Homo sapiens

89 known processes

CD3D

CD3d molecule, delta (CD3-TCR complex)

(Aliases: CD3-DELTA,T3D)

CD3D biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
t cell activation GO:0042110 99 0.652
negative regulation of deoxyribonuclease activity GO:0032076 1 0.604
defense response GO:0006952 315 0.572
leukocyte activation GO:0045321 164 0.519
lymphocyte activation GO:0046649 133 0.405
cell activation GO:0001775 213 0.372
negative regulation of endodeoxyribonuclease activity GO:0032078 1 0.369
immune system development GO:0002520 195 0.354
regulation of calcium mediated signaling GO:0050848 17 0.271
hemopoiesis GO:0030097 180 0.251
second messenger mediated signaling GO:0019932 78 0.244
leukocyte differentiation GO:0002521 98 0.221
hematopoietic or lymphoid organ development GO:0048534 186 0.211
interleukin 1 beta biosynthetic process GO:0050720 2 0.201
immune response GO:0006955 307 0.169
t cell differentiation GO:0030217 29 0.151
response to biotic stimulus GO:0009607 276 0.148
interleukin 1 biosynthetic process GO:0042222 2 0.147
response to external biotic stimulus GO:0043207 261 0.145
positive regulation of apoptotic process GO:0043065 246 0.121
response to other organism GO:0051707 261 0.111
lymphocyte mediated immunity GO:0002449 48 0.108
negative regulation of nuclease activity GO:0032074 2 0.102
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.088
cytokine production GO:0001816 247 0.081
lymphocyte differentiation GO:0030098 35 0.081
purine nucleoside catabolic process GO:0006152 398 0.076
calcium mediated signaling GO:0019722 44 0.073
interleukin 1 beta production GO:0032611 22 0.072
positive regulation of t cell activation GO:0050870 54 0.071
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.070
regulation of cell migration GO:0030334 289 0.069
regulation of cytokine production GO:0001817 232 0.068
apoptotic signaling pathway GO:0097190 268 0.068
immune effector process GO:0002252 159 0.068
glycosyl compound catabolic process GO:1901658 413 0.067
positive regulation of cellular amine metabolic process GO:0033240 7 0.063
positive regulation of immune system process GO:0002684 283 0.063
Human
post embryonic development GO:0009791 2 0.062
purine ribonucleoside catabolic process GO:0046130 398 0.060
cell killing GO:0001906 34 0.055
regulation of nucleotide metabolic process GO:0006140 269 0.055
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.054
negative regulation of catalytic activity GO:0043086 335 0.054
regulation of cell differentiation GO:0045595 393 0.053
t cell differentiation in thymus GO:0033077 4 0.051
Mouse
positive regulation of cell death GO:0010942 263 0.051
negative regulation of hydrolase activity GO:0051346 182 0.049
ion homeostasis GO:0050801 230 0.045
purine nucleoside triphosphate catabolic process GO:0009146 392 0.045
regulation of mononuclear cell proliferation GO:0032944 65 0.045
Human
gtp catabolic process GO:0006184 237 0.044
lymphocyte proliferation GO:0046651 70 0.043
Human
purine nucleotide catabolic process GO:0006195 405 0.043
regulation of immune response GO:0050776 201 0.043
small gtpase mediated signal transduction GO:0007264 78 0.043
lymphocyte apoptotic process GO:0070227 20 0.042
Human
negative regulation of cell proliferation GO:0008285 228 0.041
negative regulation of programmed cell death GO:0043069 321 0.041
negative regulation of cell death GO:0060548 345 0.041
ribonucleoside triphosphate metabolic process GO:0009199 412 0.040
secretion by cell GO:0032940 226 0.040
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.040
positive regulation of immune response GO:0050778 159 0.039
cytoplasmic transport GO:0016482 379 0.039
defense response to other organism GO:0098542 129 0.038
guanosine containing compound catabolic process GO:1901069 239 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.037
cytokine mediated signaling pathway GO:0019221 109 0.037
nucleoside triphosphate metabolic process GO:0009141 422 0.037
ribonucleotide catabolic process GO:0009261 405 0.037
positive regulation of transport GO:0051050 336 0.037
negative regulation of catabolic process GO:0009895 104 0.037
leukocyte apoptotic process GO:0071887 31 0.037
Human
leukocyte mediated immunity GO:0002443 59 0.037
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.036
cellular amino acid metabolic process GO:0006520 116 0.036
regulation of astrocyte chemotaxis GO:2000458 1 0.036
adaptive immune response GO:0002250 49 0.035
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.035
cellular ketone metabolic process GO:0042180 80 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.035
immune response activating signal transduction GO:0002757 90 0.034
regulation of cellular component movement GO:0051270 334 0.034
regulation of cell activation GO:0050865 125 0.034
Human
phagocytosis recognition GO:0006910 3 0.034
cell projection organization GO:0030030 252 0.033
chemokine c c motif ligand 19 signaling pathway GO:0038115 1 0.033
negative regulation of cellular catabolic process GO:0031330 83 0.033
ras protein signal transduction GO:0007265 73 0.033
positive regulation of phosphorylation GO:0042327 394 0.032
innate immune response GO:0045087 178 0.032
positive regulation of developmental process GO:0051094 314 0.032
determination of adult lifespan GO:0008340 2 0.032
organophosphate catabolic process GO:0046434 430 0.032
positive regulation of hydrolase activity GO:0051345 331 0.032
multicellular organismal aging GO:0010259 3 0.031
purine nucleoside triphosphate metabolic process GO:0009144 412 0.031
actin filament based process GO:0030029 224 0.031
mononuclear cell proliferation GO:0032943 71 0.031
Human
ribonucleoside triphosphate catabolic process GO:0009203 391 0.031
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.031
negative regulation of t cell cytokine production GO:0002725 4 0.030
interleukin 1 production GO:0032612 26 0.030
regulation of nucleotide catabolic process GO:0030811 205 0.029
thymic t cell selection GO:0045061 2 0.029
Mouse
purinergic nucleotide receptor signaling pathway GO:0035590 4 0.029
positive regulation of cell proliferation GO:0008284 301 0.029
Human
nucleoside phosphate catabolic process GO:1901292 412 0.028
nucleoside catabolic process GO:0009164 408 0.028
positive regulation of leukocyte activation GO:0002696 80 0.028
Human
amine metabolic process GO:0009308 44 0.028
regulation of t cell proliferation GO:0042129 42 0.027
Human
cellular protein catabolic process GO:0044257 261 0.027
cellular macromolecule catabolic process GO:0044265 380 0.027
metal ion transport GO:0030001 272 0.027
cell type specific apoptotic process GO:0097285 125 0.026
Human
lipid metabolic process GO:0006629 381 0.026
cellular response to cytokine stimulus GO:0071345 181 0.026
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.026
regulation of intracellular transport GO:0032386 195 0.026
cellular divalent inorganic cation homeostasis GO:0072503 128 0.026
chemical homeostasis GO:0048878 306 0.026
response to cytokine GO:0034097 232 0.026
positive regulation of cytokine production GO:0001819 167 0.025
positive regulation of gtp catabolic process GO:0033126 166 0.025
negative regulation of dna metabolic process GO:0051053 57 0.025
activation of immune response GO:0002253 114 0.025
positive regulation of calcium mediated signaling GO:0050850 10 0.025
regulation of cellular ketone metabolic process GO:0010565 50 0.025
regulation of leukocyte proliferation GO:0070663 67 0.024
Human
protein processing GO:0016485 226 0.024
divalent inorganic cation homeostasis GO:0072507 136 0.024
purine ribonucleoside metabolic process GO:0046128 437 0.023
regulation of secretion by cell GO:1903530 177 0.023
positive regulation of cellular component organization GO:0051130 376 0.023
metal ion homeostasis GO:0055065 169 0.022
cell cell recognition GO:0009988 4 0.022
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.022
regulation of lymphocyte activation GO:0051249 103 0.022
Human
positive regulation of programmed cell death GO:0043068 249 0.022
positive regulation of protein phosphorylation GO:0001934 313 0.022
cell morphogenesis GO:0000902 296 0.022
signal transduction by phosphorylation GO:0023014 297 0.022
cellular amine metabolic process GO:0044106 41 0.022
reactive nitrogen species metabolic process GO:2001057 3 0.022
positive regulation of nucleotide metabolic process GO:0045981 230 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.021
vesicle mediated transport GO:0016192 371 0.021
regulation of gtp catabolic process GO:0033124 180 0.021
purine ribonucleotide catabolic process GO:0009154 404 0.021
positive regulation of cellular catabolic process GO:0031331 284 0.021
intracellular protein transport GO:0006886 270 0.021
segmentation GO:0035282 4 0.020
divalent inorganic cation transport GO:0072511 158 0.020
regulation of locomotion GO:0040012 329 0.020
negative regulation of developmental process GO:0051093 247 0.020
response to oxygen containing compound GO:1901700 369 0.020
positive regulation of cell activation GO:0050867 81 0.020
Human
g protein coupled purinergic nucleotide receptor signaling pathway GO:0035589 1 0.020
single organism cellular localization GO:1902580 332 0.020
regulation of response to external stimulus GO:0032101 222 0.020
defense response to virus GO:0051607 71 0.020
positive regulation of cell migration GO:0030335 172 0.019
cation transport GO:0006812 331 0.019
cellular metal ion homeostasis GO:0006875 146 0.019
regulation of neutrophil mediated killing of bacterium GO:0070950 1 0.019
protein autophosphorylation GO:0046777 123 0.019
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.019
neuromuscular junction development GO:0007528 3 0.019
ribonucleoside catabolic process GO:0042454 406 0.019
positive regulation of organelle organization GO:0010638 195 0.019
positive regulation of secretion GO:0051047 116 0.018
guanosine containing compound metabolic process GO:1901068 244 0.018
regulation of defense response GO:0031347 154 0.018
positive thymic t cell selection GO:0045059 1 0.018
Mouse
positive regulation of natural killer cell mediated immunity GO:0002717 12 0.018
positive regulation of catabolic process GO:0009896 310 0.018
regulation of cellular amine metabolic process GO:0033238 11 0.018
oogenesis GO:0048477 2 0.018
regeneration GO:0031099 4 0.018
t cell selection GO:0045058 4 0.018
Mouse
reactive oxygen species biosynthetic process GO:1903409 4 0.018
single organism membrane organization GO:0044802 268 0.018
regulation of establishment of protein localization GO:0070201 242 0.018
regulation of transferase activity GO:0051338 355 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.017
dna catabolic process GO:0006308 49 0.017
purine containing compound catabolic process GO:0072523 411 0.017
positive regulation of innate immune response GO:0045089 79 0.017
antigen receptor mediated signaling pathway GO:0050851 38 0.017
secretion GO:0046903 254 0.017
cellular response to biotic stimulus GO:0071216 71 0.017
female gamete generation GO:0007292 2 0.017
cation homeostasis GO:0055080 189 0.017
regulation of small gtpase mediated signal transduction GO:0051056 156 0.017
regulation of actin cytoskeleton organization GO:0032956 116 0.017
regulation of peptidase activity GO:0052547 180 0.017
sequestering of metal ion GO:0051238 24 0.017
g protein coupled receptor signaling pathway GO:0007186 207 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
neuron projection development GO:0031175 106 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
taxis GO:0042330 157 0.017
interspecies interaction between organisms GO:0044419 156 0.016
endomembrane system organization GO:0010256 196 0.016
regulation of cell projection organization GO:0031344 107 0.016
positive regulation of cellular component movement GO:0051272 181 0.016
cellular cation homeostasis GO:0030003 163 0.016
regulation of dna metabolic process GO:0051052 153 0.016
chemotaxis GO:0006935 157 0.016
response to wounding GO:0009611 168 0.016
sequestering of calcium ion GO:0051208 17 0.016
nucleotide catabolic process GO:0009166 408 0.016
regulation of cellular response to stress GO:0080135 244 0.016
membrane organization GO:0061024 292 0.016
mitotic cell cycle GO:0000278 326 0.016
protein targeting GO:0006605 187 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
cell growth GO:0016049 160 0.016
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.016
protein maturation GO:0051604 233 0.016
regulation of cell cycle GO:0051726 393 0.015
immune response regulating signaling pathway GO:0002764 97 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
regulation of cellular component biogenesis GO:0044087 281 0.015
rho protein signal transduction GO:0007266 26 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
cytosolic calcium ion homeostasis GO:0051480 89 0.015
cellular component morphogenesis GO:0032989 314 0.015
negative regulation of cellular protein metabolic process GO:0032269 353 0.015
positive regulation of mapk cascade GO:0043410 190 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
cell adhesion GO:0007155 325 0.015
positive regulation of lymphocyte activation GO:0051251 73 0.015
Human
positive regulation of leukocyte proliferation GO:0070665 48 0.014
Human
negative regulation of cellular component organization GO:0051129 235 0.014
cellular calcium ion homeostasis GO:0006874 117 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
regulation of binding GO:0051098 111 0.014
cellular response to lipid GO:0071396 127 0.014
regulation of actin filament based process GO:0032970 141 0.014
positive regulation of cell differentiation GO:0045597 211 0.014
nervous system development GO:0007399 293 0.014
positive regulation of defense response GO:0031349 87 0.014
intrinsic apoptotic signaling pathway GO:0097193 127 0.014
negative regulation of cell motility GO:2000146 104 0.014
leukocyte chemotaxis GO:0030595 76 0.014
vasculature development GO:0001944 181 0.014
regulation of homeostatic process GO:0032844 121 0.014
negative regulation of phosphorus metabolic process GO:0010563 267 0.014
mitotic cell cycle process GO:1903047 286 0.013
leukocyte proliferation GO:0070661 74 0.013
Human
blood vessel morphogenesis GO:0048514 162 0.013
response to fungus GO:0009620 4 0.013
t cell proliferation GO:0042098 45 0.013
Human
negative regulation of intracellular signal transduction GO:1902532 183 0.013
stress activated mapk cascade GO:0051403 93 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
regulation of mapk cascade GO:0043408 262 0.013
regulation of kinase activity GO:0043549 314 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
regulation of leukocyte activation GO:0002694 115 0.013
Human
negative regulation of protein metabolic process GO:0051248 391 0.013
regulation of cytoplasmic transport GO:1903649 149 0.013
negative regulation of proteolysis GO:0045861 132 0.013
positive regulation of cell cycle process GO:0090068 106 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
positive regulation of alpha beta t cell differentiation GO:0046638 4 0.013
positive regulation of t cell receptor signaling pathway GO:0050862 2 0.013
growth GO:0040007 202 0.013
actin cytoskeleton organization GO:0030036 207 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.013
regulation of epithelial cell proliferation GO:0050678 113 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
regulation of cell division GO:0051302 116 0.013
cellular homeostasis GO:0019725 196 0.013
regulation of gtpase activity GO:0043087 180 0.012
positive regulation of lymphocyte mediated immunity GO:0002708 23 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
regulation of nuclease activity GO:0032069 11 0.012
protein catabolic process GO:0030163 325 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
system process GO:0003008 349 0.012
regulation of dna binding GO:0051101 37 0.012
regulation of protein kinase activity GO:0045859 289 0.012
memory GO:0007613 3 0.012
negative regulation of smoothened signaling pathway GO:0045879 3 0.012
mature dendritic cell differentiation GO:0097029 2 0.012
regulation of metal ion transport GO:0010959 120 0.012
epithelium migration GO:0090132 119 0.012
microtubule based process GO:0007017 210 0.012
chemokine c c motif ligand 21 signaling pathway GO:0038116 1 0.012
positive regulation of cell cycle GO:0045787 140 0.012
regulation of secretion GO:0051046 194 0.012
biological adhesion GO:0022610 331 0.012
positive regulation of lymphocyte proliferation GO:0050671 46 0.012
Human
mapk cascade GO:0000165 288 0.012
regulation of protein complex assembly GO:0043254 147 0.012
cellular macromolecular complex assembly GO:0034622 324 0.012
cell projection assembly GO:0030031 126 0.012
regulation of cell motility GO:2000145 299 0.012
regulation of ras protein signal transduction GO:0046578 155 0.012
calcium ion transport GO:0006816 147 0.012
generation of neurons GO:0048699 152 0.012
regulation of ion homeostasis GO:2000021 73 0.011
response to virus GO:0009615 126 0.011
lipid biosynthetic process GO:0008610 177 0.011
regulation of vasculature development GO:1901342 97 0.011
organ morphogenesis GO:0009887 147 0.011
gtp metabolic process GO:0046039 239 0.011
regulation of cell cycle process GO:0010564 266 0.011
protein localization to organelle GO:0033365 280 0.011
neurogenesis GO:0022008 169 0.011
cell division GO:0051301 168 0.011
negative regulation of immune system process GO:0002683 136 0.011
regulation of ras gtpase activity GO:0032318 128 0.011
regulation of protein maturation GO:1903317 150 0.011
positive regulation of protein transport GO:0051222 135 0.011
anatomical structure homeostasis GO:0060249 100 0.011
cellular ion homeostasis GO:0006873 168 0.011
positive regulation of cell motility GO:2000147 177 0.011
regulation of growth GO:0040008 165 0.011
small molecule biosynthetic process GO:0044283 157 0.011
regulation of rho protein signal transduction GO:0035023 79 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
dendritic cell antigen processing and presentation GO:0002468 1 0.011
locomotory behavior GO:0007626 1 0.011
organelle assembly GO:0070925 176 0.011
mating GO:0007618 1 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
regulation of cell morphogenesis GO:0022604 153 0.011
cellular lipid metabolic process GO:0044255 303 0.010
membrane hyperpolarization GO:0060081 1 0.010
wound healing GO:0042060 115 0.010
cellular protein complex assembly GO:0043623 188 0.010
skeletal system development GO:0001501 79 0.010
oocyte differentiation GO:0009994 2 0.010
cytosolic calcium ion transport GO:0060401 48 0.010
regulation of proteolysis GO:0030162 293 0.010
positive regulation of interferon gamma production GO:0032729 26 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
protein import GO:0017038 130 0.010
lymphocyte costimulation GO:0031294 7 0.010
positive regulation of natural killer cell mediated cytotoxicity GO:0045954 11 0.010
regulation of leukocyte chemotaxis GO:0002688 46 0.010
cell cycle phase transition GO:0044770 173 0.010
cell development GO:0048468 328 0.010
glycoprotein metabolic process GO:0009100 110 0.010
negative regulation of growth GO:0045926 97 0.010
regulation of t cell activation GO:0050863 77 0.010
Human
stress activated protein kinase signaling cascade GO:0031098 94 0.010
motor neuron axon guidance GO:0008045 2 0.010
tripartite regional subdivision GO:0007351 2 0.010
regulation of erk1 and erk2 cascade GO:0070372 99 0.010
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.010
positive regulation of mononuclear cell proliferation GO:0032946 47 0.010
Human

CD3D disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.095
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
hematopoietic system disease DOID:74 100 0.011