IMP

Process View

Homo sapiens

19 genes annotated in human

regulation of systemic arterial blood pressure

The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of systemic arterial blood pressure"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of systemic arterial blood pressure" (in gray)

Name	Description	Probability	Func Analog Organism
TGFB1	transforming growth factor, beta 1	0.961
ENG	endoglin	0.605
BMP2	bone morphogenetic protein 2	0.461
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.400
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.355
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.351	Human
ADORA2A	adenosine A2a receptor	0.347
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.342
TGFB3	transforming growth factor, beta 3	0.290
NOSTRIN	nitric oxide synthase trafficker	0.269
CAV1	caveolin 1, caveolae protein, 22kDa	0.234
NRP1	neuropilin 1	0.227
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.219
AXL	AXL receptor tyrosine kinase	0.216
FKBP1A	FK506 binding protein 1A, 12kDa	0.194
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.106
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.093
FSTL1	follistatin-like 1	0.088
ACVR1	activin A receptor, type I	0.079	Human
VAC14	Vac14 homolog (S. cerevisiae)	0.077
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.074
DPYSL4	dihydropyrimidinase-like 4	0.071
PRKG1	protein kinase, cGMP-dependent, type I	0.067
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.064
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.063
SDF2L1	stromal cell-derived factor 2-like 1	0.060
GDF5	growth differentiation factor 5	0.057
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.056
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.052
PDGFC	platelet derived growth factor C	0.049
TGFBR1	transforming growth factor, beta receptor 1	0.048	Human
BBS1	Bardet-Biedl syndrome 1	0.047
THBS1	thrombospondin 1	0.047
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.043	Mouse
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.043
WNK1	WNK lysine deficient protein kinase 1	0.042	Mouse
ARRDC3	arrestin domain containing 3	0.040
ARNT	aryl hydrocarbon receptor nuclear translocator	0.040
SH3BP2	SH3-domain binding protein 2	0.039
PAX8	paired box 8	0.038
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.038
SMAD7	SMAD family member 7	0.037
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.037
TIMP3	TIMP metallopeptidase inhibitor 3	0.032
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.029
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.029
BBS2	Bardet-Biedl syndrome 2	0.029
BBS9	Bardet-Biedl syndrome 9	0.027
PRKCA	protein kinase C, alpha	0.026
PDGFA	platelet-derived growth factor alpha polypeptide	0.024
DPPA4	developmental pluripotency associated 4	0.023
HYOU1	hypoxia up-regulated 1	0.023
PRNP	prion protein	0.023
GLIS2	GLIS family zinc finger 2	0.022
PSAP	prosaposin	0.020
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.019
EXOC7	exocyst complex component 7	0.019
TGFBR3	transforming growth factor, beta receptor III	0.018	Human
TTC8	tetratricopeptide repeat domain 8	0.018
HIPK2	homeodomain interacting protein kinase 2	0.018
DUSP6	dual specificity phosphatase 6	0.017
NCOA7	nuclear receptor coactivator 7	0.017
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.017
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.017
BMP4	bone morphogenetic protein 4	0.017
CALCRL	calcitonin receptor-like	0.017
PLG	plasminogen	0.016
COL6A1	collagen, type VI, alpha 1	0.016
GRB2	growth factor receptor-bound protein 2	0.016
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.016
C1QTNF1	C1q and tumor necrosis factor related protein 1	0.015
NCOA2	nuclear receptor coactivator 2	0.015
TBC1D10A	TBC1 domain family, member 10A	0.015
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.014
PURA	purine-rich element binding protein A	0.014
RARA	retinoic acid receptor, alpha	0.014
ALDOB	aldolase B, fructose-bisphosphate	0.014
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.013
GLP1R	glucagon-like peptide 1 receptor	0.013
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.013
PGD	phosphogluconate dehydrogenase	0.013
BIRC3	baculoviral IAP repeat containing 3	0.012
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.012
FGFR1	fibroblast growth factor receptor 1	0.012
CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2	0.012
CHRNA4	cholinergic receptor, nicotinic, alpha 4	0.011
ACVRL1	activin A receptor type II-like 1	0.011	Human
GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2	0.011
EDNRB	endothelin receptor type B	0.011
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.011
HDAC4	histone deacetylase 4	0.011
FHL2	four and a half LIM domains 2	0.011
IL8	interleukin 8	0.011
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.011	Human
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.011
PPIB	peptidylprolyl isomerase B (cyclophilin B)	0.011
EZR	ezrin	0.011
NAMPT	nicotinamide phosphoribosyltransferase	0.011
SMAD1	SMAD family member 1	0.010
EDN3	endothelin 3	0.010
MTHFD1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	0.010
RET	ret proto-oncogene	0.010
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.010
CXCL3	chemokine (C-X-C motif) ligand 3	0.010