
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
341 |
0.900
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
130 |
0.899
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
37 |
0.898
|
|
|
|
embryonic development via the syncytial blastoderm
|
GO:0001700 |
148 |
0.898
|
|
|
|
cellular protein localization
|
GO:0034613 |
160 |
0.898
|
|
|
|
eggshell formation
|
GO:0030703 |
105 |
0.898
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
5 |
0.894
|
|
|
|
axon guidance
|
GO:0007411 |
233 |
0.891
|
Fly |
|
|
regulation of phosphate metabolic process
|
GO:0019220 |
210 |
0.891
|
Fly |
|
|
determination of adult lifespan
|
GO:0008340 |
137 |
0.890
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
242 |
0.889
|
Zebrafish Fly |
|
|
morphogenesis of a branching structure
|
GO:0001763 |
45 |
0.886
|
|
|
|
renal system development
|
GO:0072001 |
72 |
0.885
|
|
|
|
embryonic hindgut morphogenesis
|
GO:0048619 |
48 |
0.884
|
|
|
|
primary branching open tracheal system
|
GO:0007428 |
6 |
0.884
|
|
|
|
formation of anatomical boundary
|
GO:0048859 |
37 |
0.882
|
|
|
|
regulation of catabolic process
|
GO:0009894 |
170 |
0.881
|
Fly |
|
|
regulation of phosphorus metabolic process
|
GO:0051174 |
210 |
0.878
|
Fly |
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
13 |
0.878
|
Fly |
|
|
single organism nuclear import
|
GO:1902593 |
51 |
0.875
|
|
|
|
mesoderm development
|
GO:0007498 |
78 |
0.867
|
Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
51 |
0.866
|
|
|
|
imaginal disc growth
|
GO:0007446 |
37 |
0.859
|
|
|
|
organic acid metabolic process
|
GO:0006082 |
103 |
0.859
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
69 |
0.857
|
|
|
|
intracellular protein transport
|
GO:0006886 |
104 |
0.857
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
11 |
0.852
|
|
|
|
response to radiation
|
GO:0009314 |
155 |
0.849
|
|
|
|
compound eye morphogenesis
|
GO:0001745 |
249 |
0.840
|
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.840
|
|
|
|
respiratory system development
|
GO:0060541 |
213 |
0.839
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
61 |
0.839
|
|
|
|
localization of cell
|
GO:0051674 |
257 |
0.837
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
9 |
0.835
|
Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.832
|
|
|
|
central nervous system development
|
GO:0007417 |
201 |
0.831
|
Mouse Fly |
|
|
single organism catabolic process
|
GO:0044712 |
228 |
0.830
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
256 |
0.828
|
|
|
|
cell motility
|
GO:0048870 |
251 |
0.828
|
|
|
|
regulation of immune response
|
GO:0050776 |
118 |
0.828
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
15 |
0.827
|
|
|
|
oxoacid metabolic process
|
GO:0043436 |
103 |
0.825
|
|
|
|
renal tubule morphogenesis
|
GO:0061333 |
44 |
0.825
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
10 |
0.824
|
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
157 |
0.824
|
Fly |
|
|
nuclear transport
|
GO:0051169 |
72 |
0.822
|
|
|
|
post embryonic appendage morphogenesis
|
GO:0035120 |
385 |
0.817
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
140 |
0.813
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
119 |
0.812
|
|
|
|
response to organic substance
|
GO:0010033 |
284 |
0.812
|
|
|
|
defense response to bacterium
|
GO:0042742 |
178 |
0.812
|
|
|
|
positive regulation of signal transduction
|
GO:0009967 |
223 |
0.809
|
|
|
|
nuclear import
|
GO:0051170 |
51 |
0.806
|
|
|
|
male meiosis
|
GO:0007140 |
52 |
0.796
|
|
|
|
positive regulation of protein localization to plasma membrane
|
GO:1903078 |
3 |
0.795
|
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.794
|
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.794
|
|
|
|
regulation of epithelial cell differentiation
|
GO:0030856 |
4 |
0.789
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
83 |
0.787
|
|
|
|
regulation of protein modification process
|
GO:0031399 |
112 |
0.787
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
15 |
0.786
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
140 |
0.786
|
Fly |
|
|
formation of primary germ layer
|
GO:0001704 |
24 |
0.785
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
74 |
0.785
|
|
|
|
neuron projection guidance
|
GO:0097485 |
241 |
0.784
|
Fly |
|
|
protein complex assembly
|
GO:0006461 |
200 |
0.784
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
0 |
0.779
|
|
|
|
multicellular organism growth
|
GO:0035264 |
46 |
0.777
|
Worm |
|
|
appendage development
|
GO:0048736 |
401 |
0.777
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
103 |
0.776
|
|
|
|
regulation of cell proliferation
|
GO:0042127 |
163 |
0.776
|
Mouse Fly |
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.775
|
|
|
|
hindgut morphogenesis
|
GO:0007442 |
58 |
0.774
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
206 |
0.773
|
|
|
|
digestive tract development
|
GO:0048565 |
149 |
0.770
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
109 |
0.769
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
119 |
0.766
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
98 |
0.766
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
69 |
0.765
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
84 |
0.758
|
Fly |
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
1 |
0.753
|
|
|
|
cellular response to insulin stimulus
|
GO:0032869 |
28 |
0.753
|
|
|
|
response to growth factor
|
GO:0070848 |
31 |
0.752
|
|
|
|
appendage morphogenesis
|
GO:0035107 |
397 |
0.751
|
|
|
|
autophagy
|
GO:0006914 |
108 |
0.748
|
Fly |
|
|
anterior malpighian tubule development
|
GO:0061327 |
12 |
0.742
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
2 |
0.739
|
|
|
|
unidimensional cell growth
|
GO:0009826 |
15 |
0.739
|
Fly |
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.738
|
|
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.732
|
|
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.732
|
Fly |
|
|
embryonic organ development
|
GO:0048568 |
50 |
0.730
|
Zebrafish |
|
|
wing disc morphogenesis
|
GO:0007472 |
344 |
0.729
|
|
|
|
larval development
|
GO:0002164 |
104 |
0.729
|
Fly |
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.724
|
|
|
|
response to nutrient levels
|
GO:0031667 |
114 |
0.723
|
|
|
|
positive regulation of multicellular organismal process
|
GO:0051240 |
143 |
0.722
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
61 |
0.722
|
|
|
|
regulation of synapse structure and activity
|
GO:0050803 |
128 |
0.721
|
|
|
|
response to light stimulus
|
GO:0009416 |
124 |
0.716
|
|
|
|
forebrain development
|
GO:0030900 |
2 |
0.713
|
|
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.711
|
Human |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
3 |
0.710
|
|
|
|
carboxylic acid metabolic process
|
GO:0019752 |
92 |
0.708
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
47 |
0.708
|
|
|
|
brain development
|
GO:0007420 |
120 |
0.706
|
Mouse Fly |
|
|
aging
|
GO:0007568 |
143 |
0.704
|
Fly |
|
|
response to fungus
|
GO:0009620 |
50 |
0.702
|
|
|
|
nephron epithelium development
|
GO:0072009 |
3 |
0.701
|
|
|
|
biological adhesion
|
GO:0022610 |
138 |
0.697
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
62 |
0.694
|
|
|
|
heterocycle catabolic process
|
GO:0046700 |
166 |
0.689
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
143 |
0.689
|
|
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.683
|
|
|
|
response to endogenous stimulus
|
GO:0009719 |
119 |
0.681
|
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.680
|
|
|
|
establishment of protein localization
|
GO:0045184 |
163 |
0.679
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
130 |
0.678
|
|
|
|
regulation of protein localization
|
GO:0032880 |
76 |
0.678
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
1 |
0.675
|
|
|
|
head development
|
GO:0060322 |
135 |
0.675
|
Mouse Fly |
|
|
covalent chromatin modification
|
GO:0016569 |
106 |
0.674
|
|
|
|
death
|
GO:0016265 |
284 |
0.674
|
|
|
|
endoderm development
|
GO:0007492 |
6 |
0.673
|
|
|
|
tissue migration
|
GO:0090130 |
155 |
0.672
|
|
|
|
genital disc development
|
GO:0035215 |
44 |
0.671
|
|
|
|
body morphogenesis
|
GO:0010171 |
2 |
0.671
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.670
|
|
|
|
regulation of intracellular signal transduction
|
GO:1902531 |
236 |
0.669
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
108 |
0.669
|
Fly |
|
|
cell rearrangement involved in malpighian tubule morphogenesis
|
GO:0061334 |
3 |
0.660
|
|
|
|
positive regulation of response to stimulus
|
GO:0048584 |
323 |
0.660
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
47 |
0.659
|
|
|
|
spermatid development
|
GO:0007286 |
98 |
0.655
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
9 |
0.652
|
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
155 |
0.652
|
|
|
|
cuticle development
|
GO:0042335 |
86 |
0.646
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
6 |
0.644
|
|
|
|
cell growth
|
GO:0016049 |
108 |
0.642
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
92 |
0.640
|
|
|
|
cell proliferation involved in imaginal disc derived wing morphogenesis
|
GO:0090255 |
2 |
0.639
|
Fly |
|
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.639
|
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.635
|
|
|
|
muscle tissue development
|
GO:0060537 |
30 |
0.632
|
Mouse |
|
|
negative regulation of synapse assembly
|
GO:0051964 |
39 |
0.631
|
Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
50 |
0.630
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
34 |
0.627
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
81 |
0.624
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
17 |
0.618
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
53 |
0.614
|
|
|
|
protein targeting
|
GO:0006605 |
64 |
0.612
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.609
|
|
|
|
regulation of synaptic transmission
|
GO:0050804 |
69 |
0.606
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
18 |
0.602
|
|
|
|
defense response to other organism
|
GO:0098542 |
225 |
0.601
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
17 |
0.600
|
|
|
|
positive regulation of muscle organ development
|
GO:0048636 |
6 |
0.599
|
|
|
|
open tracheal system development
|
GO:0007424 |
204 |
0.593
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
52 |
0.592
|
|
|
|
amine metabolic process
|
GO:0009308 |
12 |
0.578
|
|
|
|
embryonic heart tube development
|
GO:0035050 |
22 |
0.575
|
Zebrafish |
|
|
catabolic process
|
GO:0009056 |
409 |
0.572
|
Fly |
|
|
eye development
|
GO:0001654 |
323 |
0.570
|
|
|
|
renal tubule development
|
GO:0061326 |
64 |
0.570
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
72 |
0.566
|
|
|
|
positive regulation of signaling
|
GO:0023056 |
243 |
0.565
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
12 |
0.565
|
|
|
|
single organism behavior
|
GO:0044708 |
391 |
0.564
|
|
|
|
stem cell differentiation
|
GO:0048863 |
117 |
0.562
|
|
|
|
regulation of establishment of protein localization to plasma membrane
|
GO:0090003 |
7 |
0.560
|
|
|
|
cell death
|
GO:0008219 |
279 |
0.559
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
85 |
0.559
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
34 |
0.555
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
18 |
0.552
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
30 |
0.545
|
|
|
|
regulation of cellular localization
|
GO:0060341 |
136 |
0.545
|
|
|
|
positive regulation of phosphate metabolic process
|
GO:0045937 |
139 |
0.543
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
64 |
0.540
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
62 |
0.538
|
|
|
|
multi organism behavior
|
GO:0051705 |
175 |
0.537
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
122 |
0.536
|
|
|
|
cell fate determination
|
GO:0001709 |
91 |
0.534
|
|
|
|
cell adhesion
|
GO:0007155 |
136 |
0.534
|
|
|
|
epithelium migration
|
GO:0090132 |
148 |
0.533
|
|
|
|
membrane organization
|
GO:0061024 |
112 |
0.531
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
69 |
0.526
|
|
|
|
heart field specification
|
GO:0003128 |
0 |
0.520
|
|
|
|
neural precursor cell proliferation
|
GO:0061351 |
75 |
0.520
|
|
|
|
dorsal closure
|
GO:0007391 |
79 |
0.520
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
9 |
0.516
|
|
|
|
skeletal muscle organ development
|
GO:0060538 |
48 |
0.511
|
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.508
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
47 |
0.498
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
55 |
0.497
|
|
|
|
locomotory behavior
|
GO:0007626 |
176 |
0.497
|
|
|
|
sex differentiation
|
GO:0007548 |
81 |
0.489
|
Worm |
|
|
nephron tubule development
|
GO:0072080 |
3 |
0.489
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
64 |
0.487
|
Mouse |
|
|
positive regulation of protein modification process
|
GO:0031401 |
58 |
0.487
|
|
|
|
regulation of protein localization to plasma membrane
|
GO:1903076 |
7 |
0.486
|
|
|
|
nephron development
|
GO:0072006 |
3 |
0.483
|
|
|
|
imaginal disc pattern formation
|
GO:0007447 |
91 |
0.477
|
|
|
|
myotube cell development
|
GO:0014904 |
3 |
0.472
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
14 |
0.469
|
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.465
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
109 |
0.459
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
105 |
0.458
|
|
|
|
cardioblast differentiation
|
GO:0010002 |
20 |
0.455
|
|
|
|
compound eye development
|
GO:0048749 |
307 |
0.454
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
3 |
0.452
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
85 |
0.451
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
116 |
0.449
|
|
|
|
cell migration
|
GO:0016477 |
238 |
0.449
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
87 |
0.448
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
293 |
0.448
|
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
145 |
0.439
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
72 |
0.439
|
|
|
|
positive regulation of phosphorus metabolic process
|
GO:0010562 |
139 |
0.435
|
|
|
|
neurological system process
|
GO:0050877 |
358 |
0.435
|
|
|
|
apoptotic process involved in development
|
GO:1902742 |
20 |
0.432
|
|
|
|
epithelial cell development
|
GO:0002064 |
274 |
0.431
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
27 |
0.430
|
|
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.430
|
|
|
|
negative regulation of developmental growth
|
GO:0048640 |
64 |
0.429
|
Fly |
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.428
|
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.427
|
|
|
|
axis specification
|
GO:0009798 |
167 |
0.426
|
Fly |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
45 |
0.421
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
59 |
0.417
|
|
|
|
stem cell proliferation
|
GO:0072089 |
88 |
0.416
|
|
|
|
protein import
|
GO:0017038 |
55 |
0.415
|
|
|
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.414
|
|
|
|
positive regulation of intracellular signal transduction
|
GO:1902533 |
116 |
0.411
|
|
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
12 |
0.409
|
|
|
|
purine nucleoside metabolic process
|
GO:0042278 |
127 |
0.408
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
116 |
0.407
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
53 |
0.402
|
|
|
|
insulin receptor signaling pathway
|
GO:0008286 |
25 |
0.401
|
|
|
|
columnar cuboidal epithelial cell development
|
GO:0002066 |
249 |
0.401
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
58 |
0.395
|
|
|
|
positive regulation of transport
|
GO:0051050 |
92 |
0.394
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
19 |
0.393
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
21 |
0.393
|
|
|
|
regulation of transport
|
GO:0051049 |
181 |
0.391
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
130 |
0.390
|
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
165 |
0.389
|
|
|
|
positive regulation of synapse assembly
|
GO:0051965 |
29 |
0.388
|
|
|
|
cell competition in a multicellular organism
|
GO:0035212 |
10 |
0.386
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
38 |
0.386
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
79 |
0.385
|
|
|
|
defense response to gram negative bacterium
|
GO:0050829 |
94 |
0.382
|
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.381
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
109 |
0.373
|
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
217 |
0.370
|
|
|
|
epidermal cell differentiation
|
GO:0009913 |
51 |
0.370
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
31 |
0.369
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
131 |
0.367
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
136 |
0.365
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
12 |
0.364
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
145 |
0.364
|
|
|
|
establishment of vesicle localization
|
GO:0051650 |
51 |
0.361
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
29 |
0.360
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
88 |
0.360
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
65 |
0.360
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
80 |
0.357
|
|
|
|
innate immune response
|
GO:0045087 |
144 |
0.353
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
119 |
0.349
|
|
|
|
lipid metabolic process
|
GO:0006629 |
121 |
0.348
|
|
|
|
negative regulation of molecular function
|
GO:0044092 |
51 |
0.347
|
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
165 |
0.346
|
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
106 |
0.343
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
28 |
0.342
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
38 |
0.341
|
Zebrafish Fly |
|
|
feeding behavior
|
GO:0007631 |
50 |
0.335
|
|
|
|
smad protein import into nucleus
|
GO:0007184 |
11 |
0.334
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
71 |
0.334
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
90 |
0.332
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
115 |
0.331
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
200 |
0.329
|
|
|
|
digestive system development
|
GO:0055123 |
149 |
0.329
|
|
|
|
chromosome organization
|
GO:0051276 |
360 |
0.328
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
108 |
0.325
|
|
|
|
nephron tubule morphogenesis
|
GO:0072078 |
3 |
0.323
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
12 |
0.318
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
24 |
0.315
|
|
|
|
positive regulation of cell communication
|
GO:0010647 |
250 |
0.315
|
|
|
|
response to peptide hormone
|
GO:0043434 |
29 |
0.312
|
|
|
|
response to starvation
|
GO:0042594 |
97 |
0.309
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
79 |
0.307
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
297 |
0.306
|
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
127 |
0.305
|
|
|
|
stress fiber assembly
|
GO:0043149 |
6 |
0.304
|
|
|
|
multi organism reproductive behavior
|
GO:0044705 |
121 |
0.303
|
|
|
|
positive regulation of epithelial cell differentiation
|
GO:0030858 |
1 |
0.302
|
|
|
|
mushroom body development
|
GO:0016319 |
70 |
0.300
|
Fly |
|
|
nephron epithelium morphogenesis
|
GO:0072088 |
3 |
0.300
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
145 |
0.300
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
322 |
0.299
|
|
|
|
positive regulation of establishment of protein localization to plasma membrane
|
GO:0090004 |
3 |
0.298
|
|
|
|
decapentaplegic signaling pathway
|
GO:0008101 |
19 |
0.298
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
112 |
0.297
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
52 |
0.296
|
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
145 |
0.295
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
103 |
0.293
|
|
|
|
mapk cascade
|
GO:0000165 |
107 |
0.292
|
Mouse |
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.292
|
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.288
|
|
|
|
defense response
|
GO:0006952 |
300 |
0.288
|
Mouse |
|
|
organ formation
|
GO:0048645 |
39 |
0.286
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
116 |
0.282
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
112 |
0.282
|
|
|
|
negative regulation of cell communication
|
GO:0010648 |
223 |
0.282
|
Fly |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
163 |
0.281
|
|
|
|
regulation of cell fate commitment
|
GO:0010453 |
29 |
0.277
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
61 |
0.276
|
|
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.276
|
|
|
|
regulation of translation
|
GO:0006417 |
56 |
0.275
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
74 |
0.273
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
25 |
0.272
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
294 |
0.269
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
1 |
0.267
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
16 |
0.263
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
40 |
0.262
|
Worm |
|
|
learning or memory
|
GO:0007611 |
141 |
0.261
|
|
|
|
cell division
|
GO:0051301 |
248 |
0.257
|
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
166 |
0.256
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
83 |
0.256
|
|
