Drosophila melanogaster

61 known processes

unc-5 (Dmel_CG8166)

CG8166 gene product from transcript CG8166-RA

(Aliases: UNC5,CT20824,Unc5,UNC-5,Unc-5,UNC5D,Dunc5,Unc5d,CG8168,AAF7419,CG8166,unc5,Dmel\CG8166)

unc-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axon development GO:0061564 297 0.999
axonogenesis GO:0007409 290 0.998
regulation of axon guidance GO:1902667 10 0.994
axon midline choice point recognition GO:0016199 26 0.994
regulation of axon extension involved in axon guidance GO:0048841 4 0.990
axon guidance GO:0007411 233 0.988
motor neuron axon guidance GO:0008045 58 0.987
chemotaxis GO:0006935 249 0.981
neuron projection guidance GO:0097485 241 0.975
photoreceptor cell axon guidance GO:0072499 23 0.959
axon choice point recognition GO:0016198 26 0.955
taxis GO:0042330 304 0.947
dendrite guidance GO:0070983 21 0.928
regulation of cell development GO:0060284 215 0.922
Mouse Worm
olfactory bulb axon guidance GO:0071678 3 0.908
axon extension involved in axon guidance GO:0048846 10 0.893
regulation of neurogenesis GO:0050767 158 0.881
Mouse Worm
retinal ganglion cell axon guidance GO:0031290 12 0.768
regulation of cell differentiation GO:0045595 302 0.698
Mouse Worm
negative regulation of neurogenesis GO:0050768 53 0.691
cell motility GO:0048870 251 0.679
localization of cell GO:0051674 257 0.671
neuron recognition GO:0008038 101 0.670
regulation of behavior GO:0050795 75 0.573
cell migration GO:0016477 238 0.557
regulation of nervous system development GO:0051960 248 0.551
Mouse Worm
eye photoreceptor cell differentiation GO:0001754 145 0.510
regulation of photoreceptor cell axon guidance GO:2000289 5 0.497
tube development GO:0035295 244 0.494
Zebrafish Worm
central nervous system development GO:0007417 201 0.473
Mouse
cell recognition GO:0008037 102 0.471
regulation of multicellular organismal development GO:2000026 414 0.465
Zebrafish Mouse Worm
cellular protein modification process GO:0006464 438 0.449
telencephalon development GO:0021537 2 0.439
compound eye photoreceptor cell differentiation GO:0001751 140 0.421
regionalization GO:0003002 416 0.417
axon extension GO:0048675 32 0.404
Worm
developmental growth involved in morphogenesis GO:0060560 65 0.394
Worm
dendrite development GO:0016358 204 0.393
Worm
regulation of cellular component movement GO:0051270 42 0.380
Mouse
salivary gland development GO:0007431 162 0.379
regulation of chemotaxis GO:0050920 12 0.374
eye development GO:0001654 323 0.369
negative regulation of axon extension GO:0030517 3 0.355
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.342
tissue migration GO:0090130 155 0.339
Worm
tissue morphogenesis GO:0048729 297 0.332
Zebrafish Worm
neuron projection extension GO:1990138 32 0.327
Worm
regulation of cell morphogenesis GO:0022604 163 0.327
Worm
developmental cell growth GO:0048588 52 0.322
Worm
gliogenesis GO:0042063 80 0.318
gland development GO:0048732 191 0.310
forebrain development GO:0030900 2 0.310
synapse assembly GO:0007416 143 0.307
eye photoreceptor cell development GO:0042462 81 0.305
eye morphogenesis GO:0048592 260 0.294
formation of anatomical boundary GO:0048859 37 0.294
regulation of cell projection organization GO:0031344 92 0.289
Worm
regulation of axonogenesis GO:0050770 32 0.288
Worm
photoreceptor cell differentiation GO:0046530 170 0.275
neuron fate commitment GO:0048663 50 0.272
cell adhesion GO:0007155 136 0.266
axon target recognition GO:0007412 16 0.258
regulation of phosphorylation GO:0042325 147 0.240
positive regulation of cellular component organization GO:0051130 156 0.233
Worm
negative regulation of nervous system development GO:0051961 92 0.216
regulation of neuron differentiation GO:0045664 103 0.215
Worm
biological adhesion GO:0022610 138 0.213
negative regulation of rna biosynthetic process GO:1902679 240 0.213
protein modification process GO:0036211 438 0.205
head development GO:0060322 135 0.202
Mouse
regulation of anatomical structure size GO:0090066 163 0.200
Worm
regulation of localization GO:0032879 275 0.199
Mouse
photoreceptor cell development GO:0042461 96 0.199
homeostatic process GO:0042592 199 0.196
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.195
sensory organ morphogenesis GO:0090596 260 0.185
establishment of localization in cell GO:0051649 402 0.184
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.183
compound eye photoreceptor development GO:0042051 78 0.180
negative regulation of cell communication GO:0010648 223 0.179
Human
negative regulation of developmental growth GO:0048640 64 0.178
regulation of developmental growth GO:0048638 174 0.170
Worm
positive regulation of rna biosynthetic process GO:1902680 266 0.169
compound eye photoreceptor fate commitment GO:0001752 36 0.166
positive regulation of cell communication GO:0010647 250 0.165
Human Rat
r7 cell differentiation GO:0045466 43 0.164
locomotory behavior GO:0007626 176 0.164
regulation of cell growth GO:0001558 43 0.162
Worm
epithelial tube morphogenesis GO:0060562 88 0.159
Zebrafish
positive regulation of cellular biosynthetic process GO:0031328 316 0.156
exocrine system development GO:0035272 162 0.154
regulation of molecular function GO:0065009 217 0.149
negative regulation of multicellular organismal process GO:0051241 142 0.147
Zebrafish
positive regulation of nervous system development GO:0051962 69 0.147
Worm
regulation of neuron projection development GO:0010975 69 0.147
Worm
synaptic target recognition GO:0008039 45 0.146
ion transport GO:0006811 145 0.144
embryonic pattern specification GO:0009880 174 0.144
cognition GO:0050890 141 0.142
axonal defasciculation GO:0007414 12 0.141
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.139
metal ion transport GO:0030001 74 0.138
negative regulation of growth GO:0045926 84 0.137
compound eye development GO:0048749 307 0.136
positive regulation of transcription dna templated GO:0045893 266 0.136
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.134
dorsal ventral axon guidance GO:0033563 2 0.131
Worm
rhythmic process GO:0048511 106 0.129
muscle structure development GO:0061061 224 0.129
tube morphogenesis GO:0035239 191 0.128
Zebrafish Worm
dendrite morphogenesis GO:0048813 199 0.127
circadian rhythm GO:0007623 105 0.126
cation transport GO:0006812 110 0.125
developmental growth GO:0048589 280 0.124
Worm
positive regulation of axonogenesis GO:0050772 2 0.121
Worm
negative regulation of signaling GO:0023057 219 0.117
Human
positive regulation of gene expression GO:0010628 290 0.116
regulation of cell death GO:0010941 173 0.115
Human Mouse Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.112
Worm
spinal cord development GO:0021510 1 0.112
ameboidal type cell migration GO:0001667 151 0.112
Worm
compound eye morphogenesis GO:0001745 249 0.111
growth GO:0040007 359 0.110
Worm
regulation of axon extension GO:0030516 8 0.110
Worm
positive regulation of macromolecule metabolic process GO:0010604 405 0.109
central nervous system projection neuron axonogenesis GO:0021952 6 0.106
intracellular signal transduction GO:0035556 300 0.103
Human
small molecule metabolic process GO:0044281 305 0.102
synapse organization GO:0050808 196 0.100
regulation of intracellular signal transduction GO:1902531 236 0.098
Human
rhythmic behavior GO:0007622 76 0.094
negative regulation of cell differentiation GO:0045596 143 0.094
positive regulation of phosphorus metabolic process GO:0010562 139 0.093
cell proliferation GO:0008283 299 0.093
neuronal stem cell division GO:0036445 35 0.091
positive regulation of biosynthetic process GO:0009891 316 0.091
negative regulation of gene expression GO:0010629 387 0.088
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.087
death GO:0016265 284 0.085
Human Mouse Rat
gland morphogenesis GO:0022612 145 0.084
programmed cell death GO:0012501 257 0.084
Human Mouse Rat
positive regulation of protein metabolic process GO:0051247 128 0.083
organ formation GO:0048645 39 0.083
regulation of protein metabolic process GO:0051246 256 0.082
ras protein signal transduction GO:0007265 88 0.081
negative regulation of cell development GO:0010721 62 0.080
positive regulation of nucleic acid templated transcription GO:1903508 266 0.080
salivary gland morphogenesis GO:0007435 145 0.079
chemosensory behavior GO:0007635 106 0.079
convergent extension GO:0060026 2 0.078
brain development GO:0007420 120 0.078
Mouse
regulation of cell size GO:0008361 63 0.076
Worm
eye photoreceptor cell fate commitment GO:0042706 37 0.074
wnt signaling pathway GO:0016055 98 0.074
substrate dependent cell migration GO:0006929 3 0.074
macromolecule catabolic process GO:0009057 161 0.073
Worm
protein catabolic process GO:0030163 101 0.073
Worm
glial cell migration GO:0008347 31 0.072
ventral cord development GO:0007419 16 0.072
cell fate determination GO:0001709 91 0.071
positive regulation of intracellular signal transduction GO:1902533 116 0.071
Human
stem cell fate commitment GO:0048865 25 0.071
appendage development GO:0048736 401 0.071
regulation of cell proliferation GO:0042127 163 0.071
cell cell adhesion GO:0098609 26 0.070
salivary gland boundary specification GO:0007432 8 0.070
positive regulation of signal transduction GO:0009967 223 0.070
Human Rat
epithelial cell differentiation GO:0030855 322 0.070
detection of abiotic stimulus GO:0009582 66 0.069
kidney epithelium development GO:0072073 3 0.067
neuroepithelial cell differentiation GO:0060563 6 0.067
neuroblast proliferation GO:0007405 74 0.067
regulation of cell substrate adhesion GO:0010810 2 0.066
positive regulation of signaling GO:0023056 243 0.065
Human Rat
single organism behavior GO:0044708 391 0.065
proteolysis GO:0006508 192 0.064
divalent inorganic cation transport GO:0072511 30 0.064
formation of organ boundary GO:0010160 30 0.063
immune system process GO:0002376 347 0.062
purine containing compound metabolic process GO:0072521 155 0.062
negative regulation of response to stimulus GO:0048585 258 0.061
Human
regulation of cellular component size GO:0032535 98 0.060
Worm
positive regulation of phosphate metabolic process GO:0045937 139 0.060
regulation of neural precursor cell proliferation GO:2000177 35 0.059
dna metabolic process GO:0006259 227 0.059
small gtpase mediated signal transduction GO:0007264 88 0.059
positive regulation of cell development GO:0010720 61 0.058
Worm
organic substance catabolic process GO:1901575 308 0.058
Worm
gene silencing GO:0016458 138 0.058
anterior commissure morphogenesis GO:0021960 2 0.057
macromolecular complex assembly GO:0065003 256 0.057
cell junction organization GO:0034330 57 0.056
regulation of synapse assembly GO:0051963 94 0.055
kidney development GO:0001822 3 0.055
positive regulation of rna metabolic process GO:0051254 271 0.054
detection of stimulus GO:0051606 156 0.054
hematopoietic progenitor cell differentiation GO:0002244 1 0.054
apoptotic process GO:0006915 159 0.052
Human Mouse Rat
positive regulation of response to stimulus GO:0048584 323 0.052
Human Rat
positive regulation of cell differentiation GO:0045597 64 0.051
Worm
protein complex assembly GO:0006461 200 0.051
detection of stimulus involved in sensory perception GO:0050906 92 0.050
negative regulation of signal transduction GO:0009968 206 0.050
Human
olfactory learning GO:0008355 56 0.050
cell growth GO:0016049 108 0.049
Worm
positive regulation of axon guidance GO:1902669 1 0.049
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.049
response to abiotic stimulus GO:0009628 341 0.049
cellular homeostasis GO:0019725 80 0.049
positive regulation of developmental process GO:0051094 143 0.049
Worm
gastrulation involving germ band extension GO:0010004 36 0.048
r7 cell fate commitment GO:0007465 12 0.048
negative regulation of cellular biosynthetic process GO:0031327 277 0.048
photoreceptor cell fate commitment GO:0046552 41 0.048
single organism cellular localization GO:1902580 180 0.048
regulation of growth GO:0040008 233 0.047
Worm
skin development GO:0043588 65 0.047
positive regulation of cellular protein metabolic process GO:0032270 118 0.046
somatic stem cell division GO:0048103 37 0.046
organonitrogen compound metabolic process GO:1901564 318 0.045
negative regulation of synapse assembly GO:0051964 39 0.045
regulation of cellular component biogenesis GO:0044087 201 0.045
regulation of extent of cell growth GO:0061387 8 0.044
Worm
negative regulation of chemotaxis GO:0050922 1 0.043
morphogenesis of a branching epithelium GO:0061138 45 0.043
Zebrafish
epithelium migration GO:0090132 148 0.043
regulation of phosphorus metabolic process GO:0051174 210 0.043
stem cell differentiation GO:0048863 117 0.042
long term memory GO:0007616 62 0.042
regulation of rac protein signal transduction GO:0035020 3 0.042
regulation of apoptotic process GO:0042981 130 0.041
Human Mouse Rat
regulation of anatomical structure morphogenesis GO:0022603 242 0.041
Zebrafish Worm
neural precursor cell proliferation GO:0061351 75 0.040
regulation of photoreceptor cell differentiation GO:0046532 34 0.040
ventral furrow formation GO:0007370 17 0.039
single organism biosynthetic process GO:0044711 206 0.039
cation transmembrane transport GO:0098655 88 0.039
respiratory system development GO:0060541 213 0.039
oxoacid metabolic process GO:0043436 103 0.039
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.039
stem cell development GO:0048864 79 0.039
rac protein signal transduction GO:0016601 3 0.039
epithelial cell migration GO:0010631 148 0.038
neuron migration GO:0001764 5 0.038
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.038
response to external biotic stimulus GO:0043207 293 0.038
carbohydrate derivative metabolic process GO:1901135 217 0.038
morphogenesis of an epithelium GO:0002009 276 0.038
Zebrafish
embryonic organ development GO:0048568 50 0.037
regulation of catalytic activity GO:0050790 185 0.037
negative regulation of nucleic acid templated transcription GO:1903507 240 0.037
negative regulation of neuron differentiation GO:0045665 16 0.036
neuroblast differentiation GO:0014016 29 0.036
gastrulation GO:0007369 70 0.036
Worm
epithelial cell development GO:0002064 274 0.036
lateral inhibition GO:0046331 206 0.036
reproductive behavior GO:0019098 122 0.035
chromatin organization GO:0006325 207 0.035
imaginal disc derived wing morphogenesis GO:0007476 337 0.035
defasciculation of motor neuron axon GO:0007415 8 0.035
negative regulation of rna metabolic process GO:0051253 251 0.034
extrinsic apoptotic signaling pathway GO:0097191 1 0.034
Human Rat
chaeta development GO:0022416 97 0.034
pigmentation GO:0043473 75 0.034
post embryonic appendage morphogenesis GO:0035120 385 0.034
regulation of mapk cascade GO:0043408 92 0.034
open tracheal system development GO:0007424 204 0.033
vesicle mediated transport GO:0016192 381 0.033
single organism intracellular transport GO:1902582 207 0.033
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.032
Worm
digestive tract morphogenesis GO:0048546 127 0.032
Worm
cytoplasmic transport GO:0016482 130 0.032
cell death GO:0008219 279 0.032
Human Mouse Rat
cellular response to chemical stimulus GO:0070887 199 0.032
epidermis development GO:0008544 65 0.031
endocytosis GO:0006897 310 0.031
negative regulation of cellular metabolic process GO:0031324 382 0.031
regulation of circadian rhythm GO:0042752 49 0.031
central nervous system neuron differentiation GO:0021953 8 0.030
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
positive regulation of molecular function GO:0044093 136 0.030
regulation of phosphate metabolic process GO:0019220 210 0.030
glial cell development GO:0021782 27 0.030
regulation of canonical wnt signaling pathway GO:0060828 15 0.030
circadian behavior GO:0048512 76 0.029
response to other organism GO:0051707 293 0.029
regulation of protein modification process GO:0031399 112 0.029
blastoderm segmentation GO:0007350 159 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.029
negative regulation of transcription dna templated GO:0045892 237 0.028
response to organic substance GO:0010033 284 0.028
positive regulation of cellular component biogenesis GO:0044089 80 0.028
catabolic process GO:0009056 409 0.027
Worm
secretion GO:0046903 109 0.027
regulation of epithelial cell migration GO:0010632 12 0.027
cardiovascular system development GO:0072358 82 0.027
Zebrafish
single organism cell adhesion GO:0098602 47 0.026
regulation of proteolysis GO:0030162 87 0.026
germ cell migration GO:0008354 43 0.026
determination of bilateral symmetry GO:0009855 13 0.026
muscle organ development GO:0007517 127 0.026
positive regulation of cell motility GO:2000147 3 0.026
organelle fission GO:0048285 340 0.025
neuron remodeling GO:0016322 29 0.025
organic acid metabolic process GO:0006082 103 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
r7 cell development GO:0045467 14 0.025
detection of external stimulus GO:0009581 66 0.025
nuclear division GO:0000280 332 0.025
segmentation GO:0035282 207 0.025
muscle cell differentiation GO:0042692 103 0.025
cytosolic calcium ion transport GO:0060401 2 0.025
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
neurological system process GO:0050877 358 0.024
regulation of cell cycle GO:0051726 291 0.024
regulation of programmed cell death GO:0043067 152 0.024
Human Mouse Rat
imaginal disc derived appendage development GO:0048737 399 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
inositol lipid mediated signaling GO:0048017 4 0.024
Human
mapk cascade GO:0000165 107 0.024
striated muscle cell differentiation GO:0051146 90 0.024
regulation of synapse structure and activity GO:0050803 128 0.024
regulation of wnt signaling pathway GO:0030111 68 0.023
digestive system development GO:0055123 149 0.023
Worm
calcium ion transport GO:0006816 24 0.023
cardiac cell fate commitment GO:0060911 17 0.023
cardioblast differentiation GO:0010002 20 0.023
appendage morphogenesis GO:0035107 397 0.023
negative chemotaxis GO:0050919 15 0.023
axis specification GO:0009798 167 0.023
positive regulation of axon extension GO:0045773 2 0.022
Worm
response to fungus GO:0009620 50 0.022
divalent metal ion transport GO:0070838 26 0.022
wound healing GO:0042060 75 0.022
positive regulation of neurogenesis GO:0050769 41 0.022
Worm
hindbrain development GO:0030902 2 0.022
negative regulation of response to external stimulus GO:0032102 22 0.022
cellular response to abiotic stimulus GO:0071214 58 0.022
phenol containing compound metabolic process GO:0018958 57 0.022
regulation of cell adhesion GO:0030155 27 0.022
positive regulation of hydrolase activity GO:0051345 78 0.022
negative regulation of molecular function GO:0044092 51 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
negative regulation of cell death GO:0060548 81 0.021
Human
regulation of synapse organization GO:0050807 110 0.021
positive regulation of proteolysis GO:0045862 52 0.021
reproductive system development GO:0061458 74 0.021
Worm
morphogenesis of a branching structure GO:0001763 45 0.021
Zebrafish
pigment biosynthetic process GO:0046148 36 0.021
chemical homeostasis GO:0048878 92 0.021
purine nucleotide metabolic process GO:0006163 146 0.021
startle response GO:0001964 16 0.021
cell cell junction organization GO:0045216 55 0.021
gtp metabolic process GO:0046039 72 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.020
metal ion homeostasis GO:0055065 44 0.020
immune response regulating signaling pathway GO:0002764 2 0.020
intracellular transport GO:0046907 228 0.020
regulation of small gtpase mediated signal transduction GO:0051056 93 0.020
regulation of cell motility GO:2000145 23 0.020
Mouse
cell division GO:0051301 248 0.020
single organismal cell cell adhesion GO:0016337 45 0.020
purine containing compound catabolic process GO:0072523 112 0.020
homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 18 0.020
protein maturation GO:0051604 71 0.020
chromosome organization GO:0051276 360 0.020
regulation of transport GO:0051049 181 0.020
chromatin assembly GO:0031497 48 0.020
positive regulation of programmed cell death GO:0043068 62 0.020
Mouse Rat
response to biotic stimulus GO:0009607 294 0.019
regulation of cytoskeleton organization GO:0051493 89 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
negative regulation of cell proliferation GO:0008285 69 0.019
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.019
cell fate specification GO:0001708 71 0.019
regulation of phosphatase activity GO:0010921 3 0.019
glandular epithelial cell differentiation GO:0002067 1 0.019
regulation of epithelial cell differentiation GO:0030856 4 0.019
neuroblast fate determination GO:0007400 12 0.019
determination of muscle attachment site GO:0016204 7 0.019
purine ribonucleotide catabolic process GO:0009154 109 0.019
organic hydroxy compound biosynthetic process GO:1901617 21 0.018
regulation of response to external stimulus GO:0032101 115 0.018
cell migration involved in gastrulation GO:0042074 9 0.018
Worm
membrane organization GO:0061024 112 0.018
ribose phosphate metabolic process GO:0019693 145 0.018
immune system development GO:0002520 57 0.018
larval development GO:0002164 104 0.018
transmembrane transport GO:0055085 139 0.018
cell maturation GO:0048469 144 0.018
regulation of cellular localization GO:0060341 136 0.018
semaphorin plexin signaling pathway involved in regulation of photoreceptor cell axon guidance GO:2000305 2 0.018
negative regulation of apoptotic process GO:0043066 63 0.018
Human
regulation of ras protein signal transduction GO:0046578 93 0.018
dendrite self avoidance GO:0070593 8 0.018
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.018
organic substance transport GO:0071702 257 0.018
neuromuscular junction development GO:0007528 149 0.018
lamellipodium organization GO:0097581 21 0.018
regulation of cell division GO:0051302 72 0.018
neuromuscular process GO:0050905 21 0.017
hemopoiesis GO:0030097 46 0.017
entrainment of circadian clock GO:0009649 16 0.017
multicellular organismal reproductive behavior GO:0033057 110 0.017
roundabout signaling pathway GO:0035385 4 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
regulation of immune system process GO:0002682 176 0.017
body morphogenesis GO:0010171 2 0.017
retina development in camera type eye GO:0060041 4 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
regulation of hydrolase activity GO:0051336 97 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
protein localization GO:0008104 284 0.016
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.016
positive regulation of neuron differentiation GO:0045666 26 0.016
Worm
positive regulation of phosphorylation GO:0042327 87 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.016
regulation of transferase activity GO:0051338 58 0.016
purine nucleoside triphosphate metabolic process GO:0009144 119 0.016
multi organism behavior GO:0051705 175 0.016
positive regulation of cell adhesion GO:0045785 10 0.015
branching involved in open tracheal system development GO:0060446 45 0.015
anatomical structure homeostasis GO:0060249 97 0.015
cellular catabolic process GO:0044248 372 0.015
immune response activating signal transduction GO:0002757 2 0.015
embryonic morphogenesis GO:0048598 206 0.015
Worm
response to wounding GO:0009611 94 0.015
positive regulation of cell migration GO:0030335 2 0.015
positive regulation of epithelial cell differentiation GO:0030858 1 0.015
regulation of locomotion GO:0040012 42 0.015
Mouse Worm
cellular nitrogen compound catabolic process GO:0044270 165 0.015
regulation of cell shape GO:0008360 113 0.015
regulation of protein phosphorylation GO:0001932 64 0.015
hematopoietic or lymphoid organ development GO:0048534 57 0.015
cellular macromolecular complex assembly GO:0034622 153 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
cellular response to oxygen containing compound GO:1901701 79 0.014
memory GO:0007613 94 0.014
nucleoside metabolic process GO:0009116 127 0.014
dna packaging GO:0006323 91 0.014
nephron epithelium development GO:0072009 3 0.014
secretion by cell GO:0032940 101 0.014
cellular protein localization GO:0034613 160 0.014
heterocycle catabolic process GO:0046700 166 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
central nervous system neuron axonogenesis GO:0021955 7 0.014
pole plasm assembly GO:0007315 61 0.014
negative regulation of developmental process GO:0051093 201 0.014
Zebrafish
endomembrane system organization GO:0010256 119 0.014
multi organism reproductive behavior GO:0044705 121 0.013
chaeta morphogenesis GO:0008407 42 0.013
regulation of cell cell adhesion GO:0022407 21 0.013
cellular response to nitrogen compound GO:1901699 51 0.013
branching morphogenesis of an epithelial tube GO:0048754 45 0.013
Zebrafish
positive regulation of cell projection organization GO:0031346 29 0.013
Worm
glycosyl compound catabolic process GO:1901658 112 0.013
morphogenesis of a polarized epithelium GO:0001738 93 0.013
anterior posterior axis specification GO:0009948 109 0.013
cardioblast cell fate commitment GO:0042684 14 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
mitotic nuclear division GO:0007067 213 0.013
development of primary sexual characteristics GO:0045137 50 0.013
Worm
reproductive structure development GO:0048608 74 0.013
Worm
cellular protein complex assembly GO:0043623 71 0.013
oxidoreduction coenzyme metabolic process GO:0006733 2 0.013
negative regulation of homeostatic process GO:0032845 2 0.013
spermatogenesis GO:0007283 200 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
phosphorylation GO:0016310 294 0.012
glial cell differentiation GO:0010001 35 0.012
response to lipopolysaccharide GO:0032496 4 0.012
positive regulation of receptor internalization GO:0002092 2 0.012
protein complex biogenesis GO:0070271 201 0.012
oviposition GO:0018991 19 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
regulation of organelle organization GO:0033043 196 0.012
embryonic axis specification GO:0000578 107 0.012
axis elongation GO:0003401 3 0.012
positive regulation of catabolic process GO:0009896 105 0.012
nitrogen compound transport GO:0071705 85 0.012

unc-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.293
urinary system disease DOID:18 0 0.293
sensory system disease DOID:0050155 0 0.023
eye and adnexa disease DOID:1492 0 0.023
nervous system disease DOID:863 0 0.023
eye disease DOID:5614 0 0.022
cardiovascular system disease DOID:1287 0 0.013
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012
organ system cancer DOID:0050686 0 0.012