Homo sapiens

0 known processes

CRELD2

cysteine-rich with EGF-like domains 2

(Aliases: DKFZp667O055,MGC11256)

CRELD2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of systemic arterial blood pressure GO:0003084 2 0.503
hindbrain development GO:0030902 3 0.220
glycoprotein biosynthetic process GO:0009101 91 0.217
regulation of blood vessel size GO:0050880 18 0.173
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.167
neurological system process GO:0050877 163 0.156
positive regulation of blood pressure GO:0045777 3 0.132
ribonucleotide catabolic process GO:0009261 405 0.122
cellular response to toxic substance GO:0097237 4 0.121
regulation of protein secretion GO:0050708 86 0.098
metencephalon development GO:0022037 2 0.093
enzyme linked receptor protein signaling pathway GO:0007167 303 0.084
glycosyl compound catabolic process GO:1901658 413 0.080
intracellular protein transport GO:0006886 270 0.074
protein maturation GO:0051604 233 0.072
gtp metabolic process GO:0046039 239 0.068
single organism cellular localization GO:1902580 332 0.068
system process GO:0003008 349 0.063
cellular response to dna damage stimulus GO:0006974 379 0.063
posttranscriptional regulation of gene expression GO:0010608 213 0.062
secretion by cell GO:0032940 226 0.060
cerebellar cortex development GO:0021695 1 0.059
cerebellum development GO:0021549 2 0.058
positive regulation of catabolic process GO:0009896 310 0.056
single organism carbohydrate metabolic process GO:0044723 193 0.055
regulation of cell cycle GO:0051726 393 0.054
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.053
multicellular organismal metabolic process GO:0044236 34 0.052
regulation of establishment of protein localization GO:0070201 242 0.052
cytoplasmic transport GO:0016482 379 0.049
glycoprotein metabolic process GO:0009100 110 0.049
positive regulation of insulin like growth factor receptor signaling pathway GO:0043568 4 0.048
neurological system process involved in regulation of systemic arterial blood pressure GO:0001976 2 0.048
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.046
positive regulation of protein kinase activity GO:0045860 190 0.046
positive regulation of nucleotide catabolic process GO:0030813 185 0.046
regulation of transferase activity GO:0051338 355 0.045
positive regulation of steroid hormone biosynthetic process GO:0090031 2 0.044
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
regulation of secretion GO:0051046 194 0.042
regulation of cell cycle process GO:0010564 266 0.042
dna replication GO:0006260 116 0.041
membrane organization GO:0061024 292 0.041
purine ribonucleotide catabolic process GO:0009154 404 0.041
regulation of kinase activity GO:0043549 314 0.040
skeletal system development GO:0001501 79 0.039
chondrocyte development GO:0002063 1 0.039
positive regulation of cellular component organization GO:0051130 376 0.039
endomembrane system organization GO:0010256 196 0.038
protein modification by small protein conjugation GO:0032446 342 0.038
positive regulation of hydrolase activity GO:0051345 331 0.037
central nervous system development GO:0007417 123 0.037
bone development GO:0060348 26 0.037
regulation of protein serine threonine kinase activity GO:0071900 179 0.036
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.036
ribonucleoside triphosphate metabolic process GO:0009199 412 0.036
positive regulation of hormone biosynthetic process GO:0046886 4 0.036
protein localization to organelle GO:0033365 280 0.036
nervous system development GO:0007399 293 0.035
purine ribonucleoside metabolic process GO:0046128 437 0.035
regulation of wnt protein secretion GO:0061356 1 0.035
protein ubiquitination GO:0016567 314 0.034
protein catabolic process GO:0030163 325 0.034
negative regulation of phosphate metabolic process GO:0045936 267 0.034
regulation of protein kinase activity GO:0045859 289 0.033
positive regulation of protein phosphorylation GO:0001934 313 0.033
regulation of cellular amino acid metabolic process GO:0006521 6 0.033
organophosphate catabolic process GO:0046434 430 0.033
carbohydrate metabolic process GO:0005975 207 0.033
purine nucleoside catabolic process GO:0006152 398 0.032
negative regulation of protein metabolic process GO:0051248 391 0.032
response to abiotic stimulus GO:0009628 336 0.032
vesicle organization GO:0016050 62 0.032
purine containing compound catabolic process GO:0072523 411 0.032
nucleocytoplasmic transport GO:0006913 176 0.032
segmentation GO:0035282 4 0.031
positive regulation of gtp catabolic process GO:0033126 166 0.031
regulation of growth GO:0040008 165 0.031
carbohydrate derivative biosynthetic process GO:1901137 207 0.031
response to cytokine GO:0034097 232 0.031
positive regulation of dna metabolic process GO:0051054 73 0.030
memory GO:0007613 3 0.030
guanosine containing compound catabolic process GO:1901069 239 0.030
nucleoside triphosphate metabolic process GO:0009141 422 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
positive regulation of cell cycle process GO:0090068 106 0.029
endochondral bone morphogenesis GO:0060350 3 0.029
cell type specific apoptotic process GO:0097285 125 0.028
mrna modification GO:0016556 6 0.027
cellular response to organonitrogen compound GO:0071417 124 0.027
regulation of intracellular transport GO:0032386 195 0.027
positive regulation of cellular catabolic process GO:0031331 284 0.027
regulation of protein transport GO:0051223 213 0.026
positive regulation of kinase activity GO:0033674 204 0.026
positive regulation of nucleoside metabolic process GO:0045979 186 0.026
maintenance of location GO:0051235 112 0.026
cranial nerve development GO:0021545 4 0.026
cellular macromolecule catabolic process GO:0044265 380 0.025
nuclear transport GO:0051169 179 0.025
i kappab kinase nf kappab signaling GO:0007249 166 0.025
regulation of intracellular protein transport GO:0033157 123 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
innate immune response GO:0045087 178 0.025
guanosine containing compound metabolic process GO:1901068 244 0.024
positive regulation of intracellular transport GO:0032388 104 0.024
mitotic cell cycle GO:0000278 326 0.024
modification dependent macromolecule catabolic process GO:0043632 212 0.024
reactive nitrogen species metabolic process GO:2001057 3 0.024
regulation of secretion by cell GO:1903530 177 0.024
regulation of mitotic cell cycle GO:0007346 189 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
response to growth factor GO:0070848 205 0.024
protein secretion GO:0009306 98 0.023
regulation of dna replication GO:0006275 68 0.023
regulation of multi organism process GO:0043900 157 0.023
regulation of protein stability GO:0031647 87 0.023
regulation of gtpase activity GO:0043087 180 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.023
cellular protein catabolic process GO:0044257 261 0.022
somitogenesis GO:0001756 2 0.022
regulation of nucleocytoplasmic transport GO:0046822 98 0.022
dopaminergic neuron differentiation GO:0071542 1 0.022
mrna metabolic process GO:0016071 175 0.022
regeneration GO:0031099 4 0.022
positive regulation of secretion GO:0051047 116 0.022
negative regulation of phosphorylation GO:0042326 174 0.022
response to external biotic stimulus GO:0043207 261 0.022
post embryonic development GO:0009791 2 0.022
protein localization to membrane GO:0072657 160 0.022
regulation of cytoplasmic transport GO:1903649 149 0.022
protein targeting to membrane GO:0006612 42 0.021
response to oxygen containing compound GO:1901700 369 0.021
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.021
protein stabilization GO:0050821 64 0.021
chondrocyte differentiation involved in endochondral bone morphogenesis GO:0003413 1 0.021
protein targeting GO:0006605 187 0.021
wnt protein secretion GO:0061355 1 0.020
connective tissue development GO:0061448 39 0.020
tissue regeneration GO:0042246 3 0.020
regulation of protein localization GO:0032880 296 0.020
signal transduction by phosphorylation GO:0023014 297 0.020
osteoblast differentiation GO:0001649 92 0.020
negative regulation of phosphorus metabolic process GO:0010563 267 0.020
cartilage development GO:0051216 31 0.020
regulation of dna metabolic process GO:0051052 153 0.020
meiosis i GO:0007127 4 0.020
protein localization to nucleus GO:0034504 136 0.019
mitotic cell cycle process GO:1903047 286 0.019
head development GO:0060322 108 0.019
regulation of cell division GO:0051302 116 0.019
response to axon injury GO:0048678 1 0.019
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
regulation of nucleotide catabolic process GO:0030811 205 0.018
positive regulation of transport GO:0051050 336 0.018
negative regulation of cell differentiation GO:0045596 171 0.018
establishment of protein localization to membrane GO:0090150 121 0.018
small gtpase mediated signal transduction GO:0007264 78 0.018
rna interference GO:0016246 4 0.018
behavior GO:0007610 112 0.018
gtp catabolic process GO:0006184 237 0.018
secretion GO:0046903 254 0.018
response to transforming growth factor beta GO:0071559 94 0.018
positive regulation of gtpase activity GO:0043547 166 0.018
transmembrane transport GO:0055085 399 0.018
modification dependent protein catabolic process GO:0019941 209 0.018
epidermis morphogenesis GO:0048730 3 0.018
regulation of response to external stimulus GO:0032101 222 0.018
regulation of protein catabolic process GO:0042176 155 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.017
inflammatory response GO:0006954 79 0.017
rna modification GO:0009451 27 0.017
protein glycosylation GO:0006486 62 0.017
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.017
organ morphogenesis GO:0009887 147 0.017
positive regulation of cell cycle GO:0045787 140 0.017
ribonucleoside triphosphate catabolic process GO:0009203 391 0.017
response to radiation GO:0009314 151 0.017
regulation of gtp catabolic process GO:0033124 180 0.016
positive regulation of nucleotide metabolic process GO:0045981 230 0.016
regulation of nuclease activity GO:0032069 11 0.016
locomotory behavior GO:0007626 1 0.016
spermatid differentiation GO:0048515 4 0.016
negative regulation of transferase activity GO:0051348 124 0.016
cellular ketone metabolic process GO:0042180 80 0.016
positive regulation of organelle organization GO:0010638 195 0.016
er nucleus signaling pathway GO:0006984 23 0.016
response to decreased oxygen levels GO:0036293 96 0.016
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.016
response to wounding GO:0009611 168 0.016
positive regulation of cell death GO:0010942 263 0.016
cellular response to nitrogen compound GO:1901699 144 0.016
cellular response to starvation GO:0009267 58 0.016
positive regulation of immune system process GO:0002684 283 0.016
non canonical wnt signaling pathway via mapk cascade GO:0038030 4 0.016
vasoconstriction GO:0042310 11 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
cellular amine metabolic process GO:0044106 41 0.015
posttranslational protein targeting to membrane GO:0006620 5 0.015
regulation of cell adhesion GO:0030155 166 0.015
centrosome organization GO:0051297 58 0.015
early endosome to golgi transport GO:0034498 3 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
microtubule cytoskeleton organization GO:0000226 176 0.015
activation of signaling protein activity involved in unfolded protein response GO:0006987 3 0.015
regulation of cellular component movement GO:0051270 334 0.015
response to nitrogen compound GO:1901698 184 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
glycosylation GO:0070085 71 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
immune response GO:0006955 307 0.015
mapk cascade GO:0000165 288 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
purine nucleotide catabolic process GO:0006195 405 0.014
oxidation reduction process GO:0055114 396 0.014
lipid localization GO:0010876 106 0.014
regulation of mapk cascade GO:0043408 262 0.014
lipid metabolic process GO:0006629 381 0.014
regulation of feeding behavior GO:0060259 3 0.014
blastoderm segmentation GO:0007350 2 0.014
centrosome cycle GO:0007098 32 0.014
negative regulation of cell cycle GO:0045786 193 0.013
chromatin modification GO:0016568 298 0.013
negative regulation of developmental process GO:0051093 247 0.013
female gamete generation GO:0007292 2 0.013
actin cytoskeleton organization GO:0030036 207 0.013
positive regulation of protein transport GO:0051222 135 0.013
positive regulation of dna replication GO:0045740 35 0.013
regulation of locomotion GO:0040012 329 0.013
cellular macromolecular complex assembly GO:0034622 324 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
cellular carbohydrate biosynthetic process GO:0034637 21 0.013
positive regulation of secretion by cell GO:1903532 108 0.013
proteoglycan metabolic process GO:0006029 29 0.013
amine metabolic process GO:0009308 44 0.013
positive regulation of synaptic transmission GO:0050806 4 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
positive regulation of calcineurin nfat signaling cascade GO:0070886 4 0.013
positive regulation of transferase activity GO:0051347 227 0.013
positive regulation of mitotic cell cycle GO:0045931 60 0.013
motor neuron axon guidance GO:0008045 2 0.013
cell development GO:0048468 328 0.013
photoreceptor cell differentiation GO:0046530 2 0.013
oocyte differentiation GO:0009994 2 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
muscle structure development GO:0061061 98 0.013
nerve development GO:0021675 4 0.013
cell adhesion GO:0007155 325 0.012
cranial nerve morphogenesis GO:0021602 1 0.012
cell division GO:0051301 168 0.012
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.012
positive regulation of intracellular protein transport GO:0090316 76 0.012
negative regulation of kinase activity GO:0033673 106 0.012
fibroblast proliferation GO:0048144 33 0.012
wound healing GO:0042060 115 0.012
regulation of cellular ketone metabolic process GO:0010565 50 0.012
nucleotide catabolic process GO:0009166 408 0.012
reproduction GO:0000003 63 0.012
regulation of cellular response to growth factor stimulus GO:0090287 76 0.012
associative learning GO:0008306 1 0.012
collagen metabolic process GO:0032963 28 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
neuromuscular junction development GO:0007528 3 0.012
growth GO:0040007 202 0.012
actin filament based process GO:0030029 224 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
neuron differentiation GO:0030182 138 0.012
oogenesis GO:0048477 2 0.012
visual learning GO:0008542 1 0.011
protein import into nucleus GO:0006606 104 0.011
regulation of t cell activation GO:0050863 77 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
regulation of blood pressure GO:0008217 30 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
protein processing GO:0016485 226 0.011
regulation of cellular response to stress GO:0080135 244 0.011
regulation of binding GO:0051098 111 0.011
organonitrogen compound biosynthetic process GO:1901566 200 0.011
positive regulation of signal transduction by p53 class mediator GO:1901798 10 0.011
nuclear export GO:0051168 69 0.011
oocyte development GO:0048599 1 0.011
visual behavior GO:0007632 2 0.011
regulation of behavior GO:0050795 82 0.011
optic nerve development GO:0021554 2 0.011
negative regulation of epidermal cell differentiation GO:0045605 4 0.011
regulation of cell differentiation GO:0045595 393 0.011
sensory perception of pain GO:0019233 4 0.011
negative regulation of response to external stimulus GO:0032102 83 0.011
positive regulation of cellular protein catabolic process GO:1903364 37 0.011
regulation of cytokinesis GO:0032465 45 0.011
skeletal system morphogenesis GO:0048705 24 0.011
negative regulation of hepatocyte growth factor receptor signaling pathway GO:1902203 1 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
immune effector process GO:0002252 159 0.011
organelle fission GO:0048285 149 0.011
nucleoside catabolic process GO:0009164 408 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
intracellular protein transmembrane import GO:0044743 23 0.011
apoptotic signaling pathway GO:0097190 268 0.011
organophosphate biosynthetic process GO:0090407 163 0.011
regulation of map kinase activity GO:0043405 108 0.011
positive regulation of wnt signaling pathway GO:0030177 54 0.011
multicellular organismal macromolecule metabolic process GO:0044259 29 0.011
defense response GO:0006952 315 0.010
determination of adult lifespan GO:0008340 2 0.010
single organism membrane organization GO:0044802 268 0.010
cytokinesis GO:0000910 96 0.010
protein heterotrimerization GO:0070208 4 0.010
positive regulation of cytokine production GO:0001819 167 0.010
regulation of purine nucleotide catabolic process GO:0033121 205 0.010
pattern specification process GO:0007389 43 0.010
macromolecule glycosylation GO:0043413 63 0.010
muscle tissue development GO:0060537 62 0.010
bone mineralization GO:0030282 34 0.010
negative regulation of immune system process GO:0002683 136 0.010
cytokine secretion GO:0050663 64 0.010
dephosphorylation GO:0016311 209 0.010
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.010
lymphocyte activation GO:0046649 133 0.010
regulation of protein processing GO:0070613 150 0.010
microtubule based process GO:0007017 210 0.010
reactive oxygen species biosynthetic process GO:1903409 4 0.010
protein targeting to nucleus GO:0044744 104 0.010

CRELD2 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.720
bone development disease DOID:0080006 55 0.338
bone disease DOID:0080001 88 0.338
connective tissue disease DOID:65 109 0.338
osteochondrodysplasia DOID:2256 35 0.261
osteogenesis imperfecta DOID:12347 13 0.152
myopathy DOID:423 104 0.077
muscular disease DOID:0080000 114 0.077
muscle tissue disease DOID:66 113 0.077
muscular dystrophy DOID:9884 51 0.024
congenital muscular dystrophy DOID:0050557 22 0.014
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014