IMP

Process View

Homo sapiens

2 genes annotated in human

positive regulation of sarcomere organization

Any process that increases the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of sarcomere organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of sarcomere organization" (in gray)

Name	Description	Probability
FNBP1L	formin binding protein 1-like	0.862
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.549
BMPR1B	bone morphogenetic protein receptor, type IB	0.534
HNF4A	hepatocyte nuclear factor 4, alpha	0.403
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.153
NOG	noggin	0.082
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.080
TRIP10	thyroid hormone receptor interactor 10	0.044
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.029
FNBP1	formin binding protein 1	0.019
BMP4	bone morphogenetic protein 4	0.019
CTBP2	C-terminal binding protein 2	0.018
BMP2	bone morphogenetic protein 2	0.017
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.017
COL2A1	collagen, type II, alpha 1	0.016
ACAN	aggrecan	0.015
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.015
BMPR1A	bone morphogenetic protein receptor, type IA	0.014
SOX1	SRY (sex determining region Y)-box 1	0.011
HNF1A	HNF1 homeobox A	0.010
SREBF2	sterol regulatory element binding transcription factor 2	0.010
HAND1	heart and neural crest derivatives expressed 1	0.010
PITX2	paired-like homeodomain 2	0.010