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Homo sapiens

22 genes annotated in human

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b cell proliferation

GO:0042100

The expansion of a B cell population by cell division. Follows B cell activation.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "b cell proliferation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "b cell proliferation" (in gray)

Name	Description	Probability	Func Analog Organism
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.862
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.834
IL4R	interleukin 4 receptor	0.666
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.423
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.404
SYK	spleen tyrosine kinase	0.361
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.356
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.332
IL10RA	interleukin 10 receptor, alpha	0.234
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.222	Mouse
CD80	CD80 molecule	0.221
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.179
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.154
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.131
TAL1	T-cell acute lymphocytic leukemia 1	0.123
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.106
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.098	Mouse
CD22	CD22 molecule	0.096
CD79B	CD79b molecule, immunoglobulin-associated beta	0.095
BCL2	B-cell CLL/lymphoma 2	0.094
TICAM2	toll-like receptor adaptor molecule 2	0.092
LAT	linker for activation of T cells	0.089
BCL2L1	BCL2-like 1	0.082	Human
IL2RG	interleukin 2 receptor, gamma	0.080
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.080	Human
MYD88	myeloid differentiation primary response gene (88)	0.080
SLAMF1	signaling lymphocytic activation molecule family member 1	0.077
APAF1	apoptotic peptidase activating factor 1	0.069
BLNK	B-cell linker	0.069
SH3BP2	SH3-domain binding protein 2	0.066
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.063
IL22RA2	interleukin 22 receptor, alpha 2	0.062
EP300	E1A binding protein p300	0.054
XIAP	X-linked inhibitor of apoptosis	0.054
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.051
CCR7	chemokine (C-C motif) receptor 7	0.049
CD86	CD86 molecule	0.047
GRAP2	GRB2-related adaptor protein 2	0.046
CDK6	cyclin-dependent kinase 6	0.045
CDK2	cyclin-dependent kinase 2	0.044
BIRC3	baculoviral IAP repeat containing 3	0.043
TFF1	trefoil factor 1	0.043
PECAM1	platelet/endothelial cell adhesion molecule	0.042
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.041
CCND1	cyclin D1	0.040
VAV1	vav 1 guanine nucleotide exchange factor	0.039	Human
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.038
INSR	insulin receptor	0.038
LCK	lymphocyte-specific protein tyrosine kinase	0.037
CXCR4	chemokine (C-X-C motif) receptor 4	0.037
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.034
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.034	Mouse
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.033
GRB7	growth factor receptor-bound protein 7	0.033
CD19	CD19 molecule	0.031
MUC1	mucin 1, cell surface associated	0.031
TCF4	transcription factor 4	0.030	Human
HDAC9	histone deacetylase 9	0.030
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.029	Mouse
GAS7	growth arrest-specific 7	0.028
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.027
CDCP1	CUB domain containing protein 1	0.027
TP53	tumor protein p53	0.027
SH2D1A	SH2 domain containing 1A	0.027
ARNT	aryl hydrocarbon receptor nuclear translocator	0.026
PRKCB	protein kinase C, beta	0.025
RB1	retinoblastoma 1	0.025
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.025
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.024
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.024
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.024
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.024
PIAS4	protein inhibitor of activated STAT, 4	0.023
ABI2	abl-interactor 2	0.023
MSH5	mutS homolog 5 (E. coli)	0.022
CCND3	cyclin D3	0.022
CYSLTR1	cysteinyl leukotriene receptor 1	0.022	Human
LY96	lymphocyte antigen 96	0.022
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.021
IRF4	interferon regulatory factor 4	0.021
IL22RA1	interleukin 22 receptor, alpha 1	0.020
BAK1	BCL2-antagonist/killer 1	0.020
WASF1	WAS protein family, member 1	0.019
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.019
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	0.019
GRB10	growth factor receptor-bound protein 10	0.018
PILRA	paired immunoglobin-like type 2 receptor alpha	0.018
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.018
NCOA7	nuclear receptor coactivator 7	0.018
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.018
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.018
HDAC4	histone deacetylase 4	0.018
RNF144B	ring finger protein 144B	0.017
GAB2	GRB2-associated binding protein 2	0.017
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.017
DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17	0.017
IRS1	insulin receptor substrate 1	0.017
MAPK12	mitogen-activated protein kinase 12	0.017
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.016
FERMT2	fermitin family member 2	0.016
CSK	c-src tyrosine kinase	0.016
SIGLEC7	sialic acid binding Ig-like lectin 7	0.016
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.015
FOXP3	forkhead box P3	0.015
EGR1	early growth response 1	0.015
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.015
CD33	CD33 molecule	0.015
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.015
TRAF3	TNF receptor-associated factor 3	0.015
IRAK4	interleukin-1 receptor-associated kinase 4	0.015
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.015
TRAT1	T cell receptor associated transmembrane adaptor 1	0.015
CD72	CD72 molecule	0.015
TRIM33	tripartite motif containing 33	0.015
BID	BH3 interacting domain death agonist	0.015
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.015
KLF6	Kruppel-like factor 6	0.015
IL2RA	interleukin 2 receptor, alpha	0.014
CYSLTR2	cysteinyl leukotriene receptor 2	0.014	Human
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.014
FAIM3	Fas apoptotic inhibitory molecule 3	0.014
SMC1A	structural maintenance of chromosomes 1A	0.014
HDAC1	histone deacetylase 1	0.014
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.014
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.014
UBASH3B	ubiquitin associated and SH3 domain containing B	0.014
RHOH	ras homolog gene family, member H	0.014
TCF12	transcription factor 12	0.014	Human
HCK	hemopoietic cell kinase	0.013
ITK	IL2-inducible T-cell kinase	0.013
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.013
CD6	CD6 molecule	0.013
SLA	Src-like-adaptor	0.013
APP	amyloid beta (A4) precursor protein	0.013
CXCR5	chemokine (C-X-C motif) receptor 5	0.013
CDK4	cyclin-dependent kinase 4	0.013
RUNX1	runt-related transcription factor 1	0.013
SPRR2D	small proline-rich protein 2D	0.013
CD27	CD27 molecule	0.013
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.013
ZNF282	zinc finger protein 282	0.013
CD84	CD84 molecule	0.013
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.013
JAK1	Janus kinase 1	0.013
CD37	CD37 molecule	0.012
PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	0.012
NME1	non-metastatic cells 1, protein (NM23A) expressed in	0.012
GFER	growth factor, augmenter of liver regeneration	0.012
TRAF5	TNF receptor-associated factor 5	0.012
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.012
IGSF6	immunoglobulin superfamily, member 6	0.012
JAK3	Janus kinase 3	0.012
FYB	FYN binding protein	0.012
NCF4	neutrophil cytosolic factor 4, 40kDa	0.012
TRAF3IP3	TRAF3 interacting protein 3	0.012
TXK	TXK tyrosine kinase	0.012
FANCD2	Fanconi anemia, complementation group D2	0.012
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.012
CCNDBP1	cyclin D-type binding-protein 1	0.012
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.012	Mouse
GPR65	G protein-coupled receptor 65	0.011
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.011
HDAC5	histone deacetylase 5	0.011
BAD	BCL2-associated agonist of cell death	0.011
EVI2A	ecotropic viral integration site 2A	0.011
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.011
PPAP2B	phosphatidic acid phosphatase type 2B	0.011
TRAF1	TNF receptor-associated factor 1	0.011
BCL2A1	BCL2-related protein A1	0.011
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.011
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.011
IFNG	interferon, gamma	0.011
IKZF1	IKAROS family zinc finger 1 (Ikaros)	0.011
IRAK1	interleukin-1 receptor-associated kinase 1	0.011
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.011
IRF8	interferon regulatory factor 8	0.011
ARHGAP25	Rho GTPase activating protein 25	0.011
CNR2	cannabinoid receptor 2 (macrophage)	0.010
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.010
IL2RB	interleukin 2 receptor, beta	0.010
SH2D1B	SH2 domain containing 1B	0.010
RNR2	l-rRNA	0.010
DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	0.010
CD28	CD28 molecule	0.010	Human
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.010	Human
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.010
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.010	Human
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.010
PIM1	pim-1 oncogene	0.010
GLIS2	GLIS family zinc finger 2	0.010
CD180	CD180 molecule	0.010
CD69	CD69 molecule	0.010
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.010
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.010
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.010