IMP

Process View

Homo sapiens

1 genes annotated in human

chondrocyte development

GO:0002063

The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "chondrocyte development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "chondrocyte development" (in gray)

Name	Description	Probability	Func Analog Organism
TGFB1	transforming growth factor, beta 1	0.997
FKBP1A	FK506 binding protein 1A, 12kDa	0.996
BMP2	bone morphogenetic protein 2	0.968
TGFB3	transforming growth factor, beta 3	0.951
ENG	endoglin	0.946
PRKG1	protein kinase, cGMP-dependent, type I	0.867
SMAD7	SMAD family member 7	0.799
FSTL1	follistatin-like 1	0.732
NRP1	neuropilin 1	0.569
GDF5	growth differentiation factor 5	0.551
TGFBR1	transforming growth factor, beta receptor 1	0.496	Human
BMPR1A	bone morphogenetic protein receptor, type IA	0.377	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.361	Human Mouse
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.258
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.214
MAPK8	mitogen-activated protein kinase 8	0.214
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.151
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.118
ZMYND11	zinc finger, MYND-type containing 11	0.104
SMAD2	SMAD family member 2	0.099
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.085
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.082
ACVR1	activin A receptor, type I	0.076	Human
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.069
COL1A2	collagen, type I, alpha 2	0.062
THBS2	thrombospondin 2	0.061
POSTN	periostin, osteoblast specific factor	0.061
MSX1	msh homeobox 1	0.060
BMP4	bone morphogenetic protein 4	0.058
PCGF2	polycomb group ring finger 2	0.058
WISP1	WNT1 inducible signaling pathway protein 1	0.054
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.054
COL5A2	collagen, type V, alpha 2	0.052
AXIN1	axin 1	0.048
PRRX1	paired related homeobox 1	0.048
PDGFC	platelet derived growth factor C	0.044
THBS1	thrombospondin 1	0.042
MXRA5	matrix-remodelling associated 5	0.040
COL1A1	collagen, type I, alpha 1	0.040
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.039
CRELD2	cysteine-rich with EGF-like domains 2	0.039
VCAN	versican	0.035
VEGFA	vascular endothelial growth factor A	0.034
SFRP4	secreted frizzled-related protein 4	0.033
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.032
C2orf18	chromosome 2 open reading frame 18	0.031
COL5A1	collagen, type V, alpha 1	0.029
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.029
BCOR	BCL6 corepressor	0.029
COL3A1	collagen, type III, alpha 1	0.028
IQGAP1	IQ motif containing GTPase activating protein 1	0.028
COMP	cartilage oligomeric matrix protein	0.027
SORBS3	sorbin and SH3 domain containing 3	0.027
BGN	biglycan	0.027
RARA	retinoic acid receptor, alpha	0.027
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.026
NRP2	neuropilin 2	0.026
LAMB1	laminin, beta 1	0.024
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.024
SMAD1	SMAD family member 1	0.023
FNDC3B	fibronectin type III domain containing 3B	0.023
TGFBR3	transforming growth factor, beta receptor III	0.023
JAG1	jagged 1	0.023
FNDC1	fibronectin type III domain containing 1	0.023
PDGFA	platelet-derived growth factor alpha polypeptide	0.023
THY1	Thy-1 cell surface antigen	0.022
COL10A1	collagen, type X, alpha 1	0.022
TGFB2	transforming growth factor, beta 2	0.022
LRRC15	leucine rich repeat containing 15	0.021
FZD7	frizzled homolog 7 (Drosophila)	0.021
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.021
SMAD6	SMAD family member 6	0.021
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.020
TWIST1	twist homolog 1 (Drosophila)	0.020
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.020
ADAM12	ADAM metallopeptidase domain 12	0.020
ZFYVE9	zinc finger, FYVE domain containing 9	0.019
ANTXR2	anthrax toxin receptor 2	0.018
CTHRC1	collagen triple helix repeat containing 1	0.018
CD248	CD248 molecule, endosialin	0.017
BMPR1B	bone morphogenetic protein receptor, type IB	0.017	Human
DLX5	distal-less homeobox 5	0.017
LUM	lumican	0.017
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.017
RXRA	retinoid X receptor, alpha	0.017
COL6A1	collagen, type VI, alpha 1	0.017
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.016
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.016
FAP	fibroblast activation protein, alpha	0.016
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.016
CLU	clusterin	0.016
SPRED1	sprouty-related, EVH1 domain containing 1	0.016
NTM	neurotrimin	0.016
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.015
MSX2	msh homeobox 2	0.015	Mouse
TSC22D1	TSC22 domain family, member 1	0.015
SOX7	SRY (sex determining region Y)-box 7	0.014
JUN	jun proto-oncogene	0.014
RUNX2	runt-related transcription factor 2	0.014	Mouse
USP15	ubiquitin specific peptidase 15	0.014
COL11A1	collagen, type XI, alpha 1	0.014	Mouse
EDNRA	endothelin receptor type A	0.014
COL6A3	collagen, type VI, alpha 3	0.014
INHBA	inhibin, beta A	0.013
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.013
DLG5	discs, large homolog 5 (Drosophila)	0.013
ARFGAP3	ADP-ribosylation factor GTPase activating protein 3	0.013
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.013
SOX11	SRY (sex determining region Y)-box 11	0.013
COL12A1	collagen, type XII, alpha 1	0.013
ASPN	asporin	0.013
ARRDC3	arrestin domain containing 3	0.013
SPHK1	sphingosine kinase 1	0.013
NOX4	NADPH oxidase 4	0.013
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.012
LEPRE1	leucine proline-enriched proteoglycan (leprecan) 1	0.012
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.012
ZNF576	zinc finger protein 576	0.012
GSK3A	glycogen synthase kinase 3 alpha	0.012
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.012
ACVR2A	activin A receptor, type IIA	0.012
SPOCK1	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1	0.012
SMAD4	SMAD family member 4	0.012
MBNL2	muscleblind-like 2 (Drosophila)	0.012
FOXD1	forkhead box D1	0.012
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.012
TRAM2	translocation associated membrane protein 2	0.011
ZMYND8	zinc finger, MYND-type containing 8	0.011
ACVR2B	activin A receptor, type IIB	0.011
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.011
ZFP28	zinc finger protein 28 homolog (mouse)	0.011
MFAP2	microfibrillar-associated protein 2	0.011
ATP2B4	ATPase, Ca++ transporting, plasma membrane 4	0.011
MFAP5	microfibrillar associated protein 5	0.011
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.011
C22orf39	chromosome 22 open reading frame 39	0.011
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.011
CRABP2	cellular retinoic acid binding protein 2	0.011
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.011
ACY3	aspartoacylase (aminocyclase) 3	0.011
GREM1	gremlin 1	0.011
ANGPTL2	angiopoietin-like 2	0.010
LOX	lysyl oxidase	0.010
RNF2	ring finger protein 2	0.010
HEG1	HEG homolog 1 (zebrafish)	0.010
RGS4	regulator of G-protein signaling 4	0.010
NOG	noggin	0.010
ARMCX3	armadillo repeat containing, X-linked 3	0.010
IGFBP5	insulin-like growth factor binding protein 5	0.010
FHL1	four and a half LIM domains 1	0.010