Drosophila melanogaster

53 known processes

shtd (Dmel_CG9198)

shattered

(Aliases: Dmel\CG9198,Apc1,CG9198)

shtd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axonogenesis GO:0007409 290 0.571
regulation of neurogenesis GO:0050767 158 0.356
axon development GO:0061564 297 0.237
endocytosis GO:0006897 310 0.210
vesicle mediated transport GO:0016192 381 0.209
organelle localization GO:0051640 148 0.188
Worm
mitotic cell cycle phase transition GO:0044772 138 0.188
Worm
mitotic cytokinesis GO:0000281 50 0.167
regulation of mitotic cell cycle GO:0007346 190 0.149
Worm
proteolysis GO:0006508 192 0.140
body morphogenesis GO:0010171 2 0.139
chromosome separation GO:0051304 42 0.138
Worm
regulation of mitotic cell cycle phase transition GO:1901990 130 0.137
cell cycle phase transition GO:0044770 140 0.136
Worm
positive regulation of macromolecule metabolic process GO:0010604 405 0.133
neuron recognition GO:0008038 101 0.126
dna replication GO:0006260 48 0.125
neuron projection guidance GO:0097485 241 0.122
positive regulation of catabolic process GO:0009896 105 0.117
eye development GO:0001654 323 0.114
positive regulation of gene expression GO:0010628 290 0.111
mrna metabolic process GO:0016071 124 0.109
telomere capping GO:0016233 11 0.106
regulation of neuron differentiation GO:0045664 103 0.103
regulation of cell cycle GO:0051726 291 0.103
Worm
gliogenesis GO:0042063 80 0.098
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.097
catabolic process GO:0009056 409 0.094
negative regulation of neuroblast proliferation GO:0007406 27 0.094
positive regulation of response to stimulus GO:0048584 323 0.090
regulation of microtubule based process GO:0032886 49 0.087
regulation of cellular catabolic process GO:0031329 157 0.084
organic substance catabolic process GO:1901575 308 0.083
negative regulation of cell cycle phase transition GO:1901988 103 0.082
taxis GO:0042330 304 0.079
positive regulation of signal transduction GO:0009967 223 0.076
carboxylic acid metabolic process GO:0019752 92 0.073
mrna processing GO:0006397 104 0.071
cellular catabolic process GO:0044248 372 0.071
axon guidance GO:0007411 233 0.070
nuclear division GO:0000280 332 0.068
assembly of actomyosin apparatus involved in cytokinesis GO:0000912 11 0.068
single organism biosynthetic process GO:0044711 206 0.068
mitotic sister chromatid separation GO:0051306 30 0.067
Worm
phagocytosis GO:0006909 215 0.066
positive regulation of cellular biosynthetic process GO:0031328 316 0.065
meiotic cell cycle process GO:1903046 132 0.065
Worm
regulation of mitotic sister chromatid separation GO:0010965 28 0.065
Worm
cellular macromolecule catabolic process GO:0044265 136 0.064
mitotic nuclear division GO:0007067 213 0.063
positive regulation of rna biosynthetic process GO:1902680 266 0.063
metaphase anaphase transition of cell cycle GO:0044784 28 0.063
Worm
protein complex biogenesis GO:0070271 201 0.063
regulation of mitotic sister chromatid segregation GO:0033047 28 0.062
Worm
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.061
transcription from rna polymerase ii promoter GO:0006366 368 0.058
mitotic sister chromatid segregation GO:0000070 87 0.058
Worm
photoreceptor cell differentiation GO:0046530 170 0.057
positive regulation of rna metabolic process GO:0051254 271 0.056
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.056
regulation of molecular function GO:0065009 217 0.056
cellular protein modification process GO:0006464 438 0.055
Human
positive regulation of cell communication GO:0010647 250 0.055
negative regulation of mitotic cell cycle GO:0045930 109 0.054
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.054
Worm
organelle fission GO:0048285 340 0.054
regulation of cell cycle process GO:0010564 181 0.052
Worm
growth GO:0040007 359 0.052
regulation of neuron projection development GO:0010975 69 0.051
positive regulation of biosynthetic process GO:0009891 316 0.051
dendrite development GO:0016358 204 0.050
purine nucleoside triphosphate metabolic process GO:0009144 119 0.049
purine ribonucleoside metabolic process GO:0046128 127 0.047
developmental programmed cell death GO:0010623 138 0.044
positive regulation of nucleic acid templated transcription GO:1903508 266 0.043
small molecule metabolic process GO:0044281 305 0.042
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.042
dna biosynthetic process GO:0071897 24 0.042
regulation of sister chromatid segregation GO:0033045 28 0.041
Worm
positive regulation of neurogenesis GO:0050769 41 0.041
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.040
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.038
regulation of cell cycle phase transition GO:1901987 130 0.037
epithelial cell development GO:0002064 274 0.037
regulation of meiosis GO:0040020 3 0.036
single organism catabolic process GO:0044712 228 0.036
Worm
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.035
purine containing compound metabolic process GO:0072521 155 0.035
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.035
dendrite morphogenesis GO:0048813 199 0.035
programmed cell death GO:0012501 257 0.035
Worm
detection of external stimulus GO:0009581 66 0.035
cell death GO:0008219 279 0.034
Worm
cytoskeleton dependent cytokinesis GO:0061640 81 0.034
dorsal ventral pattern formation GO:0009953 133 0.033
organonitrogen compound metabolic process GO:1901564 318 0.033
positive regulation of signaling GO:0023056 243 0.033
mitotic g2 dna damage checkpoint GO:0007095 69 0.033
organic acid metabolic process GO:0006082 103 0.033
compound eye photoreceptor cell differentiation GO:0001751 140 0.033
eye photoreceptor cell differentiation GO:0001754 145 0.032
regulation of catabolic process GO:0009894 170 0.032
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.032
neuroblast proliferation GO:0007405 74 0.031
chromatin organization GO:0006325 207 0.031
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
meiotic cell cycle GO:0051321 171 0.030
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
purine nucleotide catabolic process GO:0006195 109 0.030
amine metabolic process GO:0009308 12 0.029
wnt signaling pathway GO:0016055 98 0.029
aromatic compound catabolic process GO:0019439 166 0.029
dna integrity checkpoint GO:0031570 81 0.029
cellular response to dna damage stimulus GO:0006974 223 0.029
regulation of chromosome segregation GO:0051983 32 0.028
Worm
cell division GO:0051301 248 0.028
Worm
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.028
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.028
positive regulation of transcription dna templated GO:0045893 266 0.028
mitotic dna damage checkpoint GO:0044773 74 0.028
mitotic cell cycle checkpoint GO:0007093 88 0.027
positive regulation of wnt signaling pathway GO:0030177 25 0.027
regulation of embryonic development GO:0045995 68 0.027
compound eye development GO:0048749 307 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.026
cell cycle checkpoint GO:0000075 95 0.026
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.026
intracellular signal transduction GO:0035556 300 0.025
oxoacid metabolic process GO:0043436 103 0.025
macromolecular complex assembly GO:0065003 256 0.025
salivary gland cell autophagic cell death GO:0035071 83 0.025
positive regulation of cell differentiation GO:0045597 64 0.024
autophagic cell death GO:0048102 83 0.024
gland development GO:0048732 191 0.024
negative regulation of cell cycle GO:0045786 116 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
regulation of growth GO:0040008 233 0.024
cytokinesis GO:0000910 90 0.024
reproductive system development GO:0061458 74 0.023
wing disc pattern formation GO:0035222 66 0.023
regulation of erbb signaling pathway GO:1901184 42 0.023
response to radiation GO:0009314 155 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
positive regulation of protein catabolic process GO:0045732 34 0.023
tissue death GO:0016271 102 0.023
cell motility GO:0048870 251 0.023
peptidyl amino acid modification GO:0018193 105 0.022
compound eye morphogenesis GO:0001745 249 0.022
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.022
organic substance transport GO:0071702 257 0.022
regulation of mitosis GO:0007088 56 0.022
Worm
purine ribonucleotide metabolic process GO:0009150 145 0.021
modification dependent protein catabolic process GO:0019941 78 0.021
tube morphogenesis GO:0035239 191 0.021
neuron fate commitment GO:0048663 50 0.021
regulation of cell division GO:0051302 72 0.021
Worm
response to biotic stimulus GO:0009607 294 0.021
single organism cellular localization GO:1902580 180 0.020
Worm
regulation of cell proliferation GO:0042127 163 0.020
glial cell differentiation GO:0010001 35 0.020
salivary gland development GO:0007431 162 0.020
mrna splice site selection GO:0006376 1 0.020
mitotic spindle stabilization GO:0043148 6 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
organophosphate metabolic process GO:0019637 195 0.020
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.020
negative regulation of cell cycle process GO:0010948 109 0.020
regulation of nervous system development GO:0051960 248 0.020
rna processing GO:0006396 147 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.019
protein modification process GO:0036211 438 0.019
Human
lipid metabolic process GO:0006629 121 0.019
positive regulation of cellular protein catabolic process GO:1903364 24 0.019
compound eye photoreceptor development GO:0042051 78 0.019
nucleobase containing compound catabolic process GO:0034655 165 0.019
respiratory system development GO:0060541 213 0.019
dna damage checkpoint GO:0000077 78 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
single organism intracellular transport GO:1902582 207 0.019
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.019
regulation of nuclear division GO:0051783 58 0.019
Worm
imaginal disc derived appendage development GO:0048737 399 0.019
protein complex assembly GO:0006461 200 0.018
histone mrna metabolic process GO:0008334 8 0.018
nucleotide metabolic process GO:0009117 161 0.018
regulation of proteasomal protein catabolic process GO:0061136 39 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
mitotic dna integrity checkpoint GO:0044774 75 0.018
actomyosin contractile ring assembly GO:0000915 10 0.018
development of primary sexual characteristics GO:0045137 50 0.018
axonal fasciculation GO:0007413 12 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
eye photoreceptor cell development GO:0042462 81 0.017
protein catabolic process GO:0030163 101 0.017
imaginal disc pattern formation GO:0007447 91 0.017
establishment of localization in cell GO:0051649 402 0.017
Worm
dna metabolic process GO:0006259 227 0.017
reproductive structure development GO:0048608 74 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.017
eye morphogenesis GO:0048592 260 0.017
cellular amine metabolic process GO:0044106 12 0.016
modification dependent macromolecule catabolic process GO:0043632 79 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
salivary gland histolysis GO:0035070 88 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
embryo development ending in birth or egg hatching GO:0009792 152 0.016
Worm
photoreceptor cell development GO:0042461 96 0.016
regulation of protein catabolic process GO:0042176 55 0.016
response to fungus GO:0009620 50 0.015
glial cell migration GO:0008347 31 0.015
negative regulation of organelle organization GO:0010639 56 0.015
nuclear transport GO:0051169 72 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
regulation of cell death GO:0010941 173 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.015
g2 dna damage checkpoint GO:0031572 69 0.015
macromolecule catabolic process GO:0009057 161 0.015
heterocycle catabolic process GO:0046700 166 0.014
apoptotic process GO:0006915 159 0.014
Worm
sensory organ precursor cell division GO:0045035 10 0.014
response to external biotic stimulus GO:0043207 293 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
immune system process GO:0002376 347 0.014
regulation of localization GO:0032879 275 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
maintenance of location GO:0051235 73 0.014
nucleobase containing compound transport GO:0015931 56 0.014
negative regulation of neurogenesis GO:0050768 53 0.014
regulation of transport GO:0051049 181 0.014
female meiotic division GO:0007143 70 0.014
g1 s transition of mitotic cell cycle GO:0000082 31 0.014
regulation of intracellular transport GO:0032386 64 0.014
histolysis GO:0007559 102 0.014
meiotic nuclear division GO:0007126 151 0.014
Worm
ribonucleoside metabolic process GO:0009119 127 0.014
regulation of mrna splicing via spliceosome GO:0048024 64 0.014
male gamete generation GO:0048232 201 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
reproductive behavior GO:0019098 122 0.014
positive regulation of developmental process GO:0051094 143 0.014
protein dna complex subunit organization GO:0071824 86 0.014
sensory organ morphogenesis GO:0090596 260 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
cellular ketone metabolic process GO:0042180 24 0.014
chromatin modification GO:0016568 147 0.013
regulation of anatomical structure morphogenesis GO:0022603 242 0.013
rna transport GO:0050658 46 0.013
regulation of hydrolase activity GO:0051336 97 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
death GO:0016265 284 0.013
Worm
embryonic morphogenesis GO:0048598 206 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
regulation of response to stress GO:0080134 200 0.013
exocrine system development GO:0035272 162 0.013
establishment of mitotic spindle localization GO:0040001 17 0.013
chromosome segregation GO:0007059 157 0.013
Worm
nucleus organization GO:0006997 45 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.013
negative regulation of chromosome segregation GO:0051985 14 0.013
regulation of cell development GO:0060284 215 0.013
ribonucleotide catabolic process GO:0009261 109 0.012
response to inorganic substance GO:0010035 44 0.012
spindle organization GO:0007051 253 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
oocyte maturation GO:0001556 3 0.012
regulation of dna metabolic process GO:0051052 34 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
regulation of kinase activity GO:0043549 53 0.012
multi organism reproductive behavior GO:0044705 121 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
ras protein signal transduction GO:0007265 88 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
multi organism behavior GO:0051705 175 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
spermatogenesis GO:0007283 200 0.012
anatomical structure homeostasis GO:0060249 97 0.012
protein phosphorylation GO:0006468 169 0.011
establishment of rna localization GO:0051236 47 0.011
positive regulation of cell cycle phase transition GO:1901989 20 0.011
neuron projection extension GO:1990138 32 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
intracellular transport GO:0046907 228 0.011
regulation of ras gtpase activity GO:0032318 38 0.011
regulation of mrna processing GO:0050684 71 0.011
regulation of developmental growth GO:0048638 174 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
establishment of cell polarity GO:0030010 40 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
kinetochore organization GO:0051383 9 0.011
rna localization GO:0006403 115 0.011
cellular protein complex assembly GO:0043623 71 0.011
sex differentiation GO:0007548 81 0.011
regulation of cellular response to stress GO:0080135 89 0.011
larval development GO:0002164 104 0.010
chemotaxis GO:0006935 249 0.010
regulation of organelle organization GO:0033043 196 0.010
Worm
homeostatic process GO:0042592 199 0.010
negative regulation of cellular metabolic process GO:0031324 382 0.010
ion transport GO:0006811 145 0.010

shtd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 0 0.029
disease of anatomical entity DOID:7 0 0.029