IMP

Process View

Homo sapiens

9 genes annotated in human

cardiac septum morphogenesis

The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cardiac septum morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cardiac septum morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
JAG1	jagged 1	0.999	Mouse
NOTCH1	notch 1	0.987
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.984
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.974
TAL1	T-cell acute lymphocytic leukemia 1	0.952	Human
NOTCH3	notch 3	0.937	Human
TBX5	T-box 5	0.866	Human Mouse
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.791	Human
BMP2	bone morphogenetic protein 2	0.691
TGFB1	transforming growth factor, beta 1	0.678
FKBP1A	FK506 binding protein 1A, 12kDa	0.676
RUNX1	runt-related transcription factor 1	0.520
GATA2	GATA binding protein 2	0.514	Human
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.476
SETD8	SET domain containing (lysine methyltransferase) 8	0.444
RXRA	retinoid X receptor, alpha	0.383
GATA4	GATA binding protein 4	0.316
SMAD7	SMAD family member 7	0.300	Mouse
MED25	mediator complex subunit 25	0.260
SMAD3	SMAD family member 3	0.235
AXIN1	axin 1	0.234
HNF4A	hepatocyte nuclear factor 4, alpha	0.199
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.173
ACVR1	activin A receptor, type I	0.163
GSK3B	glycogen synthase kinase 3 beta	0.160
MYOD1	myogenic differentiation 1	0.131
CTBP2	C-terminal binding protein 2	0.123
CSNK1E	casein kinase 1, epsilon	0.119
ILK	integrin-linked kinase	0.114
FGF10	fibroblast growth factor 10	0.103
EP300	E1A binding protein p300	0.095
DLL1	delta-like 1 (Drosophila)	0.094
WNT3A	wingless-type MMTV integration site family, member 3A	0.094
MAPK8	mitogen-activated protein kinase 8	0.093
FGF1	fibroblast growth factor 1 (acidic)	0.090
CXXC5	CXXC finger protein 5	0.080
SMAD6	SMAD family member 6	0.078
FSTL1	follistatin-like 1	0.073
TGFBR1	transforming growth factor, beta receptor 1	0.073	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.069
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.063
GDF5	growth differentiation factor 5	0.058
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.057	Human
NOTCH2	notch 2	0.054
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.054	Human
SMAD9	SMAD family member 9	0.053
LRRK2	leucine-rich repeat kinase 2	0.048
CREBBP	CREB binding protein	0.047
TGFB3	transforming growth factor, beta 3	0.045
CTGF	connective tissue growth factor	0.043
SKIL	SKI-like oncogene	0.042
PRKG1	protein kinase, cGMP-dependent, type I	0.042
MSX1	msh homeobox 1	0.041
EPAS1	endothelial PAS domain protein 1	0.041
BMPR1A	bone morphogenetic protein receptor, type IA	0.040	Human
ENG	endoglin	0.038
PAX8	paired box 8	0.038
ZFPM1	zinc finger protein, multitype 1	0.033	Human Mouse
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.033
HOXD12	homeobox D12	0.032
SIRT1	sirtuin 1	0.031
MAML1	mastermind-like 1 (Drosophila)	0.030
MARCKSL1	MARCKS-like 1	0.029
SOX7	SRY (sex determining region Y)-box 7	0.027
JAG2	jagged 2	0.027
WT1	Wilms tumor 1	0.025
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.025
NRP1	neuropilin 1	0.024
SMAD1	SMAD family member 1	0.024
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.022
ZNF512B	zinc finger protein 512B	0.021
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.021
FZD1	frizzled homolog 1 (Drosophila)	0.020	Mouse
BMP4	bone morphogenetic protein 4	0.020
PDGFC	platelet derived growth factor C	0.019
TCF12	transcription factor 12	0.019
POU4F2	POU class 4 homeobox 2	0.018
SOX13	SRY (sex determining region Y)-box 13	0.018
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.017
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.017
HIC1	hypermethylated in cancer 1	0.016
FERMT2	fermitin family member 2	0.016
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.015	Mouse
SOX18	SRY (sex determining region Y)-box 18	0.015
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.015
VEGFA	vascular endothelial growth factor A	0.015
WNT5A	wingless-type MMTV integration site family, member 5A	0.015	Mouse
GATA3	GATA binding protein 3	0.015	Human
FOXF2	forkhead box F2	0.014
FZD7	frizzled homolog 7 (Drosophila)	0.013
ACVR1B	activin A receptor, type IB	0.013	Human
FGF3	fibroblast growth factor 3	0.012
PIAS4	protein inhibitor of activated STAT, 4	0.012
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.012
EFNB2	ephrin-B2	0.012
GATA5	GATA binding protein 5	0.012	Human
TBX2	T-box 2	0.011	Human
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.011
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.011
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.011
NCOA1	nuclear receptor coactivator 1	0.011
THBS1	thrombospondin 1	0.010