Drosophila melanogaster

108 known processes

sc (Dmel_CG3827)

scute

(Aliases: bHLHc28,T4 AS-C,sisb,AS-C T4sc,sis b,T4,sis-b,Hw,sisB,CG3827,AS-C T4,EG:198A6.1,scalpha,ascT4,l(1)1Ba,Sc,sc/T4,Dmel\CG3827,Ac/Sc,DROACS2,scute/sisterlessB)

sc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
malpighian tubule morphogenesis GO:0007443 44 0.777
Fly
neuron fate determination GO:0048664 1 0.709
regionalization GO:0003002 416 0.696
Mouse
renal tubule development GO:0061326 64 0.652
sex determination GO:0007530 18 0.618
sensory organ morphogenesis GO:0090596 260 0.594
Zebrafish
regulation of neural precursor cell proliferation GO:2000177 35 0.556
Mouse
tube morphogenesis GO:0035239 191 0.547
Fly
regulation of notch signaling pathway GO:0008593 100 0.525
Mouse
dorsal ventral pattern formation GO:0009953 133 0.505
Mouse
immune system process GO:0002376 347 0.495
Fly
negative regulation of gene expression GO:0010629 387 0.492
Human Zebrafish
hindgut morphogenesis GO:0007442 58 0.490
Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.486
regulation of neuron differentiation GO:0045664 103 0.481
Human Mouse Worm
stem cell proliferation GO:0072089 88 0.479
Mouse
regulation of mitosis GO:0007088 56 0.466
Fly
renal tubule morphogenesis GO:0061333 44 0.455
Fly
axonogenesis GO:0007409 290 0.443
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.440
Human
transcription from rna polymerase ii promoter GO:0006366 368 0.424
tube development GO:0035295 244 0.420
sensory organ precursor cell fate determination GO:0016360 19 0.405
negative regulation of transcription dna templated GO:0045892 237 0.404
Human
peripheral nervous system development GO:0007422 52 0.399
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.398
Mouse
cell fate specification GO:0001708 71 0.395
Mouse Worm
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.395
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.388
epithelial cell differentiation GO:0030855 322 0.385
Zebrafish Mouse
regulation of cell differentiation GO:0045595 302 0.381
Human Mouse Rat Worm
negative regulation of rna biosynthetic process GO:1902679 240 0.375
Human
gland development GO:0048732 191 0.375
Zebrafish Mouse
telencephalon development GO:0021537 2 0.364
Mouse
forebrain development GO:0030900 2 0.359
Human Zebrafish Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.359
Human
regulation of timing of cell differentiation GO:0048505 1 0.357
Mouse
glial cell differentiation GO:0010001 35 0.356
Mouse
positive regulation of nervous system development GO:0051962 69 0.350
Mouse
axon development GO:0061564 297 0.343
Worm
mitotic nuclear division GO:0007067 213 0.341
Fly
embryonic morphogenesis GO:0048598 206 0.338
Fly
regulation of multicellular organismal development GO:2000026 414 0.336
Human Mouse Rat Worm
negative regulation of cellular metabolic process GO:0031324 382 0.322
Human
neuron projection guidance GO:0097485 241 0.318
Worm
cell division GO:0051301 248 0.306
Worm Fly
neural precursor cell proliferation GO:0061351 75 0.306
Mouse
regulation of cell cycle process GO:0010564 181 0.299
Fly
organonitrogen compound metabolic process GO:1901564 318 0.297
Fly
mesoderm development GO:0007498 78 0.291
stem cell maintenance GO:0019827 67 0.288
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.286
Human
glial cell fate commitment GO:0021781 3 0.284
Mouse
negative regulation of cell differentiation GO:0045596 143 0.273
Human Mouse Rat
cell fate determination involved in pattern specification GO:0060582 19 0.272
antimicrobial humoral response GO:0019730 99 0.264
Fly
stem cell fate commitment GO:0048865 25 0.261
Mouse Worm
negative regulation of rna metabolic process GO:0051253 251 0.258
Human
notch signaling pathway GO:0007219 120 0.258
Human Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.257
Human
epidermal cell differentiation GO:0009913 51 0.253
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.252
nephron epithelium morphogenesis GO:0072088 3 0.250
positive regulation of biosynthetic process GO:0009891 316 0.249
segmentation GO:0035282 207 0.245
gliogenesis GO:0042063 80 0.243
Mouse Rat
glial cell development GO:0021782 27 0.243
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.242
Human
hindbrain development GO:0030902 2 0.241
Zebrafish Mouse
axon guidance GO:0007411 233 0.237
Worm
positive regulation of signal transduction GO:0009967 223 0.236
Mouse
regulation of organelle organization GO:0033043 196 0.235
Fly
positive regulation of response to stimulus GO:0048584 323 0.234
Mouse
neurological system process GO:0050877 358 0.233
regulation of mitotic cell cycle GO:0007346 190 0.229
Mouse Fly
positive regulation of transcription dna templated GO:0045893 266 0.227
nephron tubule morphogenesis GO:0072078 3 0.221
regulation of gliogenesis GO:0014013 11 0.218
Rat
salivary gland development GO:0007431 162 0.216
respiratory system development GO:0060541 213 0.216
Mouse
regulation of oviposition GO:0046662 14 0.216
Worm
positive regulation of neural precursor cell proliferation GO:2000179 8 0.216
Mouse
head development GO:0060322 135 0.214
Human Zebrafish Mouse
nephron morphogenesis GO:0072028 3 0.214
imaginal disc pattern formation GO:0007447 91 0.211
positive regulation of gene expression GO:0010628 290 0.210
nuclear division GO:0000280 332 0.210
Fly
cellular response to dna damage stimulus GO:0006974 223 0.209
compound eye development GO:0048749 307 0.208
digestive tract development GO:0048565 149 0.204
Mouse Fly
regulation of glial cell differentiation GO:0045685 1 0.203
epithelial cell development GO:0002064 274 0.202
Zebrafish
nephron tubule development GO:0072080 3 0.200
eye morphogenesis GO:0048592 260 0.200
organelle fission GO:0048285 340 0.199
Fly
formation of organ boundary GO:0010160 30 0.198
antimicrobial peptide production GO:0002775 46 0.197
Fly
renal system development GO:0072001 72 0.196
regulation of neuroblast proliferation GO:1902692 34 0.196
tissue morphogenesis GO:0048729 297 0.194
Fly
regulation of cell development GO:0060284 215 0.192
Human Mouse Rat Worm
gland morphogenesis GO:0022612 145 0.192
compound eye morphogenesis GO:0001745 249 0.192
cell fate commitment involved in pattern specification GO:0060581 31 0.190
Mouse
neuroblast proliferation GO:0007405 74 0.188
Mouse
urogenital system development GO:0001655 72 0.185
segment specification GO:0007379 33 0.184
startle response GO:0001964 16 0.182
negative regulation of cellular biosynthetic process GO:0031327 277 0.182
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.178
regulation of production of molecular mediator of immune response GO:0002700 44 0.177
Fly
hair cell differentiation GO:0035315 47 0.173
regulation of neuron projection development GO:0010975 69 0.172
Worm
sensory organ boundary specification GO:0008052 22 0.171
epithelial tube morphogenesis GO:0060562 88 0.169
Fly
kidney morphogenesis GO:0060993 3 0.169
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.168
Human
tyrosine phosphorylation of stat protein GO:0007260 1 0.167
regulation of cell cycle GO:0051726 291 0.166
Mouse Fly
r7 cell differentiation GO:0045466 43 0.166
kidney epithelium development GO:0072073 3 0.163
hindgut development GO:0061525 58 0.162
Fly
morphogenesis of an epithelium GO:0002009 276 0.161
Fly
regulation of cell morphogenesis GO:0022604 163 0.161
Worm
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.161
central nervous system development GO:0007417 201 0.158
Human Zebrafish Mouse
developmental maturation GO:0021700 172 0.158
Zebrafish Mouse
positive regulation of signaling GO:0023056 243 0.158
Mouse
growth GO:0040007 359 0.157
Zebrafish Worm
photoreceptor cell differentiation GO:0046530 170 0.157
negative regulation of multicellular organismal process GO:0051241 142 0.156
Human Rat
positive regulation of rna biosynthetic process GO:1902680 266 0.156
multi multicellular organism process GO:0044706 123 0.155
Worm
taxis GO:0042330 304 0.154
Worm
digestive system development GO:0055123 149 0.154
Mouse Fly
regulation of nuclear division GO:0051783 58 0.153
Fly
neuron projection extension GO:1990138 32 0.152
Worm
regulation of gene expression epigenetic GO:0040029 128 0.150
biological adhesion GO:0022610 138 0.148
neuronal stem cell maintenance GO:0097150 4 0.148
nephron development GO:0072006 3 0.148
regulation of cell division GO:0051302 72 0.146
Worm Fly
exocrine system development GO:0035272 162 0.145
cellular ketone metabolic process GO:0042180 24 0.145
cell proliferation GO:0008283 299 0.145
Mouse Rat Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.144
Worm
dosage compensation GO:0007549 16 0.142
r1 r6 cell differentiation GO:0048052 4 0.141
salivary gland morphogenesis GO:0007435 145 0.141
regulation of antimicrobial peptide production GO:0002784 44 0.141
Fly
regulation of immune system process GO:0002682 176 0.140
Fly
brain development GO:0007420 120 0.138
Human Zebrafish Mouse
response to external biotic stimulus GO:0043207 293 0.138
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.135
nephron epithelium development GO:0072009 3 0.135
immune effector process GO:0002252 98 0.134
Fly
larval behavior GO:0030537 42 0.132
chaeta development GO:0022416 97 0.131
eye development GO:0001654 323 0.130
organic acid metabolic process GO:0006082 103 0.130
positive regulation of bmp signaling pathway GO:0030513 5 0.129
compound eye photoreceptor cell differentiation GO:0001751 140 0.128
connective tissue development GO:0061448 3 0.128
regulation of anatomical structure size GO:0090066 163 0.127
Worm
regulation of neurogenesis GO:0050767 158 0.126
Human Mouse Rat Worm
negative regulation of gliogenesis GO:0014014 6 0.125
Rat
multi organism reproductive behavior GO:0044705 121 0.123
Worm
axon ensheathment in central nervous system GO:0032291 3 0.122
dendrite morphogenesis GO:0048813 199 0.122
stem cell development GO:0048864 79 0.121
Mouse
neuron fate commitment GO:0048663 50 0.121
Human Mouse
protein complex biogenesis GO:0070271 201 0.121
negative regulation of mitotic cell cycle GO:0045930 109 0.118
Fly
oxoacid metabolic process GO:0043436 103 0.118
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.118
negative regulation of neurogenesis GO:0050768 53 0.116
Human Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.115
Worm
anterior posterior pattern specification GO:0009952 136 0.115
camera type eye development GO:0043010 4 0.114
developmental cell growth GO:0048588 52 0.114
Worm
cellular amino acid metabolic process GO:0006520 61 0.114
small molecule metabolic process GO:0044281 305 0.114
eye photoreceptor cell differentiation GO:0001754 145 0.114
humoral immune response GO:0006959 117 0.114
Fly
kidney development GO:0001822 3 0.113
single organism behavior GO:0044708 391 0.112
carboxylic acid metabolic process GO:0019752 92 0.112
positive regulation of multicellular organismal process GO:0051240 143 0.111
Mouse
localization of cell GO:0051674 257 0.111
Mouse Worm
immune response GO:0006955 246 0.111
Fly
open tracheal system development GO:0007424 204 0.111
chemotaxis GO:0006935 249 0.110
Worm
negative regulation of developmental process GO:0051093 201 0.110
Human Mouse Rat
regulation of cell proliferation GO:0042127 163 0.109
Mouse Rat
developmental growth GO:0048589 280 0.109
Zebrafish Worm
body morphogenesis GO:0010171 2 0.108
Worm
cranial nerve development GO:0021545 1 0.108
organ formation GO:0048645 39 0.105
axon extension GO:0048675 32 0.105
Worm
regulation of cellular ketone metabolic process GO:0010565 3 0.104
regulation of immune effector process GO:0002697 52 0.103
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.102
glial cell proliferation GO:0014009 13 0.102
Rat
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.102
cell maturation GO:0048469 144 0.101
Zebrafish Mouse
negative regulation of cell development GO:0010721 62 0.101
Human Rat
stem cell differentiation GO:0048863 117 0.101
Mouse Worm
protein complex assembly GO:0006461 200 0.100
embryonic epithelial tube formation GO:0001838 6 0.099
positive regulation of cell differentiation GO:0045597 64 0.099
Mouse
multicellular organismal reproductive behavior GO:0033057 110 0.099
Worm
positive regulation of rna metabolic process GO:0051254 271 0.099
wing disc pattern formation GO:0035222 66 0.095
multi organism behavior GO:0051705 175 0.094
Worm
epidermis development GO:0008544 65 0.093
peptide biosynthetic process GO:0043043 42 0.092
Fly
cell fate determination GO:0001709 91 0.092
Mouse
tube formation GO:0035148 21 0.091
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.091
antimicrobial peptide biosynthetic process GO:0002777 38 0.090
Fly
response to abiotic stimulus GO:0009628 341 0.089
Human
skin development GO:0043588 65 0.088
negative regulation of immune system process GO:0002683 50 0.088
macromolecular complex assembly GO:0065003 256 0.087
nephron tubule formation GO:0072079 3 0.087
positive regulation of cellular biosynthetic process GO:0031328 316 0.086
cellular amine metabolic process GO:0044106 12 0.085
negative regulation of cell cycle GO:0045786 116 0.085
Fly
embryonic organ development GO:0048568 50 0.084
Human Mouse
negative regulation of cell cycle process GO:0010948 109 0.084
Fly
positive regulation of nucleic acid templated transcription GO:1903508 266 0.084
dendrite development GO:0016358 204 0.083
regulation of developmental growth GO:0048638 174 0.081
Worm
cellular protein modification process GO:0006464 438 0.079
adult locomotory behavior GO:0008344 76 0.079
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.079
positive regulation of cell cycle GO:0045787 43 0.079
Mouse
positive regulation of cellular amine metabolic process GO:0033240 0 0.079
larval locomotory behavior GO:0008345 27 0.079
regulation of epithelial cell differentiation GO:0030856 4 0.078
Mouse
positive regulation of developmental process GO:0051094 143 0.077
Mouse
regulation of humoral immune response GO:0002920 51 0.077
Fly
regulation of cell projection organization GO:0031344 92 0.076
Worm
adult behavior GO:0030534 137 0.076
regulation of stem cell proliferation GO:0072091 40 0.076
cell motility GO:0048870 251 0.075
Mouse Worm
cellular amide metabolic process GO:0043603 80 0.075
Fly
hematopoietic or lymphoid organ development GO:0048534 57 0.074
response to decreased oxygen levels GO:0036293 58 0.074
Human
regulation of bmp signaling pathway GO:0030510 23 0.074
rhythmic process GO:0048511 106 0.073
regulation of glial cell proliferation GO:0060251 11 0.073
Rat
cell growth GO:0016049 108 0.072
Worm
immune system development GO:0002520 57 0.072
neuron fate specification GO:0048665 12 0.071
Mouse
protein modification process GO:0036211 438 0.071
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.071
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.070
cell death GO:0008219 279 0.070
regulation of response to stress GO:0080134 200 0.070
cell adhesion GO:0007155 136 0.069
regulation of axon extension involved in axon guidance GO:0048841 4 0.069
Worm
regulation of cellular amine metabolic process GO:0033238 3 0.068
regulation of antimicrobial humoral response GO:0002759 50 0.066
Fly
regulation of response to external stimulus GO:0032101 115 0.066
Worm Fly
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.066
regulation of axon extension GO:0030516 8 0.066
Worm
negative regulation of glial cell proliferation GO:0060253 6 0.065
Rat
response to hypoxia GO:0001666 53 0.065
Human
malpighian tubule development GO:0072002 64 0.065
neuroepithelial cell differentiation GO:0060563 6 0.065
Mouse
regulation of nervous system development GO:0051960 248 0.065
Human Mouse Rat Worm
smoothened signaling pathway GO:0007224 49 0.064
hemopoiesis GO:0030097 46 0.064
hematopoietic progenitor cell differentiation GO:0002244 1 0.064
digestive tract morphogenesis GO:0048546 127 0.062
Fly
spinal cord development GO:0021510 1 0.062
Mouse
nerve development GO:0021675 6 0.062
phosphorylation GO:0016310 294 0.061
negative regulation of stem cell differentiation GO:2000737 8 0.061
embryonic hindgut morphogenesis GO:0048619 48 0.061
Fly
negative regulation of programmed cell death GO:0043069 72 0.059
response to biotic stimulus GO:0009607 294 0.059
Fly
regulation of localization GO:0032879 275 0.058
Worm
central nervous system neuron differentiation GO:0021953 8 0.058
Human Mouse
response to wounding GO:0009611 94 0.058
Zebrafish
neuron recognition GO:0008038 101 0.057
locomotory behavior GO:0007626 176 0.057
bmp signaling pathway GO:0030509 27 0.056
intracellular signal transduction GO:0035556 300 0.055
regulation of response to dna damage stimulus GO:2001020 23 0.054
regulation of phosphorus metabolic process GO:0051174 210 0.054
peptide metabolic process GO:0006518 80 0.053
Fly
enzyme linked receptor protein signaling pathway GO:0007167 179 0.053
formation of anatomical boundary GO:0048859 37 0.051
amine metabolic process GO:0009308 12 0.050
positive regulation of protein metabolic process GO:0051247 128 0.048
negative regulation of nervous system development GO:0051961 92 0.047
Human Rat
regulation of intracellular signal transduction GO:1902531 236 0.047
production of molecular mediator of immune response GO:0002440 46 0.047
Fly
proximal distal pattern formation GO:0009954 15 0.047
positive regulation of cell development GO:0010720 61 0.047
Mouse
somatic sex determination GO:0018993 2 0.046
positive regulation of notch signaling pathway GO:0045747 34 0.046
Mouse
regulation of programmed cell death GO:0043067 152 0.045
regulation of immune response GO:0050776 118 0.045
Fly
negative regulation of notch signaling pathway GO:0045746 41 0.045
regulation of axonogenesis GO:0050770 32 0.045
Worm
response to oxygen containing compound GO:1901700 200 0.045
Human
peptidyl tyrosine modification GO:0018212 24 0.044
positive regulation of phosphate metabolic process GO:0045937 139 0.044
regulation of cell growth GO:0001558 43 0.043
Worm
blastoderm segmentation GO:0007350 159 0.043
peripheral nervous system neuron development GO:0048935 8 0.043
cell migration GO:0016477 238 0.043
Mouse Worm
regulation of cell shape GO:0008360 113 0.042
neuron death GO:0070997 27 0.042
Mouse
embryonic pattern specification GO:0009880 174 0.042
positive regulation of phosphorus metabolic process GO:0010562 139 0.041
regulation of cellular component size GO:0032535 98 0.041
Worm
peptidyl amino acid modification GO:0018193 105 0.040
sex determination establishment of x a ratio GO:0007540 1 0.040
wound healing GO:0042060 75 0.040
Zebrafish
jak stat cascade GO:0007259 49 0.040
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.040
response to other organism GO:0051707 293 0.039
Fly
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.039
Fly
gastrulation GO:0007369 70 0.039
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.038
peripheral nervous system neuron differentiation GO:0048934 8 0.038
regulation of cellular protein metabolic process GO:0032268 243 0.038
positive regulation of phosphorylation GO:0042327 87 0.038
positive regulation of cell proliferation GO:0008284 47 0.037
Mouse
positive regulation of organelle organization GO:0010638 65 0.037
asymmetric cell division GO:0008356 37 0.037
Worm
regulation of cellular response to stress GO:0080135 89 0.037
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.036
Fly
stem cell fate determination GO:0048867 15 0.036
Mouse
negative regulation of cellular component organization GO:0051129 108 0.035
Fly
positive regulation of cell communication GO:0010647 250 0.035
Mouse
protein phosphorylation GO:0006468 169 0.035
regulation of growth GO:0040008 233 0.035
Worm
response to organic substance GO:0010033 284 0.035
Human
wing disc dorsal ventral pattern formation GO:0048190 47 0.035
positive regulation of intracellular signal transduction GO:1902533 116 0.034
regulation of reproductive process GO:2000241 54 0.034
Worm
regulation of embryonic development GO:0045995 68 0.034
stem cell fate specification GO:0048866 2 0.034
Worm
organonitrogen compound biosynthetic process GO:1901566 117 0.034
Fly
regulation of behavior GO:0050795 75 0.034
Worm
primary sex determination soma GO:0007539 2 0.034
cell cell signaling involved in cell fate commitment GO:0045168 210 0.033
peptidyl tyrosine phosphorylation GO:0018108 24 0.033
columnar cuboidal epithelial cell development GO:0002066 249 0.033
appendage development GO:0048736 401 0.033
regulation of apoptotic process GO:0042981 130 0.033
lateral inhibition GO:0046331 206 0.032
positive regulation of stem cell proliferation GO:2000648 8 0.031
regulation of membrane potential GO:0042391 35 0.031
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.030
Fly
apoptotic process GO:0006915 159 0.030
negative regulation of cell division GO:0051782 17 0.029
Fly
morphogenesis of embryonic epithelium GO:0016331 94 0.029
regulation of stem cell differentiation GO:2000736 14 0.029
sensory perception GO:0007600 196 0.029
positive regulation of cellular protein metabolic process GO:0032270 118 0.029
imaginal disc derived appendage morphogenesis GO:0035114 395 0.029
positive regulation of cell cycle process GO:0090068 28 0.029
positive regulation of cellular component organization GO:0051130 156 0.029
negative regulation of organelle organization GO:0010639 56 0.028
Fly
gastrulation with mouth forming first GO:0001703 36 0.028
amide biosynthetic process GO:0043604 42 0.028
Fly
regulation of response to biotic stimulus GO:0002831 63 0.028
Fly
regulation of cellular component movement GO:0051270 42 0.028
Worm
response to oxygen levels GO:0070482 59 0.028
Human
negative regulation of neuron differentiation GO:0045665 16 0.028
Human
transmission of nerve impulse GO:0019226 12 0.027
neuronal action potential GO:0019228 10 0.027
mitotic spindle organization GO:0007052 220 0.027
ovarian follicle cell development GO:0030707 248 0.027
positive regulation of neurogenesis GO:0050769 41 0.026
Mouse
regulation of phosphorylation GO:0042325 147 0.026
epithelial tube formation GO:0072175 7 0.026
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.026
response to lipopolysaccharide GO:0032496 4 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
regulation of neuron death GO:1901214 26 0.025
Mouse
central nervous system neuron development GO:0021954 8 0.025
Mouse
death GO:0016265 284 0.025
gastrulation involving germ band extension GO:0010004 36 0.025
regulation of phosphate metabolic process GO:0019220 210 0.025
positive regulation of neuron differentiation GO:0045666 26 0.024
Mouse
cellular macromolecule localization GO:0070727 220 0.024
regulation of protein metabolic process GO:0051246 256 0.023
regulation of locomotion GO:0040012 42 0.023
Worm
positive regulation of mitotic cell cycle GO:0045931 34 0.023
malpighian tubule tip cell differentiation GO:0061382 9 0.022
regulation of molecular function GO:0065009 217 0.022
gene silencing GO:0016458 138 0.022
wing disc morphogenesis GO:0007472 344 0.022
brain morphogenesis GO:0048854 16 0.022
positive regulation of molecular function GO:0044093 136 0.022
negative regulation of cell communication GO:0010648 223 0.022
oviposition GO:0018991 19 0.022
Worm
neuromuscular process GO:0050905 21 0.021
regulation of protein phosphorylation GO:0001932 64 0.021
chaeta morphogenesis GO:0008407 42 0.021
organic substance transport GO:0071702 257 0.021
regulation of multi organism process GO:0043900 131 0.021
Worm Fly
response to lipid GO:0033993 38 0.021
Human
regulation of cell death GO:0010941 173 0.021
defense response to other organism GO:0098542 225 0.021
regulation of catalytic activity GO:0050790 185 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
positive regulation of catalytic activity GO:0043085 118 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
regulation of cell size GO:0008361 63 0.019
Worm
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.019
positive regulation of growth GO:0045927 75 0.019
Worm
bolwig s organ development GO:0055034 8 0.019
cell recognition GO:0008037 102 0.019
retina development in camera type eye GO:0060041 4 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.018
lipid metabolic process GO:0006629 121 0.018
positive regulation of protein phosphorylation GO:0001934 34 0.018
response to monosaccharide GO:0034284 4 0.018
regulation of cell fate specification GO:0042659 27 0.018
single organism biosynthetic process GO:0044711 206 0.018
multicellular organismal signaling GO:0035637 12 0.018
innate immune response GO:0045087 144 0.018
catabolic process GO:0009056 409 0.018
developmental growth involved in morphogenesis GO:0060560 65 0.017
Worm
anterior posterior axis specification embryo GO:0008595 103 0.017
positive regulation of protein modification process GO:0031401 58 0.017
negative regulation of cell death GO:0060548 81 0.017
musculoskeletal movement GO:0050881 3 0.017
Mouse
chromosome organization GO:0051276 360 0.017
spindle organization GO:0007051 253 0.017
negative regulation of apoptotic process GO:0043066 63 0.017
cholesterol homeostasis GO:0042632 3 0.017
chorion containing eggshell formation GO:0007304 105 0.017
cell type specific apoptotic process GO:0097285 38 0.016
Mouse
camera type eye morphogenesis GO:0048593 2 0.016
compound eye photoreceptor development GO:0042051 78 0.016
positive regulation of protein kinase activity GO:0045860 25 0.016
phagocytosis GO:0006909 215 0.016
larval development GO:0002164 104 0.016
Worm
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
positive regulation of neuroblast proliferation GO:0002052 7 0.016
ensheathment of neurons GO:0007272 10 0.016
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.016
Worm
vesicle mediated transport GO:0016192 381 0.016
defense response to bacterium GO:0042742 178 0.016
organic substance catabolic process GO:1901575 308 0.016
tripartite regional subdivision GO:0007351 103 0.016
leg disc development GO:0035218 92 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
circadian rhythm GO:0007623 105 0.015
mesenchymal cell differentiation GO:0048762 1 0.015
establishment of planar polarity GO:0001736 87 0.015
protein transport GO:0015031 155 0.015
cellular response to organic substance GO:0071310 132 0.015
eye photoreceptor cell development GO:0042462 81 0.015
locomotor rhythm GO:0045475 56 0.015
neuron apoptotic process GO:0051402 17 0.015
Mouse
intracellular transport GO:0046907 228 0.015
establishment of localization in cell GO:0051649 402 0.015
establishment of tissue polarity GO:0007164 87 0.015
establishment of protein localization GO:0045184 163 0.015
single organism catabolic process GO:0044712 228 0.015
muscle cell development GO:0055001 50 0.015
response to hexose GO:0009746 3 0.014
positive regulation of programmed cell death GO:0043068 62 0.014
Mouse Worm
eye photoreceptor cell fate commitment GO:0042706 37 0.014
chromosome segregation GO:0007059 157 0.014
action potential GO:0001508 13 0.014
neural retina development GO:0003407 4 0.014
chromatin modification GO:0016568 147 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
reproductive structure development GO:0048608 74 0.014
Human Mouse
l amino acid import GO:0043092 2 0.014
vitamin metabolic process GO:0006766 2 0.014
actin filament based process GO:0030029 220 0.014
immune response regulating signaling pathway GO:0002764 2 0.014
mesenchymal cell development GO:0014031 1 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.014
regulation of epidermal cell differentiation GO:0045604 3 0.013
somatic stem cell maintenance GO:0035019 14 0.013
Mouse

sc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.218
bone disease DOID:0080001 0 0.142
musculoskeletal system disease DOID:17 0 0.142
connective tissue disease DOID:65 0 0.142
bone development disease DOID:0080006 0 0.136
dysostosis DOID:1934 0 0.136
spondylocostal dysostosis DOID:0050568 0 0.029
disease of metabolism DOID:0014667 0 0.020
inherited metabolic disorder DOID:655 0 0.020
cardiovascular system disease DOID:1287 0 0.016