Homo sapiens

0 known processes

HLA-DRB5

major histocompatibility complex, class II, DR beta 5

(Aliases: FLJ76359,HLA-DRB)

HLA-DRB5 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
dendritic cell antigen processing and presentation GO:0002468 1 0.996
regulation of interleukin 10 secretion GO:2001179 4 0.940
Human
detection of external biotic stimulus GO:0098581 19 0.937
Human
polysaccharide assembly with mhc class ii protein complex GO:0002506 2 0.920
Human
peptide antigen assembly with mhc class ii protein complex GO:0002503 4 0.864
Human
negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002581 3 0.860
negative regulation of immune response GO:0050777 40 0.854
Human
peptide antigen assembly with mhc protein complex GO:0002501 4 0.851
Human
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 11 0.809
Human
antigen processing and presentation of peptide antigen GO:0048002 18 0.801
Human
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.800
negative regulation of antigen processing and presentation GO:0002578 5 0.796
lymphocyte mediated immunity GO:0002449 48 0.744
Human
cytokine production GO:0001816 247 0.740
Human
mhc class ii protein complex assembly GO:0002399 4 0.734
Human
negative regulation of cell proliferation GO:0008285 228 0.655
Human
regulation of cytokine production GO:0001817 232 0.621
Human
antigen processing and presentation GO:0019882 33 0.621
Human
interleukin 10 production GO:0032613 17 0.607
Human
regulation of interferon gamma production GO:0032649 36 0.598
Human
positive regulation of hormone secretion GO:0046887 25 0.577
Human
regulation of t cell proliferation GO:0042129 42 0.572
Human
t helper 1 type immune response GO:0042088 8 0.544
Human
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 1 0.531
positive regulation of leukocyte activation GO:0002696 80 0.526
inflammatory response to antigenic stimulus GO:0002437 4 0.524
Human
regulation of lymphocyte proliferation GO:0050670 64 0.517
Human
leukocyte mediated immunity GO:0002443 59 0.486
Human
lymphocyte proliferation GO:0046651 70 0.456
Human
response to bacterium GO:0009617 144 0.451
Human
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 12 0.440
Human
t cell selection GO:0045058 4 0.434
peptide transport GO:0015833 74 0.433
Human
hormone secretion GO:0046879 65 0.433
Human
defense response GO:0006952 315 0.418
Human
innate immune response GO:0045087 178 0.413
protein carbohydrate complex subunit organization GO:0071823 2 0.408
Human
positive regulation of antigen processing and presentation GO:0002579 1 0.406
regulation of defense response GO:0031347 154 0.404
Human
negative regulation of t cell proliferation GO:0042130 8 0.404
Human
protein oligomerization GO:0051259 173 0.399
Human
regulation of protein transport GO:0051223 213 0.393
Human
regulation of t cell activation GO:0050863 77 0.388
Human
regulation of peptide hormone secretion GO:0090276 41 0.379
Human
positive regulation of immune response GO:0050778 159 0.374
immune response GO:0006955 307 0.373
Human
positive regulation of lymphocyte activation GO:0051251 73 0.359
peptide secretion GO:0002790 51 0.343
Human
positive regulation of lymphocyte proliferation GO:0050671 46 0.340
cellular amino acid metabolic process GO:0006520 116 0.340
cellular homeostasis GO:0019725 196 0.328
Human
cell activation GO:0001775 213 0.326
Human
signal release GO:0023061 70 0.325
Human
protein secretion GO:0009306 98 0.315
Human
regulation of leukocyte proliferation GO:0070663 67 0.312
Human
negative regulation of interferon gamma production GO:0032689 9 0.300
Human
response to biotic stimulus GO:0009607 276 0.293
Human
regulation of antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002580 4 0.292
regulation of response to wounding GO:1903034 101 0.292
Human
positive regulation of t cell activation GO:0050870 54 0.292
positive regulation of cell activation GO:0050867 81 0.288
cellular protein complex assembly GO:0043623 188 0.284
Human
cellular response to oxygen containing compound GO:1901701 276 0.282
Human
regulation of lymphocyte activation GO:0051249 103 0.280
Human
leukocyte proliferation GO:0070661 74 0.279
Human
regulation of cell activation GO:0050865 125 0.277
Human
leukocyte activation GO:0045321 164 0.276
Human
positive regulation of secretion GO:0051047 116 0.272
Human
de novo protein folding GO:0006458 2 0.268
glucose homeostasis GO:0042593 31 0.265
Human
lymphocyte activation GO:0046649 133 0.265
Human
positive regulation of insulin secretion GO:0032024 10 0.261
Human
cellular response to interferon gamma GO:0071346 24 0.258
cellular chemical homeostasis GO:0055082 180 0.256
Human
regulation of protein secretion GO:0050708 86 0.256
Human
t cell proliferation GO:0042098 45 0.247
Human
interferon gamma production GO:0032609 39 0.245
Human
negative regulation of defense response GO:0031348 47 0.244
Human
cytokine secretion GO:0050663 64 0.234
Human
humoral immune response GO:0006959 49 0.233
Human
regulation of leukocyte activation GO:0002694 115 0.232
Human
detection of other organism GO:0098543 13 0.231
Human
secretion by cell GO:0032940 226 0.225
Human
positive regulation of adaptive immune response GO:0002821 21 0.225
positive regulation of immune system process GO:0002684 283 0.213
t cell activation GO:0042110 99 0.207
Human
negative regulation of response to external stimulus GO:0032102 83 0.207
Human
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 4 0.203
hormone transport GO:0009914 68 0.203
Human
positive regulation of lymphocyte differentiation GO:0045621 13 0.202
positive regulation of cellular amine metabolic process GO:0033240 7 0.201
cellular response to ammonium ion GO:0071242 4 0.201
response to oxygen containing compound GO:1901700 369 0.184
Human
negative regulation of cell differentiation GO:0045596 171 0.180
protein carbohydrate complex assembly GO:0065006 2 0.179
Human
nitrogen compound transport GO:0071705 191 0.178
Human
cellular macromolecular complex assembly GO:0034622 324 0.173
Human
regulation of immune response GO:0050776 201 0.171
Human
response to fungus GO:0009620 4 0.166
response to other organism GO:0051707 261 0.166
Human
mononuclear cell proliferation GO:0032943 71 0.162
Human
cellular amine metabolic process GO:0044106 41 0.148
regulation of establishment of protein localization GO:0070201 242 0.146
Human
peptide hormone secretion GO:0030072 50 0.144
Human
secretion GO:0046903 254 0.144
Human
regulation of cell migration GO:0030334 289 0.143
interleukin 10 secretion GO:0072608 5 0.142
Human
antigen processing and presentation of exogenous peptide antigen GO:0002478 4 0.140
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002822 29 0.140
system process GO:0003008 349 0.134
positive regulation of peptide secretion GO:0002793 15 0.131
Human
mhc protein complex assembly GO:0002396 4 0.129
Human
humoral immune response mediated by circulating immunoglobulin GO:0002455 5 0.128
Human
positive regulation of protein kinase activity GO:0045860 190 0.128
unsaturated fatty acid metabolic process GO:0033559 37 0.125
regulation of secretion by cell GO:1903530 177 0.123
Human
interleukin 4 production GO:0032633 7 0.123
Human
positive regulation of peptide hormone secretion GO:0090277 15 0.122
Human
hematopoietic or lymphoid organ development GO:0048534 186 0.118
negative regulation of immune system process GO:0002683 136 0.115
Human
regulation of interleukin 10 production GO:0032653 16 0.112
Human
response to external biotic stimulus GO:0043207 261 0.110
Human
cellular glucose homeostasis GO:0001678 11 0.108
Human
regulation of hormone levels GO:0010817 125 0.102
Human
cellular response to glucose stimulus GO:0071333 10 0.101
Human
response to hexose GO:0009746 20 0.101
Human
hemopoiesis GO:0030097 180 0.096
immune system development GO:0002520 195 0.092
positive regulation of secretion by cell GO:1903532 108 0.092
Human
positive regulation of cell proliferation GO:0008284 301 0.091
positive regulation of transport GO:0051050 336 0.089
Human
regulation of interleukin 4 production GO:0032673 7 0.089
Human
negative regulation of inflammatory response GO:0050728 22 0.088
Human
negative regulation of antigen processing and presentation of peptide antigen GO:0002584 3 0.087
amide transport GO:0042886 76 0.084
Human
chemical homeostasis GO:0048878 306 0.082
Human
detection of biotic stimulus GO:0009595 21 0.081
Human
positive regulation of homeostatic process GO:0032846 47 0.080
Human
negative regulation of t cell activation GO:0050868 18 0.079
Human
neurological system process GO:0050877 163 0.078
detection of bacterium GO:0016045 13 0.078
Human
immunoglobulin mediated immune response GO:0016064 10 0.077
Human
regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002586 3 0.075
production of molecular mediator of immune response GO:0002440 37 0.075
Human
response to glucose GO:0009749 19 0.074
Human
regulation of cellular ketone metabolic process GO:0010565 50 0.074
negative regulation of antigen processing and presentation of peptide antigen via mhc class ii GO:0002587 2 0.072
cell cell signaling GO:0007267 155 0.070
Human
negative regulation of lymphocyte activation GO:0051250 24 0.070
Human
response to cytokine GO:0034097 232 0.070
amine metabolic process GO:0009308 44 0.069
regulation of protein localization GO:0032880 296 0.067
Human
positive regulation of t cell differentiation GO:0045582 11 0.067
response to interferon gamma GO:0034341 39 0.066
regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001188 2 0.066
dendritic cell differentiation GO:0097028 13 0.062
regulation of peptide secretion GO:0002791 42 0.062
Human
positive regulation of mononuclear cell proliferation GO:0032946 47 0.061
biological adhesion GO:0022610 331 0.061
cellular response to monosaccharide stimulus GO:0071326 10 0.060
Human
regulation of insulin secretion GO:0050796 33 0.058
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.056
regulation of secretion GO:0051046 194 0.056
Human
positive regulation of macrophage chemotaxis GO:0010759 3 0.056
cell projection organization GO:0030030 252 0.055
response to carbohydrate GO:0009743 21 0.054
Human
negative regulation of leukocyte proliferation GO:0070664 16 0.053
Human
regulation of mononuclear cell proliferation GO:0032944 65 0.053
Human
positive regulation of t cell proliferation GO:0042102 33 0.053
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 3 0.052
Human
regulation of immune effector process GO:0002697 91 0.052
negative regulation of dendritic cell differentiation GO:2001199 2 0.052
detection of stimulus GO:0051606 85 0.051
Human
regulation of inflammatory response to antigenic stimulus GO:0002861 2 0.050
Human
protein tetramerization GO:0051262 47 0.049
Human
cation transport GO:0006812 331 0.049
positive thymic t cell selection GO:0045059 1 0.049
post embryonic development GO:0009791 2 0.046
positive regulation of developmental process GO:0051094 314 0.046
regulation of adaptive immune response GO:0002819 33 0.045
response to wounding GO:0009611 168 0.044
Human
positive regulation of cell migration GO:0030335 172 0.044
regulation of cellular amine metabolic process GO:0033238 11 0.043
negative regulation of multicellular organismal process GO:0051241 317 0.041
Human
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002824 19 0.041
nucleoside phosphate catabolic process GO:1901292 412 0.041
insulin secretion GO:0030073 39 0.040
Human
b cell homeostasis GO:0001782 1 0.040
cellular response to cytokine stimulus GO:0071345 181 0.039
mapk cascade GO:0000165 288 0.039
cellular response to hexose stimulus GO:0071331 10 0.038
Human
signal transduction by phosphorylation GO:0023014 297 0.038
protein maturation GO:0051604 233 0.038
negative regulation of catalytic activity GO:0043086 335 0.038
ribonucleoside catabolic process GO:0042454 406 0.036
regulation of leukocyte mediated immunity GO:0002703 38 0.036
regulation of cellular amino acid metabolic process GO:0006521 6 0.035
immunoglobulin production GO:0002377 12 0.034
Human
positive regulation of cytokine production GO:0001819 167 0.034
negative regulation of mononuclear cell proliferation GO:0032945 15 0.034
Human
regulation of cellular response to stress GO:0080135 244 0.034
positive regulation of protein transport GO:0051222 135 0.033
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.033
Human
insulin secretion involved in cellular response to glucose stimulus GO:0035773 7 0.033
Human
cellular response to molecule of bacterial origin GO:0071219 62 0.032
taxis GO:0042330 157 0.032
small gtpase mediated signal transduction GO:0007264 78 0.032
intracellular protein transport GO:0006886 270 0.031
regulation of inflammatory response GO:0050727 46 0.031
Human
negative regulation of inflammatory response to antigenic stimulus GO:0002862 2 0.031
Human
cellular ketone metabolic process GO:0042180 80 0.031
nucleoside catabolic process GO:0009164 408 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.030
regulation of neutrophil migration GO:1902622 10 0.030
cellular response to endogenous stimulus GO:0071495 336 0.030
lipid metabolic process GO:0006629 381 0.030
positive regulation of t helper 1 type immune response GO:0002827 4 0.030
negative regulation of programmed cell death GO:0043069 321 0.030
regulation of kinase activity GO:0043549 314 0.030
regulation of transferase activity GO:0051338 355 0.028
immune effector process GO:0002252 159 0.028
Human
fatty acid derivative biosynthetic process GO:1901570 18 0.028
regulation of cytokine secretion GO:0050707 57 0.027
Human
cytokine mediated signaling pathway GO:0019221 109 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
response to organonitrogen compound GO:0010243 156 0.026
regulation of chemotaxis GO:0050920 74 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
positive regulation of kinase activity GO:0033674 204 0.026
cd4 positive alpha beta t cell proliferation GO:0035739 2 0.026
multicellular organismal aging GO:0010259 3 0.026
t cell tolerance induction GO:0002517 4 0.026
negative regulation of hydrolase activity GO:0051346 182 0.026
purine containing compound catabolic process GO:0072523 411 0.025
sensory perception of pain GO:0019233 4 0.025
regulation of cellular component movement GO:0051270 334 0.025
cation homeostasis GO:0055080 189 0.025
cellular lipid metabolic process GO:0044255 303 0.024
organophosphate catabolic process GO:0046434 430 0.024
vesicle mediated transport GO:0016192 371 0.024
cell adhesion GO:0007155 325 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
purine ribonucleoside catabolic process GO:0046130 398 0.024
endocytosis GO:0006897 159 0.023
negative regulation of leukocyte differentiation GO:1902106 24 0.023
regulation of leukocyte chemotaxis GO:0002688 46 0.023
positive regulation of jnk cascade GO:0046330 52 0.023
monocarboxylic acid biosynthetic process GO:0072330 67 0.023
ribonucleoside triphosphate metabolic process GO:0009199 412 0.023
transmembrane transport GO:0055085 399 0.022
positive regulation of cell death GO:0010942 263 0.022
purine nucleoside triphosphate catabolic process GO:0009146 392 0.022
metal ion transport GO:0030001 272 0.022
regulation of cd4 positive alpha beta t cell proliferation GO:2000561 2 0.022
negative regulation of t cell apoptotic process GO:0070233 4 0.022
positive t cell selection GO:0043368 2 0.022
regulation of response to external stimulus GO:0032101 222 0.022
Human
cellular cation homeostasis GO:0030003 163 0.022
detection of chemical stimulus GO:0009593 55 0.021
regulation of leukocyte differentiation GO:1902105 61 0.021
regulation of cytoskeleton organization GO:0051493 177 0.021
oogenesis GO:0048477 2 0.021
b cell mediated immunity GO:0019724 10 0.021
Human
regulation of cell motility GO:2000145 299 0.021
actin filament based process GO:0030029 224 0.021
posttranscriptional regulation of gene expression GO:0010608 213 0.021
positive regulation of cellular component organization GO:0051130 376 0.021
i kappab kinase nf kappab signaling GO:0007249 166 0.021
cellular response to glucocorticoid stimulus GO:0071385 4 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.021
ras protein signal transduction GO:0007265 73 0.020
tissue homeostasis GO:0001894 63 0.020
granzyme a production GO:0035746 1 0.020
ribonucleotide catabolic process GO:0009261 405 0.020
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.020
carbohydrate homeostasis GO:0033500 31 0.020
Human
regulation of locomotion GO:0040012 329 0.020
positive regulation of transferase activity GO:0051347 227 0.020
antigen processing and presentation of exogenous antigen GO:0019884 4 0.020
regulation of complement activation lectin pathway GO:0001868 2 0.020
negative regulation of intracellular signal transduction GO:1902532 183 0.020
purine nucleoside catabolic process GO:0006152 398 0.019
negative regulation of cell death GO:0060548 345 0.019
regulation of protein kinase activity GO:0045859 289 0.019
cellular response to nitrogen compound GO:1901699 144 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
divalent metal ion transport GO:0070838 152 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
positive regulation of ion transport GO:0043270 87 0.019
regulation of regulatory t cell differentiation GO:0045589 4 0.019
determination of adult lifespan GO:0008340 2 0.019
negative regulation of t cell cytokine production GO:0002725 4 0.019
rho protein signal transduction GO:0007266 26 0.019
cell type specific apoptotic process GO:0097285 125 0.019
adaptive immune response GO:0002250 49 0.019
Human
cellular ion homeostasis GO:0006873 168 0.019
establishment of t cell polarity GO:0001768 2 0.018
jnk cascade GO:0007254 80 0.018
response to virus GO:0009615 126 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
response to hormone GO:0009725 175 0.018
regulation of chemokine mediated signaling pathway GO:0070099 6 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
regulation of mapk cascade GO:0043408 262 0.018
regulation of production of molecular mediator of immune response GO:0002700 25 0.018
positive regulation of locomotion GO:0040017 186 0.018
regulation of sensory perception of pain GO:0051930 3 0.018
regulation of innate immune response GO:0045088 97 0.017
response to nitrogen compound GO:1901698 184 0.017
eosinophil activation GO:0043307 3 0.017
regulation of actin filament based process GO:0032970 141 0.017
eosinophil degranulation GO:0043308 2 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.017
negative regulation of peptidase activity GO:0010466 91 0.017
regulation of proteolysis GO:0030162 293 0.017
g protein coupled receptor signaling pathway GO:0007186 207 0.017
nucleotide catabolic process GO:0009166 408 0.017
negative regulation of cellular protein metabolic process GO:0032269 353 0.017
negative regulation of cell activation GO:0050866 33 0.017
Human
regulation of cellular component biogenesis GO:0044087 281 0.017
apoptotic signaling pathway GO:0097190 268 0.017
regulation of gtpase activity GO:0043087 180 0.017
positive regulation of innate immune response GO:0045089 79 0.017
positive regulation of cellular component biogenesis GO:0044089 158 0.017
negative regulation of cellular component organization GO:0051129 235 0.017
guanosine containing compound metabolic process GO:1901068 244 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
negative regulation of phosphorus metabolic process GO:0010563 267 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
response to organic cyclic compound GO:0014070 204 0.016
ion homeostasis GO:0050801 230 0.016
cellular response to lipid GO:0071396 127 0.016
regulation of ras protein signal transduction GO:0046578 155 0.016
positive regulation of behavior GO:0048520 60 0.016
negative regulation of leukocyte activation GO:0002695 26 0.016
Human
peptidyl tyrosine phosphorylation GO:0018108 170 0.016
regulation of cell differentiation GO:0045595 393 0.016
chaperone mediated protein folding GO:0061077 13 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
nucleoside triphosphate metabolic process GO:0009141 422 0.016
interspecies interaction between organisms GO:0044419 156 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
regulation of vasculature development GO:1901342 97 0.015
negative regulation of apoptotic process GO:0043066 316 0.015
segmentation GO:0035282 4 0.015
regulation of cell development GO:0060284 161 0.015
regulation of macrophage chemotaxis GO:0010758 4 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
regulation of tolerance induction GO:0002643 4 0.015
sensory perception GO:0007600 103 0.015
female gamete generation GO:0007292 2 0.015
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.015
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.015
regulation of c c chemokine binding GO:2001263 1 0.015
negative regulation of c c chemokine binding GO:2001264 1 0.015
regulation of hormone secretion GO:0046883 57 0.015
Human
regulation of dendritic cell differentiation GO:2001198 3 0.015
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.015
mitotic cell cycle process GO:1903047 286 0.015
positive regulation of cell motility GO:2000147 177 0.015
carbohydrate metabolic process GO:0005975 207 0.015
maintenance of location GO:0051235 112 0.015
positive regulation of intracellular transport GO:0032388 104 0.014
positive regulation of protein phosphorylation GO:0001934 313 0.014
cytoplasmic transport GO:0016482 379 0.014
positive regulation of organelle organization GO:0010638 195 0.014
regulation of multi organism process GO:0043900 157 0.014
glycosyl compound catabolic process GO:1901658 413 0.014
protein ubiquitination GO:0016567 314 0.014
circulatory system development GO:0072359 262 0.014
response to inorganic substance GO:0010035 127 0.014
positive regulation of mapk cascade GO:0043410 190 0.014
response to corticosteroid GO:0031960 15 0.014
oocyte differentiation GO:0009994 2 0.014
nuclear transport GO:0051169 179 0.014
stress activated mapk cascade GO:0051403 93 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
cell development GO:0048468 328 0.014
response to dexamethasone GO:0071548 1 0.013
de novo posttranslational protein folding GO:0051084 2 0.013
positive regulation of interferon gamma production GO:0032729 26 0.013
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.013
negative regulation of cd4 positive alpha beta t cell proliferation GO:2000562 1 0.013
inositol lipid mediated signaling GO:0048017 55 0.013
memory GO:0007613 3 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
multi organism cellular process GO:0044764 156 0.013
leukocyte migration GO:0050900 107 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.013
sensory perception of taste GO:0050909 36 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
regulation of synaptic plasticity GO:0048167 3 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
negative regulation of protein metabolic process GO:0051248 391 0.013
nervous system development GO:0007399 293 0.013
myeloid cell differentiation GO:0030099 117 0.013
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.013
response to abiotic stimulus GO:0009628 336 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
positive regulation of protein secretion GO:0050714 60 0.013
positive regulation of cellular component movement GO:0051272 181 0.013
organelle assembly GO:0070925 176 0.012
neuromuscular junction development GO:0007528 3 0.012
positive regulation of cytoskeleton organization GO:0051495 83 0.012
mitotic cell cycle GO:0000278 326 0.012
fatty acid derivative metabolic process GO:1901568 35 0.012
salivary gland morphogenesis GO:0007435 4 0.012
actin filament organization GO:0007015 128 0.012
regulation of homeostatic process GO:0032844 121 0.012
Human
negative regulation of cytokine production involved in immune response GO:0002719 13 0.012
negative regulation of b cell apoptotic process GO:0002903 4 0.012
regulation of t cell tolerance induction GO:0002664 4 0.012
positive regulation of apoptotic process GO:0043065 246 0.012
myeloid dendritic cell activation GO:0001773 4 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
cell morphogenesis GO:0000902 296 0.012
positive regulation of hydrolase activity GO:0051345 331 0.012
protein polymerization GO:0051258 71 0.012
anatomical structure homeostasis GO:0060249 100 0.012
regulation of ras gtpase activity GO:0032318 128 0.012
regulation of intracellular transport GO:0032386 195 0.012
negative regulation of chemotaxis GO:0050922 13 0.012
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.012
regulation of cell cycle GO:0051726 393 0.012
cellular response to oxidative stress GO:0034599 85 0.012
generation of neurons GO:0048699 152 0.012
inorganic anion transmembrane transport GO:0098661 47 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.012
anion transport GO:0006820 161 0.012
positive regulation of acute inflammatory response GO:0002675 2 0.012
peptidyl tyrosine modification GO:0018212 170 0.012
cellular metal ion homeostasis GO:0006875 146 0.012
t cell mediated immunity GO:0002456 25 0.012
regulation of protein binding GO:0043393 66 0.012
negative regulation of homeostatic process GO:0032845 59 0.012
leukocyte differentiation GO:0002521 98 0.012
erk1 and erk2 cascade GO:0070371 104 0.012
cytokine production involved in immune response GO:0002367 27 0.012
regulation of ion transmembrane transport GO:0034765 132 0.012
spermatid differentiation GO:0048515 4 0.011
glial cell migration GO:0008347 4 0.011
single organism carbohydrate metabolic process GO:0044723 193 0.011
single organism cell adhesion GO:0098602 179 0.011
azole transport GO:0045117 4 0.011
cardiovascular system development GO:0072358 262 0.011
cellular protein catabolic process GO:0044257 261 0.011
blastoderm segmentation GO:0007350 2 0.011
rhythmic behavior GO:0007622 2 0.011
negative regulation of cell cycle GO:0045786 193 0.011
negative regulation of response to wounding GO:1903035 47 0.011
Human
negative regulation of multi organism process GO:0043901 92 0.011
positive regulation of response to external stimulus GO:0032103 88 0.011
gtp catabolic process GO:0006184 237 0.011
regulation of protein stability GO:0031647 87 0.011
cell cycle phase transition GO:0044770 173 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
response to salt stress GO:0009651 3 0.011
positive regulation of leukocyte proliferation GO:0070665 48 0.011
defense response to virus GO:0051607 71 0.011
activation of immune response GO:0002253 114 0.011
calcium ion import GO:0070509 23 0.011
antigen processing and presentation via mhc class ib GO:0002475 3 0.011
regulation of rho protein signal transduction GO:0035023 79 0.011
tissue regeneration GO:0042246 3 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
response to molecule of bacterial origin GO:0002237 82 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
carbohydrate derivative biosynthetic process GO:1901137 207 0.011
dephosphorylation GO:0016311 209 0.011

HLA-DRB5 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.781
Human
hypersensitivity reaction disease DOID:0060056 25 0.781
Human
musculoskeletal system disease DOID:17 223 0.593
Human
bone disease DOID:0080001 88 0.372
Human
connective tissue disease DOID:65 109 0.372
Human
central nervous system disease DOID:331 186 0.301
Human
nervous system disease DOID:863 431 0.301
Human
neurodegenerative disease DOID:1289 102 0.288
Human
hypersensitivity reaction type iv disease DOID:2916 6 0.020
Human
brain disease DOID:936 73 0.019
Human
disease of metabolism DOID:0014667 295 0.017
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
disease by infectious agent DOID:0050117 34 0.013
disease of cellular proliferation DOID:14566 174 0.013
bone inflammation disease DOID:3342 10 0.012
Human
rheumatoid arthritis DOID:7148 8 0.012
Human
arthritis DOID:848 8 0.012
Human
cancer DOID:162 167 0.011
organ system cancer DOID:0050686 164 0.011