|
|
chromatin organization
|
GO:0006325 |
351 |
0.984
|
Fly |
|
|
negative regulation of bmp signaling pathway
|
GO:0030514 |
17 |
0.979
|
|
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.976
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.964
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.952
|
|
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.926
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.909
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.825
|
Fly |
|
|
neuron fate commitment
|
GO:0048663 |
2 |
0.792
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.708
|
Zebrafish |
|
|
oogenesis
|
GO:0048477 |
2 |
0.689
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.686
|
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
27 |
0.677
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.662
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.658
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.654
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.577
|
|
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.545
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.543
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.540
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.532
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.504
|
Human |
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.482
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.475
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.461
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.456
|
Human |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.452
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.419
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.375
|
Fly |
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.350
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.336
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.330
|
Fly |
|
|
cell development
|
GO:0048468 |
328 |
0.322
|
Fly |
|
|
viral process
|
GO:0016032 |
146 |
0.320
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.279
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.278
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.271
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.265
|
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
80 |
0.264
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.259
|
Fly |
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.255
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.244
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.244
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.243
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.239
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.226
|
Human |
|
|
dna templated transcription initiation
|
GO:0006352 |
35 |
0.220
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.217
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.216
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.214
|
Fly |
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.204
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.199
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.194
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.193
|
Human |
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.192
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.188
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.186
|
Human |
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.183
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.179
|
Human |
|
|
positive regulation of nervous system development
|
GO:0051962 |
54 |
0.175
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.171
|
Fly |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.171
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.169
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.163
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.159
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.158
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.157
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.155
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.155
|
Human |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.154
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.153
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.151
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.146
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.146
|
|
|
|
nucleosome organization
|
GO:0034728 |
66 |
0.145
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.145
|
Zebrafish |
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.144
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.142
|
Human |
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.141
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.140
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.139
|
Human |
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.136
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.134
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.134
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.133
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.133
|
Human |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.133
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.132
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.131
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.130
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.130
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.129
|
Human |
|
|
embryonic camera type eye morphogenesis
|
GO:0048596 |
2 |
0.129
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.128
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.128
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.127
|
Human |
|
|
symbiosis encompassing mutualism through parasitism
|
GO:0044403 |
156 |
0.125
|
Human |
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.125
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.124
|
|
|
|
rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0051123 |
4 |
0.121
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.121
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.120
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.117
|
|
|
|
embryonic cranial skeleton morphogenesis
|
GO:0048701 |
6 |
0.117
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.115
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.115
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.114
|
|
|
|
growth
|
GO:0040007 |
202 |
0.114
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.113
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.112
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.112
|
Human |
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.111
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.110
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.108
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.107
|
Human |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.106
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.106
|
Zebrafish |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.102
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.102
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.101
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.099
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.098
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.098
|
Human |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.098
|
Human |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.098
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.096
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.096
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.096
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.096
|
Human |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.095
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.094
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.090
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.090
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.089
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.089
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.089
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.087
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.087
|
Human |
|
|
histone acetylation
|
GO:0016573 |
93 |
0.087
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.087
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.087
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.087
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.086
|
|
|
|
embryonic eye morphogenesis
|
GO:0048048 |
2 |
0.085
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.084
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.084
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.084
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.083
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.082
|
Human |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.082
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.082
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.081
|
Human |
|
|
response to other organism
|
GO:0051707 |
261 |
0.081
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.081
|
|
|
|
histone lysine methylation
|
GO:0034968 |
50 |
0.079
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.079
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.079
|
Human |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.079
|
Human |
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.078
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.078
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.077
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.076
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.076
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.076
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.076
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.076
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.075
|
Human |
|
|
tube development
|
GO:0035295 |
125 |
0.075
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.073
|
Zebrafish |
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.073
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.072
|
|
|
|
cell proliferation involved in heart valve development
|
GO:2000793 |
1 |
0.072
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.072
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.071
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.071
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.070
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.070
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.069
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.069
|
Human |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.068
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.068
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.068
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.066
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.066
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.066
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.065
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.065
|
Fly |
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.065
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.065
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.065
|
|
|
|
lens morphogenesis in camera type eye
|
GO:0002089 |
2 |
0.064
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.063
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.063
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.062
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.061
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.061
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.061
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.058
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.058
|
Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.057
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.057
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.056
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.056
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.056
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.055
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.054
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.054
|
|
|
|
dna templated transcription elongation
|
GO:0006354 |
25 |
0.054
|
Zebrafish |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.053
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.053
|
Human |
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.053
|
Human |
|
|
heart valve formation
|
GO:0003188 |
2 |
0.053
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.053
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.052
|
Human |
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.052
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.051
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.051
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.050
|
Human |
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.050
|
|
|
|
smad protein complex assembly
|
GO:0007183 |
12 |
0.050
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.049
|
|
|
|
positive regulation of cell projection organization
|
GO:0031346 |
64 |
0.048
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.048
|
|
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.048
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.048
|
Fly |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.047
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.047
|
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.047
|
Zebrafish |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.047
|
|
|
|
positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left right asymmetry
|
GO:1900224 |
1 |
0.047
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.046
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.046
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.046
|
Human |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.045
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.045
|
|
|
|
regulation of organelle assembly
|
GO:1902115 |
40 |
0.045
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.043
|
|
|
|
immunoglobulin v d j recombination
|
GO:0033152 |
1 |
0.043
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.042
|
|
|
|
gonad development
|
GO:0008406 |
34 |
0.042
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.042
|
Fly |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.041
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.041
|
Human |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.041
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.041
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.041
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.040
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.040
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.040
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.040
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.040
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.040
|
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.040
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.039
|
|
|
|
positive regulation of leukocyte proliferation
|
GO:0070665 |
48 |
0.039
|
|
|
|
embryonic camera type eye development
|
GO:0031076 |
2 |
0.039
|
|
|
|
v d j recombination
|
GO:0033151 |
3 |
0.039
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.038
|
Zebrafish |
|
|
cardiac left ventricle formation
|
GO:0003218 |
1 |
0.038
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.038
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.037
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.036
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.036
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.036
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.036
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.036
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.036
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.035
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.035
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.034
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.034
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.034
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.034
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.034
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.034
|
Fly |
|
|
methylation
|
GO:0032259 |
106 |
0.033
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.033
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.033
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.033
|
Fly |
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.033
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.033
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.033
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.032
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.032
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.032
|
Human |
|
|
blood vessel development
|
GO:0001568 |
172 |
0.032
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.032
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.032
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.032
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.032
|
|
|
|
embryonic skeletal system development
|
GO:0048706 |
13 |
0.032
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.031
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.031
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.031
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.031
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.031
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.030
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.030
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.030
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.030
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.030
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.030
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.030
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.029
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.029
|
|
|
|
regulation of bmp signaling pathway
|
GO:0030510 |
27 |
0.029
|
|
|
|
viral transcription
|
GO:0019083 |
35 |
0.029
|
|
|
|
basophil differentiation
|
GO:0030221 |
2 |
0.029
|
|
|
|
negative regulation of immune response
|
GO:0050777 |
40 |
0.029
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.028
|
Human |
|
|
cell differentiation in spinal cord
|
GO:0021515 |
1 |
0.028
|
|
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.028
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.028
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.028
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.028
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.028
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.028
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.028
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.028
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.028
|
Human |
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.028
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.027
|
Human |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.027
|
|
|
|
blood vessel maturation
|
GO:0001955 |
1 |
0.027
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.026
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.026
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.026
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.026
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.026
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.026
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.026
|
|
|
|
system process
|
GO:0003008 |
349 |
0.026
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.026
|
Human |
|
|
development of primary sexual characteristics
|
GO:0045137 |
35 |
0.025
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.025
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.025
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.025
|
|
|
|
pericardium development
|
GO:0060039 |
2 |
0.025
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.025
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.025
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.025
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.025
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.025
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.024
|
Human |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.024
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.024
|
Fly |
|
|
positive regulation of viral process
|
GO:0048524 |
37 |
0.024
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.024
|
|
|
|
positive regulation of transcription factor import into nucleus
|
GO:0042993 |
25 |
0.024
|
Human |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.024
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.024
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.024
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.023
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.023
|
|
|
|
regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060260 |
8 |
0.023
|
|
|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.023
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.023
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.023
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.023
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.022
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.022
|
Human |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.022
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.022
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.022
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.022
|
|
|
|
regulation of viral transcription
|
GO:0046782 |
34 |
0.022
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.022
|
Human |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.022
|
Human |
|
|
negative regulation of transforming growth factor beta receptor signaling pathway
|
GO:0030512 |
28 |
0.022
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.022
|
Human |
|
|
kidney development
|
GO:0001822 |
53 |
0.022
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.022
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.022
|
|
|
|
protein sumoylation
|
GO:0016925 |
25 |
0.022
|
Human |
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.022
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.022
|
|
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.021
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.021
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.021
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.021
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.021
|
Human |
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.021
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.021
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.021
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.020
|
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.020
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.020
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.020
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.020
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.020
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.020
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.019
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.019
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.019
|
|
|
|
positive regulation of leukocyte activation
|
GO:0002696 |
80 |
0.019
|
|
|
|
regulation of schwann cell proliferation
|
GO:0010624 |
1 |
0.019
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.019
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.019
|
Human |
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.019
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.019
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.019
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.019
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.019
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.019
|
|
|
|
multi organism metabolic process
|
GO:0044033 |
41 |
0.019
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.019
|
|
|
|
regulation of chromatin assembly or disassembly
|
GO:0001672 |
6 |
0.018
|
|
|
|
regulation of gene silencing
|
GO:0060968 |
24 |
0.018
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.018
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.018
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.018
|
|
|
|
cardiac right ventricle formation
|
GO:0003219 |
1 |
0.018
|
|
|
|
b cell activation
|
GO:0042113 |
33 |
0.018
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.018
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.017
|
|
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.017
|
|
|
|
somatic diversification of immunoglobulins
|
GO:0016445 |
6 |
0.017
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.017
|
|
|
|
positive regulation of monocyte chemotactic protein 1 production
|
GO:0071639 |
3 |
0.017
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.017
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.017
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.017
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.017
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.017
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.017
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.017
|
Fly |
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.017
|
|
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.017
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.017
|
|
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.016
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.016
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.016
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.016
|
|
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.016
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.016
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.016
|
Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.016
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.016
|
|
|
|
negative regulation of neurogenesis
|
GO:0050768 |
26 |
0.016
|
|
|
|
regulation of multicellular organism growth
|
GO:0040014 |
8 |
0.016
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.016
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.016
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.016
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.016
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.016
|
|
|
|
mitotic sister chromatid separation
|
GO:0051306 |
18 |
0.015
|
|
|
|
behavioral response to ethanol
|
GO:0048149 |
2 |
0.015
|
|
|
|
eye morphogenesis
|
GO:0048592 |
16 |
0.015
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.015
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.015
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.015
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.015
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.015
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.015
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.015
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.015
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.015
|
|
|
|
regulation of dna templated transcription initiation
|
GO:2000142 |
9 |
0.015
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.015
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.015
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.015
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.015
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.015
|
|
|
|
camera type eye development
|
GO:0043010 |
25 |
0.015
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.015
|
|
|
|
columnar cuboidal epithelial cell differentiation
|
GO:0002065 |
14 |
0.015
|
|
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.015
|
|
|
|
b cell proliferation
|
GO:0042100 |
22 |
0.015
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.015
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.015
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.014
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.014
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.014
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.014
|
|
|
|
body morphogenesis
|
GO:0010171 |
11 |
0.014
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.014
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.014
|
Human |
|
|
cardiac conduction
|
GO:0061337 |
23 |
0.014
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.014
|
|
|
|
positive regulation of viral transcription
|
GO:0050434 |
13 |
0.014
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.014
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.014
|
|
|
|
spindle elongation
|
GO:0051231 |
4 |
0.013
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.013
|
|
|
|
positive regulation of dna repair
|
GO:0045739 |
25 |
0.013
|
Human |
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.013
|
|
