IMP

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Drosophila melanogaster

0 genes annotated in fly

dysostosis

DOID:1934

A bone development disease that results in defective ossification of located in bone.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "dysostosis" (in gray)

Name	Description	Probability	Func Analog Organism
E(spl)	Enhancer of split	0.974	Human
HLHm7	E(spl) region transcript m7	0.939	Human
HLHmdelta	E(spl) region transcript mdelta	0.935	Human
HLHmbeta	E(spl) region transcript mbeta	0.831	Human
HLHm5	E(spl) region transcript m5	0.823	Human
malpha	E(spl) region transcript malpha	0.740
HLHmgamma	E(spl) region transcript mgamma	0.640	Human
HLHm3	E(spl) region transcript m3	0.569	Human
m4	E(spl) region transcript m4	0.517
m2	E(spl) region transcript m2	0.476
ac	achaete	0.413
bnl	branchless	0.376
Tom	Twin of m4	0.295
hh	hedgehog	0.272
stumps	CG31317 gene product from transcript CG31317-RC	0.238
sc	scute	0.136
Ras85D	Ras oncogene at 85D	0.128
dpp	decapentaplegic	0.118	Human
brm	brahma	0.105
N	Notch	0.098
l(2)gl	lethal (2) giant larvae	0.077
eIF-4E	Eukaryotic initiation factor 4E	0.067
Tor	Target of rapamycin	0.052
sr	stripe	0.049
tap	target of Poxn	0.048
Dref	DNA replication-related element factor	0.043
Dl	Delta	0.043	Human
arm	armadillo	0.038
Su(var)205	Suppressor of variegation 205	0.038
noc	no ocelli	0.036
sca	scabrous	0.032
tin	tinman	0.029
BobA	Brother of Bearded A	0.028
CG8965	CG8965 gene product from transcript CG8965-RA	0.027
ci	cubitus interruptus	0.026	Human
phl	pole hole	0.026
Aos1	CG12276 gene product from transcript CG12276-RA	0.025
zfh1	Zn finger homeodomain 1	0.025
Mrtf	Myocardin-related transcription factor	0.024
en	engrailed	0.023
btl	breathless	0.020	Human
htl	heartless	0.020	Human
nrv2	nervana 2	0.018
ato	atonal	0.017
Hs6st	Heparan sulfate 6-O-sulfotransferase	0.017
Rpb5	CG11979 gene product from transcript CG11979-RA	0.016
stg	string	0.016
twi	twist	0.016	Human
Tl	Toll	0.016
Egfr	Epidermal growth factor receptor	0.016
CG9797	CG9797 gene product from transcript CG9797-RA	0.016
ase	asense	0.016
dlg1	discs large 1	0.015
sax	saxophone	0.015
CG15365	CG15365 gene product from transcript CG15365-RA	0.014
cg	combgap	0.014
emc	extra macrochaetae	0.014
zfh2	Zn finger homeodomain 2	0.014
bib	big brain	0.014
asp	abnormal spindle	0.013
Set	CG4299 gene product from transcript CG4299-RA	0.013
m6	E(spl) region transcript m6	0.012
sog	short gastrulation	0.012
H	Hairless	0.012
CG6051	CG6051 gene product from transcript CG6051-RB	0.012
Caf1	Chromatin assembly factor 1 subunit	0.012
mam	mastermind	0.012
amos	absent MD neurons and olfactory sensilla	0.011
eya	eyes absent	0.011
CG7028	CG7028 gene product from transcript CG7028-RA	0.011
MED22	Mediator complex subunit 22	0.011
CycA	Cyclin A	0.011
RnpS1	RNA-binding protein S1	0.011
pan	pangolin	0.011
geminin	CG3183 gene product from transcript CG3183-RA	0.011
srp	serpent	0.010