Homo sapiens

107 known processes

IBTK

inhibitor of Bruton agammaglobulinemia tyrosine kinase

(Aliases: MGC142256,KIAA1417,BTKI,RP1-93K22.1,MGC142258)

IBTK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
azole transport GO:0045117 4 0.997
cellular amino acid metabolic process GO:0006520 116 0.494
oogenesis GO:0048477 2 0.405
multicellular organismal aging GO:0010259 3 0.385
endosomal transport GO:0016197 129 0.305
secretion GO:0046903 254 0.282
negative regulation of cellular amine metabolic process GO:0033239 3 0.275
regulation of cellular ketone metabolic process GO:0010565 50 0.272
determination of adult lifespan GO:0008340 2 0.270
cation transport GO:0006812 331 0.259
apoptotic signaling pathway GO:0097190 268 0.255
caveolin mediated endocytosis GO:0072584 4 0.248
female gamete generation GO:0007292 2 0.239
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.231
cellular lipid metabolic process GO:0044255 303 0.223
lipid metabolic process GO:0006629 381 0.206
amine metabolic process GO:0009308 44 0.203
cellular cation homeostasis GO:0030003 163 0.186
cellular divalent inorganic cation homeostasis GO:0072503 128 0.185
regulation of cellular amine metabolic process GO:0033238 11 0.182
cellular ketone metabolic process GO:0042180 80 0.175
regulation of proteolysis GO:0030162 293 0.166
response to transforming growth factor beta GO:0071559 94 0.161
salivary gland morphogenesis GO:0007435 4 0.161
ion homeostasis GO:0050801 230 0.150
negative regulation of programmed cell death GO:0043069 321 0.147
regulation of cell motility GO:2000145 299 0.145
protein maturation GO:0051604 233 0.138
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.137
purine nucleoside triphosphate catabolic process GO:0009146 392 0.134
nucleoside phosphate catabolic process GO:1901292 412 0.133
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.133
nitrogen compound transport GO:0071705 191 0.131
regulation of cell adhesion GO:0030155 166 0.128
single organism cellular localization GO:1902580 332 0.127
system process GO:0003008 349 0.126
negative regulation of protein metabolic process GO:0051248 391 0.123
regulation of vesicle mediated transport GO:0060627 130 0.123
purine ribonucleoside catabolic process GO:0046130 398 0.122
divalent inorganic cation homeostasis GO:0072507 136 0.119
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.119
cellular ion homeostasis GO:0006873 168 0.117
cytoplasmic transport GO:0016482 379 0.117
cellular response to oxidative stress GO:0034599 85 0.116
cell adhesion GO:0007155 325 0.116
positive regulation of hydrolase activity GO:0051345 331 0.115
protein processing GO:0016485 226 0.114
positive regulation of interferon gamma mediated signaling pathway GO:0060335 2 0.113
regulation of endopeptidase activity GO:0052548 170 0.113
response to oxygen containing compound GO:1901700 369 0.113
dna replication GO:0006260 116 0.112
protein oligomerization GO:0051259 173 0.112
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.111
cellular macromolecular complex assembly GO:0034622 324 0.108
post embryonic development GO:0009791 2 0.105
positive regulation of programmed cell death GO:0043068 249 0.105
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.105
positive regulation of cellular amine metabolic process GO:0033240 7 0.105
regulation of apoptotic signaling pathway GO:2001233 175 0.103
negative regulation of peptidase activity GO:0010466 91 0.102
actin cytoskeleton organization GO:0030036 207 0.102
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.101
positive regulation of innate immune response GO:0045089 79 0.101
nucleoside triphosphate metabolic process GO:0009141 422 0.101
regulation of cell migration GO:0030334 289 0.100
actin filament polymerization GO:0030041 45 0.100
chemical homeostasis GO:0048878 306 0.099
cellular amine metabolic process GO:0044106 41 0.099
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.098
cation homeostasis GO:0055080 189 0.098
nucleoside catabolic process GO:0009164 408 0.096
i kappab kinase nf kappab signaling GO:0007249 166 0.096
organophosphate catabolic process GO:0046434 430 0.095
positive regulation of lipid metabolic process GO:0045834 50 0.095
exocytosis GO:0006887 71 0.093
glycosyl compound catabolic process GO:1901658 413 0.093
positive regulation of cell death GO:0010942 263 0.093
purine ribonucleoside metabolic process GO:0046128 437 0.092
regulation of cellular amino acid metabolic process GO:0006521 6 0.091
purine ribonucleotide catabolic process GO:0009154 404 0.090
metal ion homeostasis GO:0055065 169 0.090
negative regulation of mitochondrial depolarization GO:0051902 2 0.089
cellular protein complex assembly GO:0043623 188 0.089
dephosphorylation GO:0016311 209 0.089
negative regulation of hydrolase activity GO:0051346 182 0.088
cellular response to reactive oxygen species GO:0034614 50 0.086
negative regulation of apoptotic process GO:0043066 316 0.085
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.084
membrane organization GO:0061024 292 0.083
negative regulation of apoptotic signaling pathway GO:2001234 97 0.082
positive regulation of proteolysis GO:0045862 142 0.081
response to fungus GO:0009620 4 0.081
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.080
regulation of secretion GO:0051046 194 0.080
regulation of peptide hormone secretion GO:0090276 41 0.080
regulation of lipid metabolic process GO:0019216 96 0.079
negative regulation of catalytic activity GO:0043086 335 0.078
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.078
intrinsic apoptotic signaling pathway GO:0097193 127 0.078
phospholipid metabolic process GO:0006644 99 0.078
negative regulation of cell death GO:0060548 345 0.078
hormone secretion GO:0046879 65 0.078
purine nucleotide catabolic process GO:0006195 405 0.078
negative regulation of endopeptidase activity GO:0010951 84 0.077
positive regulation of peptidase activity GO:0010952 88 0.076
protein homooligomerization GO:0051260 100 0.075
regulation of hormone levels GO:0010817 125 0.075
neurological system process GO:0050877 163 0.075
secretion by cell GO:0032940 226 0.074
epithelial cell migration GO:0010631 119 0.074
regulation of t cell activation GO:0050863 77 0.074
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.073
extrinsic apoptotic signaling pathway GO:0097191 119 0.073
peptidyl tyrosine phosphorylation GO:0018108 170 0.073
vesicle mediated transport GO:0016192 371 0.072
biological adhesion GO:0022610 331 0.072
anatomical structure formation involved in morphogenesis GO:0048646 284 0.071
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.071
regulation of protein oligomerization GO:0032459 26 0.070
purine nucleoside catabolic process GO:0006152 398 0.068
regulation of organelle assembly GO:1902115 40 0.066
cellular response to oxygen containing compound GO:1901701 276 0.066
regulation of cellular component movement GO:0051270 334 0.066
regulation of membrane potential GO:0042391 95 0.065
cellular response to endogenous stimulus GO:0071495 336 0.065
regulation of hormone secretion GO:0046883 57 0.064
positive regulation of transport GO:0051050 336 0.064
actin polymerization or depolymerization GO:0008154 56 0.064
protein polymerization GO:0051258 71 0.063
protein autophosphorylation GO:0046777 123 0.063
regulation of innate immune response GO:0045088 97 0.063
regulation of homeostatic process GO:0032844 121 0.062
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.062
response to oxidative stress GO:0006979 121 0.062
regulation of actin polymerization or depolymerization GO:0008064 56 0.061
regulation of cytoskeleton organization GO:0051493 177 0.061
regulation of ion homeostasis GO:2000021 73 0.061
positive regulation of apoptotic signaling pathway GO:2001235 70 0.061
positive regulation of hormone secretion GO:0046887 25 0.060
peptide hormone secretion GO:0030072 50 0.060
transition metal ion homeostasis GO:0055076 31 0.060
regulation of locomotion GO:0040012 329 0.060
regulation of secretion by cell GO:1903530 177 0.060
regulation of receptor mediated endocytosis GO:0048259 32 0.059
cellular response to acid chemical GO:0071229 44 0.058
cell projection organization GO:0030030 252 0.058
organelle assembly GO:0070925 176 0.058
regulation of membrane depolarization GO:0003254 19 0.058
single organism cell adhesion GO:0098602 179 0.058
integrin mediated signaling pathway GO:0007229 32 0.057
cellular metal ion homeostasis GO:0006875 146 0.056
regulation of cysteine type endopeptidase activity GO:2000116 127 0.056
regulation of lipid kinase activity GO:0043550 19 0.056
regulation of cellular component biogenesis GO:0044087 281 0.056
positive regulation of organelle organization GO:0010638 195 0.055
activation of cysteine type endopeptidase activity GO:0097202 57 0.055
positive regulation of secretion GO:0051047 116 0.055
negative regulation of intracellular signal transduction GO:1902532 183 0.055
mast cell activation involved in immune response GO:0002279 4 0.055
ribonucleoside triphosphate catabolic process GO:0009203 391 0.054
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.054
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.054
positive regulation of defense response GO:0031349 87 0.054
cellular response to growth factor stimulus GO:0071363 197 0.053
positive regulation of kinase activity GO:0033674 204 0.053
positive regulation of response to interferon gamma GO:0060332 2 0.053
negative regulation of proteolysis GO:0045861 132 0.053
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.052
regulation of protein kinase activity GO:0045859 289 0.052
positive regulation of cellular catabolic process GO:0031331 284 0.051
ribonucleotide catabolic process GO:0009261 405 0.051
cellular response to biotic stimulus GO:0071216 71 0.050
cellular transition metal ion homeostasis GO:0046916 21 0.050
hormone transport GO:0009914 68 0.050
early endosome to late endosome transport GO:0045022 21 0.049
regulation of cell differentiation GO:0045595 393 0.049
regulation of cell cell adhesion GO:0022407 57 0.049
negative regulation of cellular protein metabolic process GO:0032269 353 0.049
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.049
ribonucleoside triphosphate metabolic process GO:0009199 412 0.049
regulation of epithelial cell migration GO:0010632 93 0.048
aging GO:0007568 66 0.048
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.048
response to cytokine GO:0034097 232 0.047
positive regulation of secretion by cell GO:1903532 108 0.047
negative regulation of protein processing GO:0010955 142 0.047
positive regulation of cellular component organization GO:0051130 376 0.047
regulation of defense response GO:0031347 154 0.047
positive regulation of endopeptidase activity GO:0010950 84 0.047
response to reactive oxygen species GO:0000302 61 0.046
response to acid chemical GO:0001101 66 0.046
nucleotide catabolic process GO:0009166 408 0.045
purine nucleoside triphosphate metabolic process GO:0009144 412 0.045
positive regulation of apoptotic process GO:0043065 246 0.045
single organismal cell cell adhesion GO:0016337 148 0.044
peptide secretion GO:0002790 51 0.044
cellular component morphogenesis GO:0032989 314 0.044
cellular chemical homeostasis GO:0055082 180 0.044
regulation of gtp catabolic process GO:0033124 180 0.043
regulation of actin filament length GO:0030832 56 0.043
gtp catabolic process GO:0006184 237 0.043
t cell receptor signaling pathway GO:0050852 21 0.043
regulation of peptide secretion GO:0002791 42 0.042
zymogen activation GO:0031638 70 0.042
regulation of protein maturation GO:1903317 150 0.041
negative regulation of phosphorylation GO:0042326 174 0.041
regulation of protein processing GO:0070613 150 0.041
response to growth factor GO:0070848 205 0.041
modification dependent protein catabolic process GO:0019941 209 0.041
regulation of purine nucleotide catabolic process GO:0033121 205 0.040
regulation of anatomical structure morphogenesis GO:0022603 286 0.040
purine containing compound catabolic process GO:0072523 411 0.040
defense response GO:0006952 315 0.040
actin filament based process GO:0030029 224 0.040
single organism reproductive process GO:0044702 98 0.040
positive regulation of nucleoside metabolic process GO:0045979 186 0.039
negative regulation of protein modification process GO:0031400 200 0.039
positive regulation of phosphorylation GO:0042327 394 0.039
protein localization to membrane GO:0072657 160 0.039
cell morphogenesis GO:0000902 296 0.039
negative regulation of anoikis GO:2000811 15 0.038
protein modification by small protein conjugation GO:0032446 342 0.038
mast cell degranulation GO:0043303 4 0.038
chromatin modification GO:0016568 298 0.038
negative regulation of cellular component organization GO:0051129 235 0.037
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.037
regulation of transferase activity GO:0051338 355 0.037
cellular protein catabolic process GO:0044257 261 0.037
regulation of protein polymerization GO:0032271 63 0.036
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.036
peptide transport GO:0015833 74 0.036
ribonucleoside catabolic process GO:0042454 406 0.036
nucleoside triphosphate catabolic process GO:0009143 394 0.036
positive regulation of nucleotide catabolic process GO:0030813 185 0.036
gtp metabolic process GO:0046039 239 0.036
negative regulation of protein maturation GO:1903318 142 0.036
positive regulation of cell development GO:0010720 92 0.035
innate immune response GO:0045087 178 0.035
immune response GO:0006955 307 0.035
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.035
amide transport GO:0042886 76 0.035
intracellular protein transport GO:0006886 270 0.035
insulin secretion GO:0030073 39 0.035
regulation of kinase activity GO:0043549 314 0.034
establishment of protein localization to membrane GO:0090150 121 0.034
positive regulation of gtpase activity GO:0043547 166 0.034
positive regulation of nucleotide metabolic process GO:0045981 230 0.034
regulation of immune response GO:0050776 201 0.034
regulation of actin cytoskeleton organization GO:0032956 116 0.034
nervous system development GO:0007399 293 0.033
cellular response to interferon gamma GO:0071346 24 0.033
tissue migration GO:0090130 119 0.033
modification dependent macromolecule catabolic process GO:0043632 212 0.033
cell cell signaling GO:0007267 155 0.033
stress fiber assembly GO:0043149 40 0.032
positive regulation of cell proliferation GO:0008284 301 0.032
negative regulation of phosphorus metabolic process GO:0010563 267 0.032
guanosine containing compound metabolic process GO:1901068 244 0.031
protein kinase b signaling GO:0043491 69 0.031
positive regulation of gtp catabolic process GO:0033126 166 0.030
protein ubiquitination GO:0016567 314 0.030
enzyme linked receptor protein signaling pathway GO:0007167 303 0.030
endocytosis GO:0006897 159 0.030
cellular macromolecule catabolic process GO:0044265 380 0.030
epithelium migration GO:0090132 119 0.030
chromatin organization GO:0006325 351 0.029
regulation of caveolin mediated endocytosis GO:2001286 2 0.029
regulation of nervous system development GO:0051960 88 0.029
jak stat cascade GO:0007259 46 0.029
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.029
regulation of intracellular transport GO:0032386 195 0.029
response to external biotic stimulus GO:0043207 261 0.029
regulation of actin filament polymerization GO:0030833 50 0.028
negative regulation of kinase activity GO:0033673 106 0.028
negative regulation of transferase activity GO:0051348 124 0.028
single organism membrane organization GO:0044802 268 0.028
positive regulation of transferase activity GO:0051347 227 0.028
golgi vesicle transport GO:0048193 80 0.028
regulation of purine nucleotide metabolic process GO:1900542 264 0.028
response to interleukin 1 GO:0070555 47 0.028
negative regulation of phosphate metabolic process GO:0045936 267 0.028
positive regulation of catabolic process GO:0009896 310 0.028
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.027
cellular homeostasis GO:0019725 196 0.027
response to organonitrogen compound GO:0010243 156 0.027
regulation of peptide transport GO:0090087 62 0.027
regulation of cell morphogenesis GO:0022604 153 0.027
cellular response to cytokine stimulus GO:0071345 181 0.027
regulation of cytoplasmic transport GO:1903649 149 0.027
regulation of protein complex assembly GO:0043254 147 0.027
tyrosine phosphorylation of stat protein GO:0007260 33 0.027
protein catabolic process GO:0030163 325 0.026
response to nitrogen compound GO:1901698 184 0.026
response to lipid GO:0033993 206 0.026
positive regulation of insulin secretion GO:0032024 10 0.026
positive regulation of cytokine production GO:0001819 167 0.026
positive regulation of cytoskeleton organization GO:0051495 83 0.026
leukocyte differentiation GO:0002521 98 0.026
guanosine containing compound catabolic process GO:1901069 239 0.026
regulation of nucleotide catabolic process GO:0030811 205 0.025
response to drug GO:0042493 81 0.025
cellular response to lipid GO:0071396 127 0.025
regulation of endocytosis GO:0030100 72 0.025
positive regulation of developmental process GO:0051094 314 0.025
actin filament bundle organization GO:0061572 54 0.025
cytokine production GO:0001816 247 0.025
response to biotic stimulus GO:0009607 276 0.025
regulation of protein localization GO:0032880 296 0.025
regulation of protein tyrosine kinase activity GO:0061097 36 0.025
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.024
reproductive process GO:0022414 106 0.024
immune response activating signal transduction GO:0002757 90 0.024
activation of immune response GO:0002253 114 0.024
protein localization to plasma membrane GO:0072659 93 0.024
regulation of cell activation GO:0050865 125 0.024
actomyosin structure organization GO:0031032 59 0.024
proteasomal protein catabolic process GO:0010498 176 0.024
cation transmembrane transport GO:0098655 238 0.024
regulation of nucleotide metabolic process GO:0006140 269 0.024
generation of neurons GO:0048699 152 0.023
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 0.023
positive regulation of peptide hormone secretion GO:0090277 15 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.023
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.022
regulation of cell projection organization GO:0031344 107 0.022
positive regulation of cell differentiation GO:0045597 211 0.022
positive regulation of immune response GO:0050778 159 0.022
neuron development GO:0048666 113 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.022
regulation of protein homooligomerization GO:0032462 11 0.022
ion transmembrane transport GO:0034220 338 0.021
cellular zinc ion homeostasis GO:0006882 10 0.021
regulation of protein kinase b signaling GO:0051896 61 0.021
ameboidal type cell migration GO:0001667 135 0.021
gland morphogenesis GO:0022612 8 0.021
cardiovascular system development GO:0072358 262 0.021
antigen receptor mediated signaling pathway GO:0050851 38 0.021
positive regulation of t cell activation GO:0050870 54 0.020
positive regulation of protein kinase b signaling GO:0051897 42 0.020
hindbrain development GO:0030902 3 0.020
positive regulation of protein phosphorylation GO:0001934 313 0.020
organ morphogenesis GO:0009887 147 0.020
regulation of body fluid levels GO:0050878 99 0.020
ras protein signal transduction GO:0007265 73 0.020
positive regulation of immune system process GO:0002684 283 0.020
negative regulation of protein complex assembly GO:0031333 43 0.020
blood coagulation GO:0007596 76 0.020
regulation of cytokine mediated signaling pathway GO:0001959 41 0.020
hemopoiesis GO:0030097 180 0.020
regulation of actin filament based process GO:0032970 141 0.019
peptidyl tyrosine modification GO:0018212 170 0.019
actin filament organization GO:0007015 128 0.019
cell growth GO:0016049 160 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
regulation of peptidase activity GO:0052547 180 0.019
positive regulation of neuron projection development GO:0010976 34 0.019
t cell activation GO:0042110 99 0.019
protein targeting GO:0006605 187 0.019
regulation of neuron projection development GO:0010975 57 0.019
monocarboxylic acid metabolic process GO:0032787 185 0.019
cell activation involved in immune response GO:0002263 30 0.019
organic anion transport GO:0015711 103 0.019
negative regulation of protein tyrosine kinase activity GO:0061099 13 0.019
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.018
positive regulation of lymphocyte activation GO:0051251 73 0.018
epithelium development GO:0060429 227 0.018
leukocyte mediated immunity GO:0002443 59 0.018
organonitrogen compound biosynthetic process GO:1901566 200 0.018
regulation of mitochondrial depolarization GO:0051900 6 0.018
regulation of cytokine production GO:0001817 232 0.018
actin filament bundle assembly GO:0051017 54 0.018
developmental process involved in reproduction GO:0003006 66 0.018
wound healing GO:0042060 115 0.018
regulation of gtpase activity GO:0043087 180 0.017
positive regulation of cell projection organization GO:0031346 64 0.017
metencephalon development GO:0022037 2 0.017
behavior GO:0007610 112 0.017
tyrosine phosphorylation of stat3 protein GO:0042503 20 0.017
ubiquitin dependent protein catabolic process GO:0006511 206 0.017
regulation of response to cytokine stimulus GO:0060759 46 0.017
regulation of endothelial cell migration GO:0010594 67 0.017
interferon gamma production GO:0032609 39 0.017
neuron differentiation GO:0030182 138 0.017
cell cycle dna replication GO:0044786 11 0.017
regulation of neuron differentiation GO:0045664 70 0.016
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.016
cellular carbohydrate metabolic process GO:0044262 84 0.016
positive regulation of cell migration GO:0030335 172 0.016
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.016
immune effector process GO:0002252 159 0.016
regulation of vasculature development GO:1901342 97 0.016
peptidyl serine phosphorylation GO:0018105 101 0.016
sulfur compound metabolic process GO:0006790 101 0.016
ossification GO:0001503 121 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
mitotic cell cycle GO:0000278 326 0.016
histone modification GO:0016570 251 0.016
transmembrane transport GO:0055085 399 0.016
positive regulation of gliogenesis GO:0014015 4 0.016
mitotic cell cycle process GO:1903047 286 0.016
spermatid differentiation GO:0048515 4 0.015
cell cycle phase transition GO:0044770 173 0.015
embryonic epithelial tube formation GO:0001838 4 0.015
peptidyl tyrosine autophosphorylation GO:0038083 5 0.015
response to other organism GO:0051707 261 0.015
protein localization to organelle GO:0033365 280 0.015
small molecule biosynthetic process GO:0044283 157 0.015
reactive oxygen species metabolic process GO:0072593 75 0.015
oocyte development GO:0048599 1 0.015
covalent chromatin modification GO:0016569 254 0.015
mrna metabolic process GO:0016071 175 0.015
inositol lipid mediated signaling GO:0048017 55 0.015
dna repair GO:0006281 198 0.015
actin cytoskeleton reorganization GO:0031532 37 0.015
regulation of cell cycle GO:0051726 393 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.015
growth GO:0040007 202 0.015
cellular response to organonitrogen compound GO:0071417 124 0.015
regulation of interferon gamma mediated signaling pathway GO:0060334 6 0.015
neuronal action potential GO:0019228 9 0.015
positive regulation of neuron differentiation GO:0045666 40 0.015
phosphatidylinositol mediated signaling GO:0048015 55 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.014
inorganic ion transmembrane transport GO:0098660 231 0.014
regulation of lymphocyte activation GO:0051249 103 0.014
regulation of angiogenesis GO:0045765 92 0.014
negative regulation of protein kinase activity GO:0006469 98 0.014
epithelial cell proliferation GO:0050673 128 0.014
immune system development GO:0002520 195 0.014
mapk cascade GO:0000165 288 0.014
organelle localization GO:0051640 84 0.014
neuromuscular junction development GO:0007528 3 0.014
regulation of cell cycle process GO:0010564 266 0.014
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.014
leukocyte activation GO:0045321 164 0.014
positive regulation of cell adhesion GO:0045785 84 0.014
positive regulation of lipid kinase activity GO:0090218 13 0.014
regulation of leukocyte activation GO:0002694 115 0.014
regulation of response to interferon gamma GO:0060330 7 0.013
spermatid development GO:0007286 4 0.013
golgi organization GO:0007030 38 0.013
regulated secretory pathway GO:0045055 20 0.013
cell division GO:0051301 168 0.013
embryo development GO:0009790 123 0.013
peptidyl serine modification GO:0018209 106 0.013
regulation of multi organism process GO:0043900 157 0.013
morphogenesis of embryonic epithelium GO:0016331 4 0.013
immune response regulating signaling pathway GO:0002764 97 0.013
tissue regeneration GO:0042246 3 0.013
negative regulation of protein oligomerization GO:0032460 8 0.013
inorganic cation transmembrane transport GO:0098662 194 0.013
response to wounding GO:0009611 168 0.013
segmentation GO:0035282 4 0.013
regulation of cell division GO:0051302 116 0.013
regulation of protein transport GO:0051223 213 0.013
locomotory behavior GO:0007626 1 0.013
cell projection morphogenesis GO:0048858 129 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
regulation of response to external stimulus GO:0032101 222 0.013
positive regulation of intracellular transport GO:0032388 104 0.013
positive regulation of response to external stimulus GO:0032103 88 0.012
cell projection assembly GO:0030031 126 0.012
memory GO:0007613 3 0.012
podosome assembly GO:0071800 6 0.012
response to radiation GO:0009314 151 0.012
morphogenesis of a polarized epithelium GO:0001738 3 0.012
regulation of interferon gamma production GO:0032649 36 0.012
multicellular organismal signaling GO:0035637 34 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
tor signaling GO:0031929 39 0.012
lipid biosynthetic process GO:0008610 177 0.012
anion transport GO:0006820 161 0.012
maintenance of location GO:0051235 112 0.012
regulation of protein catabolic process GO:0042176 155 0.012
divalent inorganic cation transport GO:0072511 158 0.012
regulation of anoikis GO:2000209 19 0.012
positive regulation of protein kinase activity GO:0045860 190 0.012
muscle structure development GO:0061061 98 0.012
receptor mediated endocytosis GO:0006898 84 0.012
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.012
response to retinoic acid GO:0032526 33 0.012

IBTK disease predictions

Disease DO term ID Size Probability Func Analog Org
blood protein disease DOID:620 16 0.369
immune system disease DOID:2914 155 0.369
hematopoietic system disease DOID:74 100 0.369
primary immunodeficiency disease DOID:612 36 0.188
agammaglobulinemia DOID:2583 16 0.188
b cell deficiency DOID:2115 17 0.188
disease of metabolism DOID:0014667 295 0.025
musculoskeletal system disease DOID:17 223 0.023
inherited metabolic disorder DOID:655 242 0.022
disease of cellular proliferation DOID:14566 174 0.013
sensory system disease DOID:0050155 203 0.012
nervous system disease DOID:863 431 0.012