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Drosophila melanogaster

26 genes annotated in fly

axon midline choice point recognition

The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "axon midline choice point recognition"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "axon midline choice point recognition" (in gray)

Name	Description	Probability	Func Analog Organism
robo	roundabout	0.999
Rac1	CG2248 gene product from transcript CG2248-RA	0.998
trio	CG18214 gene product from transcript CG18214-RA	0.997
lola	longitudinals lacking	0.996
NetB	Netrin-B	0.994
unc-5	CG8166 gene product from transcript CG8166-RA	0.994
ena	enabled	0.989
lea	leak	0.988	Zebrafish Mouse Rat Fly
fra	frazzled	0.988
dock	dreadlocks	0.986
SoxN	SoxNeuro	0.970
comm	commissureless	0.944
Sdc	Syndecan	0.939
beta-Spec	beta Spectrin	0.925
tutl	turtle	0.840
Sema-1a	CG18405 gene product from transcript CG18405-RD	0.835
Wnt5	Wnt oncogene analog 5	0.810
robo3	CG5423 gene product from transcript CG5423-RA	0.793	Zebrafish Mouse Rat Fly
Fas2	Fasciclin 2	0.787
chic	chickadee	0.782
stumps	CG31317 gene product from transcript CG31317-RC	0.737
pod1	CG4532 gene product from transcript CG4532-RF	0.723
plexA	plexin A	0.714
G-oalpha47A	G protein oalpha 47A	0.678	Fly
sli	slit	0.645
Eph	Eph receptor tyrosine kinase	0.636
drl	derailed	0.616
mew	multiple edematous wings	0.616
Ten-m	Tenascin major	0.561
Dscam	Down syndrome cell adhesion molecule	0.550
Trim9	CG31721 gene product from transcript CG31721-RB	0.534
Nrg	Neuroglian	0.525
RhoGAPp190	CG32555 gene product from transcript CG32555-RB	0.505
Ptp69D	Protein tyrosine phosphatase 69D	0.477
Mtl	Mig-2-like	0.428	Fly
mid	midline	0.425
shot	short stop	0.420
ph-p	polyhomeotic proximal	0.404
plexB	plexin B	0.385	Fly
slp1	sloppy paired 1	0.384
otk	off-track	0.370
spi	spitz	0.336
nerfin-1	nervous fingers 1	0.299
Caps	Calcium activated protein for secretion	0.290
hipk	homeodomain interacting protein kinase	0.286
bab2	CG9102 gene product from transcript CG9102-RA	0.280	Fly
zfh1	Zn finger homeodomain 1	0.276
kuz	kuzbanian	0.268
DAAM	Dishevelled Associated Activator of Morphogenesis	0.261
l(2)k16918	lethal (2) k16918	0.257
Hem	HEM-protein	0.255
Abl	Abl tyrosine kinase	0.253
drk	downstream of receptor kinase	0.248
drpr	draper	0.243
repo	reversed polarity	0.232
stan	starry night	0.231
dnc	dunce	0.229
Ephrin	CG1862 gene product from transcript CG1862-RA	0.221
LIMK1	LIM-kinase1	0.219
vvl	ventral veins lacking	0.208
insc	inscuteable	0.206
Rac2	CG8556 gene product from transcript CG8556-RA	0.194	Fly
sqz	squeeze	0.192
nvy	nervy	0.178
Mrtf	Myocardin-related transcription factor	0.171
rok	Rho-kinase	0.161
cas	castor	0.160
Fas3	Fasciclin 3	0.159
Sema-2a	CG4700 gene product from transcript CG4700-RC	0.155	Fly
crol	crooked legs	0.155
wdb	widerborst	0.153
Atg1	Autophagy-specific gene 1	0.144
form3	formin 3	0.140
futsch	CG34387 gene product from transcript CG34387-RC	0.136
tgo	tango	0.135
JIL-1	CG6297 gene product from transcript CG6297-RA	0.134
HGTX	CG13475 gene product from transcript CG13475-RB	0.127
CadN	Cadherin-N	0.122
pdm2	POU domain protein 2	0.122
Vsx2	CG33980 gene product from transcript CG33980-RA	0.121
hkb	huckebein	0.118
elav	embryonic lethal abnormal vision	0.116
Nrx-IV	Neurexin IV	0.115
nub	nubbin	0.108
fas	faint sausage	0.108
trn	tartan	0.104
Wnt4	Wnt oncogene analog 4	0.097
salm	spalt major	0.097
tok	tolkin	0.096
LanA	Laminin A	0.095
gsb	gooseberry	0.094
tbce	tubulin-specific chaperone E	0.092
Ca-alpha1D	Ca[2+]-channel protein alpha[[1]] subunit D	0.090
rap	retina aberrant in pattern	0.090
stai	stathmin	0.087
jing	CG9397 gene product from transcript CG9397-RI	0.085
Rpn6	Proteasome p44.5 subunit	0.085
loqs	loquacious	0.084
qm	quemao	0.083
CG33960	CG33960 gene product from transcript CG33960-RB	0.083
fog	folded gastrulation	0.082
InR	Insulin-like receptor	0.080
kel	kelch	0.078
nrv2	nervana 2	0.078
hiw	highwire	0.077
glec	gliolectin	0.076
Kr	Kruppel	0.075
LanB1	CG7123 gene product from transcript CG7123-RA	0.075
Mical	Molecule interacting with CasL	0.068
XNP	CG4548 gene product from transcript CG4548-RA	0.064
synj	synaptojanin	0.064
wb	wing blister	0.064
run	runt	0.062
Nedd4	CG42279 gene product from transcript CG42279-RJ	0.062
Lim3	CG10699 gene product from transcript CG10699-RB	0.060
ct	cut	0.058
Cdc42	CG12530 gene product from transcript CG12530-RA	0.057	Fly
dac	dachshund	0.054
exba	extra bases	0.054
vav	CG7893 gene product from transcript CG7893-RB	0.053
disco	disconnected	0.051
CaMKII	Calcium/calmodulin-dependent protein kinase II	0.050
Fak56D	Focal Adhesion Kinase	0.049
CG31352	CG31352 gene product from transcript CG31352-RA	0.048
btl	breathless	0.048
Sxl	Sex lethal	0.047
Rho1	CG8416 gene product from transcript CG8416-RB	0.045
da	daughterless	0.044
vnd	ventral nervous system defective	0.043
mam	mastermind	0.042
bchs	blue cheese	0.042
CG34168	CG34168 gene product from transcript CG34168-RA	0.040
htl	heartless	0.040
CG12424	CG12424 gene product from transcript CG12424-RC	0.039
RanBPM	Ran-binding protein M	0.037
exex	extra-extra	0.037
Mob2	CG11711 gene product from transcript CG11711-RC	0.037
shi	shibire	0.036
Kr-h1	Kruppel homolog 1	0.035
jeb	jelly belly	0.035
bab1	bric a brac 1	0.035	Fly
Tsp96F	Tetraspanin 96F	0.035
ems	empty spiracles	0.034
pros	prospero	0.033
Ptp99A	Protein tyrosine phosphatase 99A	0.033
mbc	myoblast city	0.033
stau	staufen	0.033
slou	slouch	0.032
ari-2	ariadne 2	0.032
cdi	center divider	0.032
lbl	ladybird late	0.032
oc	ocelliless	0.031
Hr39	Hormone receptor-like in 39	0.031
bsk	basket	0.030
Papss	PAPS synthetase	0.030
siz	schizo	0.029
CG9650	CG9650 gene product from transcript CG9650-RG	0.029
grn	grain	0.029
Pak3	CG14895 gene product from transcript CG14895-RA	0.029
rut	rutabaga	0.029
MED26	Mediator complex subunit 26	0.029
gcm	glial cells missing	0.028
haf	hattifattener	0.028
Mkp3	Mitogen-activated protein kinase phosphatase 3	0.027
kug	kugelei	0.027
p120ctn	Adherens junction protein p120	0.027
CkIalpha	Casein kinase Ialpha	0.027
abd-A	abdominal A	0.027
lin19	lin-19-like	0.027
Ptp52F	CG18243 gene product from transcript CG18243-RB	0.026
mp	multiplexin	0.026
EloA	Elongin A	0.026
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.026
CG2519	CG2519 gene product from transcript CG2519-RB	0.025
milt	milton	0.025
CG14869	CG14869 gene product from transcript CG14869-RB	0.025
Eb1	CG3265 gene product from transcript CG3265-RF	0.025
Btk29A	Btk family kinase at 29A	0.025
sim	single-minded	0.025
Ten-a	Tenascin accessory	0.024
Pak	PAK-kinase	0.024
danr	distal antenna-related	0.024
hts	hu li tai shao	0.023
sty	sprouty	0.023
Cnx99A	Calnexin 99A	0.023
Tsp39D	Tetraspanin 39D	0.023
spdo	sanpodo	0.023
Sra-1	specifically Rac1-associated protein 1	0.022
cora	coracle	0.022
lbm	late bloomer	0.021
egh	egghead	0.021
eve	even skipped	0.021
Scm	Sex comb on midleg	0.021
gish	gilgamesh	0.021
lolal	lola like	0.021	Fly
beat-Ic	beaten path Ic	0.021
if	inflated	0.020
Hr51	Hormone receptor 51	0.020
scb	scab	0.020
dally	division abnormally delayed	0.020
mas	masquerade	0.020
spen	split ends	0.020
unc-104	CG8566 gene product from transcript CG8566-RB	0.019
sn	singed	0.019
retn	retained	0.019
CkIIbeta	Casein kinase II beta subunit	0.018
gogo	golden goal	0.018
Gef64C	Guanine nucleotide exchange factor GEF64C	0.018
erm	earmuff	0.018
pdm3	pou domain motif 3	0.018
Src64B	Src oncogene at 64B	0.018
Mkk4	MAP kinase kinase 4	0.018
CG34449	CG34449 gene product from transcript CG34449-RB	0.017
mira	miranda	0.017
bin	biniou	0.017
Rab5	Rab-protein 5	0.016
cnk	connector enhancer of ksr	0.016
nkd	naked cuticle	0.016
Cip4	CG15015 gene product from transcript CG15015-RA	0.016
gfA	giant fibre A	0.016
chinmo	Chronologically inappropriate morphogenesis	0.016	Fly
Aplip1	APP-like protein interacting protein 1	0.016
fz	frizzled	0.016
oaf	out at first	0.016
sgg	shaggy	0.016
emc	extra macrochaetae	0.015
wg	wingless	0.015
deltaCOP	delta-coatomer protein	0.015
tll	tailless	0.015
sbr	small bristles	0.015
fz2	frizzled 2	0.015
hbn	homeobrain	0.015
oys	oysgedart	0.015
eya	eyes absent	0.015
seq	sequoia	0.015
GATAd	CG5034 gene product from transcript CG5034-RA	0.015
CG17082	CG17082 gene product from transcript CG17082-RD	0.014
trp	transient receptor potential	0.014
NetA	Netrin-A	0.014
Nrt	Neurotactin	0.014
Dhod	Dihydroorotate dehydrogenase	0.014
CBP	sarcoplasmic calcium-binding protein	0.014
SNF4Agamma	SNF4/AMP-activated protein kinase gamma subunit	0.014
Pkc98E	Protein C kinase 98E	0.014
wntD	wnt inhibitor of Dorsal	0.014
CG31740	CG31740 gene product from transcript CG31740-RA	0.013
ap	apterous	0.013
jumu	jumeau	0.013
Pc	Polycomb	0.013
CG13921	CG13921 gene product from transcript CG13921-RB	0.013
Dbx	CG42234 gene product from transcript CG42234-RC	0.013
gsb-n	gooseberry-neuro	0.013
PP2A-B'	CG7913 gene product from transcript CG7913-RK	0.013
Lis-1	Lissencephaly-1	0.012
p130CAS	CG1212 gene product from transcript CG1212-RA	0.012
lap	like-AP180	0.012
tomosyn	CG17762 gene product from transcript CG17762-RB	0.012
mnb	minibrain	0.012
bsh	brain-specific homeobox	0.012
grim	CG4345 gene product from transcript CG4345-RA	0.012
Oatp58Db	Organic anion transporting polypeptide 58Db	0.012
Abi	Abelson interacting protein	0.012
wapl	wings apart-like	0.012
Dab	Disabled	0.012
kni	knirps	0.012
CG31224	CG31224 gene product from transcript CG31224-RA	0.012
CG12029	CG12029 gene product from transcript CG12029-RB	0.012
Pros35	Proteasome 35kD subunit	0.012
CG30497	CG30497 gene product from transcript CG30497-RA	0.012
fd59A	forkhead domain 59A	0.012
moody	CG4322 gene product from transcript CG4322-RD	0.012
tup	tailup	0.011
Dlic	Dynein light intermediate chain	0.011
grau	grauzone	0.011
dnt	doughnut on 2	0.011	Fly
wrapper	CG10382 gene product from transcript CG10382-RA	0.011
msn	misshapen	0.011
CycA	Cyclin A	0.011
dsh	dishevelled	0.011
CG14047	CG14047 gene product from transcript CG14047-RH	0.011
katanin-60	katanin 60	0.011
eIF6	CG17611 gene product from transcript CG17611-RA	0.011
Tre1	trapped in endoderm-1	0.011
unc-119	CG1659 gene product from transcript CG1659-RA	0.011
ric8a	CG15797 gene product from transcript CG15797-RA	0.011
side	sidestep	0.010
eff	effete	0.010
bip1	CG7574 gene product from transcript CG7574-RA	0.010
CG9821	CG9821 gene product from transcript CG9821-RB	0.010
tey	teyrha-meyrha	0.010
Blimp-1	CG5249 gene product from transcript CG5249-RA	0.010
inv	invected	0.010
alphaTub84B	alpha-Tubulin at 84B	0.010
bnl	branchless	0.010
fax	failed axon connections	0.010