Homo sapiens

0 known processes

FBXL12

F-box and leucine-rich repeat protein 12

(Aliases: Fbl12,FLJ20188)

FBXL12 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
genetic imprinting GO:0071514 1 0.787
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.542
embryonic placenta development GO:0001892 1 0.485
negative regulation of epithelial cell proliferation GO:0050680 48 0.391
regulation of cellular response to growth factor stimulus GO:0090287 76 0.330
regulation of transferase activity GO:0051338 355 0.306
response to growth factor GO:0070848 205 0.285
urogenital system development GO:0001655 65 0.268
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.255
endocrine system development GO:0035270 26 0.255
negative regulation of phosphate metabolic process GO:0045936 267 0.238
renal system development GO:0072001 63 0.230
myeloid cell differentiation GO:0030099 117 0.217
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.202
skeletal system development GO:0001501 79 0.200
regulation of kinase activity GO:0043549 314 0.193
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.192
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.188
response to transforming growth factor beta GO:0071559 94 0.177
embryonic morphogenesis GO:0048598 85 0.176
negative regulation of transferase activity GO:0051348 124 0.172
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.158
positive regulation of transforming growth factor beta receptor signaling pathway GO:0030511 12 0.155
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.149
epithelial cell proliferation GO:0050673 128 0.146
negative regulation of phosphorus metabolic process GO:0010563 267 0.145
negative regulation of kinase activity GO:0033673 106 0.141
negative regulation of phosphorylation GO:0042326 174 0.140
hemopoiesis GO:0030097 180 0.134
kidney development GO:0001822 53 0.130
negative regulation of catalytic activity GO:0043086 335 0.130
cellular response to growth factor stimulus GO:0071363 197 0.128
hematopoietic or lymphoid organ development GO:0048534 186 0.123
immune system development GO:0002520 195 0.118
enzyme linked receptor protein signaling pathway GO:0007167 303 0.105
cellular response to endogenous stimulus GO:0071495 336 0.102
post embryonic development GO:0009791 2 0.077
growth GO:0040007 202 0.066
amine metabolic process GO:0009308 44 0.061
embryonic organ development GO:0048568 36 0.061
cellular amino acid metabolic process GO:0006520 116 0.060
adrenal gland development GO:0030325 7 0.057
cellular ketone metabolic process GO:0042180 80 0.055
regulation of cell cycle GO:0051726 393 0.050
regulation of cellular amine metabolic process GO:0033238 11 0.050
regulation of cellular amino acid metabolic process GO:0006521 6 0.049
multicellular organismal aging GO:0010259 3 0.048
chordate embryonic development GO:0043009 34 0.046
placenta development GO:0001890 10 0.044
positive regulation of cellular amine metabolic process GO:0033240 7 0.042
determination of adult lifespan GO:0008340 2 0.042
nervous system development GO:0007399 293 0.037
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.036
negative regulation of protein metabolic process GO:0051248 391 0.036
mitotic cell cycle GO:0000278 326 0.036
negative regulation of apoptotic process GO:0043066 316 0.035
negative regulation of cellular protein metabolic process GO:0032269 353 0.034
cell development GO:0048468 328 0.034
uterus development GO:0060065 2 0.033
female gamete generation GO:0007292 2 0.033
generation of neurons GO:0048699 152 0.032
segmentation GO:0035282 4 0.032
positive regulation of protein phosphorylation GO:0001934 313 0.031
negative regulation of programmed cell death GO:0043069 321 0.030
protein ubiquitination GO:0016567 314 0.030
Human
positive regulation of catabolic process GO:0009896 310 0.029
cellular protein catabolic process GO:0044257 261 0.029
Human Mouse
reproductive structure development GO:0048608 55 0.029
neuron differentiation GO:0030182 138 0.028
response to abiotic stimulus GO:0009628 336 0.028
cytoplasmic transport GO:0016482 379 0.028
oogenesis GO:0048477 2 0.028
developmental maturation GO:0021700 28 0.028
chromatin modification GO:0016568 298 0.028
regulation of cell cycle process GO:0010564 266 0.028
single organism cellular localization GO:1902580 332 0.028
eye development GO:0001654 42 0.027
aging GO:0007568 66 0.027
modification dependent macromolecule catabolic process GO:0043632 212 0.026
Human Mouse
protein modification by small protein conjugation GO:0032446 342 0.026
Human
neurogenesis GO:0022008 169 0.026
negative regulation of cellular component organization GO:0051129 235 0.026
mitotic cell cycle process GO:1903047 286 0.026
neuromuscular junction development GO:0007528 3 0.026
regulation of locomotion GO:0040012 329 0.025
embryo development GO:0009790 123 0.025
reproductive process GO:0022414 106 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
modification dependent protein catabolic process GO:0019941 209 0.024
Human Mouse
negative regulation of multicellular organismal process GO:0051241 317 0.024
chromatin organization GO:0006325 351 0.024
cellular response to dna damage stimulus GO:0006974 379 0.023
covalent chromatin modification GO:0016569 254 0.023
histone modification GO:0016570 251 0.023
gland development GO:0048732 48 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.022
purine ribonucleotide catabolic process GO:0009154 404 0.022
camera type eye development GO:0043010 25 0.022
ubiquitin dependent protein catabolic process GO:0006511 206 0.022
Human Mouse
regulation of cellular ketone metabolic process GO:0010565 50 0.022
protein localization to organelle GO:0033365 280 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
blastoderm segmentation GO:0007350 2 0.022
actin filament based process GO:0030029 224 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.022
oxidation reduction process GO:0055114 396 0.022
cellular amine metabolic process GO:0044106 41 0.022
cellular macromolecular complex assembly GO:0034622 324 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
Human Mouse
organophosphate catabolic process GO:0046434 430 0.021
positive regulation of immune system process GO:0002684 283 0.021
locomotory behavior GO:0007626 1 0.021
regulation of response to external stimulus GO:0032101 222 0.021
ribonucleotide catabolic process GO:0009261 405 0.021
regulation of mapk cascade GO:0043408 262 0.021
epithelium development GO:0060429 227 0.021
morphogenesis of embryonic epithelium GO:0016331 4 0.021
carbohydrate metabolic process GO:0005975 207 0.020
nucleotide catabolic process GO:0009166 408 0.020
positive regulation of transferase activity GO:0051347 227 0.020
regulation of cell migration GO:0030334 289 0.020
negative regulation of cellular amine metabolic process GO:0033239 3 0.020
immune response GO:0006955 307 0.020
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.020
Human Mouse
purine nucleoside triphosphate metabolic process GO:0009144 412 0.020
chemical homeostasis GO:0048878 306 0.020
purine containing compound catabolic process GO:0072523 411 0.020
anterior posterior axis specification GO:0009948 2 0.020
single organism reproductive process GO:0044702 98 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
defense response GO:0006952 315 0.020
positive regulation of transport GO:0051050 336 0.020
circadian behavior GO:0048512 2 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
regulation of protein maturation GO:1903317 150 0.020
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
Human
purine ribonucleoside catabolic process GO:0046130 398 0.019
memory GO:0007613 3 0.019
positive regulation of cell death GO:0010942 263 0.019
mitotic cell cycle phase transition GO:0044772 162 0.019
positive regulation of hydrolase activity GO:0051345 331 0.019
glycosyl compound catabolic process GO:1901658 413 0.019
nitrogen compound transport GO:0071705 191 0.019
regulation of proteolysis GO:0030162 293 0.019
regulation of protein localization GO:0032880 296 0.019
ribonucleoside catabolic process GO:0042454 406 0.019
membrane organization GO:0061024 292 0.019
response to cytokine GO:0034097 232 0.018
cellular response to oxygen containing compound GO:1901701 276 0.018
developmental process involved in reproduction GO:0003006 66 0.018
oocyte development GO:0048599 1 0.018
single organism membrane organization GO:0044802 268 0.018
negative regulation of cell cycle GO:0045786 193 0.018
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.018
Human
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
cell morphogenesis GO:0000902 296 0.018
negative regulation of hydrolase activity GO:0051346 182 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
adult locomotory behavior GO:0008344 1 0.018
metal ion transport GO:0030001 272 0.017
embryonic epithelial tube formation GO:0001838 4 0.017
compound eye development GO:0048749 1 0.017
dephosphorylation GO:0016311 209 0.017
small molecule biosynthetic process GO:0044283 157 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
cellular lipid metabolic process GO:0044255 303 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
associative learning GO:0008306 1 0.017
cellular response to cytokine stimulus GO:0071345 181 0.017
response to oxygen containing compound GO:1901700 369 0.017
negative regulation of intracellular signal transduction GO:1902532 183 0.017
oocyte differentiation GO:0009994 2 0.017
regulation of apoptotic signaling pathway GO:2001233 175 0.017
transmembrane transport GO:0055085 399 0.017
rna processing GO:0006396 255 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
system process GO:0003008 349 0.017
positive regulation of cell proliferation GO:0008284 301 0.017
tripartite regional subdivision GO:0007351 2 0.017
regulation of protein processing GO:0070613 150 0.017
nucleoside phosphate catabolic process GO:1901292 412 0.016
protein maturation GO:0051604 233 0.016
regulation of endopeptidase activity GO:0052548 170 0.016
regulation of cytokine production GO:0001817 232 0.016
regulation of nucleotide metabolic process GO:0006140 269 0.016
spermatid differentiation GO:0048515 4 0.016
response to organic cyclic compound GO:0014070 204 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
regulation of growth GO:0040008 165 0.016
positive regulation of protein transport GO:0051222 135 0.016
nuclear transport GO:0051169 179 0.016
reproductive system development GO:0061458 56 0.016
rhythmic behavior GO:0007622 2 0.016
guanosine containing compound catabolic process GO:1901069 239 0.016
regulation of cell growth GO:0001558 135 0.016
regulation of cytoskeleton organization GO:0051493 177 0.016
inorganic ion transmembrane transport GO:0098660 231 0.016
purine nucleoside catabolic process GO:0006152 398 0.016
positive regulation of kinase activity GO:0033674 204 0.016
maintenance of location GO:0051235 112 0.016
cell fate determination GO:0001709 3 0.016
secretion by cell GO:0032940 226 0.016
single organism carbohydrate metabolic process GO:0044723 193 0.015
protein processing GO:0016485 226 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
rho protein signal transduction GO:0007266 26 0.015
regeneration GO:0031099 4 0.015
cardiovascular system development GO:0072358 262 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
protein targeting GO:0006605 187 0.015
regulation of peptidase activity GO:0052547 180 0.015
negative regulation of transport GO:0051051 176 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.015
protein catabolic process GO:0030163 325 0.015
Human Mouse
blood vessel morphogenesis GO:0048514 162 0.015
regulation of transcription during mitosis GO:0045896 2 0.015
neuroblast proliferation GO:0007405 4 0.015
spermatid development GO:0007286 4 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
neuron maturation GO:0042551 5 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
wnt signaling pathway GO:0016055 156 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
microtubule cytoskeleton organization GO:0000226 176 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
regulation of secretion GO:0051046 194 0.014
somatic stem cell maintenance GO:0035019 4 0.014
reactive oxygen species metabolic process GO:0072593 75 0.014
peptidyl tyrosine phosphorylation GO:0018108 170 0.014
nucleocytoplasmic transport GO:0006913 176 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
motor neuron axon guidance GO:0008045 2 0.014
regulation of intracellular protein transport GO:0033157 123 0.014
regulation of protein catabolic process GO:0042176 155 0.014
regulation of multi organism process GO:0043900 157 0.014
regulation of meiotic cell cycle GO:0051445 4 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
response to external biotic stimulus GO:0043207 261 0.014
intracellular protein transport GO:0006886 270 0.014
neural tube patterning GO:0021532 2 0.014
cell type specific apoptotic process GO:0097285 125 0.014
dna repair GO:0006281 198 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
positive regulation of cell migration GO:0030335 172 0.014
response to other organism GO:0051707 261 0.013
ras protein signal transduction GO:0007265 73 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
ion transmembrane transport GO:0034220 338 0.013
visual behavior GO:0007632 2 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
negative regulation of cell cycle process GO:0010948 121 0.013
leukocyte activation GO:0045321 164 0.013
limbic system development GO:0021761 3 0.013
blood vessel development GO:0001568 172 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
actin filament based movement GO:0030048 17 0.013
cation homeostasis GO:0055080 189 0.013
purine nucleotide catabolic process GO:0006195 405 0.013
regulation of cell division GO:0051302 116 0.013
ion homeostasis GO:0050801 230 0.013
neural tube closure GO:0001843 3 0.013
response to radiation GO:0009314 151 0.013
cellular cation homeostasis GO:0030003 163 0.013
leukocyte differentiation GO:0002521 98 0.013
neurotransmitter secretion GO:0007269 4 0.013
innate immune response GO:0045087 178 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
endosomal transport GO:0016197 129 0.013
meiosis i GO:0007127 4 0.013
peptidyl tyrosine modification GO:0018212 170 0.013
lung alveolus development GO:0048286 4 0.013
regulation of dna metabolic process GO:0051052 153 0.013
cellular response to nitrogen compound GO:1901699 144 0.012
peptidyl lysine modification GO:0018205 144 0.012
rna interference GO:0016246 4 0.012
embryonic camera type eye development GO:0031076 2 0.012
response to fungus GO:0009620 4 0.012
positive regulation of cell cycle GO:0045787 140 0.012
regulation of immune response GO:0050776 201 0.012
negative regulation of catabolic process GO:0009895 104 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
somitogenesis GO:0001756 2 0.012
blastocyst development GO:0001824 3 0.012
organelle assembly GO:0070925 176 0.012
mrna metabolic process GO:0016071 175 0.012
photoreceptor cell differentiation GO:0046530 2 0.012
negative regulation of immune system process GO:0002683 136 0.012
regulation of cellular response to stress GO:0080135 244 0.012
anterior posterior axis specification embryo GO:0008595 2 0.012
response to nitrogen compound GO:1901698 184 0.012
circulatory system development GO:0072359 262 0.012
regulation of transcription from rna polymerase ii promoter mitotic GO:0046021 1 0.012
ribonucleoside monophosphate metabolic process GO:0009161 187 0.012
response to lipid GO:0033993 206 0.012
gtp catabolic process GO:0006184 237 0.012
establishment of protein localization to organelle GO:0072594 172 0.012
cerebellum development GO:0021549 2 0.012
nucleoside catabolic process GO:0009164 408 0.012
inner ear morphogenesis GO:0042472 4 0.012
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.012
alcohol metabolic process GO:0006066 114 0.012
sleep GO:0030431 2 0.012
response to axon injury GO:0048678 1 0.012
regulation of mitotic cell cycle phase transition GO:1901990 118 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
protein autophosphorylation GO:0046777 123 0.012
tube closure GO:0060606 3 0.012
positive regulation of immune response GO:0050778 159 0.012
regulation of actin filament based process GO:0032970 141 0.012
tube development GO:0035295 125 0.012
gtp metabolic process GO:0046039 239 0.012
protein acylation GO:0043543 138 0.012
viral life cycle GO:0019058 132 0.012
cell substrate adhesion GO:0031589 132 0.012
positive regulation of secretion by cell GO:1903532 108 0.012
regulation of dephosphorylation GO:0035303 96 0.012
cellular response to lipid GO:0071396 127 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
negative regulation of protein phosphorylation GO:0001933 140 0.012
atp metabolic process GO:0046034 176 0.012
angiogenesis GO:0001525 147 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
regulation of secretion by cell GO:1903530 177 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.011
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
canonical wnt signaling pathway GO:0060070 116 0.011
translation GO:0006412 132 0.011
t cell differentiation in thymus GO:0033077 4 0.011
endomembrane system organization GO:0010256 196 0.011
cellular response to organic cyclic compound GO:0071407 127 0.011
actin mediated cell contraction GO:0070252 12 0.011
organ formation GO:0048645 3 0.011
negative regulation of gliogenesis GO:0014014 3 0.011
nucleoside monophosphate metabolic process GO:0009123 191 0.011
rna splicing GO:0008380 131 0.011
negative regulation of growth GO:0045926 97 0.011
neuron remodeling GO:0016322 2 0.011
positive regulation of neural precursor cell proliferation GO:2000179 2 0.011
vasculature development GO:0001944 181 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
regulation of cell adhesion GO:0030155 166 0.011
long term memory GO:0007616 2 0.011
cellular chemical homeostasis GO:0055082 180 0.011
regulation of protein complex assembly GO:0043254 147 0.011
carboxylic acid biosynthetic process GO:0046394 97 0.011
peripheral nervous system development GO:0007422 2 0.011
morphogenesis of a polarized epithelium GO:0001738 3 0.011
glycoprotein biosynthetic process GO:0009101 91 0.011
regulation of cell development GO:0060284 161 0.011
response to organonitrogen compound GO:0010243 156 0.011
protein import GO:0017038 130 0.011
actin cytoskeleton organization GO:0030036 207 0.011
cell maturation GO:0048469 11 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
negative regulation of cellular catabolic process GO:0031330 83 0.011
meiotic chromosome segregation GO:0045132 4 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
stem cell division GO:0017145 2 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.011
small molecule catabolic process GO:0044282 92 0.011
regulation of cysteine type endopeptidase activity GO:2000116 127 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
anion transport GO:0006820 161 0.011
positive regulation of transcription during mitosis GO:0045897 2 0.011
protein localization to nucleus GO:0034504 136 0.011
negative regulation of organelle organization GO:0010639 126 0.011
dna replication GO:0006260 116 0.011
cell part morphogenesis GO:0032990 137 0.011
negative regulation of protein maturation GO:1903318 142 0.011
glycoprotein metabolic process GO:0009100 110 0.011
organic acid biosynthetic process GO:0016053 97 0.011
calcium ion transport GO:0006816 147 0.011
regulation of wnt signaling pathway GO:0030111 123 0.010
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
positive regulation of transcription from rna polymerase ii promoter during mitosis GO:0046022 1 0.010
regulation of binding GO:0051098 111 0.010
positive regulation of cytokine production GO:0001819 167 0.010
apoptotic signaling pathway GO:0097190 268 0.010
monocarboxylic acid metabolic process GO:0032787 185 0.010
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.010
cell projection assembly GO:0030031 126 0.010
striated muscle contraction GO:0006941 52 0.010
mitotic nuclear division GO:0007067 119 0.010
immune effector process GO:0002252 159 0.010
glycerolipid metabolic process GO:0046486 107 0.010
tissue regeneration GO:0042246 3 0.010
peptidyl lysine acetylation GO:0018394 101 0.010
visual learning GO:0008542 1 0.010
negative regulation of protein modification process GO:0031400 200 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
vesicle mediated transport GO:0016192 371 0.010
positive regulation of gtpase activity GO:0043547 166 0.010
regulation of circadian sleep wake cycle GO:0042749 2 0.010
cation transmembrane transport GO:0098655 238 0.010
melanin metabolic process GO:0006582 1 0.010
regulation of canonical wnt signaling pathway GO:0060828 88 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
epidermis morphogenesis GO:0048730 3 0.010
cell cycle g2 m phase transition GO:0044839 43 0.010
forelimb morphogenesis GO:0035136 4 0.010
negative regulation of protein kinase activity GO:0006469 98 0.010
establishment or maintenance of apical basal cell polarity GO:0035088 2 0.010
sequestering of calcium ion GO:0051208 17 0.010
neurological system process GO:0050877 163 0.010
central nervous system development GO:0007417 123 0.010
circadian sleep wake cycle GO:0042745 2 0.010
sequestering of metal ion GO:0051238 24 0.010
nucleoside phosphate biosynthetic process GO:1901293 109 0.010
interspecies interaction between organisms GO:0044419 156 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010

FBXL12 disease predictions

Disease DO term ID Size Probability Func Analog Org
syndrome DOID:225 17 0.539
disease of metabolism DOID:0014667 295 0.029
musculoskeletal system disease DOID:17 223 0.023
central nervous system disease DOID:331 186 0.022
nervous system disease DOID:863 431 0.022
sensory system disease DOID:0050155 203 0.021
disease of cellular proliferation DOID:14566 174 0.019
cancer DOID:162 167 0.017
muscular disease DOID:0080000 114 0.017
muscle tissue disease DOID:66 113 0.017
organ system cancer DOID:0050686 164 0.016
cardiovascular system disease DOID:1287 106 0.015
eye and adnexa disease DOID:1492 150 0.015
eye disease DOID:5614 149 0.015
inherited metabolic disorder DOID:655 242 0.014
immune system disease DOID:2914 155 0.014
neurodegenerative disease DOID:1289 102 0.013
connective tissue disease DOID:65 109 0.013
heart disease DOID:114 68 0.013
bone disease DOID:0080001 88 0.012
retinal disease DOID:5679 118 0.012