Homo sapiens

7 known processes

IL2RG

interleukin 2 receptor, gamma

(Aliases: IMD4,CD132,IL-2RG,SCIDX,CIDX,SCIDX1,P64)

IL2RG biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
lymphocyte activation GO:0046649 133 0.930
Mouse
leukocyte activation GO:0045321 164 0.926
Mouse
cell activation GO:0001775 213 0.903
Mouse
negative regulation of cd4 positive alpha beta t cell activation GO:2000515 1 0.881
adaptive immune response GO:0002250 49 0.881
positive regulation of immunoglobulin production GO:0002639 4 0.868
lymphocyte proliferation GO:0046651 70 0.851
leukocyte proliferation GO:0070661 74 0.797
myeloid dendritic cell chemotaxis GO:0002408 3 0.780
cd4 positive alpha beta t cell differentiation involved in immune response GO:0002294 4 0.756
regulation of immune response GO:0050776 201 0.755
regulation of leukocyte mediated immunity GO:0002703 38 0.753
regulation of lymphocyte activation GO:0051249 103 0.740
Mouse
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 3 0.737
Mouse
hematopoietic or lymphoid organ development GO:0048534 186 0.726
Mouse
positive regulation of cell activation GO:0050867 81 0.714
Mouse
immune effector process GO:0002252 159 0.708
regulation of cell differentiation GO:0045595 393 0.696
Mouse
positive regulation of leukocyte proliferation GO:0070665 48 0.689
negative regulation of alpha beta t cell activation GO:0046636 3 0.668
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.652
Mouse
leukocyte differentiation GO:0002521 98 0.643
Mouse
immune response GO:0006955 307 0.640
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.610
immune system development GO:0002520 195 0.598
Mouse
positive regulation of cell differentiation GO:0045597 211 0.585
Mouse
regulation of immune effector process GO:0002697 91 0.585
osteoclast differentiation GO:0030316 21 0.582
negative regulation of multicellular organismal process GO:0051241 317 0.578
positive regulation of lymphocyte activation GO:0051251 73 0.575
Mouse
small gtpase mediated signal transduction GO:0007264 78 0.574
positive regulation of immune system process GO:0002684 283 0.573
Mouse
defense response GO:0006952 315 0.542
negative regulation of cell proliferation GO:0008285 228 0.541
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.540
regulation of cell activation GO:0050865 125 0.527
Mouse
regulation of t cell proliferation GO:0042129 42 0.519
leukocyte mediated immunity GO:0002443 59 0.519
mononuclear cell proliferation GO:0032943 71 0.517
regulation of leukocyte proliferation GO:0070663 67 0.507
lymphocyte mediated immunity GO:0002449 48 0.503
regulation of cytokine production GO:0001817 232 0.492
negative regulation of immune response GO:0050777 40 0.489
negative regulation of developmental process GO:0051093 247 0.488
positive regulation of t cell activation GO:0050870 54 0.488
Mouse
cellular response to cytokine stimulus GO:0071345 181 0.479
hemopoiesis GO:0030097 180 0.469
Mouse
regulation of adaptive immune response GO:0002819 33 0.459
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.459
response to biotic stimulus GO:0009607 276 0.457
positive regulation of leukocyte differentiation GO:1902107 37 0.452
Mouse
alpha beta t cell differentiation involved in immune response GO:0002293 5 0.445
t cell activation GO:0042110 99 0.445
Mouse
regulation of leukocyte differentiation GO:1902105 61 0.437
Mouse
negative regulation of immune system process GO:0002683 136 0.437
regulation of lymphocyte proliferation GO:0050670 64 0.432
positive regulation of developmental process GO:0051094 314 0.429
Mouse
regulation of response to external stimulus GO:0032101 222 0.424
response to other organism GO:0051707 261 0.422
cytokine production GO:0001816 247 0.419
regulation of lymphocyte mediated immunity GO:0002706 33 0.417
cell chemotaxis GO:0060326 112 0.417
t cell cytokine production GO:0002369 12 0.414
regulation of leukocyte chemotaxis GO:0002688 46 0.411
negative regulation of t cell cytokine production GO:0002725 4 0.402
exocytosis GO:0006887 71 0.399
response to cytokine GO:0034097 232 0.397
positive regulation of immune response GO:0050778 159 0.395
b cell activation GO:0042113 33 0.395
Mouse
t helper cell differentiation GO:0042093 4 0.387
positive regulation of cytokine production GO:0001819 167 0.378
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.371
positive regulation of b cell mediated immunity GO:0002714 4 0.361
positive regulation of leukocyte activation GO:0002696 80 0.359
Mouse
regulation of mononuclear cell proliferation GO:0032944 65 0.353
positive regulation of chemotaxis GO:0050921 57 0.350
metal ion transport GO:0030001 272 0.347
positive regulation of myoblast fusion GO:1901741 1 0.342
negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002823 8 0.332
response to external biotic stimulus GO:0043207 261 0.328
t helper 1 cell differentiation GO:0045063 1 0.327
regulation of chemotaxis GO:0050920 74 0.327
production of molecular mediator of immune response GO:0002440 37 0.326
positive regulation of phosphorylation GO:0042327 394 0.325
regulation of leukocyte activation GO:0002694 115 0.323
Mouse
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.321
positive regulation of production of molecular mediator of immune response GO:0002702 11 0.318
positive regulation of alpha beta t cell activation GO:0046635 10 0.316
Mouse
positive regulation of cellular amine metabolic process GO:0033240 7 0.315
cytokine mediated signaling pathway GO:0019221 109 0.312
cell adhesion GO:0007155 325 0.309
t cell proliferation GO:0042098 45 0.305
ras protein signal transduction GO:0007265 73 0.300
negative regulation of cell differentiation GO:0045596 171 0.296
positive regulation of gtp catabolic process GO:0033126 166 0.296
regulation of muscle cell differentiation GO:0051147 31 0.289
eosinophil activation involved in immune response GO:0002278 2 0.289
positive regulation of cell proliferation GO:0008284 301 0.285
positive regulation of cd8 positive alpha beta t cell proliferation GO:2000566 1 0.279
positive regulation of neutrophil chemotaxis GO:0090023 7 0.271
positive regulation of leukocyte chemotaxis GO:0002690 38 0.262
syncytium formation by plasma membrane fusion GO:0000768 2 0.261
regulation of t cell activation GO:0050863 77 0.261
Mouse
regulation of leukocyte migration GO:0002685 63 0.259
regulation of intracellular transport GO:0032386 195 0.254
negative regulation of adaptive immune response GO:0002820 9 0.253
actin filament based process GO:0030029 224 0.252
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.250
regulation of myoblast fusion GO:1901739 1 0.249
metal ion homeostasis GO:0055065 169 0.249
positive regulation of lymphocyte proliferation GO:0050671 46 0.249
negative regulation of apoptotic process GO:0043066 316 0.247
leukocyte migration GO:0050900 107 0.245
positive regulation of mononuclear cell proliferation GO:0032946 47 0.241
myoblast fusion GO:0007520 1 0.240
leukocyte activation involved in immune response GO:0002366 30 0.237
regulation of mast cell degranulation GO:0043304 3 0.225
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.217
positive regulation of t cell proliferation GO:0042102 33 0.217
positive regulation of t helper cell differentiation GO:0045624 2 0.214
regulation of granulocyte chemotaxis GO:0071622 16 0.214
regulation of mhc class ii biosynthetic process GO:0045346 4 0.212
negative regulation of immune effector process GO:0002698 38 0.211
positive regulation of cellular component organization GO:0051130 376 0.210
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.207
positive regulation of calcium ion transport GO:0051928 51 0.206
t helper 1 type immune response GO:0042088 8 0.204
cellular amino acid metabolic process GO:0006520 116 0.204
cellular divalent inorganic cation homeostasis GO:0072503 128 0.202
regulation of immunoglobulin production GO:0002637 4 0.202
cell activation involved in immune response GO:0002263 30 0.202
t cell differentiation in thymus GO:0033077 4 0.200
Mouse
single organism cellular localization GO:1902580 332 0.200
cellular ketone metabolic process GO:0042180 80 0.195
isotype switching GO:0045190 3 0.194
regulation of myeloid cell differentiation GO:0045637 81 0.193
cellular calcium ion homeostasis GO:0006874 117 0.192
negative regulation of leukocyte activation GO:0002695 26 0.188
regulation of cellular amino acid metabolic process GO:0006521 6 0.187
cation transport GO:0006812 331 0.186
mature natural killer cell chemotaxis GO:0035782 1 0.185
granulocyte migration GO:0097530 40 0.185
positive regulation of nucleotide catabolic process GO:0030813 185 0.181
positive regulation of hydrolase activity GO:0051345 331 0.181
tyrosine phosphorylation of stat protein GO:0007260 33 0.179
t cell mediated immunity GO:0002456 25 0.179
negative regulation of cell death GO:0060548 345 0.179
positive regulation of response to external stimulus GO:0032103 88 0.177
leukocyte chemotaxis GO:0030595 76 0.177
regulation of neutrophil migration GO:1902622 10 0.177
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.168
regulation of anatomical structure morphogenesis GO:0022603 286 0.167
regulation of cell migration GO:0030334 289 0.167
mapk cascade GO:0000165 288 0.164
negative regulation of cell activation GO:0050866 33 0.164
positive regulation of intracellular transport GO:0032388 104 0.163
t cell differentiation GO:0030217 29 0.161
Mouse
chemokine c c motif ligand 11 production GO:0071954 1 0.160
positive regulation of transport GO:0051050 336 0.160
regulation of production of molecular mediator of immune response GO:0002700 25 0.159
lipid metabolic process GO:0006629 381 0.158
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.158
positive regulation of immune effector process GO:0002699 40 0.156
positive regulation of muscle cell differentiation GO:0051149 15 0.156
alpha beta t cell activation involved in immune response GO:0002287 5 0.155
cytokine production involved in immune response GO:0002367 27 0.155
positive regulation of locomotion GO:0040017 186 0.150
lymphocyte differentiation GO:0030098 35 0.149
Mouse
regulation of jak stat cascade GO:0046425 44 0.146
chemotaxis GO:0006935 157 0.144
negative regulation of myeloid cell differentiation GO:0045638 42 0.143
regulation of lymphocyte differentiation GO:0045619 22 0.143
Mouse
regulation of alpha beta t cell differentiation GO:0046637 5 0.142
Mouse
secretion by cell GO:0032940 226 0.142
negative regulation of myeloid leukocyte differentiation GO:0002762 16 0.141
mast cell activation involved in immune response GO:0002279 4 0.140
cellular amine metabolic process GO:0044106 41 0.139
innate immune response GO:0045087 178 0.137
glial cell migration GO:0008347 4 0.137
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.135
cellular response to tumor necrosis factor GO:0071356 63 0.134
i kappab kinase nf kappab signaling GO:0007249 166 0.133
positive regulation of ras gtpase activity GO:0032320 117 0.130
rho protein signal transduction GO:0007266 26 0.130
regulation of cellular ketone metabolic process GO:0010565 50 0.129
mast cell degranulation GO:0043303 4 0.128
calcium ion homeostasis GO:0055074 122 0.128
myeloid leukocyte activation GO:0002274 34 0.127
astrocyte chemotaxis GO:0035700 1 0.127
positive regulation of protein kinase activity GO:0045860 190 0.127
positive regulation of syncytium formation by plasma membrane fusion GO:0060143 2 0.126
activated t cell proliferation GO:0050798 13 0.125
cellular ion homeostasis GO:0006873 168 0.123
calcium mediated signaling GO:0019722 44 0.123
alpha beta t cell activation GO:0046631 15 0.121
Mouse
regulation of purine nucleotide metabolic process GO:1900542 264 0.121
regulation of t helper cell differentiation GO:0045622 3 0.121
positive regulation of myeloid leukocyte mediated immunity GO:0002888 1 0.120
t helper 2 cell differentiation GO:0045064 1 0.120
ribonucleotide catabolic process GO:0009261 405 0.120
post embryonic development GO:0009791 2 0.120
positive regulation of cell motility GO:2000147 177 0.119
g protein coupled receptor signaling pathway GO:0007186 207 0.119
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.118
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.117
memory GO:0007613 3 0.117
negative regulation of programmed cell death GO:0043069 321 0.117
vesicle mediated transport GO:0016192 371 0.117
cellular metal ion homeostasis GO:0006875 146 0.116
regulation of cellular component movement GO:0051270 334 0.115
positive regulation of neutrophil migration GO:1902624 7 0.114
amine metabolic process GO:0009308 44 0.114
glycosyl compound catabolic process GO:1901658 413 0.114
regulation of secretion by cell GO:1903530 177 0.112
positive regulation of leukocyte degranulation GO:0043302 3 0.111
regulation of leukocyte apoptotic process GO:2000106 25 0.110
cellular response to oxygen containing compound GO:1901701 276 0.110
regulation of t cell differentiation GO:0045580 19 0.109
Mouse
regulation of multi organism process GO:0043900 157 0.109
regulation of nucleotide metabolic process GO:0006140 269 0.109
t cell differentiation involved in immune response GO:0002292 7 0.108
myeloid leukocyte migration GO:0097529 62 0.107
positive regulation of granulocyte chemotaxis GO:0071624 9 0.106
nucleotide catabolic process GO:0009166 408 0.106
purine nucleoside catabolic process GO:0006152 398 0.105
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.105
actin cytoskeleton organization GO:0030036 207 0.104
alpha beta t cell differentiation GO:0046632 7 0.103
Mouse
myeloid cell activation involved in immune response GO:0002275 10 0.103
positive regulation of stress activated mapk cascade GO:0032874 60 0.103
anatomical structure formation involved in morphogenesis GO:0048646 284 0.103
regulation of cd4 positive alpha beta t cell activation GO:2000514 5 0.102
Mouse
behavior GO:0007610 112 0.101
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.101
blood vessel development GO:0001568 172 0.101
regulation of calcium ion transport GO:0051924 79 0.101
regulation of gtpase activity GO:0043087 180 0.099
regulation of rho gtpase activity GO:0032319 66 0.099
nucleoside triphosphate metabolic process GO:0009141 422 0.099
type 2 immune response GO:0042092 6 0.098
nucleoside phosphate catabolic process GO:1901292 412 0.098
regulation of alpha beta t cell activation GO:0046634 13 0.097
Mouse
cellular cation homeostasis GO:0030003 163 0.097
gtp catabolic process GO:0006184 237 0.096
cd4 positive or cd8 positive alpha beta t cell lineage commitment GO:0043369 1 0.096
cd4 positive alpha beta t cell activation GO:0035710 6 0.096
Mouse
regulation of behavior GO:0050795 82 0.096
regulation of epithelial cell proliferation GO:0050678 113 0.095
erk1 and erk2 cascade GO:0070371 104 0.095
somatic recombination of immunoglobulin gene segments GO:0016447 4 0.093
female gamete generation GO:0007292 2 0.093
eosinophil mediated immunity GO:0002447 2 0.092
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.091
purine nucleoside triphosphate catabolic process GO:0009146 392 0.090
mhc class ii biosynthetic process GO:0045342 4 0.089
regulation of nucleotide catabolic process GO:0030811 205 0.088
granulocyte chemotaxis GO:0071621 37 0.088
negative regulation of natural killer cell chemotaxis GO:2000502 1 0.087
negative regulation of lymphocyte migration GO:2000402 4 0.087
interleukin 8 mediated signaling pathway GO:0038112 2 0.086
regulation of metal ion transport GO:0010959 120 0.086
negative regulation of type 2 immune response GO:0002829 3 0.086
regulation of vasculature development GO:1901342 97 0.086
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.085
positive regulation of leukocyte mediated immunity GO:0002705 24 0.085
regulation of protein transport GO:0051223 213 0.084
jak stat cascade GO:0007259 46 0.084
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.084
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.084
sequestering of calcium ion GO:0051208 17 0.083
regulation of neutrophil chemotaxis GO:0090022 10 0.083
regulation of t helper 1 type immune response GO:0002825 5 0.083
chemical homeostasis GO:0048878 306 0.083
cell killing GO:0001906 34 0.082
second messenger mediated signaling GO:0019932 78 0.081
positive regulation of nucleoside metabolic process GO:0045979 186 0.081
negative regulation of leukocyte differentiation GO:1902106 24 0.081
stress activated protein kinase signaling cascade GO:0031098 94 0.081
b cell proliferation GO:0042100 22 0.080
regulation of cell motility GO:2000145 299 0.080
regulation of angiogenesis GO:0045765 92 0.079
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.079
positive regulation of myotube differentiation GO:0010831 3 0.079
regulation of b cell activation GO:0050864 24 0.078
Mouse
establishment of lymphocyte polarity GO:0001767 2 0.078
cellular chemical homeostasis GO:0055082 180 0.078
response to alcohol GO:0097305 64 0.078
positive regulation of nucleotide metabolic process GO:0045981 230 0.078
positive regulation of exocytosis GO:0045921 35 0.076
regulation of mast cell activation GO:0033003 5 0.076
positive regulation of astrocyte chemotaxis GO:2000464 1 0.075
purine ribonucleoside catabolic process GO:0046130 398 0.075
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.075
cardiovascular system development GO:0072358 262 0.074
angiogenesis GO:0001525 147 0.074
establishment of t cell polarity GO:0001768 2 0.074
cell development GO:0048468 328 0.074
positive regulation of cellular catabolic process GO:0031331 284 0.072
cation homeostasis GO:0055080 189 0.072
regulation of defense response GO:0031347 154 0.071
negative regulation of epithelial cell proliferation GO:0050680 48 0.071
neutrophil migration GO:1990266 25 0.071
regulation of protein complex assembly GO:0043254 147 0.070
signal transduction by phosphorylation GO:0023014 297 0.070
cd8 positive alpha beta t cell proliferation GO:0035740 1 0.070
regulation of rho protein signal transduction GO:0035023 79 0.070
regulation of exocytosis GO:0017157 46 0.070
t cell lineage commitment GO:0002360 1 0.070
taxis GO:0042330 157 0.069
cellular homeostasis GO:0019725 196 0.069
response to virus GO:0009615 126 0.069
divalent inorganic cation homeostasis GO:0072507 136 0.069
biological adhesion GO:0022610 331 0.068
defense response to other organism GO:0098542 129 0.067
negative regulation of leukocyte mediated immunity GO:0002704 14 0.067
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.067
lymphocyte apoptotic process GO:0070227 20 0.067
response to nitric oxide GO:0071731 4 0.066
positive regulation of behavior GO:0048520 60 0.066
eosinophil degranulation GO:0043308 2 0.066
positive regulation of isotype switching GO:0045830 2 0.066
negative regulation of biomineral tissue development GO:0070168 8 0.066
positive regulation of protein phosphorylation GO:0001934 313 0.066
regulation of striated muscle cell differentiation GO:0051153 25 0.066
oogenesis GO:0048477 2 0.065
positive regulation of cell migration GO:0030335 172 0.065
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.065
apoptotic signaling pathway GO:0097190 268 0.065
negative regulation of apoptotic signaling pathway GO:2001234 97 0.065
negative regulation of t cell activation GO:0050868 18 0.064
leukocyte degranulation GO:0043299 11 0.064
guanosine containing compound metabolic process GO:1901068 244 0.064
positive regulation of transferase activity GO:0051347 227 0.064
response to lipid GO:0033993 206 0.063
extrinsic apoptotic signaling pathway GO:0097191 119 0.063
regulation of protein localization GO:0032880 296 0.062
purine ribonucleotide catabolic process GO:0009154 404 0.062
response to abiotic stimulus GO:0009628 336 0.062
regulation of cytokine production involved in immune response GO:0002718 22 0.062
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.062
calcium ion transport GO:0006816 147 0.062
dendritic cell antigen processing and presentation GO:0002468 1 0.061
peptidyl tyrosine phosphorylation GO:0018108 170 0.061
positive regulation of mast cell activation GO:0033005 2 0.061
granzyme b production GO:0071613 1 0.061
regulation of purine nucleotide catabolic process GO:0033121 205 0.061
regulation of nucleoside metabolic process GO:0009118 209 0.060
positive regulation of macrophage chemotaxis GO:0010759 3 0.060
establishment of protein localization to organelle GO:0072594 172 0.059
response to bacterium GO:0009617 144 0.059
single organism cell adhesion GO:0098602 179 0.059
t cell activation involved in immune response GO:0002286 13 0.059
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.059
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.059
peptidyl tyrosine modification GO:0018212 170 0.058
positive regulation of cell death GO:0010942 263 0.057
regulation of mapk cascade GO:0043408 262 0.057
regulation of vesicle mediated transport GO:0060627 130 0.057
regulation of granzyme a production GO:2000511 1 0.057
negative regulation of cellular component movement GO:0051271 106 0.057
positive regulation of kinase activity GO:0033674 204 0.057
positive regulation of striated muscle cell differentiation GO:0051155 9 0.057
regulation of kinase activity GO:0043549 314 0.057
divalent inorganic cation transport GO:0072511 158 0.056
long term memory GO:0007616 2 0.056
dendritic cell differentiation GO:0097028 13 0.056
positive regulation of gtpase activity GO:0043547 166 0.056
regulated secretory pathway GO:0045055 20 0.056
cytosolic calcium ion transport GO:0060401 48 0.056
guanosine containing compound catabolic process GO:1901069 239 0.056
ribonucleoside catabolic process GO:0042454 406 0.056
regulation of protein kinase activity GO:0045859 289 0.055
dna recombination GO:0006310 77 0.055
cellular macromolecular complex assembly GO:0034622 324 0.055
response to organic cyclic compound GO:0014070 204 0.055
cellular lipid metabolic process GO:0044255 303 0.054
nucleoside triphosphate catabolic process GO:0009143 394 0.054
purine nucleoside triphosphate metabolic process GO:0009144 412 0.053
positive regulation of cd4 positive alpha beta t cell differentiation GO:0043372 2 0.053
Mouse
jnk cascade GO:0007254 80 0.052
regulation of cellular component size GO:0032535 82 0.052
cellular component morphogenesis GO:0032989 314 0.052
regulation of cell cycle GO:0051726 393 0.051
regulation of cellular amine metabolic process GO:0033238 11 0.051
regulation of locomotion GO:0040012 329 0.051
blastoderm segmentation GO:0007350 2 0.051
nucleoside catabolic process GO:0009164 408 0.051
regulation of astrocyte chemotaxis GO:2000458 1 0.051
secretion GO:0046903 254 0.050
positive regulation of calcium ion transport into cytosol GO:0010524 20 0.050
t cell migration GO:0072678 16 0.050
regulation of myotube differentiation GO:0010830 18 0.050
regulation of erk1 and erk2 cascade GO:0070372 99 0.050
regulation of calcium ion transport into cytosol GO:0010522 33 0.050
positive regulation of programmed cell death GO:0043068 249 0.050
positive regulation of catabolic process GO:0009896 310 0.049
positive regulation of apoptotic process GO:0043065 246 0.049
protein secretion GO:0009306 98 0.049
negative regulation of c c chemokine binding GO:2001264 1 0.049
regulation of small gtpase mediated signal transduction GO:0051056 156 0.048
actin polymerization or depolymerization GO:0008154 56 0.048
divalent metal ion transport GO:0070838 152 0.048
positive regulation of lymphocyte differentiation GO:0045621 13 0.048
Mouse
negative regulation of homeostatic process GO:0032845 59 0.048
response to hormone GO:0009725 175 0.048
regulation of gtp catabolic process GO:0033124 180 0.048
bone mineralization GO:0030282 34 0.048
positive regulation of protein complex assembly GO:0031334 86 0.048
positive regulation of dna metabolic process GO:0051054 73 0.048
regulation of sequestering of calcium ion GO:0051282 41 0.047
regulation of c c chemokine binding GO:2001263 1 0.047
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.047
Mouse
purine containing compound catabolic process GO:0072523 411 0.047
regulation of t cell mediated immunity GO:0002709 18 0.047
regulation of ras gtpase activity GO:0032318 128 0.046
nervous system development GO:0007399 293 0.046
regulation of cellular component biogenesis GO:0044087 281 0.046
regulation of ion transport GO:0043269 189 0.046
regulation of transferase activity GO:0051338 355 0.046
myeloid leukocyte differentiation GO:0002573 60 0.046
protein import GO:0017038 130 0.046
negative regulation of t cell apoptotic process GO:0070233 4 0.046
regulation of actin cytoskeleton organization GO:0032956 116 0.045
blood vessel morphogenesis GO:0048514 162 0.045
actin filament organization GO:0007015 128 0.045
positive regulation of myeloid cell differentiation GO:0045639 39 0.045
regulation of establishment of protein localization GO:0070201 242 0.045
negative regulation of bone mineralization GO:0030502 7 0.045
cell division GO:0051301 168 0.044
t cell selection GO:0045058 4 0.044
positive regulation of mapk cascade GO:0043410 190 0.044
organophosphate catabolic process GO:0046434 430 0.044
regulation of macrophage chemotaxis GO:0010758 4 0.043
positive regulation of cell adhesion GO:0045785 84 0.043
regulation of jnk cascade GO:0046328 73 0.043
positive regulation of regulated secretory pathway GO:1903307 8 0.042
viral process GO:0016032 146 0.042
cellular response to molecule of bacterial origin GO:0071219 62 0.042
epithelial cell proliferation GO:0050673 128 0.042
regulation of camp metabolic process GO:0030814 52 0.042
cytokine secretion GO:0050663 64 0.042
regulation of isotype switching GO:0045191 2 0.041
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.041
dephosphorylation GO:0016311 209 0.040
actin filament polymerization GO:0030041 45 0.040
regulation of ion homeostasis GO:2000021 73 0.040
positive regulation of rho gtpase activity GO:0032321 56 0.040
response to wounding GO:0009611 168 0.040
nuclear transport GO:0051169 179 0.040
regulation of myeloid leukocyte differentiation GO:0002761 39 0.040
cellular response to endogenous stimulus GO:0071495 336 0.040
cellular extravasation GO:0045123 21 0.040
positive regulation of organelle organization GO:0010638 195 0.040
positive t cell selection GO:0043368 2 0.039
regulation of cytokine secretion GO:0050707 57 0.039
regulation of anatomical structure size GO:0090066 101 0.039
leukocyte apoptotic process GO:0071887 31 0.038
post embryonic organ development GO:0048569 1 0.038
leukocyte cell cell adhesion GO:0007159 37 0.038
purine ribonucleoside metabolic process GO:0046128 437 0.038
positive regulation of cytoskeleton organization GO:0051495 83 0.038
purine nucleotide catabolic process GO:0006195 405 0.038
regulation of chemokine biosynthetic process GO:0045073 4 0.038
regulation of cell morphogenesis GO:0022604 153 0.038
transmembrane transport GO:0055085 399 0.037
endocytosis GO:0006897 159 0.037
regulation of cellular response to stress GO:0080135 244 0.037
protein targeting GO:0006605 187 0.037
muscle structure development GO:0061061 98 0.037
negative regulation of lymphocyte chemotaxis GO:1901624 2 0.037
regulation of dna metabolic process GO:0051052 153 0.037
positive regulation of angiogenesis GO:0045766 51 0.037
lymphocyte migration GO:0072676 28 0.037
lymphocyte chemotaxis GO:0048247 17 0.037
regulation of inflammatory response GO:0050727 46 0.036
lymphocyte activation involved in immune response GO:0002285 20 0.036
regulation of actin filament based process GO:0032970 141 0.036
protein localization to organelle GO:0033365 280 0.036
response to cholesterol GO:0070723 11 0.036
positive regulation of cellular component movement GO:0051272 181 0.036
system process GO:0003008 349 0.036
endothelial cell proliferation GO:0001935 65 0.035
response to tumor necrosis factor GO:0034612 76 0.035
regulation of lymphocyte chemotaxis GO:1901623 12 0.034
viral life cycle GO:0019058 132 0.034
regulation of chemokine production GO:0032642 31 0.034
positive regulation of granzyme b production GO:0071663 1 0.034
granzyme a production GO:0035746 1 0.034
negative regulation of sequestering of calcium ion GO:0051283 41 0.034
regulation of actin filament length GO:0030832 56 0.034
positive regulation of cellular component biogenesis GO:0044089 158 0.034
single organismal cell cell adhesion GO:0016337 148 0.034
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.033

IL2RG disease predictions

Disease DO term ID Size Probability Func Analog Org
acquired immunodeficiency syndrome DOID:635 13 0.261
disease by infectious agent DOID:0050117 34 0.261
viral infectious disease DOID:934 13 0.261
human immunodeficiency virus infectious disease DOID:526 13 0.261
immune system disease DOID:2914 155 0.037