IMP

Process View

Drosophila melanogaster

30 genes annotated in fly

anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
CycE	Cyclin E	0.272
ida	imaginal discs arrested	0.254
Cdc37	CG12019 gene product from transcript CG12019-RA	0.193
Pp1-87B	Protein phosphatase 1 at 87B	0.183	Yeast
fzy	fizzy	0.158
ncd	non-claret disjunctional	0.152
Iswi	Imitation SWI	0.145
dup	double parked	0.124
CycA	Cyclin A	0.118
hpo	hippo	0.115
CycB	Cyclin B	0.102
cdc16	CG6759 gene product from transcript CG6759-RA	0.086
Orc2	Origin recognition complex subunit 2	0.079
flfl	falafel	0.075
Cap-G	CG34438 gene product from transcript CG34438-RF	0.069
Sse	Separase	0.066
borr	borealin-related	0.065
tefu	telomere fusion	0.061	Human
thr	three rows	0.056
east	enhanced adult sensory threshold	0.052
Vap-33-1	CG5014 gene product from transcript CG5014-RB	0.051
bam	bag of marbles	0.050
SMC2	CG10212 gene product from transcript CG10212-RA	0.050
hyd	hyperplastic discs	0.050
Aos1	CG12276 gene product from transcript CG12276-RA	0.050
nod	no distributive disjunction	0.049
asp	abnormal spindle	0.045
msps	mini spindles	0.045
Nuf2	CG8902 gene product from transcript CG8902-RA	0.043
cmet	CENP-meta	0.043
BubR1	Bub1-related kinase	0.038
Bap55	Brahma associated protein 55kD	0.037
CG8223	CG8223 gene product from transcript CG8223-RA	0.037
cdc2	CG5363 gene product from transcript CG5363-RA	0.037
NiPp1	Nuclear inhibitor of Protein phosphatase 1	0.035
brat	brain tumor	0.035
spn-D	spindle D	0.034
Su(H)	Suppressor of Hairless	0.032
RanGap	Ran GTPase activating protein	0.032
CycC	Cyclin C	0.031
lds	lodestar	0.031
nbs	CG6754 gene product from transcript CG6754-RC	0.030
kuk	kugelkern	0.029
Sce	Sex combs extra	0.029
shtd	shattered	0.028
Uch-L3	Ubiquitin C-terminal hydrolase	0.027
KP78b	CG17216 gene product from transcript CG17216-RB	0.027
sle	slender lobes	0.027
Klp61F	Kinesin-like protein at 61F	0.027
Orc6	Origin recognition complex subunit 6	0.026
prod	proliferation disrupter	0.026
betaTub56D	beta-Tubulin at 56D	0.024
I-2	Inhibitor-2	0.024
stg	string	0.024
bel	belle	0.024
polo	CG12306 gene product from transcript CG12306-RA	0.023	Human
DNApol-alpha180	DNA polymerase alpha 180kD	0.023
pie	pineapple eye	0.023
CG13625	CG13625 gene product from transcript CG13625-RA	0.023
Psf2	CG18013 gene product from transcript CG18013-RA	0.023
Mcm7	Minichromosome maintenance 7	0.023
cdc23	CG2508 gene product from transcript CG2508-RA	0.021
PPP4R2r	Protein phosphatase 4 regulatory subunit 2-related protein	0.021
brm	brahma	0.021
CG14213	CG14213 gene product from transcript CG14213-RB	0.021
Kmn1	kinetochore Mis12-Ndc80 network component 1	0.020
Mcm10	Sensitized chromosome inheritance modifier 19	0.020
cav	caravaggio	0.020
pasha	partner of drosha	0.020
drosha	CG8730 gene product from transcript CG8730-RA	0.020
nxf2	nuclear RNA export factor 2	0.020
CG8290	CG8290 gene product from transcript CG8290-RA	0.020
scra	scraps	0.020
CG15141	CG15141 gene product from transcript CG15141-RA	0.019
Nipped-A	CG33554 gene product from transcript CG33554-RE	0.019
DNApol-alpha60	DNA polymerase alpha 60kD	0.019
gammaTub23C	gamma-Tubulin at 23C	0.019
Sep2	Septin-2	0.018
CG9135	CG9135 gene product from transcript CG9135-RB	0.018
SMC1	CG6057 gene product from transcript CG6057-RA	0.018
Psa	Puromycin sensitive aminopeptidase	0.018
Kap-alpha3	karyopherin alpha3	0.018
Cks85A	Cyclin-dependent kinase subunit 85A	0.018
Tektin-A	Tektin A	0.017
CG7145	CG7145 gene product from transcript CG7145-RD	0.017
atms	antimeros	0.017
cid	centromere identifier	0.017
Rpt1	CG1341 gene product from transcript CG1341-RA	0.017
wisp	wispy	0.017
dhd	deadhead	0.016
CG13742	CG13742 gene product from transcript CG13742-RB	0.016
CG12321	CG12321 gene product from transcript CG12321-RA	0.016
gwl	greatwall	0.016
HP1e	CG8120 gene product from transcript CG8120-RA	0.016
vib	vibrator	0.016
fs(1)Ya	female sterile (1) Young arrest	0.016
Bj1	Bj1 protein	0.015
CG4119	CG4119 gene product from transcript CG4119-RA	0.015
Mov34	CG3416 gene product from transcript CG3416-RA	0.015
stau	staufen	0.015
lqf	liquid facets	0.015
TfIIS	RNA polymerase II elongation factor	0.015
Cyp18a1	Cytochrome P450-18a1	0.015
Nup153	Nucleoporin 153	0.015
Trf4-1	CG11265 gene product from transcript CG11265-RE	0.015
Rpt3	CG16916 gene product from transcript CG16916-RA	0.015
alphaTub67C	alpha-Tubulin at 67C	0.015
Hr39	Hormone receptor-like in 39	0.014
Ras85D	Ras oncogene at 85D	0.014
Lasp	CG3849 gene product from transcript CG3849-RB	0.014
pav	pavarotti	0.014
Pros54	Proteasome 54kD subunit	0.014
bond	james bond	0.014
CG9772	CG9772 gene product from transcript CG9772-RB	0.014
p53	CG33336 gene product from transcript CG33336-RB	0.014
Rpd3	CG7471 gene product from transcript CG7471-RA	0.014
Dref	DNA replication-related element factor	0.014
Ino80	CG31212 gene product from transcript CG31212-RA	0.014
Rpn9	CG10230 gene product from transcript CG10230-RB	0.014
CG7288	CG7288 gene product from transcript CG7288-RA	0.014
NELF-B	CG32721 gene product from transcript CG32721-RA	0.014
CG6439	CG6439 gene product from transcript CG6439-RA	0.014
Klp3A	Kinesin-like protein at 3A	0.013
DNApol-alpha50	DNA polymerase alpha 50kD	0.013
Pk17E	Protein kinase-like 17E	0.013
Det	Deterin	0.013
tos	tosca	0.013
CG8108	CG8108 gene product from transcript CG8108-RA	0.013
CG9238	CG9238 gene product from transcript CG9238-RA	0.013
Cenp-C	CG31258 gene product from transcript CG31258-RA	0.013
CycT	Cyclin T	0.013
abs	abstrakt	0.013
dm	diminutive	0.013
gish	gilgamesh	0.013
fwd	four wheel drive	0.013
Samuel	SAM-motif ubiquitously expressed punctatedly localized protein	0.013
CG42569	CG42569 gene product from transcript CG42569-RA	0.013
sti	sticky	0.013	Mouse
dome	domeless	0.013
Trxr-1	Thioredoxin reductase-1	0.013
Ack	CG14992 gene product from transcript CG14992-RA	0.013
CG6962	CG6962 gene product from transcript CG6962-RA	0.013
Hcf	Host cell factor	0.013
mus312	mutagen-sensitive 312	0.013
X11L	CG5675 gene product from transcript CG5675-RB	0.013
rux	roughex	0.012
pex1	peroxin 1	0.012
ana	anachronism	0.012
vtd	verthandi	0.012
CG31898	CG31898 gene product from transcript CG31898-RA	0.012
CG8965	CG8965 gene product from transcript CG8965-RA	0.012
cort	cortex	0.012
Ccp84Ab	CG1252 gene product from transcript CG1252-RA	0.012
CG2941	CG2941 gene product from transcript CG2941-RA	0.012
Myo61F	Myosin 61F	0.012
fd64A	forkhead domain 64A	0.012
Mst77F	Male-specific transcript 77F	0.012
mus304	mutagen-sensitive 304	0.012
Z600	CG17962 gene product from transcript CG17962-RA	0.012
chm	chameau	0.012
Pms2	CG8169 gene product from transcript CG8169-RA	0.012
CG7102	CG7102 gene product from transcript CG7102-RA	0.012
Acf1	ATP-dependent chromatin assembly factor large subunit	0.012
Rpb4	CG33520 gene product from transcript CG33520-RF	0.011
Rel	Relish	0.011
CG8378	CG8378 gene product from transcript CG8378-RA	0.011
Actbeta	Activin-beta	0.011
CG2926	CG2926 gene product from transcript CG2926-RA	0.011
apt	apontic	0.011
mask	multiple ankyrin repeats single KH domain	0.011
Taf2	TBP-associated factor 2	0.011
Ant2	Adenine nucleotide translocase 2	0.011
Gmd	GDP-mannose 4,6-dehydratase	0.011
CG10654	CG10654 gene product from transcript CG10654-RA	0.011
E(z)	Enhancer of zeste	0.011
mad2	CG17498 gene product from transcript CG17498-RA	0.011
cp309	CG33957 gene product from transcript CG33957-RB	0.011
thoc6	CG5632 gene product from transcript CG5632-RA	0.011
G9a	CG2995 gene product from transcript CG2995-RA	0.011
cnn	centrosomin	0.011
CG4332	CG4332 gene product from transcript CG4332-RA	0.011
Marcal1	CG3753 gene product from transcript CG3753-RA	0.011
CG13089	CG13089 gene product from transcript CG13089-RA	0.011
RpS20	Ribosomal protein S20	0.011
CG11986	CG11986 gene product from transcript CG11986-RA	0.011
Lrr47	Leucine-rich repeat 47	0.011
CG6540	CG6540 gene product from transcript CG6540-RA	0.011
CG1440	CG1440 gene product from transcript CG1440-RA	0.011
CG1104	CG1104 gene product from transcript CG1104-RB	0.011
mei-W68	meiotic W68	0.011
trol	terribly reduced optic lobes	0.011
CG10825	CG10825 gene product from transcript CG10825-RC	0.011
CG17328	CG17328 gene product from transcript CG17328-RA	0.011
Incenp	Inner centromere protein	0.010
ogre	optic ganglion reduced	0.010
krz	kurtz	0.010
zwilch	CG18729 gene product from transcript CG18729-RA	0.010
Cul-5	Cullin-5	0.010
CG8679	CG8679 gene product from transcript CG8679-RA	0.010
Pros35	Proteasome 35kD subunit	0.010
Atg6	Autophagy-specific gene 6	0.010
ial	IplI-aurora-like kinase	0.010
B-H1	BarH1	0.010
CG5872	CG5872 gene product from transcript CG5872-RA	0.010
omd	oocyte maintenance defects	0.010
Taf7	TBP-associated factor 7	0.010
asl	asterless	0.010
CG30105	CG30105 gene product from transcript CG30105-RA	0.010
kl-5	male fertility factor kl5	0.010
CG5214	CG5214 gene product from transcript CG5214-RA	0.010
Spc105R	Spc105-related	0.010