Homo sapiens

19 known processes

PAN3

PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

PAN3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.992
Yeast Mouse
nuclear transcribed mrna poly a tail shortening GO:0000289 8 0.989
Yeast
rna catabolic process GO:0006401 71 0.985
Yeast Mouse
mrna catabolic process GO:0006402 56 0.976
Yeast Mouse
mrna metabolic process GO:0016071 175 0.955
Yeast Mouse
nuclear transcribed mrna catabolic process GO:0000956 48 0.954
Yeast Mouse
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.931
rna 3 end processing GO:0031123 35 0.802
Yeast
regulation of mrna catabolic process GO:0061013 13 0.617
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.591
regulation of mrna 3 end processing GO:0031440 12 0.540
cellular macromolecule catabolic process GO:0044265 380 0.432
Yeast Mouse
protein alkylation GO:0008213 74 0.405
mrna processing GO:0006397 133 0.387
Yeast
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.364
macromolecule methylation GO:0043414 97 0.344
negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000623 3 0.315
translation GO:0006412 132 0.302
positive regulation of mrna 3 end processing GO:0031442 12 0.301
mrna 3 end processing GO:0031124 24 0.284
Yeast
translational initiation GO:0006413 48 0.264
positive regulation of mrna metabolic process GO:1903313 19 0.259
rna phosphodiester bond hydrolysis GO:0090501 35 0.249
rna processing GO:0006396 255 0.225
Yeast
protein methylation GO:0006479 74 0.215
positive regulation of cellular catabolic process GO:0031331 284 0.197
regulation of translation GO:0006417 89 0.196
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.193
posttranscriptional regulation of gene expression GO:0010608 213 0.189
cellular ketone metabolic process GO:0042180 80 0.187
histone lysine methylation GO:0034968 50 0.172
methylation GO:0032259 106 0.164
covalent chromatin modification GO:0016569 254 0.160
regulation of gene expression epigenetic GO:0040029 73 0.156
negative regulation of cellular protein metabolic process GO:0032269 353 0.152
positive regulation of catabolic process GO:0009896 310 0.151
cellular amino acid metabolic process GO:0006520 116 0.148
positive regulation of mrna processing GO:0050685 17 0.143
chromatin organization GO:0006325 351 0.135
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 8 0.131
postreplication repair GO:0006301 12 0.129
Yeast
gene silencing GO:0016458 49 0.126
memory GO:0007613 3 0.124
determination of adult lifespan GO:0008340 2 0.121
post embryonic development GO:0009791 2 0.116
hemopoiesis GO:0030097 180 0.116
peptidyl lysine methylation GO:0018022 37 0.109
regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000622 3 0.102
regulation of cellular amine metabolic process GO:0033238 11 0.102
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.100
gene silencing by mirna GO:0035195 23 0.099
negative regulation of protein metabolic process GO:0051248 391 0.099
mrna cleavage involved in gene silencing by mirna GO:0035279 2 0.098
multicellular organismal aging GO:0010259 3 0.097
gene silencing by rna GO:0031047 26 0.092
negative regulation of mrna catabolic process GO:1902373 4 0.092
negative regulation of translation GO:0017148 37 0.091
cellular amine metabolic process GO:0044106 41 0.089
chromatin modification GO:0016568 298 0.088
positive regulation of mrna catabolic process GO:0061014 10 0.087
nucleotide catabolic process GO:0009166 408 0.086
production of small rna involved in gene silencing by rna GO:0070918 13 0.084
histone acetylation GO:0016573 93 0.082
regulation of translational initiation GO:0006446 24 0.079
purine containing compound catabolic process GO:0072523 411 0.078
cellular macromolecular complex assembly GO:0034622 324 0.074
Mouse
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.072
regulation of cellular ketone metabolic process GO:0010565 50 0.068
posttranscriptional gene silencing by rna GO:0035194 25 0.064
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.060
segmentation GO:0035282 4 0.058
peptidyl lysine acetylation GO:0018394 101 0.055
protein acylation GO:0043543 138 0.055
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.054
cellular response to dna damage stimulus GO:0006974 379 0.054
Yeast
histone modification GO:0016570 251 0.054
immune system development GO:0002520 195 0.053
purine nucleoside monophosphate catabolic process GO:0009128 158 0.052
heart development GO:0007507 95 0.051
ncrna metabolic process GO:0034660 108 0.050
regulation of mrna processing GO:0050684 48 0.050
ribonucleoside triphosphate metabolic process GO:0009199 412 0.049
growth GO:0040007 202 0.049
purine ribonucleotide catabolic process GO:0009154 404 0.049
positive regulation of protein phosphorylation GO:0001934 313 0.048
negative regulation of multicellular organismal process GO:0051241 317 0.047
regulation of mrna metabolic process GO:1903311 53 0.046
purine nucleotide catabolic process GO:0006195 405 0.045
nucleoside triphosphate catabolic process GO:0009143 394 0.044
protein acetylation GO:0006473 116 0.044
immune effector process GO:0002252 159 0.044
histone h4 acetylation GO:0043967 47 0.043
negative regulation of rna catabolic process GO:1902369 4 0.042
ribonucleoside triphosphate catabolic process GO:0009203 391 0.040
organelle assembly GO:0070925 176 0.039
Mouse
apoptotic signaling pathway GO:0097190 268 0.039
histone methylation GO:0016571 60 0.038
internal protein amino acid acetylation GO:0006475 101 0.038
cellular response to external stimulus GO:0071496 111 0.037
reproductive process GO:0022414 106 0.037
purine nucleoside triphosphate metabolic process GO:0009144 412 0.036
amine metabolic process GO:0009308 44 0.036
ribonucleoprotein complex assembly GO:0022618 78 0.035
Mouse
nucleoside phosphate catabolic process GO:1901292 412 0.035
ribonucleoprotein complex biogenesis GO:0022613 116 0.034
Mouse
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.034
positive regulation of translation GO:0045727 35 0.034
peptidyl lysine modification GO:0018205 144 0.033
ribonucleotide catabolic process GO:0009261 405 0.033
myeloid cell differentiation GO:0030099 117 0.033
regulation of cellular component biogenesis GO:0044087 281 0.032
Mouse
cardiovascular system development GO:0072358 262 0.032
negative regulation of catalytic activity GO:0043086 335 0.032
protein dna complex subunit organization GO:0071824 80 0.032
purine nucleoside catabolic process GO:0006152 398 0.032
positive regulation of organelle organization GO:0010638 195 0.031
Mouse
regulation of protein stability GO:0031647 87 0.031
mitotic cell cycle process GO:1903047 286 0.031
cellular response to nutrient levels GO:0031669 69 0.031
negative regulation of translation ncrna mediated GO:0040033 6 0.030
regulation of defense response GO:0031347 154 0.030
rna interference GO:0016246 4 0.029
purine nucleoside triphosphate catabolic process GO:0009146 392 0.029
ribonucleoprotein complex subunit organization GO:0071826 81 0.029
Mouse
positive regulation of cellular amine metabolic process GO:0033240 7 0.028
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
histone h4 k5 acetylation GO:0043981 15 0.027
regulation of nucleotide metabolic process GO:0006140 269 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.027
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.027
negative regulation of immune system process GO:0002683 136 0.027
neurological system process GO:0050877 163 0.026
negative regulation of translation involved in gene silencing by mirna GO:0035278 6 0.026
long term synaptic potentiation GO:0060291 1 0.026
regulation of proteolysis GO:0030162 293 0.025
ras protein signal transduction GO:0007265 73 0.025
negative regulation of cellular amine metabolic process GO:0033239 3 0.025
purine ribonucleoside catabolic process GO:0046130 398 0.025
nucleoside monophosphate catabolic process GO:0009125 159 0.025
posttranscriptional gene silencing GO:0016441 25 0.025
response to organic cyclic compound GO:0014070 204 0.024
regulation of cell cycle process GO:0010564 266 0.024
cellular response to starvation GO:0009267 58 0.024
regulation of translation ncrna mediated GO:0045974 6 0.024
positive regulation of cellular component organization GO:0051130 376 0.024
Mouse
morphogenesis of embryonic epithelium GO:0016331 4 0.023
anatomical structure formation involved in morphogenesis GO:0048646 284 0.023
nucleoside catabolic process GO:0009164 408 0.023
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.023
organophosphate catabolic process GO:0046434 430 0.022
mitotic cell cycle GO:0000278 326 0.022
negative regulation of cell death GO:0060548 345 0.022
endocytosis GO:0006897 159 0.022
positive regulation of cell death GO:0010942 263 0.022
response to external biotic stimulus GO:0043207 261 0.022
dephosphorylation GO:0016311 209 0.022
dna repair GO:0006281 198 0.022
Yeast
atp catabolic process GO:0006200 157 0.022
ribonucleoside catabolic process GO:0042454 406 0.022
ncrna catabolic process GO:0034661 14 0.022
defense response GO:0006952 315 0.021
regulation of response to external stimulus GO:0032101 222 0.021
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.021
aging GO:0007568 66 0.021
immune response GO:0006955 307 0.021
regulation of cellular response to stress GO:0080135 244 0.021
purine ribonucleoside metabolic process GO:0046128 437 0.021
cell cycle checkpoint GO:0000075 117 0.021
negative regulation of transport GO:0051051 176 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
negative regulation of catabolic process GO:0009895 104 0.020
cellular response to nitrogen compound GO:1901699 144 0.020
regulation of myeloid cell differentiation GO:0045637 81 0.020
response to biotic stimulus GO:0009607 276 0.020
negative regulation of protein modification process GO:0031400 200 0.020
blastoderm segmentation GO:0007350 2 0.019
response to lipid GO:0033993 206 0.019
regulation of purine nucleotide metabolic process GO:1900542 264 0.019
mitotic nuclear division GO:0007067 119 0.019
vesicle mediated transport GO:0016192 371 0.019
ribonucleoside monophosphate catabolic process GO:0009158 158 0.019
cellular response to extracellular stimulus GO:0031668 72 0.019
peptidyl lysine trimethylation GO:0018023 10 0.018
system process GO:0003008 349 0.018
actin filament based process GO:0030029 224 0.018
positive regulation of phosphorylation GO:0042327 394 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.018
cytokine production GO:0001816 247 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
salivary gland morphogenesis GO:0007435 4 0.018
nucleoside triphosphate metabolic process GO:0009141 422 0.018
positive regulation of cell proliferation GO:0008284 301 0.018
protein ubiquitination GO:0016567 314 0.017
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
protein processing GO:0016485 226 0.017
regulation of immune effector process GO:0002697 91 0.017
cellular response to oxygen containing compound GO:1901701 276 0.017
internal peptidyl lysine acetylation GO:0018393 97 0.017
negative regulation of chromatin silencing GO:0031936 4 0.017
regulation of synaptic plasticity GO:0048167 3 0.017
nucleoside monophosphate metabolic process GO:0009123 191 0.017
glycoprotein metabolic process GO:0009100 110 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
sensory perception of mechanical stimulus GO:0050954 37 0.016
protein catabolic process GO:0030163 325 0.016
regulation of dephosphorylation GO:0035303 96 0.016
regulation of response to biotic stimulus GO:0002831 55 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
reactive oxygen species metabolic process GO:0072593 75 0.016
amino sugar metabolic process GO:0006040 15 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
protein modification by small protein conjugation GO:0032446 342 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
modification dependent macromolecule catabolic process GO:0043632 212 0.015
negative regulation of endopeptidase activity GO:0010951 84 0.015
cell morphogenesis GO:0000902 296 0.015
protein oligomerization GO:0051259 173 0.015
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.015
pre mirna processing GO:0031054 8 0.015
reactive oxygen species biosynthetic process GO:1903409 4 0.015
chromosome segregation GO:0007059 114 0.014
oogenesis GO:0048477 2 0.014
regulation of growth GO:0040008 165 0.014
regulation of cell differentiation GO:0045595 393 0.014
positive regulation of programmed cell death GO:0043068 249 0.014
response to starvation GO:0042594 59 0.014
behavior GO:0007610 112 0.014
response to other organism GO:0051707 261 0.014
spermatid differentiation GO:0048515 4 0.014
purine nucleoside monophosphate metabolic process GO:0009126 186 0.014
protein maturation GO:0051604 233 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
glycosyl compound catabolic process GO:1901658 413 0.013
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.013
regulation of immune response GO:0050776 201 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
organ morphogenesis GO:0009887 147 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
histone h4 k16 acetylation GO:0043984 14 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
female gamete generation GO:0007292 2 0.013
regulation of ras protein signal transduction GO:0046578 155 0.013
cytoplasmic mrna processing body assembly GO:0033962 10 0.013
Mouse
negative regulation of multi organism process GO:0043901 92 0.013
regulation of gtpase activity GO:0043087 180 0.013
glycosylation GO:0070085 71 0.013
cellular response to lipid GO:0071396 127 0.013
protein autophosphorylation GO:0046777 123 0.013
regulation of protein maturation GO:1903317 150 0.013
myosin filament assembly GO:0031034 2 0.012
transcription initiation from rna polymerase ii promoter GO:0006367 27 0.012
regulation of multi organism process GO:0043900 157 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.012
negative regulation of apoptotic signaling pathway GO:2001234 97 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
single organism cellular localization GO:1902580 332 0.012
sensory perception GO:0007600 103 0.012
receptor mediated endocytosis GO:0006898 84 0.012
motor neuron axon guidance GO:0008045 2 0.012
small gtpase mediated signal transduction GO:0007264 78 0.012
reproductive system development GO:0061458 56 0.012
sensory perception of sound GO:0007605 37 0.012
dna damage checkpoint GO:0000077 68 0.012
maintenance of location GO:0051235 112 0.012
negative regulation of cell cycle GO:0045786 193 0.012
atp metabolic process GO:0046034 176 0.012
embryonic organ development GO:0048568 36 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
circulatory system development GO:0072359 262 0.011
peptidyl tyrosine phosphorylation GO:0018108 170 0.011
defense response to other organism GO:0098542 129 0.011
regulation of intracellular transport GO:0032386 195 0.011
cerebellum development GO:0021549 2 0.011
guanosine containing compound catabolic process GO:1901069 239 0.011
rna splicing GO:0008380 131 0.011
response to growth factor GO:0070848 205 0.011
toll signaling pathway GO:0008063 2 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
regulation of protein kinase activity GO:0045859 289 0.011
myosin filament organization GO:0031033 2 0.011
regulation of gene silencing GO:0060968 24 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
neural tube formation GO:0001841 3 0.011
single organism reproductive process GO:0044702 98 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
negative regulation of programmed cell death GO:0043069 321 0.010
oxidation reduction process GO:0055114 396 0.010
lipid localization GO:0010876 106 0.010
innate immune response GO:0045087 178 0.010
gtp catabolic process GO:0006184 237 0.010
regulation of cell cycle GO:0051726 393 0.010
metencephalon development GO:0022037 2 0.010
negative regulation of developmental process GO:0051093 247 0.010
negative regulation of phosphorylation GO:0042326 174 0.010

PAN3 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.052
nervous system disease DOID:863 431 0.052
neurodegenerative disease DOID:1289 102 0.019
disease of cellular proliferation DOID:14566 174 0.013
immune system disease DOID:2914 155 0.012
hematopoietic system disease DOID:74 100 0.012
musculoskeletal system disease DOID:17 223 0.010
connective tissue disease DOID:65 109 0.010