Homo sapiens

245 known processes

PDGFA

platelet-derived growth factor alpha polypeptide

(Aliases: PDGF1,PDGF-A)

PDGFA biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
angiogenesis involved in wound healing GO:0060055 4 0.977
Human
cell migration involved in metanephros development GO:0035788 2 0.974
vascular wound healing GO:0061042 4 0.932
Human
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 0.894
Human
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 2 0.876
metanephric mesenchymal cell migration GO:0035789 2 0.875
glomerular mesangial cell proliferation GO:0072110 3 0.863
Human
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 2 0.863
cell migration involved in kidney development GO:0035787 2 0.862
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 0.859
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway GO:0038091 3 0.826
Human
positive regulation of metanephric mesenchymal cell migration GO:2000591 2 0.816
retina vasculature development in camera type eye GO:0061298 3 0.816
regulation of glomerulus development GO:0090192 3 0.770
Human
cell proliferation involved in kidney development GO:0072111 3 0.671
Human
positive regulation of metanephros development GO:0072216 3 0.649
metanephric nephron development GO:0072210 9 0.596
negative regulation of blood coagulation GO:0030195 22 0.583
cellular response to macrophage colony stimulating factor stimulus GO:0036006 4 0.567
metanephric glomerulus vasculature development GO:0072239 1 0.537
regulation of cellular ketone metabolic process GO:0010565 50 0.537
positive regulation of histone deacetylase activity GO:1901727 3 0.529
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.525
regulation of metanephric mesenchymal cell migration GO:2000589 2 0.522
cell cell junction maintenance GO:0045217 4 0.489
glomerulus development GO:0032835 15 0.487
Human
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway GO:0038033 4 0.480
Human
negative regulation of hemostasis GO:1900047 22 0.477
positive regulation of mast cell chemotaxis GO:0060754 4 0.472
Human
kidney vasculature morphogenesis GO:0061439 1 0.471
positive regulation of glomerular mesangial cell proliferation GO:0072126 1 0.462
Human
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.443
negative regulation of phosphatidylinositol biosynthetic process GO:0010512 2 0.412
anatomical structure formation involved in morphogenesis GO:0048646 284 0.400
Human Mouse
regulation of cellular amine metabolic process GO:0033238 11 0.386
positive regulation of peptidyl tyrosine autophosphorylation GO:1900086 1 0.383
Human
salivary gland morphogenesis GO:0007435 4 0.378
Mouse
vascular endothelial growth factor receptor 1 signaling pathway GO:0036323 1 0.375
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.357
regulation of mast cell chemotaxis GO:0060753 4 0.356
Human
regulation of vascular wound healing GO:0061043 2 0.355
Human
cellular ketone metabolic process GO:0042180 80 0.352
regulation of adherens junction organization GO:1903391 21 0.352
Human
vasculature development GO:0001944 181 0.351
Human Mouse
positive regulation of vascular wound healing GO:0035470 1 0.337
Human
cardiac myofibril assembly GO:0055003 3 0.320
positive regulation of protein kinase c signaling GO:0090037 5 0.319
Human
endocrine system development GO:0035270 26 0.318
positive regulation of cellular amine metabolic process GO:0033240 7 0.302
cellular amine metabolic process GO:0044106 41 0.301
cardiac muscle tissue development GO:0048738 39 0.290
cellular response to endogenous stimulus GO:0071495 336 0.289
renal system vasculature morphogenesis GO:0061438 1 0.288
amine metabolic process GO:0009308 44 0.286
positive regulation of endothelial cell proliferation GO:0001938 37 0.275
Human
muscle cell proliferation GO:0033002 35 0.266
Human
blood vessel morphogenesis GO:0048514 162 0.266
Human Mouse
metanephric glomerulus development GO:0072224 2 0.264
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.262
branching involved in salivary gland morphogenesis GO:0060445 1 0.261
Mouse
cellular response to organonitrogen compound GO:0071417 124 0.257
renal system process involved in regulation of blood volume GO:0001977 4 0.257
positive regulation of focal adhesion assembly GO:0051894 11 0.255
Human
rho protein signal transduction GO:0007266 26 0.253
regulation of angiogenesis GO:0045765 92 0.246
Human
cardiovascular system development GO:0072358 262 0.243
Human Mouse
cellular response to oxygen containing compound GO:1901701 276 0.237
positive regulation of protein phosphorylation GO:0001934 313 0.233
mast cell cytokine production GO:0032762 1 0.228
lipid metabolic process GO:0006629 381 0.226
ameboidal type cell migration GO:0001667 135 0.225
Human
response to increased oxygen levels GO:0036296 4 0.223
organ morphogenesis GO:0009887 147 0.221
Mouse
cell junction maintenance GO:0034331 4 0.221
male genitalia development GO:0030539 1 0.219
cellular amino acid metabolic process GO:0006520 116 0.213
tube development GO:0035295 125 0.213
Human Mouse
phosphatidylinositol metabolic process GO:0046488 53 0.213
mast cell degranulation GO:0043303 4 0.212
regulation of smooth muscle cell proliferation GO:0048660 28 0.211
Human
monocyte chemotaxis GO:0002548 20 0.208
Human
regulation of cell matrix adhesion GO:0001952 42 0.207
Human
cyclic nucleotide metabolic process GO:0009187 82 0.206
Human
response to macrophage colony stimulating factor GO:0036005 4 0.203
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.202
regulation of lipid kinase activity GO:0043550 19 0.200
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.199
positive regulation of endothelial cell migration GO:0010595 39 0.196
Human
negative regulation of multicellular organismal process GO:0051241 317 0.196
glomerulus vasculature development GO:0072012 6 0.196
Human
regulation of cell migration GO:0030334 289 0.195
positive regulation of dna replication GO:0045740 35 0.195
activation of protein kinase activity GO:0032147 90 0.193
Human
focal adhesion assembly GO:0048041 30 0.191
Human
positive regulation of fibroblast proliferation GO:0048146 21 0.189
response to abiotic stimulus GO:0009628 336 0.189
Human
fibroblast proliferation GO:0048144 33 0.188
basophil chemotaxis GO:0002575 1 0.188
Human
cell projection organization GO:0030030 252 0.186
Mouse
regulation of transferase activity GO:0051338 355 0.185
metanephros development GO:0001656 16 0.185
smooth muscle cell proliferation GO:0048659 28 0.182
Human
negative regulation of coagulation GO:0050819 24 0.181
regulation of kinase activity GO:0043549 314 0.181
angiogenesis GO:0001525 147 0.181
Human Mouse
cell substrate adhesion GO:0031589 132 0.178
Human
cellular response to amino acid stimulus GO:0071230 12 0.177
response to stem cell factor GO:0036215 1 0.177
fc receptor signaling pathway GO:0038093 2 0.176
muscle structure development GO:0061061 98 0.175
positive regulation of developmental process GO:0051094 314 0.174
epithelium migration GO:0090132 119 0.174
Human
circulatory system development GO:0072359 262 0.170
Human Mouse
enzyme linked receptor protein signaling pathway GO:0007167 303 0.167
wound healing GO:0042060 115 0.164
positive regulation of phosphorylation GO:0042327 394 0.162
positive regulation of cell proliferation GO:0008284 301 0.162
cellular lipid metabolic process GO:0044255 303 0.159
regulation of peptidyl tyrosine autophosphorylation GO:1900084 1 0.158
Human
actin cytoskeleton organization GO:0030036 207 0.154
Mouse
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.154
negative regulation of gastrulation GO:2000542 4 0.151
lipid biosynthetic process GO:0008610 177 0.149
cell adhesion GO:0007155 325 0.147
Human
regulation of cell motility GO:2000145 299 0.143
regulation of locomotion GO:0040012 329 0.143
heart development GO:0007507 95 0.140
digestive system development GO:0055123 75 0.139
Mouse
response to hyperoxia GO:0055093 4 0.137
cytokine mediated signaling pathway GO:0019221 109 0.133
cell substrate adherens junction assembly GO:0007045 30 0.133
Human
cellular response to nitrogen compound GO:1901699 144 0.132
small gtpase mediated signal transduction GO:0007264 78 0.132
cardiocyte differentiation GO:0035051 23 0.132
negative regulation of cell death GO:0060548 345 0.131
Human
smooth muscle cell migration GO:0014909 18 0.131
carbohydrate derivative biosynthetic process GO:1901137 207 0.131
Human
positive regulation of transferase activity GO:0051347 227 0.130
urogenital system development GO:0001655 65 0.128
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.128
divalent inorganic cation transport GO:0072511 158 0.127
Human
endothelial cell migration GO:0043542 86 0.127
Human
glycerophospholipid metabolic process GO:0006650 84 0.127
response to acid chemical GO:0001101 66 0.126
regulation of epithelial cell migration GO:0010632 93 0.126
Human
positive regulation of epithelial cell proliferation GO:0050679 65 0.125
Human
response to organonitrogen compound GO:0010243 156 0.125
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.124
Human
cell chemotaxis GO:0060326 112 0.124
Human
formation of primary germ layer GO:0001704 42 0.123
cell matrix adhesion GO:0007160 85 0.123
Human
aminoglycan biosynthetic process GO:0006023 29 0.122
Human
organelle assembly GO:0070925 176 0.121
protein kinase c signaling GO:0070528 17 0.120
Human
gastrulation GO:0007369 51 0.120
positive regulation of immune system process GO:0002684 283 0.118
Human
tissue migration GO:0090130 119 0.118
Human
cardiac muscle cell differentiation GO:0055007 15 0.117
adherens junction organization GO:0034332 36 0.117
Human
cellular response to acid chemical GO:0071229 44 0.117
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.116
Human
positive regulation of protein kinase activity GO:0045860 190 0.116
dephosphorylation GO:0016311 209 0.115
regulation of proteolysis GO:0030162 293 0.115
Human
blood vessel development GO:0001568 172 0.115
Human Mouse
positive regulation of cell motility GO:2000147 177 0.114
mucopolysaccharide metabolic process GO:1903510 27 0.114
Human
regulation of cell substrate adhesion GO:0010810 68 0.114
Human
positive regulation of locomotion GO:0040017 186 0.113
positive regulation of kinase activity GO:0033674 204 0.112
response to cytokine GO:0034097 232 0.111
biological adhesion GO:0022610 331 0.110
Human
regulation of coagulation GO:0050818 44 0.110
regulation of nucleotide metabolic process GO:0006140 269 0.108
Human
cation transport GO:0006812 331 0.108
Human
glycerolipid metabolic process GO:0046486 107 0.108
response to growth factor GO:0070848 205 0.108
Human
regulation of mapk cascade GO:0043408 262 0.106
regulation of protein kinase c signaling GO:0090036 8 0.106
Human
estrogen metabolic process GO:0008210 6 0.104
negative regulation of programmed cell death GO:0043069 321 0.104
Human
mast cell activation involved in immune response GO:0002279 4 0.103
cell development GO:0048468 328 0.103
calcium ion import GO:0070509 23 0.103
Human
patterning of blood vessels GO:0001569 2 0.103
apoptotic signaling pathway GO:0097190 268 0.102
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.102
glycerolipid biosynthetic process GO:0045017 51 0.102
negative regulation of apoptotic process GO:0043066 316 0.101
Human
positive regulation of ion transmembrane transport GO:0034767 40 0.101
Human
metal ion transport GO:0030001 272 0.099
Human
hemopoiesis GO:0030097 180 0.099
Human
cellular response to abiotic stimulus GO:0071214 117 0.097
positive regulation of cellular component organization GO:0051130 376 0.096
Human
negative regulation of catalytic activity GO:0043086 335 0.096
Human
activation of transmembrane receptor protein tyrosine kinase activity GO:0007171 4 0.096
muscle cell differentiation GO:0042692 63 0.096
endochondral bone morphogenesis GO:0060350 3 0.094
regulation of peptidase activity GO:0052547 180 0.094
Human
regulation of canonical wnt signaling pathway GO:0060828 88 0.094
epithelial cell migration GO:0010631 119 0.093
Human
regulation of vascular endothelial growth factor receptor signaling pathway GO:0030947 9 0.093
Human
negative regulation of developmental process GO:0051093 247 0.092
kit signaling pathway GO:0038109 1 0.092
positive regulation of stress activated mapk cascade GO:0032874 60 0.092
Human
leukocyte migration GO:0050900 107 0.091
Human
positive regulation of mitosis GO:0045840 25 0.090
Human
regulation of cell adhesion GO:0030155 166 0.090
Human
digestive tract morphogenesis GO:0048546 56 0.089
regeneration GO:0031099 4 0.089
regulation of transmembrane transport GO:0034762 139 0.089
Human
negative regulation of locomotion GO:0040013 118 0.089
regulation of cell morphogenesis GO:0022604 153 0.088
Human
positive regulation of calcium ion transport GO:0051928 51 0.088
Human
striated muscle cell differentiation GO:0051146 43 0.087
regulation of cell substrate junction assembly GO:0090109 20 0.086
Human
regulation of protein kinase activity GO:0045859 289 0.086
purine nucleoside triphosphate catabolic process GO:0009146 392 0.086
aorta morphogenesis GO:0035909 1 0.084
mitotic cell cycle GO:0000278 326 0.083
Human
response to oxygen containing compound GO:1901700 369 0.083
dna biosynthetic process GO:0071897 40 0.083
Human
cellular response to cytokine stimulus GO:0071345 181 0.083
regulation of vasculature development GO:1901342 97 0.083
Human
vesicle mediated transport GO:0016192 371 0.083
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.082
Human Mouse
muscle cell development GO:0055001 29 0.082
negative regulation of response to wounding GO:1903035 47 0.082
regulation of anatomical structure morphogenesis GO:0022603 286 0.082
Human Mouse
muscle tissue development GO:0060537 62 0.082
mitotic spindle elongation GO:0000022 4 0.082
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 0.082
Human
positive regulation of lipase activity GO:0060193 28 0.082
response to nitrogen compound GO:1901698 184 0.082
regulation of response to external stimulus GO:0032101 222 0.082
ossification GO:0001503 121 0.082
regulation of stem cell differentiation GO:2000736 56 0.081
tube morphogenesis GO:0035239 95 0.081
Human
hemostasis GO:0007599 76 0.081
regulation of reactive oxygen species metabolic process GO:2000377 41 0.081
Human
mast cell chemotaxis GO:0002551 5 0.081
Human
myeloid leukocyte migration GO:0097529 62 0.080
Human
actin filament based process GO:0030029 224 0.079
Mouse
positive regulation of cell division GO:0051781 59 0.079
Human
platelet activation GO:0030168 44 0.079
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.079
Human
single organism cellular localization GO:1902580 332 0.079
response to radiation GO:0009314 151 0.078
endoderm formation GO:0001706 33 0.077
ribonucleoside triphosphate metabolic process GO:0009199 412 0.076
positive regulation of cell junction assembly GO:1901890 11 0.076
Human
dna replication GO:0006260 116 0.076
coagulation GO:0050817 78 0.075
mapk cascade GO:0000165 288 0.075
regulation of blood coagulation GO:0030193 42 0.075
system process GO:0003008 349 0.075
Human
digestive tract development GO:0048565 75 0.074
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.074
Human
peptidyl serine modification GO:0018209 106 0.074
Human
cell morphogenesis GO:0000902 296 0.074
Human
nervous system development GO:0007399 293 0.073
regulation of secretion GO:0051046 194 0.073
protein localization to early endosome GO:1902946 2 0.073
Human
positive regulation of cell cycle GO:0045787 140 0.073
Human
immune response GO:0006955 307 0.073
cell junction organization GO:0034330 79 0.073
Human
cell cell signaling GO:0007267 155 0.073
Mouse
response to lipid GO:0033993 206 0.072
response to mechanical stimulus GO:0009612 51 0.072
regulation of endodermal cell differentiation GO:1903224 3 0.072
cellular response to stem cell factor stimulus GO:0036216 1 0.072
regulation of endothelial cell proliferation GO:0001936 56 0.072
Human
myeloid leukocyte cytokine production GO:0061082 5 0.072
carbohydrate metabolic process GO:0005975 207 0.071
Human
regulation of epithelial cell proliferation GO:0050678 113 0.071
Human
regulation of cellular component movement GO:0051270 334 0.071
organ formation GO:0048645 3 0.071
protein localization to organelle GO:0033365 280 0.071
Human
growth GO:0040007 202 0.071
positive regulation of cell migration GO:0030335 172 0.070
regulation of protein serine threonine kinase activity GO:0071900 179 0.070
regulation of mitotic cell cycle GO:0007346 189 0.070
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.070
Human
regulation of blood vessel endothelial cell migration GO:0043535 30 0.070
Human
negative chemotaxis GO:0050919 11 0.069
soft palate development GO:0060023 3 0.068
ribonucleoside triphosphate catabolic process GO:0009203 391 0.068
single organismal cell cell adhesion GO:0016337 148 0.068
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.068
regulation of protein localization GO:0032880 296 0.068
Human
embryonic placenta development GO:0001892 1 0.068
mesenchymal cell differentiation GO:0048762 52 0.067
positive regulation of transport GO:0051050 336 0.067
Human
cell substrate junction assembly GO:0007044 35 0.067
Human
positive regulation of hydrolase activity GO:0051345 331 0.067
Human
regulation of cell cycle process GO:0010564 266 0.066
Human
cellular response to organic cyclic compound GO:0071407 127 0.066
ras protein signal transduction GO:0007265 73 0.066
purine ribonucleotide catabolic process GO:0009154 404 0.066
regulation of focal adhesion assembly GO:0051893 20 0.066
Human
epithelial cell proliferation GO:0050673 128 0.066
Human
response to inorganic substance GO:0010035 127 0.065
positive regulation of cell adhesion GO:0045785 84 0.065
Human
mesangial cell development GO:0072143 1 0.065
cellular component morphogenesis GO:0032989 314 0.065
Human
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.064
regulation of cell junction assembly GO:1901888 29 0.064
Human
cell activation GO:0001775 213 0.064
adherens junction assembly GO:0034333 34 0.064
Human
cellular response to growth factor stimulus GO:0071363 197 0.064
Human
second messenger mediated signaling GO:0019932 78 0.063
regulation of dna metabolic process GO:0051052 153 0.063
cell growth GO:0016049 160 0.063
nephron development GO:0072006 30 0.063
Human
central nervous system development GO:0007417 123 0.063
extrinsic apoptotic signaling pathway GO:0097191 119 0.063
response to amino acid GO:0043200 14 0.063
purine nucleotide catabolic process GO:0006195 405 0.062
regulation of hemostasis GO:1900046 42 0.062
reactive oxygen species metabolic process GO:0072593 75 0.062
Human
regulation of stress activated mapk cascade GO:0032872 84 0.062
Human
erk1 and erk2 cascade GO:0070371 104 0.062
regulation of histone deacetylase activity GO:1901725 3 0.062
Human
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.062
Human
microtubule cytoskeleton organization GO:0000226 176 0.062
actin filament organization GO:0007015 128 0.062
mitotic cell cycle process GO:1903047 286 0.061
Human
cell migration involved in sprouting angiogenesis GO:0002042 19 0.061
Human
positive regulation of chemotaxis GO:0050921 57 0.061
Human
positive regulation of cell cycle process GO:0090068 106 0.061
Human
response to wounding GO:0009611 168 0.061
microtubule based process GO:0007017 210 0.061
post embryonic development GO:0009791 2 0.060
striated muscle tissue development GO:0014706 59 0.060
negative regulation of endodermal cell differentiation GO:1903225 2 0.060
heart morphogenesis GO:0003007 48 0.060
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.059
cellular component assembly involved in morphogenesis GO:0010927 73 0.059
regulation of cell migration involved in sprouting angiogenesis GO:0090049 9 0.058
Human
granulocyte migration GO:0097530 40 0.058
Human
regulation of mesenchymal stem cell differentiation GO:2000739 6 0.058
myeloid cell differentiation GO:0030099 117 0.058
Human
wnt signaling pathway GO:0016055 156 0.058
connective tissue development GO:0061448 39 0.058
Human
regulation of wound healing GO:0061041 56 0.058
histone deacetylation GO:0016575 32 0.057
Human
cellular response to dna damage stimulus GO:0006974 379 0.057
regulation of cellular response to stress GO:0080135 244 0.057
Human
segmentation GO:0035282 4 0.057
metanephric s shaped body morphogenesis GO:0072284 4 0.057
skeletal system morphogenesis GO:0048705 24 0.057
gland morphogenesis GO:0022612 8 0.056
Mouse
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.056
Human
protein autophosphorylation GO:0046777 123 0.056
regulation of cellular response to growth factor stimulus GO:0090287 76 0.055
Human
morphogenesis of a branching structure GO:0001763 21 0.055
Mouse
gland development GO:0048732 48 0.054
Mouse
spindle elongation GO:0051231 4 0.054
regulation of cell differentiation GO:0045595 393 0.054
sprouting angiogenesis GO:0002040 29 0.054
Human
chromatin modification GO:0016568 298 0.054
Human
positive regulation of behavior GO:0048520 60 0.054
Human
smooth muscle cell chemotaxis GO:0071670 2 0.054
positive regulation of cellular component biogenesis GO:0044089 158 0.053
Human
regulation of lipid metabolic process GO:0019216 96 0.053
lymphangiogenesis GO:0001946 7 0.052
positive regulation of dna biosynthetic process GO:2000573 8 0.052
Human
purine ribonucleoside catabolic process GO:0046130 398 0.052
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.052
odontogenesis GO:0042476 25 0.052
canonical wnt signaling pathway GO:0060070 116 0.051
aminoglycan metabolic process GO:0006022 39 0.051
Human
blood coagulation GO:0007596 76 0.051
regulation of system process GO:0044057 101 0.051
negative regulation of phosphate metabolic process GO:0045936 267 0.051
regulation of phosphatidylinositol biosynthetic process GO:0010511 5 0.050
positive regulation of cell matrix adhesion GO:0001954 23 0.050
Human
positive regulation of adherens junction organization GO:1903393 12 0.050
Human
regulation of metanephros development GO:0072215 4 0.050
protein deacetylation GO:0006476 38 0.050
Human
renal system process GO:0003014 25 0.050
regulation of cellular component biogenesis GO:0044087 281 0.050
Human
immune system development GO:0002520 195 0.049
Human
regulation of endothelial cell migration GO:0010594 67 0.049
Human
regulation of cytokine production GO:0001817 232 0.049
regulation of establishment of protein localization GO:0070201 242 0.049
cardiac muscle cell development GO:0055013 5 0.049
regulation of ion transmembrane transport GO:0034765 132 0.049
Human
positive regulation of mapk cascade GO:0043410 190 0.049
positive regulation of cellular component movement GO:0051272 181 0.049
cell junction assembly GO:0034329 67 0.049
Human
response to oxygen levels GO:0070482 100 0.049
Human
embryonic morphogenesis GO:0048598 85 0.048
signal transduction by phosphorylation GO:0023014 297 0.048
response to hormone GO:0009725 175 0.048
single organism membrane organization GO:0044802 268 0.048
negative regulation of phosphorus metabolic process GO:0010563 267 0.048
regulation of protein transport GO:0051223 213 0.048
muscle cell migration GO:0014812 19 0.048
female gamete generation GO:0007292 2 0.048
regulation of behavior GO:0050795 82 0.048
Human
kidney development GO:0001822 53 0.048
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.047
Human
negative regulation of cellular protein metabolic process GO:0032269 353 0.047
Human
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.047
Human
protein maturation GO:0051604 233 0.047
Human
negative regulation of cell adhesion GO:0007162 64 0.047
cell projection assembly GO:0030031 126 0.046
Mouse
purine nucleoside catabolic process GO:0006152 398 0.046
peptidyl serine phosphorylation GO:0018105 101 0.046
Human
regulation of chemokine production GO:0032642 31 0.046
positive regulation of lipid metabolic process GO:0045834 50 0.046
Human
phospholipid biosynthetic process GO:0008654 44 0.046
negative regulation of response to external stimulus GO:0032102 83 0.046
regulation of body fluid levels GO:0050878 99 0.046
positive regulation of chemokine secretion GO:0090197 6 0.045
osteoblast differentiation GO:0001649 92 0.045
positive regulation of epithelial cell migration GO:0010634 55 0.045
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.045
Human
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.045
negative regulation of cell differentiation GO:0045596 171 0.045
negative regulation of apoptotic signaling pathway GO:2001234 97 0.045
regulation of immune response GO:0050776 201 0.044
peptidyl tyrosine modification GO:0018212 170 0.044
Human Mouse
nephron epithelium development GO:0072009 23 0.044
negative regulation of cell proliferation GO:0008285 228 0.044
cell type specific apoptotic process GO:0097285 125 0.044
Human
organophosphate catabolic process GO:0046434 430 0.044
regulation of receptor mediated endocytosis GO:0048259 32 0.044
Human
ion transmembrane transport GO:0034220 338 0.043
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.043
Human Mouse
cellular hormone metabolic process GO:0034754 41 0.043
embryo development GO:0009790 123 0.043
Mouse
cellular response to hypoxia GO:0071456 51 0.042
Human
hormone metabolic process GO:0042445 61 0.042
palate development GO:0060021 13 0.042
actomyosin structure organization GO:0031032 59 0.042
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.042
Human
negative regulation of endothelial cell apoptotic process GO:2000352 16 0.042
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.042
regulation of map kinase activity GO:0043405 108 0.042
glycosaminoglycan biosynthetic process GO:0006024 27 0.041
Human
regulation of cell cycle GO:0051726 393 0.041
Human
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.041
regulation of fibroblast proliferation GO:0048145 32 0.041
response to steroid hormone GO:0048545 80 0.041
response to organic cyclic compound GO:0014070 204 0.041
positive regulation of proteolysis GO:0045862 142 0.041
response to external biotic stimulus GO:0043207 261 0.041
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.041
Human
locomotory behavior GO:0007626 1 0.041
positive regulation of jnk cascade GO:0046330 52 0.041
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.041
Human
response to estrogen GO:0043627 47 0.041
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.040
motor neuron axon guidance GO:0008045 2 0.040
mitotic nuclear division GO:0007067 119 0.040
Human
sensory perception of light stimulus GO:0050953 35 0.040
regulation of tyrosine phosphorylation of stat1 protein GO:0042510 11 0.040
positive chemotaxis GO:0050918 33 0.040
Human
regulation of chemokine secretion GO:0090196 7 0.040
ribonucleotide catabolic process GO:0009261 405 0.040
cell division GO:0051301 168 0.040
Human
regulation of actin filament based process GO:0032970 141 0.040
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 0.040
Human
s shaped body morphogenesis GO:0072050 4 0.039
endothelial cell apoptotic process GO:0072577 26 0.039
organelle fission GO:0048285 149 0.039
Human
regulation of phosphatase activity GO:0010921 81 0.039
membrane organization GO:0061024 292 0.039
mesenchymal cell development GO:0014031 50 0.039
negative regulation of platelet activation GO:0010544 7 0.039
immune response regulating signaling pathway GO:0002764 97 0.039
tor signaling GO:0031929 39 0.038
negative regulation of lipid metabolic process GO:0045833 38 0.038
intracellular protein transport GO:0006886 270 0.038
regulation of actin cytoskeleton organization GO:0032956 116 0.038
divalent metal ion transport GO:0070838 152 0.038
Human
kidney epithelium development GO:0072073 25 0.038
blood vessel endothelial cell migration GO:0043534 42 0.038
Human
chordate embryonic development GO:0043009 34 0.037
negative regulation of hydrolase activity GO:0051346 182 0.037
Human
head development GO:0060322 108 0.037
metanephric comma shaped body morphogenesis GO:0072278 2 0.037
regulation of nuclear division GO:0051783 65 0.037
Human
cytoplasmic transport GO:0016482 379 0.037
organonitrogen compound biosynthetic process GO:1901566 200 0.037
Human
divalent inorganic cation homeostasis GO:0072507 136 0.037

PDGFA disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.108
Human
musculoskeletal system disease DOID:17 223 0.107
connective tissue disease DOID:65 109 0.107
cancer DOID:162 167 0.104
Human
organ system cancer DOID:0050686 164 0.104
Human
osteochondrodysplasia DOID:2256 35 0.087
bone development disease DOID:0080006 55 0.087
bone disease DOID:0080001 88 0.087