|
|
mesendoderm development
|
GO:0048382 |
1 |
1.000
|
|
|
|
anatomical structure regression
|
GO:0060033 |
1 |
1.000
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
1.000
|
Mouse |
|
|
regulation of pathway restricted smad protein phosphorylation
|
GO:0060393 |
34 |
1.000
|
|
|
|
regulation of activin receptor signaling pathway
|
GO:0032925 |
14 |
1.000
|
|
|
|
mesodermal cell fate commitment
|
GO:0001710 |
2 |
0.999
|
Zebrafish |
|
|
negative regulation of trophoblast cell migration
|
GO:1901164 |
3 |
0.999
|
|
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.999
|
Zebrafish |
|
|
heart formation
|
GO:0060914 |
2 |
0.998
|
Human |
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.998
|
Zebrafish |
|
|
mesodermal cell fate specification
|
GO:0007501 |
2 |
0.997
|
|
|
|
atrial septum primum morphogenesis
|
GO:0003289 |
1 |
0.996
|
|
|
|
pathway restricted smad protein phosphorylation
|
GO:0060389 |
38 |
0.996
|
|
|
|
endocardial cushion development
|
GO:0003197 |
3 |
0.992
|
Mouse |
|
|
cardiac muscle cell fate commitment
|
GO:0060923 |
4 |
0.988
|
|
|
|
negative regulation of chorionic trophoblast cell proliferation
|
GO:1901383 |
2 |
0.987
|
|
|
|
endocardial cell differentiation
|
GO:0060956 |
2 |
0.985
|
|
|
|
endoderm formation
|
GO:0001706 |
33 |
0.982
|
Zebrafish |
|
|
chorionic trophoblast cell proliferation
|
GO:0097360 |
2 |
0.982
|
|
|
|
negative regulation of chondrocyte proliferation
|
GO:1902731 |
1 |
0.979
|
|
|
|
regulation of smad protein import into nucleus
|
GO:0060390 |
10 |
0.979
|
Human |
|
|
endocrine system development
|
GO:0035270 |
26 |
0.977
|
Human Mouse |
|
|
positive regulation of muscle organ development
|
GO:0048636 |
7 |
0.976
|
Human Fly |
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.975
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.974
|
Human Zebrafish |
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.972
|
Zebrafish |
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.971
|
Zebrafish |
|
|
chondrocyte development
|
GO:0002063 |
1 |
0.968
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.965
|
Mouse |
|
|
embryonic digit morphogenesis
|
GO:0042733 |
6 |
0.962
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.961
|
|
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.961
|
|
|
|
regulation of bone mineralization
|
GO:0030500 |
29 |
0.961
|
|
|
|
ectoderm development
|
GO:0007398 |
3 |
0.958
|
|
|
|
atrial septum morphogenesis
|
GO:0060413 |
5 |
0.955
|
|
|
|
regulation of determination of dorsal identity
|
GO:2000015 |
2 |
0.954
|
|
|
|
regulation of gastrulation
|
GO:0010470 |
12 |
0.951
|
Zebrafish |
|
|
mitral valve morphogenesis
|
GO:0003183 |
2 |
0.950
|
|
|
|
muscle cell fate commitment
|
GO:0042693 |
4 |
0.946
|
|
|
|
neural plate regionalization
|
GO:0060897 |
1 |
0.944
|
|
|
|
regulation of chorionic trophoblast cell proliferation
|
GO:1901382 |
2 |
0.943
|
|
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.942
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.942
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.941
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.938
|
Human |
|
|
cardiac endothelial cell differentiation
|
GO:0003348 |
2 |
0.933
|
|
|
|
mitral valve development
|
GO:0003174 |
3 |
0.932
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.930
|
|
|
|
determination of dorsal identity
|
GO:0048263 |
4 |
0.925
|
|
|
|
cardiac atrium morphogenesis
|
GO:0003209 |
7 |
0.925
|
|
|
|
blood vessel endothelial cell migration
|
GO:0043534 |
42 |
0.924
|
|
|
|
mesodermal cell differentiation
|
GO:0048333 |
10 |
0.922
|
Human Zebrafish |
|
|
positive regulation of trophoblast cell migration
|
GO:1901165 |
2 |
0.921
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.918
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.917
|
|
|
|
atrioventricular valve development
|
GO:0003171 |
3 |
0.914
|
Mouse |
|
|
endocardial cushion cell differentiation
|
GO:0061443 |
1 |
0.913
|
|
|
|
regulation of mesodermal cell fate specification
|
GO:0042661 |
2 |
0.909
|
|
|
|
activin receptor signaling pathway
|
GO:0032924 |
24 |
0.904
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.903
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.901
|
Human Zebrafish Fly |
|
|
negative regulation of epithelial cell migration
|
GO:0010633 |
38 |
0.898
|
|
|
|
endoderm development
|
GO:0007492 |
33 |
0.897
|
Zebrafish |
|
|
response to growth factor
|
GO:0070848 |
205 |
0.895
|
|
|
|
positive regulation of biomineral tissue development
|
GO:0070169 |
20 |
0.890
|
|
|
|
epithelial cell fate commitment
|
GO:0072148 |
3 |
0.889
|
|
|
|
determination of dorsal ventral asymmetry
|
GO:0048262 |
4 |
0.888
|
Zebrafish |
|
|
stem cell development
|
GO:0048864 |
69 |
0.884
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.878
|
|
|
|
positive regulation of pathway restricted smad protein phosphorylation
|
GO:0010862 |
22 |
0.877
|
|
|
|
positive regulation of endothelial cell proliferation
|
GO:0001938 |
37 |
0.866
|
|
|
|
regulation of mesoderm development
|
GO:2000380 |
4 |
0.863
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.862
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.862
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.861
|
Human Mouse |
|
|
cardiac atrium development
|
GO:0003230 |
10 |
0.859
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.855
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.844
|
Human Zebrafish Fly |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.840
|
|
|
|
regulation of blood vessel endothelial cell migration
|
GO:0043535 |
30 |
0.832
|
|
|
|
stem cell division
|
GO:0017145 |
2 |
0.829
|
Fly |
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.829
|
Human Mouse |
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.828
|
Human |
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.826
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.825
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.820
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.812
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.810
|
Human Mouse |
|
|
response to cholesterol
|
GO:0070723 |
11 |
0.809
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.809
|
|
|
|
negative regulation of endothelial cell migration
|
GO:0010596 |
29 |
0.805
|
|
|
|
positive regulation of erythrocyte differentiation
|
GO:0045648 |
11 |
0.803
|
|
|
|
lateral mesoderm development
|
GO:0048368 |
1 |
0.800
|
|
|
|
positive regulation of determination of dorsal identity
|
GO:2000017 |
1 |
0.796
|
|
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.794
|
|
|
|
negative regulation of systemic arterial blood pressure
|
GO:0003085 |
1 |
0.794
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.788
|
|
|
|
endocardial cushion cell fate commitment
|
GO:0061445 |
1 |
0.788
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.786
|
|
|
|
regulation of biomineral tissue development
|
GO:0070167 |
31 |
0.785
|
|
|
|
regulation of lung blood pressure
|
GO:0014916 |
1 |
0.778
|
|
|
|
septum primum development
|
GO:0003284 |
1 |
0.777
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.777
|
Human Zebrafish Fly |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.776
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.775
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.775
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.773
|
Human Zebrafish |
|
|
smad protein import into nucleus
|
GO:0007184 |
13 |
0.766
|
Human |
|
|
heart valve development
|
GO:0003170 |
8 |
0.763
|
Mouse |
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.755
|
|
|
|
negative regulation of locomotion
|
GO:0040013 |
118 |
0.754
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.753
|
Human Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.748
|
|
|
|
embryonic heart tube morphogenesis
|
GO:0003143 |
8 |
0.748
|
|
|
|
regulation of branching involved in ureteric bud morphogenesis
|
GO:0090189 |
3 |
0.747
|
Human |
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.746
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.744
|
|
|
|
positive regulation of smad protein import into nucleus
|
GO:0060391 |
8 |
0.733
|
Human |
|
|
positive regulation of ossification
|
GO:0045778 |
32 |
0.732
|
|
|
|
negative regulation of blood vessel endothelial cell migration
|
GO:0043537 |
16 |
0.731
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.723
|
|
|
|
negative regulation of cell adhesion
|
GO:0007162 |
64 |
0.721
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.720
|
|
|
|
endothelial cell fate commitment
|
GO:0060839 |
3 |
0.719
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.717
|
Human |
|
|
cellular response to bmp stimulus
|
GO:0071773 |
8 |
0.717
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.697
|
Human Fly |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.693
|
|
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.691
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.690
|
|
|
|
endocardial cell fate commitment
|
GO:0060957 |
1 |
0.690
|
|
|
|
palate development
|
GO:0060021 |
13 |
0.689
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.688
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.685
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.685
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.684
|
Human |
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.683
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.682
|
|
|
|
mesoderm morphogenesis
|
GO:0048332 |
11 |
0.678
|
Human Zebrafish |
|
|
response to bmp
|
GO:0071772 |
8 |
0.678
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.677
|
Zebrafish |
|
|
negative regulation of glomerulus development
|
GO:0090194 |
2 |
0.676
|
Human |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.673
|
Human Mouse |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.658
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.654
|
Human |
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.654
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.651
|
|
|
|
negative regulation of cell migration
|
GO:0030336 |
102 |
0.647
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.645
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.644
|
Human Rat |
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.643
|
Human Zebrafish Fly |
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.641
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.622
|
Human Fly |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.620
|
Human Mouse |
|
|
atrial septum development
|
GO:0003283 |
8 |
0.619
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.617
|
Human |
|
|
immune system development
|
GO:0002520 |
195 |
0.616
|
Human Fly |
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.610
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.608
|
Human Zebrafish Mouse Fly |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.604
|
Human Mouse |
|
|
negative regulation of blood pressure
|
GO:0045776 |
3 |
0.604
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.602
|
Human Mouse |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.596
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.595
|
Mouse |
|
|
wound healing
|
GO:0042060 |
115 |
0.593
|
|
|
|
regulation of glomerulus development
|
GO:0090192 |
3 |
0.589
|
Human |
|
|
mesoderm formation
|
GO:0001707 |
10 |
0.588
|
Human Zebrafish |
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.584
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.582
|
|
|
|
somite development
|
GO:0061053 |
7 |
0.580
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.578
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.577
|
Human Mouse |
|
|
regulation of endothelial cell proliferation
|
GO:0001936 |
56 |
0.576
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway
|
GO:2001237 |
52 |
0.572
|
|
|
|
regulation of erythrocyte differentiation
|
GO:0045646 |
17 |
0.568
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.567
|
Zebrafish |
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.567
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.565
|
Zebrafish Mouse |
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.560
|
Human |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.559
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.555
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.548
|
|
|
|
activation of mapkk activity
|
GO:0000186 |
18 |
0.543
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.538
|
Human Zebrafish Mouse Fly |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.532
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.532
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.526
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.525
|
Human Mouse Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.524
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.523
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.520
|
|
|
|
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090100 |
41 |
0.513
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.512
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.511
|
Human |
|
|
appendage morphogenesis
|
GO:0035107 |
16 |
0.510
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.506
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.504
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.503
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.502
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.497
|
Human Fly |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.488
|
Human |
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.488
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.479
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.478
|
Human Zebrafish Fly |
|
|
odontogenesis
|
GO:0042476 |
25 |
0.476
|
Human Mouse |
|
|
forebrain development
|
GO:0030900 |
26 |
0.476
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.472
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.468
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.466
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.465
|
|
|
|
negative regulation of kidney development
|
GO:0090185 |
2 |
0.465
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.463
|
|
|
|
regulation of systemic arterial blood pressure
|
GO:0003073 |
19 |
0.461
|
|
|
|
negative regulation of cell proliferation involved in kidney development
|
GO:1901723 |
2 |
0.460
|
Human |
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.459
|
Human |
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.458
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.452
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.452
|
Zebrafish Mouse Fly |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.452
|
|
|
|
regulation of mesenchymal cell proliferation
|
GO:0010464 |
5 |
0.451
|
Human |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.450
|
|
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.449
|
|
|
|
negative regulation of adherens junction organization
|
GO:1903392 |
5 |
0.446
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.446
|
Human |
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.446
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.437
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.435
|
Human |
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.432
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.429
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.421
|
|
|
|
regulation of cellular senescence
|
GO:2000772 |
13 |
0.421
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.420
|
|
|
|
wound healing spreading of epidermal cells
|
GO:0035313 |
6 |
0.418
|
|
|
|
cell fate specification
|
GO:0001708 |
8 |
0.417
|
Zebrafish Fly |
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.416
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.414
|
|
|
|
neural plate pattern specification
|
GO:0060896 |
1 |
0.414
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.411
|
Human |
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.411
|
Human |
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.410
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.409
|
Human |
|
|
ossification
|
GO:0001503 |
121 |
0.407
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.406
|
|
|
|
positive regulation of protein kinase b signaling
|
GO:0051897 |
42 |
0.405
|
|
|
|
striated muscle cell differentiation
|
GO:0051146 |
43 |
0.403
|
|
|
|
positive regulation of bmp signaling pathway
|
GO:0030513 |
9 |
0.403
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.401
|
Human Fly |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.399
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.399
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.398
|
Human |
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.393
|
Rat |
|
|
regulation of blood pressure
|
GO:0008217 |
30 |
0.393
|
|
|
|
epiboly involved in wound healing
|
GO:0090505 |
8 |
0.393
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.393
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.391
|
Human Fly |
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.383
|
|
|
|
focal adhesion assembly
|
GO:0048041 |
30 |
0.380
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.376
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.375
|
Human |
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.375
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.371
|
Mouse |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.371
|
Human |
|
|
dorsal ventral pattern formation
|
GO:0009953 |
15 |
0.368
|
Zebrafish Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.368
|
Mouse Rat |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.368
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.368
|
|
|
|
chondrocyte differentiation
|
GO:0002062 |
17 |
0.363
|
|
|
|
cardiac cell fate commitment
|
GO:0060911 |
7 |
0.360
|
|
|
|
negative regulation of steroid hormone biosynthetic process
|
GO:0090032 |
4 |
0.359
|
|
|
|
neuromuscular synaptic transmission
|
GO:0007274 |
5 |
0.356
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.356
|
Human |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.356
|
|
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.355
|
Zebrafish |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.353
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.351
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.349
|
Human |
|
|
left right pattern formation
|
GO:0060972 |
2 |
0.347
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.347
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.346
|
|
|
|
respiratory tube development
|
GO:0030323 |
20 |
0.344
|
Human |
|
|
respiratory system development
|
GO:0060541 |
22 |
0.342
|
Human Fly |
|
|
pattern specification involved in kidney development
|
GO:0061004 |
1 |
0.341
|
Human |
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.341
|
Zebrafish |
|
|
limb morphogenesis
|
GO:0035108 |
16 |
0.340
|
|
|
|
ureteric bud development
|
GO:0001657 |
13 |
0.338
|
Human Mouse |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.337
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.337
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.335
|
|
|
|
cardiac muscle cell differentiation
|
GO:0055007 |
15 |
0.335
|
|
|
|
biomineral tissue development
|
GO:0031214 |
39 |
0.334
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.331
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.330
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.328
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.325
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.319
|
|
|
|
heart valve morphogenesis
|
GO:0003179 |
8 |
0.318
|
Mouse |
|
|
dorsal ventral axis specification
|
GO:0009950 |
7 |
0.317
|
Zebrafish Fly |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.316
|
|
|
|
positive regulation of cardioblast differentiation
|
GO:0051891 |
2 |
0.313
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.312
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.311
|
|
|
|
apoptotic nuclear changes
|
GO:0030262 |
13 |
0.310
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.309
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.309
|
|
|
|
adherens junction organization
|
GO:0034332 |
36 |
0.308
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.305
|
|
|
|
prostate gland morphogenesis
|
GO:0060512 |
1 |
0.305
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.303
|
|
|
|
regulation of stem cell proliferation
|
GO:0072091 |
15 |
0.300
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.299
|
Human |
|
|
response to fungus
|
GO:0009620 |
4 |
0.297
|
|
|
|
regulation of mesonephros development
|
GO:0061217 |
3 |
0.296
|
Human |
|
|
positive regulation of stem cell proliferation
|
GO:2000648 |
10 |
0.295
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.295
|
|
|
|
system process
|
GO:0003008 |
349 |
0.293
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.293
|
Human |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.292
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.292
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.291
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.291
|
|
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.290
|
|
|
|
lung development
|
GO:0030324 |
20 |
0.289
|
Human |
|
|
renal system development
|
GO:0072001 |
63 |
0.288
|
Human Mouse Fly |
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.287
|
|
|
|
endocardium development
|
GO:0003157 |
2 |
0.283
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.283
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.280
|
|
|
|
male sex differentiation
|
GO:0046661 |
25 |
0.280
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.279
|
Human |
|
|
negative regulation of activin receptor signaling pathway
|
GO:0032926 |
6 |
0.278
|
|
|
|
maintenance of protein location in nucleus
|
GO:0051457 |
12 |
0.278
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.277
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.276
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.275
|
Human Mouse |
|
|
growth
|
GO:0040007 |
202 |
0.275
|
Human Fly |
|
|
response to sterol
|
GO:0036314 |
14 |
0.275
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.275
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.272
|
Human |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.271
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.271
|
Human Zebrafish Fly |
|
|
appendage development
|
GO:0048736 |
23 |
0.271
|
Fly |
|
|
embryonic appendage morphogenesis
|
GO:0035113 |
9 |
0.270
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.269
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.268
|
Human Mouse Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.264
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.263
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.263
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.263
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.260
|
Human |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.260
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.259
|
Zebrafish |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.258
|
Human |
|
|
cell junction organization
|
GO:0034330 |
79 |
0.258
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.258
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.257
|
Human |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.257
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.255
|
|
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.255
|
Human |
|
|
mesonephric tubule formation
|
GO:0072172 |
1 |
0.254
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.253
|
|
|
|
female pregnancy
|
GO:0007565 |
17 |
0.252
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.249
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.248
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.247
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.247
|
Human Fly |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.246
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.246
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.246
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.245
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.241
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.241
|
Human |
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.239
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.238
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.237
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.235
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.234
|
Fly |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.234
|
Human |
|
|
cellular response to starvation
|
GO:0009267 |
58 |
0.234
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.231
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.230
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.230
|
|
|
|
cellular component disassembly involved in execution phase of apoptosis
|
GO:0006921 |
13 |
0.230
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.228
|
Human |
|
|
regulation of protein kinase b signaling
|
GO:0051896 |
61 |
0.226
|
|
|
|
embryonic limb morphogenesis
|
GO:0030326 |
9 |
0.225
|
|
|
|
renal system pattern specification
|
GO:0072048 |
1 |
0.224
|
Human |
|
|
cartilage condensation
|
GO:0001502 |
1 |
0.222
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.221
|
|
|
|
negative regulation of dna biosynthetic process
|
GO:2000279 |
11 |
0.220
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.219
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.217
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.216
|
Human |
|
|
embryonic skeletal joint development
|
GO:0072498 |
2 |
0.216
|
|
|
|
heart looping
|
GO:0001947 |
7 |
0.216
|
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.216
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.214
|
|
|
|
mesenchymal cell proliferation
|
GO:0010463 |
7 |
0.214
|
Human Mouse |
|
|
mesenchymal to epithelial transition involved in metanephros morphogenesis
|
GO:0003337 |
4 |
0.214
|
Human |
|
|
response to alcohol
|
GO:0097305 |
64 |
0.211
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.210
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.210
|
|
|
|
head development
|
GO:0060322 |
108 |
0.210
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.208
|
Mouse Rat |
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.207
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.205
|
|
|
|
negative regulation of gastrulation
|
GO:2000542 |
4 |
0.205
|
Zebrafish |
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.204
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.203
|
Human Zebrafish Mouse Fly |
|
|
positive regulation of odontogenesis
|
GO:0042482 |
3 |
0.201
|
Mouse |
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.201
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.201
|
Human Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.201
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.200
|
|
|
|
positive regulation of cell growth
|
GO:0030307 |
48 |
0.199
|
|
|
|
endothelium development
|
GO:0003158 |
33 |
0.198
|
Human |
|
|
maintenance of location
|
GO:0051235 |
112 |
0.198
|
|
|
|
regulation of endodermal cell fate specification
|
GO:0042663 |
1 |
0.198
|
Zebrafish |
|
|
regulation of cardiac muscle tissue development
|
GO:0055024 |
13 |
0.197
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.197
|
Zebrafish Mouse Rat |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.196
|
Human |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.196
|
Human |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.195
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.193
|
|
|
|
protein kinase b signaling
|
GO:0043491 |
69 |
0.191
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.189
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.189
|
|
|
|
embryonic skeletal joint morphogenesis
|
GO:0060272 |
2 |
0.189
|
|
|
|
specification of symmetry
|
GO:0009799 |
16 |
0.188
|
Human Zebrafish |
|
|
regulation of cell substrate junction assembly
|
GO:0090109 |
20 |
0.188
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.187
|
|
|
|
ureteric bud morphogenesis
|
GO:0060675 |
10 |
0.186
|
Human Mouse |
|
|
adherens junction assembly
|
GO:0034333 |
34 |
0.184
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.184
|
Human Fly |
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.184
|
Human Zebrafish Mouse Fly |
|
|
negative regulation of cell junction assembly
|
GO:1901889 |
5 |
0.184
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.181
|
Human |
|
|
bmp signaling pathway involved in heart development
|
GO:0061312 |
3 |
0.181
|
|
|
|
catagen
|
GO:0042637 |
3 |
0.179
|
|
|
|
morphogenesis of an endothelium
|
GO:0003159 |
6 |
0.178
|
Human |
|
|
limb development
|
GO:0060173 |
23 |
0.178
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.178
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.177
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.177
|
|
|
|
lung alveolus development
|
GO:0048286 |
4 |
0.177
|
Human |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.176
|
Human |
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.176
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.175
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.175
|
Human Zebrafish Mouse Fly |
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.174
|
|
|
|
regulation of muscle tissue development
|
GO:1901861 |
26 |
0.171
|
|
|
|
morphogenesis of an epithelial sheet
|
GO:0002011 |
12 |
0.171
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.170
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.170
|
|
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.166
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.166
|
|
|
|
negative regulation of cell matrix adhesion
|
GO:0001953 |
14 |
0.166
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.166
|
Human Mouse |
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.164
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.163
|
Human Mouse |
|
|
response to drug
|
GO:0042493 |
81 |
0.163
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.163
|
Human |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.162
|
Human |
|
|
hair cycle
|
GO:0042633 |
28 |
0.162
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.162
|
|
|
|
lung morphogenesis
|
GO:0060425 |
6 |
0.161
|
Human |
|
|
cardiac epithelial to mesenchymal transition
|
GO:0060317 |
3 |
0.161
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.160
|
Human Mouse |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.160
|
Human |
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.160
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.159
|
|
|
|
positive regulation of hair cycle
|
GO:0042635 |
3 |
0.157
|
|
|
|
mesoderm development
|
GO:0007498 |
14 |
0.157
|
Human Zebrafish Fly |
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.155
|
|
|
|
positive regulation of reproductive process
|
GO:2000243 |
9 |
0.155
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.154
|
Fly |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.153
|
|
|
|
negative regulation of endodermal cell differentiation
|
GO:1903225 |
2 |
0.150
|
Zebrafish |
|
|
kidney epithelium development
|
GO:0072073 |
25 |
0.150
|
Human Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.149
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.149
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.148
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.147
|
Mouse Rat |
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.147
|
Human |
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.146
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.145
|
Human |
|
|
embryonic heart tube development
|
GO:0035050 |
9 |
0.144
|
Mouse |
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.144
|
|
|
|
nephron tubule formation
|
GO:0072079 |
1 |
0.144
|
|
