Process View
16 genes annotated in human
DOID:2583
A B cell deficiency that is caused by a reduction in all types of gamma globulins.

In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "agammaglobulinemia"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 1.000 | Human | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.999 | Human | |
| CD79A | CD79a molecule, immunoglobulin-associated alpha | 0.964 | ||
| BTK | Bruton agammaglobulinemia tyrosine kinase | 0.931 | ||
| RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.877 | Human | |
| CD19 | CD19 molecule | 0.792 | ||
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.461 | ||
| CD79B | CD79b molecule, immunoglobulin-associated beta | 0.446 | ||
| CD22 | CD22 molecule | 0.412 | ||
| BLNK | B-cell linker | 0.322 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.246 | Human | |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.188 | ||
| CDCP1 | CUB domain containing protein 1 | 0.146 | ||
| TRIM9 | tripartite motif containing 9 | 0.134 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.116 | ||
| PRKCB | protein kinase C, beta | 0.089 | ||
| NCF1 | neutrophil cytosolic factor 1 | 0.088 | ||
| INO80B | INO80 complex subunit B | 0.081 | ||
| BCL3 | B-cell CLL/lymphoma 3 | 0.076 | ||
| CD9 | CD9 molecule | 0.073 | Human | |
| TCL1A | T-cell leukemia/lymphoma 1A | 0.070 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.049 | ||
| SPIB | Spi-B transcription factor (Spi-1/PU.1 related) | 0.042 | ||
| SYK | spleen tyrosine kinase | 0.042 | ||
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.041 | ||
| MZB1 | marginal zone B and B1 cell-specific protein | 0.040 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.037 | ||
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.036 | ||
| BLK | B lymphoid tyrosine kinase | 0.036 | Human | |
| PNOC | prepronociceptin | 0.034 | ||
| TSPAN4 | tetraspanin 4 | 0.034 | ||
| VPREB3 | pre-B lymphocyte 3 | 0.033 | ||
| POU2AF1 | POU class 2 associating factor 1 | 0.033 | ||
| IGL@ | immunoglobulin lambda locus | 0.027 | ||
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | 0.024 | ||
| MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.023 | ||
| TNIP2 | TNFAIP3 interacting protein 2 | 0.022 | ||
| CD72 | CD72 molecule | 0.022 | ||
| TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.021 | ||
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.021 | ||
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.020 | ||
| FLNA | filamin A, alpha | 0.018 | ||
| RHOH | ras homolog gene family, member H | 0.018 | ||
| CD99 | CD99 molecule | 0.018 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.017 | ||
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.017 | ||
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.015 | ||
| CXCR5 | chemokine (C-X-C motif) receptor 5 | 0.015 | ||
| SIN3A | SIN3 homolog A, transcription regulator (yeast) | 0.014 | ||
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | 0.013 | ||
| CD2AP | CD2-associated protein | 0.012 | ||
| CHUK | conserved helix-loop-helix ubiquitous kinase | 0.012 | ||
| SIT1 | signaling threshold regulating transmembrane adaptor 1 | 0.011 | ||
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 | 0.011 | ||
| ACTB | actin, beta | 0.011 | ||
| CD151 | CD151 molecule (Raph blood group) | 0.010 | ||
| IGLL1 | immunoglobulin lambda-like polypeptide 1 | 0.008 | ||
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.007 | ||
| CR2 | complement component (3d/Epstein Barr virus) receptor 2 | 0.007 | ||
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B | 0.003 | ||
| ICOS | inducible T-cell co-stimulator | 0.003 | ||
| LRRC8A | leucine rich repeat containing 8 family, member A | 0.002 | ||
| TNFRSF13C | tumor necrosis factor receptor superfamily, member 13C | 0.002 | ||
| CD81 | CD81 molecule | 0.001 | ||
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.001 | ||
| PRKCD | protein kinase C, delta | 0.001 | ||
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.000 |