|
|
regulation of interferon beta biosynthetic process
|
GO:0045357 |
4 |
1.000
|
|
|
|
positive regulation of interferon beta production
|
GO:0032728 |
17 |
0.998
|
Human |
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.988
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.964
|
|
|
|
serine phosphorylation of stat protein
|
GO:0042501 |
4 |
0.926
|
Human |
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.920
|
|
|
|
positive regulation of interferon beta biosynthetic process
|
GO:0045359 |
4 |
0.879
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.871
|
|
|
|
positive regulation of interferon alpha production
|
GO:0032727 |
11 |
0.852
|
Human |
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.849
|
Human |
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.842
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.790
|
|
|
|
positive regulation of type i interferon production
|
GO:0032481 |
20 |
0.790
|
Human |
|
|
innate immune response
|
GO:0045087 |
178 |
0.766
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.763
|
Fly |
|
|
cell activation
|
GO:0001775 |
213 |
0.748
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.745
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.731
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.712
|
|
|
|
programmed necrotic cell death
|
GO:0097300 |
18 |
0.703
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.685
|
Human |
|
|
regulation of immune effector process
|
GO:0002697 |
91 |
0.680
|
|
|
|
regulation of type i interferon mediated signaling pathway
|
GO:0060338 |
9 |
0.673
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.657
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.645
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.633
|
Human |
|
|
response to lipid
|
GO:0033993 |
206 |
0.571
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.569
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.558
|
Human |
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.536
|
Human |
|
|
interferon beta biosynthetic process
|
GO:0045350 |
4 |
0.527
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.517
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.491
|
|
|
|
jak stat cascade
|
GO:0007259 |
46 |
0.485
|
|
|
|
interferon beta production
|
GO:0032608 |
23 |
0.466
|
Human |
|
|
muscle contraction
|
GO:0006936 |
73 |
0.437
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.427
|
Fly |
|
|
regulation of defense response to virus by host
|
GO:0050691 |
22 |
0.422
|
|
|
|
muscle system process
|
GO:0003012 |
81 |
0.421
|
|
|
|
interferon alpha production
|
GO:0032607 |
11 |
0.416
|
Human |
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.414
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.409
|
Fly |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.391
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.388
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.384
|
Human |
|
|
cellular response to tumor necrosis factor
|
GO:0071356 |
63 |
0.380
|
Human |
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.373
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.369
|
|
|
|
adaptive immune response
|
GO:0002250 |
49 |
0.367
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.361
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.357
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.353
|
Fly |
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.351
|
Fly |
|
|
regulation of defense response to virus
|
GO:0050688 |
33 |
0.347
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.336
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.333
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.328
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.325
|
Human |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.322
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.321
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.319
|
|
|
|
striated muscle contraction
|
GO:0006941 |
52 |
0.317
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.315
|
|
|
|
mononuclear cell proliferation
|
GO:0032943 |
71 |
0.289
|
|
|
|
type i interferon production
|
GO:0032606 |
27 |
0.280
|
Human |
|
|
response to virus
|
GO:0009615 |
126 |
0.278
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.277
|
|
|
|
defense response to virus
|
GO:0051607 |
71 |
0.276
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.257
|
Fly |
|
|
response to tumor necrosis factor
|
GO:0034612 |
76 |
0.250
|
Human |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.245
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.237
|
|
|
|
system process
|
GO:0003008 |
349 |
0.236
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.231
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.231
|
|
|
|
innate immune response activating signal transduction
|
GO:0002758 |
48 |
0.230
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.228
|
|
|
|
cellular response to lipopolysaccharide
|
GO:0071222 |
57 |
0.226
|
|
|
|
regulation of interferon beta production
|
GO:0032648 |
22 |
0.224
|
Human |
|
|
positive regulation of t cell cytokine production
|
GO:0002726 |
4 |
0.222
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.213
|
Fly |
|
|
regulation of interferon alpha production
|
GO:0032647 |
11 |
0.210
|
Human |
|
|
positive regulation of defense response to virus by host
|
GO:0002230 |
14 |
0.209
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.203
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.200
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.199
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.199
|
|
|
|
positive regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903557 |
22 |
0.198
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.195
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.193
|
|
|
|
regulation of lymphocyte activation
|
GO:0051249 |
103 |
0.190
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.190
|
|
|
|
negative regulation of multi organism process
|
GO:0043901 |
92 |
0.188
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.185
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.183
|
Fly |
|
|
regulation of type i interferon production
|
GO:0032479 |
26 |
0.179
|
Human |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.177
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.173
|
Fly |
|
|
necrotic cell death
|
GO:0070265 |
21 |
0.172
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.171
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.170
|
Fly |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.168
|
|
|
|
regulation of response to biotic stimulus
|
GO:0002831 |
55 |
0.167
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.166
|
|
|
|
type i interferon biosynthetic process
|
GO:0045351 |
4 |
0.165
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.165
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.164
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.162
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.158
|
|
|
|
endocytic recycling
|
GO:0032456 |
12 |
0.158
|
Fly |
|
|
tumor necrosis factor production
|
GO:0032640 |
43 |
0.154
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.153
|
Human |
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.151
|
|
|
|
neuronal action potential
|
GO:0019228 |
9 |
0.149
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.147
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.146
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.146
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.145
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.140
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.138
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.138
|
|
|
|
positive regulation of type i interferon mediated signaling pathway
|
GO:0060340 |
4 |
0.133
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.131
|
|
|
|
heart morphogenesis
|
GO:0003007 |
48 |
0.127
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.125
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.124
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.121
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.120
|
|
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.119
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.116
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.113
|
Human Fly |
|
|
neurological system process
|
GO:0050877 |
163 |
0.112
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.112
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.112
|
|
|
|
t cell activation
|
GO:0042110 |
99 |
0.109
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.105
|
|
|
|
cellular response to molecule of bacterial origin
|
GO:0071219 |
62 |
0.105
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.105
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.104
|
|
|
|
lymphocyte mediated immunity
|
GO:0002449 |
48 |
0.104
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.103
|
Fly |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.103
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.102
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.102
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.100
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.100
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.099
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.099
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.098
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.097
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.095
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.094
|
|
|
|
regulation of adaptive immune response
|
GO:0002819 |
33 |
0.094
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.093
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.093
|
|
|
|
positive regulation of extrinsic apoptotic signaling pathway
|
GO:2001238 |
26 |
0.093
|
|
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.093
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.092
|
Fly |
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.092
|
Fly |
|
|
cdc42 protein signal transduction
|
GO:0032488 |
4 |
0.091
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.091
|
|
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.091
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.091
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.091
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.090
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.090
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.090
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.090
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.086
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.086
|
|
|
|
skeletal muscle contraction
|
GO:0003009 |
16 |
0.086
|
|
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.086
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.084
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.084
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.084
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.083
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.083
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.083
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.083
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.080
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.079
|
|
|
|
transmission of nerve impulse
|
GO:0019226 |
11 |
0.079
|
|
|
|
muscle organ morphogenesis
|
GO:0048644 |
19 |
0.078
|
|
|
|
positive regulation of cytokine biosynthetic process
|
GO:0042108 |
25 |
0.077
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.077
|
Fly |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.076
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.074
|
|
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.074
|
|
|
|
regulation of mononuclear cell proliferation
|
GO:0032944 |
65 |
0.074
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.074
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.074
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.073
|
|
|
|
defense response to gram positive bacterium
|
GO:0050830 |
29 |
0.073
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.073
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.072
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.072
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.071
|
|
|
|
response to molecule of bacterial origin
|
GO:0002237 |
82 |
0.070
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.070
|
|
|
|
lipopolysaccharide mediated signaling pathway
|
GO:0031663 |
26 |
0.070
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.069
|
|
|
|
regulation of cytokine production involved in immune response
|
GO:0002718 |
22 |
0.066
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.066
|
Fly |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.065
|
|
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.065
|
|
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.064
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.064
|
Fly |
|
|
response to dsrna
|
GO:0043331 |
25 |
0.063
|
|
|
|
cellular ion homeostasis
|
GO:0006873 |
168 |
0.062
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.062
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.061
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.061
|
Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.059
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.059
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.058
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.058
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.058
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.058
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.057
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.057
|
|
|
|
negative regulation of immune effector process
|
GO:0002698 |
38 |
0.057
|
|
|
|
midgut development
|
GO:0007494 |
1 |
0.057
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.056
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.056
|
|
|
|
tube development
|
GO:0035295 |
125 |
0.055
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.055
|
|
|
|
calcium ion homeostasis
|
GO:0055074 |
122 |
0.054
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.054
|
|
|
|
neuron remodeling
|
GO:0016322 |
2 |
0.053
|
Fly |
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.053
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.053
|
|
|
|
thymus development
|
GO:0048538 |
3 |
0.053
|
|
|
|
hemostasis
|
GO:0007599 |
76 |
0.052
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.052
|
|
|
|
type i interferon signaling pathway
|
GO:0060337 |
11 |
0.051
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.051
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.051
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.051
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.050
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.050
|
Fly |
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.050
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.050
|
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.050
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.049
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.049
|
|
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.049
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.049
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.049
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.049
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.049
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.049
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.049
|
Fly |
|
|
gland development
|
GO:0048732 |
48 |
0.048
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.048
|
|
|
|
nik nf kappab signaling
|
GO:0038061 |
12 |
0.048
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.048
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.048
|
|
|
|
regulation of tumor necrosis factor production
|
GO:0032680 |
43 |
0.048
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.048
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.047
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.047
|
|
|
|
blood coagulation
|
GO:0007596 |
76 |
0.046
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.046
|
|
|
|
cellular calcium ion homeostasis
|
GO:0006874 |
117 |
0.045
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.045
|
Fly |
|
|
regulation of jak stat cascade
|
GO:0046425 |
44 |
0.045
|
Human |
|
|
interleukin 8 production
|
GO:0032637 |
51 |
0.045
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.045
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.044
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.044
|
Fly |
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.044
|
|
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.044
|
|
|
|
response to nitric oxide
|
GO:0071731 |
4 |
0.044
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.044
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.043
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.043
|
Fly |
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.043
|
|
|
|
cardiac muscle contraction
|
GO:0060048 |
34 |
0.043
|
|
|
|
elastic fiber assembly
|
GO:0048251 |
3 |
0.043
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.043
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.043
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.043
|
Fly |
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.042
|
|
|
|
positive regulation of immune effector process
|
GO:0002699 |
40 |
0.042
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.042
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.042
|
|
|
|
salivary gland morphogenesis
|
GO:0007435 |
4 |
0.042
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.041
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.041
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.041
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.041
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.041
|
|
|
|
visual behavior
|
GO:0007632 |
2 |
0.041
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.041
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.041
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.040
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.040
|
|
|
|
regulation of peptide transport
|
GO:0090087 |
62 |
0.039
|
|
|
|
multicellular organismal signaling
|
GO:0035637 |
34 |
0.038
|
|
|
|
mating
|
GO:0007618 |
1 |
0.037
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.037
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.037
|
Fly |
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.037
|
|
|
|
regulation of production of molecular mediator of immune response
|
GO:0002700 |
25 |
0.037
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.037
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.037
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.037
|
|
|
|
detection of stimulus involved in sensory perception
|
GO:0050906 |
43 |
0.037
|
|
|
|
cardiac ventricle morphogenesis
|
GO:0003208 |
20 |
0.036
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.036
|
|
|
|
somitogenesis
|
GO:0001756 |
2 |
0.036
|
|
|
|
response to lipopolysaccharide
|
GO:0032496 |
70 |
0.036
|
|
|
|
regulation of response to cytokine stimulus
|
GO:0060759 |
46 |
0.036
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.036
|
|
|
|
tumor necrosis factor superfamily cytokine production
|
GO:0071706 |
45 |
0.036
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.035
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.035
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.035
|
|
|
|
positive regulation of jak stat cascade
|
GO:0046427 |
35 |
0.035
|
|
|
|
cellular response to dsrna
|
GO:0071359 |
19 |
0.035
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.035
|
|
|
|
regulation of symbiosis encompassing mutualism through parasitism
|
GO:0043903 |
109 |
0.035
|
|
|
|
positive regulation of production of molecular mediator of immune response
|
GO:0002702 |
11 |
0.035
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.035
|
|
|
|
positive regulation of interleukin 2 production
|
GO:0032743 |
11 |
0.035
|
|
|
|
negative regulation of nf kappab transcription factor activity
|
GO:0032088 |
51 |
0.035
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.034
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.034
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.034
|
Fly |
|
|
protein import
|
GO:0017038 |
130 |
0.034
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.034
|
|
|
|
immunoglobulin secretion
|
GO:0048305 |
1 |
0.034
|
|
|
|
muscle tissue morphogenesis
|
GO:0060415 |
19 |
0.034
|
|
|
|
negative regulation of viral process
|
GO:0048525 |
66 |
0.034
|
|
|
|
multicellular organismal homeostasis
|
GO:0048871 |
67 |
0.034
|
Fly |
|
|
positive regulation of cytokine mediated signaling pathway
|
GO:0001961 |
12 |
0.034
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.034
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.034
|
|
|
|
cytokine production involved in immune response
|
GO:0002367 |
27 |
0.034
|
|
|
|
lymphocyte homeostasis
|
GO:0002260 |
4 |
0.034
|
|
|
|
aging
|
GO:0007568 |
66 |
0.033
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.033
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.033
|
Human Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.033
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.033
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.033
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.033
|
|
|
|
musculoskeletal movement
|
GO:0050881 |
17 |
0.033
|
|
|
|
ventricular cardiac muscle tissue development
|
GO:0003229 |
14 |
0.033
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.033
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.033
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.033
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.032
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.032
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.032
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.032
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.032
|
|
|
|
platelet formation
|
GO:0030220 |
4 |
0.032
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.032
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.032
|
|
|
|
vocalization behavior
|
GO:0071625 |
11 |
0.032
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.032
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.032
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.032
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.032
|
|
|
|
regulation of immunoglobulin production
|
GO:0002637 |
4 |
0.031
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.031
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.031
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.031
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.031
|
|
|
|
growth
|
GO:0040007 |
202 |
0.031
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.031
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.031
|
|
|
|
peroxisome organization
|
GO:0007031 |
28 |
0.031
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.031
|
|
|
|
t cell receptor signaling pathway
|
GO:0050852 |
21 |
0.030
|
|
|
|
regulation of lymphocyte mediated immunity
|
GO:0002706 |
33 |
0.030
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.030
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.030
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.030
|
|
|
|
transition metal ion transport
|
GO:0000041 |
23 |
0.030
|
|
|
|
positive regulation of response to external stimulus
|
GO:0032103 |
88 |
0.029
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.029
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.028
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.028
|
Fly |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.028
|
|
|
|
translation
|
GO:0006412 |
132 |
0.028
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.028
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.028
|
|
|
|
positive regulation of jun kinase activity
|
GO:0043507 |
23 |
0.028
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.028
|
|
|
|
myeloid leukocyte differentiation
|
GO:0002573 |
60 |
0.028
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.027
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.027
|
|
|
|
peptide transport
|
GO:0015833 |
74 |
0.027
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.027
|
|
|
|
leukocyte proliferation
|
GO:0070661 |
74 |
0.027
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.027
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.027
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.027
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.027
|
|
|
|
carbohydrate derivative biosynthetic process
|
GO:1901137 |
207 |
0.027
|
|
|
|
intracellular mrna localization
|
GO:0008298 |
1 |
0.027
|
|
|
|
divalent inorganic cation homeostasis
|
GO:0072507 |
136 |
0.026
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.026
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.026
|
|
|
|
positive regulation of interleukin 8 production
|
GO:0032757 |
36 |
0.026
|
|
|
|
antigen receptor mediated signaling pathway
|
GO:0050851 |
38 |
0.026
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.026
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.026
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.026
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.026
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.026
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.026
|
|
|
|
regulation of body fluid levels
|
GO:0050878 |
99 |
0.026
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.026
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.025
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.025
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.025
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.025
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.025
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.025
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.025
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.024
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.024
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.024
|
|
|
|
i kappab phosphorylation
|
GO:0007252 |
7 |
0.024
|
Mouse |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.024
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.024
|
|
|
|
nucleus localization
|
GO:0051647 |
1 |
0.024
|
|
|
|
metal ion homeostasis
|
GO:0055065 |
169 |
0.024
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.024
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.024
|
|
|
|
cardiac ventricle development
|
GO:0003231 |
23 |
0.023
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.023
|
|
|
|
response to exogenous dsrna
|
GO:0043330 |
10 |
0.023
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.023
|
Fly |
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.023
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.023
|
|
|
|
activation of jnkk activity
|
GO:0007256 |
1 |
0.023
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.023
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.023
|
|
|
|
cardiac chamber morphogenesis
|
GO:0003206 |
26 |
0.023
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.023
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.023
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.023
|
Fly |
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.022
|
Fly |
|
|
regulation of chemokine production
|
GO:0032642 |
31 |
0.022
|
|
|
|
cardiac chamber development
|
GO:0003205 |
30 |
0.022
|
|
|
|
negative regulation of secretion
|
GO:0051048 |
58 |
0.022
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.022
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.022
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.022
|
|
|
|
negative regulation of interferon beta production
|
GO:0032688 |
4 |
0.022
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.022
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.022
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.022
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.022
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.022
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.021
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.021
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.021
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.021
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.021
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.021
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.021
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.021
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.021
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.021
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.021
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.021
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.021
|
|
|
|
positive regulation of lymphocyte activation
|
GO:0051251 |
73 |
0.021
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.020
|
|
|
|
negative regulation of intracellular protein transport
|
GO:0090317 |
42 |
0.020
|
|
|
|
regulation of transcription factor import into nucleus
|
GO:0042990 |
39 |
0.020
|
|
|
|
anterior posterior pattern specification
|
GO:0009952 |
9 |
0.020
|
|
|
|
toll like receptor 2 signaling pathway
|
GO:0034134 |
4 |
0.020
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.020
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.020
|
|
|
|
peptide metabolic process
|
GO:0006518 |
51 |
0.020
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.020
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.020
|
|
