|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
1.000
|
Fly |
|
|
canonical wnt signaling pathway involved in heart development
|
GO:0061316 |
3 |
0.997
|
|
|
|
heart formation
|
GO:0060914 |
2 |
0.994
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.993
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.988
|
Human Fly |
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.985
|
Human Zebrafish Mouse |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.983
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.964
|
|
|
|
heart field specification
|
GO:0003128 |
2 |
0.959
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.951
|
Human Zebrafish Mouse |
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.949
|
Mouse |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.940
|
Mouse Fly |
|
|
regulation of heart induction
|
GO:0090381 |
2 |
0.935
|
|
|
|
cardiac cell fate specification
|
GO:0060912 |
1 |
0.923
|
|
|
|
heart induction
|
GO:0003129 |
4 |
0.908
|
|
|
|
negative regulation of cell fate commitment
|
GO:0010454 |
3 |
0.901
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.901
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.896
|
|
|
|
canonical wnt signaling pathway involved in regulation of cell proliferation
|
GO:0044340 |
2 |
0.894
|
|
|
|
negative regulation of heart induction by canonical wnt signaling pathway
|
GO:0003136 |
1 |
0.889
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.876
|
|
|
|
specification of organ identity
|
GO:0010092 |
3 |
0.870
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.863
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.854
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.849
|
Human Mouse |
|
|
protein import
|
GO:0017038 |
130 |
0.846
|
Human Mouse |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.842
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.837
|
Mouse Fly |
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.829
|
Human Mouse |
|
|
neural tube formation
|
GO:0001841 |
3 |
0.828
|
|
|
|
non canonical wnt signaling pathway
|
GO:0035567 |
14 |
0.819
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.815
|
Human Mouse |
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.813
|
Mouse |
|
|
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
|
GO:1901030 |
3 |
0.812
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.806
|
Human Mouse |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.802
|
Mouse Rat |
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.801
|
Human Mouse |
|
|
post embryonic development
|
GO:0009791 |
2 |
0.799
|
Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.792
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.788
|
Mouse |
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.788
|
|
|
|
regulation of organ formation
|
GO:0003156 |
4 |
0.782
|
|
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.781
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.769
|
Zebrafish Mouse |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.768
|
Human Mouse |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.763
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.760
|
Human Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.760
|
Fly |
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.747
|
Human Mouse |
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.735
|
Human Mouse |
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.735
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.714
|
|
|
|
regulation of cardioblast differentiation
|
GO:0051890 |
4 |
0.714
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.714
|
Mouse Rat |
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.708
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.699
|
Mouse Rat |
|
|
epithelium development
|
GO:0060429 |
227 |
0.698
|
Zebrafish |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.695
|
Mouse Rat |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.692
|
Zebrafish Mouse |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.692
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.685
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.680
|
Zebrafish Mouse |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.679
|
Human |
|
|
negative regulation of cell fate specification
|
GO:0009996 |
3 |
0.667
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.666
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.653
|
Human Mouse Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.652
|
Mouse Rat |
|
|
negative regulation of canonical wnt signaling pathway
|
GO:0090090 |
55 |
0.649
|
Human Zebrafish Mouse |
|
|
heart development
|
GO:0007507 |
95 |
0.648
|
Fly |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.644
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.643
|
Mouse |
|
|
establishment of epithelial cell polarity
|
GO:0090162 |
2 |
0.643
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.636
|
Human Mouse |
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.633
|
Fly |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.627
|
Mouse |
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.626
|
Human Mouse |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.619
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.618
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.616
|
Human |
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.616
|
Mouse Rat |
|
|
taxis
|
GO:0042330 |
157 |
0.614
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.610
|
Human |
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.605
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.604
|
Fly |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.603
|
Mouse |
|
|
endodermal cell fate specification
|
GO:0001714 |
4 |
0.602
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.600
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.599
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.594
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.594
|
Human |
|
|
cardioblast cell fate specification
|
GO:0042685 |
1 |
0.583
|
|
|
|
canonical wnt signaling pathway involved in negative regulation of apoptotic process
|
GO:0044336 |
2 |
0.580
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.579
|
Zebrafish Mouse |
|
|
neural tube development
|
GO:0021915 |
9 |
0.577
|
|
|
|
positive regulation of neural precursor cell proliferation
|
GO:2000179 |
2 |
0.568
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.564
|
Zebrafish Mouse Fly |
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.564
|
Human Mouse |
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.563
|
Human Mouse |
|
|
regulation of stem cell differentiation
|
GO:2000736 |
56 |
0.562
|
Human |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.553
|
Human Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.553
|
|
|
|
regulation of heart morphogenesis
|
GO:2000826 |
4 |
0.545
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.540
|
|
|
|
negative regulation of cardioblast cell fate specification
|
GO:0009997 |
1 |
0.540
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.538
|
Mouse |
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.536
|
Mouse Rat |
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.534
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.532
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.530
|
Zebrafish |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.529
|
Mouse Rat |
|
|
establishment of monopolar cell polarity
|
GO:0061162 |
1 |
0.529
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.528
|
Human Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.523
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.522
|
|
|
|
ventricular septum morphogenesis
|
GO:0060412 |
3 |
0.521
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.518
|
Zebrafish Mouse |
|
|
nuclear import
|
GO:0051170 |
106 |
0.513
|
Human Mouse |
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.512
|
Human Mouse |
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.507
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.505
|
|
|
|
negative regulation of cardioblast differentiation
|
GO:0051892 |
2 |
0.500
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.497
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.495
|
Human Mouse |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.493
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.485
|
Human |
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.484
|
Zebrafish Mouse |
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.484
|
Zebrafish Mouse |
|
|
epithelial to mesenchymal transition
|
GO:0001837 |
48 |
0.483
|
Human |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.478
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.476
|
Human Zebrafish Fly |
|
|
positive regulation of protein export from nucleus
|
GO:0046827 |
6 |
0.473
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.472
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.464
|
|
|
|
cochlea development
|
GO:0090102 |
1 |
0.462
|
|
|
|
pituitary gland development
|
GO:0021983 |
2 |
0.449
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.449
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.444
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.443
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.440
|
Human Mouse |
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.437
|
Human Mouse |
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.436
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.433
|
|
|
|
spindle organization
|
GO:0007051 |
53 |
0.423
|
|
|
|
negative regulation of cytoplasmic transport
|
GO:1903650 |
46 |
0.419
|
Human |
|
|
mesenchymal cell development
|
GO:0014031 |
50 |
0.417
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.416
|
Mouse Rat |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.414
|
|
|
|
cardioblast cell fate commitment
|
GO:0042684 |
1 |
0.411
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.409
|
|
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.404
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.402
|
|
|
|
response to lithium ion
|
GO:0010226 |
2 |
0.402
|
|
|
|
growth
|
GO:0040007 |
202 |
0.400
|
Zebrafish |
|
|
regulation of organ morphogenesis
|
GO:2000027 |
24 |
0.400
|
|
|
|
regulation of cardiac cell fate specification
|
GO:2000043 |
1 |
0.397
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.396
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.394
|
Zebrafish |
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.393
|
|
|
|
stem cell maintenance
|
GO:0019827 |
19 |
0.393
|
Fly |
|
|
protein export from nucleus
|
GO:0006611 |
29 |
0.389
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.386
|
Zebrafish Mouse |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.382
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.382
|
|
|
|
wnt signaling pathway involved in heart development
|
GO:0003306 |
5 |
0.380
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.377
|
Human |
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.373
|
Human Mouse |
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.372
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.365
|
Human Mouse |
|
|
establishment or maintenance of monopolar cell polarity
|
GO:0061339 |
1 |
0.364
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.363
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.363
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.362
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.362
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.361
|
Mouse |
|
|
endodermal cell fate commitment
|
GO:0001711 |
4 |
0.357
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.357
|
Zebrafish Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.351
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.350
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.347
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.347
|
Fly |
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.345
|
Human |
|
|
vasculature development
|
GO:0001944 |
181 |
0.344
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.344
|
|
|
|
regulation of jun kinase activity
|
GO:0043506 |
27 |
0.343
|
Zebrafish Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.343
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.342
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.341
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.337
|
Human Zebrafish Mouse Fly |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.335
|
|
|
|
organ induction
|
GO:0001759 |
4 |
0.329
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.325
|
Human |
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.317
|
Zebrafish Mouse |
|
|
tube closure
|
GO:0060606 |
3 |
0.317
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.314
|
|
|
|
forebrain development
|
GO:0030900 |
26 |
0.314
|
Zebrafish |
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.311
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.310
|
Human Mouse |
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.309
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.309
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.308
|
Mouse |
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.307
|
Mouse |
|
|
chromatin modification
|
GO:0016568 |
298 |
0.307
|
|
|
|
negative regulation of epithelial cell proliferation
|
GO:0050680 |
48 |
0.304
|
|
|
|
negative regulation of stem cell differentiation
|
GO:2000737 |
22 |
0.304
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.301
|
Mouse Rat |
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.301
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.297
|
Human Zebrafish Mouse |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.297
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.294
|
|
|
|
negative regulation of heart induction
|
GO:1901320 |
1 |
0.294
|
|
|
|
establishment or maintenance of epithelial cell apical basal polarity
|
GO:0045197 |
1 |
0.289
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.288
|
Human |
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.287
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.282
|
Zebrafish Mouse |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.282
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.278
|
Zebrafish |
|
|
behavior
|
GO:0007610 |
112 |
0.277
|
Mouse |
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.273
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.272
|
Zebrafish Mouse |
|
|
forelimb morphogenesis
|
GO:0035136 |
4 |
0.270
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.267
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.266
|
Zebrafish |
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.266
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.265
|
Mouse Rat |
|
|
cerebral cortex development
|
GO:0021987 |
10 |
0.265
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.265
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.258
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.257
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.254
|
Zebrafish Mouse |
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.254
|
Human |
|
|
nuclear export
|
GO:0051168 |
69 |
0.252
|
|
|
|
cerebral cortex cell migration
|
GO:0021795 |
3 |
0.252
|
|
|
|
cardiocyte differentiation
|
GO:0035051 |
23 |
0.249
|
|
|
|
catenin import into nucleus
|
GO:0035411 |
18 |
0.248
|
Human Mouse |
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.245
|
|
|
|
establishment or maintenance of bipolar cell polarity
|
GO:0061245 |
2 |
0.242
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.240
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.239
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.239
|
|
|
|
establishment of tissue polarity
|
GO:0007164 |
3 |
0.237
|
|
|
|
establishment or maintenance of apical basal cell polarity
|
GO:0035088 |
2 |
0.237
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.236
|
Human |
|
|
cardiac septum morphogenesis
|
GO:0060411 |
9 |
0.234
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.233
|
Mouse |
|
|
regulation of catenin import into nucleus
|
GO:0035412 |
18 |
0.231
|
Human Mouse |
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.227
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.225
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.222
|
Human |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.218
|
Mouse |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.217
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.214
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.214
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.213
|
Human |
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.213
|
|
|
|
mesenchymal cell differentiation
|
GO:0048762 |
52 |
0.212
|
Human |
|
|
regulation of ubiquitin protein transferase activity
|
GO:0051438 |
28 |
0.211
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.211
|
|
|
|
establishment of apical basal cell polarity
|
GO:0035089 |
1 |
0.208
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.208
|
Human |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.206
|
|
|
|
negative regulation of protein binding
|
GO:0032091 |
35 |
0.206
|
|
|
|
cerebral cortex radially oriented cell migration
|
GO:0021799 |
1 |
0.205
|
|
|
|
negative regulation of cardiac cell fate specification
|
GO:2000044 |
1 |
0.204
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.204
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.203
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.201
|
Human |
|
|
regulation of growth
|
GO:0040008 |
165 |
0.200
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.199
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.197
|
Zebrafish |
|
|
morphogenesis of a polarized epithelium
|
GO:0001738 |
3 |
0.194
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.193
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.193
|
|
|
|
organ formation
|
GO:0048645 |
3 |
0.192
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.191
|
Mouse |
|
|
outflow tract septum morphogenesis
|
GO:0003148 |
4 |
0.191
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.189
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.189
|
|
|
|
non canonical wnt signaling pathway via mapk cascade
|
GO:0038030 |
4 |
0.187
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.187
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.187
|
Zebrafish Mouse |
|
|
negative regulation of cardiac muscle cell differentiation
|
GO:2000726 |
3 |
0.186
|
|
|
|
negative regulation of nucleocytoplasmic transport
|
GO:0046823 |
37 |
0.186
|
Human |
|
|
hindlimb morphogenesis
|
GO:0035137 |
2 |
0.182
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.182
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.180
|
Mouse |
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.180
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.179
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.178
|
Zebrafish Mouse |
|
|
negative regulation of protein import into nucleus
|
GO:0042308 |
30 |
0.176
|
Human |
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.175
|
Zebrafish Mouse |
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.175
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.174
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.174
|
Zebrafish |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.173
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.173
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.173
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.172
|
Zebrafish Mouse |
|
|
negative regulation of protein localization to nucleus
|
GO:1900181 |
34 |
0.172
|
Human |
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.171
|
Mouse |
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.171
|
|
|
|
negative regulation of jnk cascade
|
GO:0046329 |
16 |
0.170
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.169
|
Mouse |
|
|
postsynaptic membrane organization
|
GO:0001941 |
2 |
0.169
|
|
|
|
negative regulation of intracellular transport
|
GO:0032387 |
60 |
0.168
|
Human |
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.166
|
|
|
|
axis elongation
|
GO:0003401 |
4 |
0.165
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.164
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.164
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.163
|
Human Mouse |
|
|
protein acylation
|
GO:0043543 |
138 |
0.163
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.162
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.162
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.158
|
|
|
|
system process
|
GO:0003008 |
349 |
0.158
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.157
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.156
|
|
|
|
negative regulation of stress activated protein kinase signaling cascade
|
GO:0070303 |
19 |
0.153
|
|
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.152
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.152
|
|
|
|
inositol phosphate mediated signaling
|
GO:0048016 |
16 |
0.151
|
|
|
|
establishment of planar polarity
|
GO:0001736 |
3 |
0.151
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.149
|
|
|
|
renal vesicle development
|
GO:0072087 |
4 |
0.148
|
|
|
|
cell fate commitment involved in formation of primary germ layer
|
GO:0060795 |
6 |
0.147
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.147
|
|
|
|
regulation of microtubule based process
|
GO:0032886 |
74 |
0.147
|
|
|
|
regulation of heart growth
|
GO:0060420 |
4 |
0.146
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.146
|
|
|
|
mitochondrial membrane organization
|
GO:0007006 |
40 |
0.146
|
|
|
|
positive regulation of stem cell differentiation
|
GO:2000738 |
29 |
0.145
|
Human |
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.144
|
|
|
|
response to cocaine
|
GO:0042220 |
1 |
0.141
|
|
|
|
pallium development
|
GO:0021543 |
10 |
0.140
|
|
|
|
negative regulation of embryonic development
|
GO:0045992 |
4 |
0.139
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.138
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.137
|
|
|
|
regulation of cell matrix adhesion
|
GO:0001952 |
42 |
0.135
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.135
|
|
|
|
positive regulation of mesenchymal cell proliferation
|
GO:0002053 |
2 |
0.135
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.135
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.131
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.131
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.130
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.127
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.126
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.126
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.126
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.125
|
Zebrafish Mouse |
|
|
hindbrain development
|
GO:0030902 |
3 |
0.125
|
|
|
|
mitotic spindle organization
|
GO:0007052 |
27 |
0.124
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.124
|
Zebrafish Mouse Fly |
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.123
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.123
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.122
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.120
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.119
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.118
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.118
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.118
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.118
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.117
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.117
|
Zebrafish Mouse |
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.117
|
|
|
|
negative regulation of muscle organ development
|
GO:0048635 |
12 |
0.116
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.115
|
|
|
|
head development
|
GO:0060322 |
108 |
0.115
|
Zebrafish |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.113
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.112
|
Mouse |
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.110
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.110
|
Human |
|
|
patterning of blood vessels
|
GO:0001569 |
2 |
0.109
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.109
|
Mouse |
|
|
cell growth
|
GO:0016049 |
160 |
0.109
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.109
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.108
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.108
|
Zebrafish |
|
|
immune system development
|
GO:0002520 |
195 |
0.107
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.107
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.107
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.106
|
|
|
|
wnt signaling pathway planar cell polarity pathway
|
GO:0060071 |
5 |
0.106
|
|
|
|
regulation of epithelial to mesenchymal transition
|
GO:0010717 |
37 |
0.105
|
Human |
|
|
hippocampus development
|
GO:0021766 |
1 |
0.104
|
|
|
|
rostrocaudal neural tube patterning
|
GO:0021903 |
1 |
0.103
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.103
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.103
|
|
|
|
common partner smad protein phosphorylation
|
GO:0007182 |
3 |
0.103
|
|
|
|
negative regulation of heart growth
|
GO:0061117 |
2 |
0.103
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.103
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.101
|
Mouse Rat |
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.100
|
Zebrafish Mouse |
|
|
neurological system process
|
GO:0050877 |
163 |
0.100
|
Mouse |
|
|
embryonic hindlimb morphogenesis
|
GO:0035116 |
2 |
0.100
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.099
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.099
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.099
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.099
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.099
|
|
|
|
negative regulation of glial cell proliferation
|
GO:0060253 |
2 |
0.098
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.098
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.098
|
|
|
|
regulation of transforming growth factor beta receptor signaling pathway
|
GO:0017015 |
48 |
0.097
|
Mouse |
|
|
regulation of protein export from nucleus
|
GO:0046825 |
15 |
0.096
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.096
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.095
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.094
|
Zebrafish Mouse |
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.094
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.094
|
Fly |
|
|
bmp signaling pathway
|
GO:0030509 |
49 |
0.093
|
|
|
|
regulation of mitochondrial membrane permeability involved in apoptotic process
|
GO:1902108 |
18 |
0.093
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.093
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.092
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.092
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.092
|
|
|
|
cell surface receptor signaling pathway involved in heart development
|
GO:0061311 |
8 |
0.091
|
|
|
|
regulation of embryonic development
|
GO:0045995 |
20 |
0.091
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.091
|
Mouse |
|
|
negative regulation of cell development
|
GO:0010721 |
48 |
0.090
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.090
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.090
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.089
|
|
|
|
regulation of cell fate specification
|
GO:0042659 |
5 |
0.089
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.089
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.088
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.088
|
Mouse |
|
|
nephron tubule formation
|
GO:0072079 |
1 |
0.088
|
|
|
|
fat cell differentiation
|
GO:0045444 |
32 |
0.087
|
Mouse |
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.087
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.087
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.086
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.085
|
|
|
|
energy reserve metabolic process
|
GO:0006112 |
22 |
0.085
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.084
|
Mouse |
|
|
kidney development
|
GO:0001822 |
53 |
0.084
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.083
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.083
|
|
|
|
gland development
|
GO:0048732 |
48 |
0.082
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.082
|
|
|
|
mitochondrial outer membrane permeabilization
|
GO:0097345 |
15 |
0.082
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.081
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.081
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.080
|
Zebrafish Mouse |
|
|
polysaccharide metabolic process
|
GO:0005976 |
33 |
0.079
|
|
|
|
negative regulation of nfat protein import into nucleus
|
GO:0051534 |
2 |
0.079
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.079
|
|
|
|
cardiac septum development
|
GO:0003279 |
13 |
0.079
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.079
|
|
|
|
skin development
|
GO:0043588 |
76 |
0.078
|
|
|
|
regulation of cardioblast cell fate specification
|
GO:0042686 |
1 |
0.078
|
|
|
|
regulation of calcium mediated signaling
|
GO:0050848 |
17 |
0.078
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.078
|
Mouse |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.078
|
|
|
|
negative regulation of dendrite development
|
GO:2000171 |
5 |
0.077
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.077
|
Human |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.077
|
|
|
|
maintenance of protein location
|
GO:0045185 |
57 |
0.076
|
|
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.076
|
|
|
|
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:2000059 |
3 |
0.076
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.076
|
Fly |
|
|
cerebral cortex radial glia guided migration
|
GO:0021801 |
1 |
0.075
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.074
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.074
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.074
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.074
|
|
|
|
sex differentiation
|
GO:0007548 |
45 |
0.073
|
|
|
|
telencephalon development
|
GO:0021537 |
17 |
0.073
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.073
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.073
|
|
|
|
cell proliferation involved in heart morphogenesis
|
GO:0061323 |
1 |
0.073
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.072
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.072
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.072
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.071
|
Human |
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.071
|
Mouse |
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.071
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.070
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.070
|
Human |
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.070
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.070
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.069
|
|
|
|
endodermal cell differentiation
|
GO:0035987 |
31 |
0.069
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.069
|
|
|
|
negative regulation of glial cell differentiation
|
GO:0045686 |
1 |
0.069
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.069
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.069
|
|
|
|
cardiac muscle cell cardiac muscle cell adhesion
|
GO:0086042 |
1 |
0.069
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.068
|
Zebrafish |
|
|
er nucleus signaling pathway
|
GO:0006984 |
23 |
0.068
|
|
