|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.840
|
Human Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.826
|
Fly |
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.822
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.766
|
|
|
|
phagosome lysosome fusion
|
GO:0090385 |
4 |
0.665
|
|
|
|
protein auto adp ribosylation
|
GO:0070213 |
4 |
0.639
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.616
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.608
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.606
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.588
|
Fly |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.586
|
Human |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.569
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.568
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.557
|
Human |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.537
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.506
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.500
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.496
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.478
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.473
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.471
|
Human Fly |
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.469
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.459
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.446
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.444
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.423
|
Human Fly |
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.416
|
|
|
|
protein polymerization
|
GO:0051258 |
71 |
0.407
|
Fly |
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.396
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.393
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.391
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.380
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.346
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.341
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.333
|
Fly |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.329
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.323
|
Human |
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.318
|
Human Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.312
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.304
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.296
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.292
|
Human Fly |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.283
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.282
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.276
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.274
|
|
|
|
microtubule polymerization
|
GO:0046785 |
18 |
0.272
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.270
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.269
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.269
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.266
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.264
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.262
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.236
|
Human Fly |
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.235
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.231
|
|
|
|
plasma membrane raft assembly
|
GO:0044854 |
4 |
0.228
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.227
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.218
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.210
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.204
|
Fly |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.203
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.203
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.195
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.194
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.194
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.194
|
Fly |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.189
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.188
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.185
|
Fly |
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.183
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.183
|
Human |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.182
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.181
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.181
|
|
|
|
release of cytoplasmic sequestered nf kappab
|
GO:0008588 |
4 |
0.179
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.177
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.176
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.175
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.168
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.168
|
Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.167
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.165
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.165
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.164
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.162
|
Human Fly |
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.161
|
Fly |
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.161
|
Human |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.160
|
Fly |
|
|
caveola assembly
|
GO:0070836 |
4 |
0.156
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.156
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.155
|
Fly |
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.150
|
Fly |
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.148
|
Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.143
|
Human Fly |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.142
|
Fly |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.142
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.139
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.138
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.136
|
Human |
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.135
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.132
|
Fly |
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.131
|
|
|
|
phagolysosome assembly
|
GO:0001845 |
5 |
0.131
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.130
|
Fly |
|
|
cilium assembly
|
GO:0042384 |
63 |
0.130
|
Human |
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.128
|
Fly |
|
|
positive regulation of protein polymerization
|
GO:0032273 |
45 |
0.127
|
Fly |
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.126
|
Human |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.124
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.124
|
Rat Fly |
|
|
dna replication
|
GO:0006260 |
116 |
0.123
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.122
|
Fly |
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.121
|
Fly |
|
|
lysosome organization
|
GO:0007040 |
24 |
0.119
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.114
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
13 |
0.112
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.111
|
|
|
|
phagosome maturation
|
GO:0090382 |
9 |
0.111
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.107
|
Fly |
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.107
|
|
|
|
synaptic vesicle recycling
|
GO:0036465 |
3 |
0.105
|
|
|
|
telomere maintenance via telomere lengthening
|
GO:0010833 |
9 |
0.104
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.103
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.102
|
Human Fly |
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.102
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.102
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.100
|
Fly |
|
|
regulation of telomere maintenance
|
GO:0032204 |
13 |
0.100
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.100
|
|
|
|
positive regulation of actin filament polymerization
|
GO:0030838 |
38 |
0.099
|
Fly |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.098
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.097
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.097
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.096
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.096
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.096
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.095
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.094
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.093
|
|
|
|
protein poly adp ribosylation
|
GO:0070212 |
3 |
0.093
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.092
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.090
|
Fly |
|
|
cell adhesion
|
GO:0007155 |
325 |
0.090
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.089
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.088
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.088
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.087
|
|
|
|
vacuole organization
|
GO:0007033 |
44 |
0.087
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.086
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.086
|
Fly |
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.086
|
Human |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.086
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.084
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.084
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.081
|
|
|
|
lytic vacuole organization
|
GO:0080171 |
24 |
0.081
|
|
|
|
execution phase of apoptosis
|
GO:0097194 |
32 |
0.081
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.079
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.076
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.074
|
|
|
|
caveolin mediated endocytosis
|
GO:0072584 |
4 |
0.074
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.073
|
Fly |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.073
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.073
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.073
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.072
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.072
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.072
|
Human |
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.072
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.071
|
|
|
|
regulation of microtubule polymerization
|
GO:0031113 |
12 |
0.071
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.071
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.071
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.070
|
Fly |
|
|
cell fate determination
|
GO:0001709 |
3 |
0.070
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.068
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.068
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.067
|
Fly |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.066
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.064
|
|
|
|
positive regulation of homotypic cell cell adhesion
|
GO:0034112 |
4 |
0.064
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.063
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.063
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.063
|
|
|
|
tnfsf11 mediated signaling pathway
|
GO:0071847 |
2 |
0.062
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.061
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.061
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.061
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.061
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.060
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.060
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.060
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.059
|
|
|
|
positive regulation of telomere maintenance
|
GO:0032206 |
4 |
0.059
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.059
|
|
|
|
telomere maintenance via telomerase
|
GO:0007004 |
8 |
0.059
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.058
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.057
|
Human |
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.057
|
|
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.057
|
Fly |
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.057
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.056
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.056
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.056
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.055
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.054
|
|
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.054
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.053
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.053
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.053
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.052
|
Human |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.051
|
|
|
|
membrane raft organization
|
GO:0031579 |
10 |
0.051
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.051
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.050
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.050
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.049
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.049
|
|
|
|
single organism membrane fusion
|
GO:0044801 |
37 |
0.049
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.048
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.048
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.048
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.048
|
Fly |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.047
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.047
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.047
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.047
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.046
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.045
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.045
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.045
|
|
|
|
negative regulation of synaptic transmission
|
GO:0050805 |
2 |
0.045
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.044
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.044
|
|
|
|
melanin metabolic process
|
GO:0006582 |
1 |
0.044
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.042
|
|
|
|
membrane biogenesis
|
GO:0044091 |
13 |
0.042
|
|
|
|
protein localization to chromosome telomeric region
|
GO:0070198 |
6 |
0.042
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.042
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.041
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.041
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.041
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.041
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.041
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.041
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.040
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.040
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.040
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.040
|
Human |
|
|
convergent extension
|
GO:0060026 |
1 |
0.040
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.039
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.039
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.039
|
|
|
|
plasma membrane raft organization
|
GO:0044857 |
4 |
0.039
|
|
|
|
regulation of telomere maintenance via telomerase
|
GO:0032210 |
6 |
0.039
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.038
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.038
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.038
|
|
|
|
positive regulation of leukocyte differentiation
|
GO:1902107 |
37 |
0.037
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.037
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.036
|
Human Fly |
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.035
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.035
|
|
|
|
growth
|
GO:0040007 |
202 |
0.035
|
Fly |
|
|
membrane fusion
|
GO:0061025 |
43 |
0.034
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.034
|
Fly |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.034
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.034
|
|
|
|
phagocytosis
|
GO:0006909 |
42 |
0.034
|
|
|
|
cell junction maintenance
|
GO:0034331 |
4 |
0.034
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.034
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.034
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.033
|
Human |
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.033
|
|
|
|
membrane raft assembly
|
GO:0001765 |
7 |
0.033
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.033
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.032
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.032
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.032
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.032
|
Human |
|
|
negative regulation of dna binding
|
GO:0043392 |
18 |
0.032
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.032
|
|
|
|
vesicle organization
|
GO:0016050 |
62 |
0.032
|
Human |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.031
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.031
|
|
|
|
vesicle localization
|
GO:0051648 |
26 |
0.031
|
Human |
|
|
adult locomotory behavior
|
GO:0008344 |
1 |
0.031
|
|
|
|
protein adp ribosylation
|
GO:0006471 |
9 |
0.031
|
|
|
|
memory
|
GO:0007613 |
3 |
0.031
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.030
|
|
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.030
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.030
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.030
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.030
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.030
|
|
|
|
organelle fusion
|
GO:0048284 |
36 |
0.030
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.029
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.029
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.029
|
|
|
|
apoptotic cell clearance
|
GO:0043277 |
12 |
0.029
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.029
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.029
|
|
|
|
membrane assembly
|
GO:0071709 |
10 |
0.029
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.028
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.028
|
Human Fly |
|
|
epithelium development
|
GO:0060429 |
227 |
0.028
|
Fly |
|
|
cilium organization
|
GO:0044782 |
68 |
0.028
|
Human |
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.027
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.027
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.027
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.027
|
|
|
|
synaptic vesicle transport
|
GO:0048489 |
5 |
0.027
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.027
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.027
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.027
|
|
|
|
protein lipid complex subunit organization
|
GO:0071825 |
24 |
0.027
|
|
|
|
long term memory
|
GO:0007616 |
2 |
0.027
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.026
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.026
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.026
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.026
|
Fly |
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.026
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.025
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.025
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.025
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.025
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.025
|
|
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.025
|
Human |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.025
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.025
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.025
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.025
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.024
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.024
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.024
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.024
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.024
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.024
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.024
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.024
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.024
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.024
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.024
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.023
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.023
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.023
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.023
|
|
|
|
regulation of microtubule polymerization or depolymerization
|
GO:0031110 |
27 |
0.023
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.023
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.023
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.023
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.022
|
|
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.022
|
Fly |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.022
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.022
|
|
|
|
tissue homeostasis
|
GO:0001894 |
63 |
0.022
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.022
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.022
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.022
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.022
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.022
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.021
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.021
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.021
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.021
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.021
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.021
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.021
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.021
|
|
|
|
synapse assembly
|
GO:0007416 |
8 |
0.021
|
Fly |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.021
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.021
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.021
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.021
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.021
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.021
|
|
|
|
actin nucleation
|
GO:0045010 |
21 |
0.020
|
Fly |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.020
|
|
|
|
vesicle fusion
|
GO:0006906 |
17 |
0.020
|
|
|
|
positive regulation of myeloid cell differentiation
|
GO:0045639 |
39 |
0.020
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.020
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.020
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.020
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.020
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.020
|
|
|
|
positive regulation of erk1 and erk2 cascade via tnfsf11 mediated signaling
|
GO:0071848 |
2 |
0.020
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.020
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.020
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.020
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.019
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.019
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.019
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.019
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.019
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.019
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.019
|
|
|
|
regulation of neuron migration
|
GO:2001222 |
3 |
0.019
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.019
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.019
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.019
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.019
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.019
|
|
|
|
positive regulation of sarcomere organization
|
GO:0060298 |
2 |
0.019
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.019
|
Fly |
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.019
|
|
|
|
regulation of dephosphorylation
|
GO:0035303 |
96 |
0.019
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.019
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.018
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.018
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.018
|
|
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.018
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.018
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.018
|
Human |
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.018
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.018
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.018
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.018
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.018
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.018
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.018
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.017
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.017
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.017
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.017
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.017
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.017
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.017
|
Fly |
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.017
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.017
|
|
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.017
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.017
|
Fly |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.017
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.017
|
Human |
|
|
mast cell degranulation
|
GO:0043303 |
4 |
0.017
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.017
|
|
|
|
regulation of membrane protein ectodomain proteolysis
|
GO:0051043 |
17 |
0.017
|
|
|
|
mast cell activation involved in immune response
|
GO:0002279 |
4 |
0.017
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.017
|
|
|
|
monocyte chemotaxis
|
GO:0002548 |
20 |
0.016
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.016
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.016
|
|
|
|
synaptic vesicle localization
|
GO:0097479 |
5 |
0.016
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.016
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.016
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.016
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.016
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.016
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.016
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.016
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.016
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.016
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.016
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.016
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.016
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.016
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.015
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.015
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.015
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.015
|
|
|
|
rna dependent dna replication
|
GO:0006278 |
16 |
0.015
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.015
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.015
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.015
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.015
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.015
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.015
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.015
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.015
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.015
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.015
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.015
|
|
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.015
|
|
|
|
mating
|
GO:0007618 |
1 |
0.015
|
|
|
|
positive regulation of cell cell adhesion
|
GO:0022409 |
22 |
0.015
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.015
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.015
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.015
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.015
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.014
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.014
|
|
