IMP
Process View
alpha beta t cell activation involved in immune response
The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
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| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| IL4R | interleukin 4 receptor | 0.992 | Mouse | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.759 | Mouse | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.448 | ||
| NCOR2 | nuclear receptor corepressor 2 | 0.412 | ||
| STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.323 | Mouse | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.316 | ||
| RXRA | retinoid X receptor, alpha | 0.230 | ||
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.179 | ||
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.159 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.155 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.117 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.102 | ||
| IL4 | interleukin 4 | 0.082 | Mouse | |
| IL23A | interleukin 23, alpha subunit p19 | 0.071 | Mouse | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.064 | ||
| INPP5D | inositol polyphosphate-5-phosphatase, 145kDa | 0.046 | ||
| PDZD11 | PDZ domain containing 11 | 0.040 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.035 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.033 | ||
| LIN9 | lin-9 homolog (C. elegans) | 0.032 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.029 | Mouse | |
| SOCS3 | suppressor of cytokine signaling 3 | 0.027 | ||
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.017 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.015 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.014 | ||
| RARA | retinoic acid receptor, alpha | 0.013 | ||
| PLXND1 | plexin D1 | 0.011 | ||
| E2F1 | E2F transcription factor 1 | 0.010 |