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Process View

Drosophila melanogaster

14 genes annotated in fly

somatic stem cell maintenance

Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "somatic stem cell maintenance"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "somatic stem cell maintenance" (in gray)

Name	Description	Probability	Func Analog Organism
Mad	Mothers against dpp	0.989
emc	extra macrochaetae	0.708
osa	CG7467 gene product from transcript CG7467-RD	0.589
rap	retina aberrant in pattern	0.524
fz2	frizzled 2	0.414
pnr	pannier	0.411
Dad	Daughters against dpp	0.384	Fly
ci	cubitus interruptus	0.373
shn	schnurri	0.371
gro	groucho	0.312
Egfr	Epidermal growth factor receptor	0.311
E(spl)	Enhancer of split	0.299
yki	yorkie	0.239	Mouse
l(2)gl	lethal (2) giant larvae	0.230
aop	anterior open	0.194
N	Notch	0.185	Zebrafish
Tsc1	CG6147 gene product from transcript CG6147-RA	0.156
da	daughterless	0.149
gcm	glial cells missing	0.144
tld	tolloid	0.130
mbc	myoblast city	0.119
eya	eyes absent	0.114
Med	Medea	0.112
smo	smoothened	0.107
hth	homothorax	0.105
dsh	dishevelled	0.097
kni	knirps	0.092
fz	frizzled	0.085
bowl	brother of odd with entrails limited	0.078
Sin3A	CG8815 gene product from transcript CG8815-RC	0.077
m2	E(spl) region transcript m2	0.077
malpha	E(spl) region transcript malpha	0.076
Abd-B	Abdominal B	0.073
brat	brain tumor	0.070
lin	lines	0.070
neur	neuralized	0.068
vvl	ventral veins lacking	0.067
tll	tailless	0.060
ush	u-shaped	0.056
amos	absent MD neurons and olfactory sensilla	0.056
stg	string	0.055
gig	gigas	0.054
ato	atonal	0.047
sens	senseless	0.047
HLHmgamma	E(spl) region transcript mgamma	0.046
hpo	hippo	0.046
stumps	CG31317 gene product from transcript CG31317-RC	0.044
insc	inscuteable	0.044
spdo	sanpodo	0.043
sna	snail	0.042
tkv	thickveins	0.042
ft	fat	0.039
Su(H)	Suppressor of Hairless	0.039	Mouse
ap	apterous	0.038
pyd	polychaetoid	0.038
ed	echinoid	0.037
dm	diminutive	0.037
Su(z)12	CG8013 gene product from transcript CG8013-RA	0.036
hrg	hiiragi	0.034
hh	hedgehog	0.034
Ser	Serrate	0.032
brm	brahma	0.032
ds	dachsous	0.032
HLHm5	E(spl) region transcript m5	0.031
ebi	CG4063 gene product from transcript CG4063-RA	0.031
HLHm7	E(spl) region transcript m7	0.030
ssh	slingshot	0.030
babo	baboon	0.030
tup	tailup	0.029
fng	fringe	0.029
sca	scabrous	0.029
klu	klumpfuss	0.028
Btk29A	Btk family kinase at 29A	0.027
dpn	deadpan	0.025	Mouse
ro	rough	0.025
ewg	erect wing	0.024
put	punt	0.024
Rab11	Rab-protein 11	0.024
arr	arrow	0.024	Mouse
Myd88	CG2078 gene product from transcript CG2078-RA	0.023
sbb	scribbler	0.023
bnl	branchless	0.022
Dl	Delta	0.022
HLHmbeta	E(spl) region transcript mbeta	0.022
Ras85D	Ras oncogene at 85D	0.022
Sce	Sex combs extra	0.021
dock	dreadlocks	0.021
dome	domeless	0.021
slp1	sloppy paired 1	0.020
sd	scalloped	0.020
sr	stripe	0.020
os	outstretched	0.020
hbs	hibris	0.020
Cdk4	Cyclin-dependent kinase 4	0.019
dy	dusky	0.019
swa	swallow	0.019
CadN	Cadherin-N	0.019	Fly
opa	odd paired	0.018
crb	crumbs	0.018
nmo	nemo	0.018
stan	starry night	0.018
numb	CG3779 gene product from transcript CG3779-RB	0.017
G-oalpha47A	G protein oalpha 47A	0.017
Tom	Twin of m4	0.017
wg	wingless	0.016
sax	saxophone	0.016
rib	ribbon	0.016
crp	cropped	0.016
wts	warts	0.016
NetB	Netrin-B	0.015
CG9063	CG9063 gene product from transcript CG9063-RA	0.015
sog	short gastrulation	0.015
sev	sevenless	0.014
HLHmdelta	E(spl) region transcript mdelta	0.014
ac	achaete	0.014	Mouse
dpp	decapentaplegic	0.014
rhea	CG6831 gene product from transcript CG6831-RA	0.014
Wnk	CG7177 gene product from transcript CG7177-RA	0.014
sc	scute	0.013	Mouse
ems	empty spiracles	0.013
pasha	partner of drosha	0.013
NFAT	NFAT homolog	0.013
gogo	golden goal	0.013
bam	bag of marbles	0.013
MED19	Mediator complex subunit 19	0.013
e(y)3	enhancer of yellow 3	0.013
Xe7	CG2179 gene product from transcript CG2179-RA	0.013
Mkk4	MAP kinase kinase 4	0.013
run	runt	0.013
Fas3	Fasciclin 3	0.013
shot	short stop	0.013
ena	enabled	0.013
Wnt4	Wnt oncogene analog 4	0.012	Mouse
retn	retained	0.012
esg	escargot	0.012
pygo	pygopus	0.012
Rel	Relish	0.012
ptc	patched	0.012
pon	partner of numb	0.012
Notum	CG13076 gene product from transcript CG13076-RB	0.012
wb	wing blister	0.012
repo	reversed polarity	0.011
swm	second mitotic wave missing	0.011
Gef26	CG9491 gene product from transcript CG9491-RB	0.011
eff	effete	0.011
drpr	draper	0.011
nkd	naked cuticle	0.011
ase	asense	0.011	Mouse
Eip75B	Ecdysone-induced protein 75B	0.011
eve	even skipped	0.010
kn	knot	0.010
Ubx	Ultrabithorax	0.010
CtBP	C-terminal Binding Protein	0.010
bib	big brain	0.010
mirr	mirror	0.010
Pvr	PDGF- and VEGF-receptor related	0.010
en	engrailed	0.010
Wnt5	Wnt oncogene analog 5	0.010
blot	bloated tubules	0.010