Homo sapiens

178 known processes

FLT1

fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)

(Aliases: VEGFR1,FLT)

FLT1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
vascular wound healing GO:0061042 4 1.000
angiogenesis involved in wound healing GO:0060055 4 1.000
regulation of glomerulus development GO:0090192 3 1.000
negative regulation of phosphatidylinositol biosynthetic process GO:0010512 2 1.000
regulation of vascular wound healing GO:0061043 2 1.000
positive regulation of transcription from rna polymerase ii promoter in response to hypoxia GO:0061419 2 1.000
positive regulation of vascular wound healing GO:0035470 1 1.000
positive regulation of peptidyl tyrosine autophosphorylation GO:1900086 1 1.000
positive regulation of histone deacetylase activity GO:1901727 3 1.000
positive regulation of glomerular mesangial cell proliferation GO:0072126 1 1.000
positive regulation of mast cell chemotaxis GO:0060754 4 1.000
regulation of mast cell chemotaxis GO:0060753 4 1.000
basophil chemotaxis GO:0002575 1 1.000
regulation of metanephric mesenchymal cell migration GO:2000589 2 1.000
vegf activated platelet derived growth factor receptor signaling pathway GO:0038086 3 1.000
Human
regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:1900238 2 1.000
positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway GO:0038033 4 1.000
regulation of glomerular mesangial cell proliferation GO:0072124 3 1.000
regulation of peptidyl tyrosine autophosphorylation GO:1900084 1 1.000
positive regulation of focal adhesion assembly GO:0051894 11 1.000
Human
positive regulation of p38mapk cascade GO:1900745 8 1.000
regulation of phosphatidylinositol biosynthetic process GO:0010511 5 1.000
positive regulation of metanephric mesenchymal cell migration by platelet derived growth factor receptor beta signaling pathway GO:0035793 2 1.000
positive regulation of metanephric mesenchymal cell migration GO:2000591 2 1.000
positive regulation of adherens junction organization GO:1903393 12 1.000
Human
platelet derived growth factor receptor beta signaling pathway GO:0035791 4 1.000
Human
positive regulation of cell proliferation by vegf activated platelet derived growth factor receptor signaling pathway GO:0038091 3 1.000
Human
sprouting angiogenesis GO:0002040 29 1.000
Zebrafish Mouse
cell migration involved in metanephros development GO:0035788 2 1.000
cell migration involved in kidney development GO:0035787 2 1.000
regulation of adherens junction organization GO:1903391 21 1.000
Human
regulation of cell proliferation involved in kidney development GO:1901722 3 1.000
positive regulation of metanephros development GO:0072216 3 1.000
positive regulation of phosphatidylinositol 3 kinase signaling GO:0014068 28 1.000
glomerular mesangial cell proliferation GO:0072110 3 1.000
positive regulation of protein localization to early endosome GO:1902966 2 0.999
regulation of smooth muscle cell proliferation GO:0048660 28 0.999
Human Rat
metanephric mesenchymal cell migration GO:0035789 2 0.999
regulation of focal adhesion assembly GO:0051893 20 0.999
Human
cell migration involved in sprouting angiogenesis GO:0002042 19 0.999
negative regulation of blood coagulation GO:0030195 22 0.999
Human
myeloid leukocyte migration GO:0097529 62 0.999
positive regulation of blood vessel endothelial cell migration GO:0043536 16 0.998
motor neuron axon guidance GO:0008045 2 0.998
negative regulation of hemostasis GO:1900047 22 0.998
Human
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.998
Human
glomerulus development GO:0032835 15 0.998
leukocyte migration GO:0050900 107 0.998
glycerolipid biosynthetic process GO:0045017 51 0.998
positive regulation of lipid metabolic process GO:0045834 50 0.998
positive regulation of map kinase activity GO:0043406 80 0.998
protein localization to early endosome GO:1902946 2 0.998
positive regulation of protein kinase c signaling GO:0090037 5 0.998
Human
cyclic nucleotide metabolic process GO:0009187 82 0.998
positive regulation of hyaluronan biosynthetic process GO:1900127 3 0.998
positive regulation of smooth muscle cell migration GO:0014911 6 0.998
Human
negative chemotaxis GO:0050919 11 0.997
positive regulation of receptor internalization GO:0002092 12 0.997
regulation of endothelial cell migration GO:0010594 67 0.997
Human
positive regulation of cell migration involved in sprouting angiogenesis GO:0090050 3 0.997
focal adhesion assembly GO:0048041 30 0.997
Human
calcium ion import GO:0070509 23 0.996
amine metabolic process GO:0009308 44 0.996
regulation of cell matrix adhesion GO:0001952 42 0.996
Human
leukocyte chemotaxis GO:0030595 76 0.995
regulation of receptor internalization GO:0002090 15 0.995
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.995
positive regulation of cell junction assembly GO:1901890 11 0.995
Human
regulation of cellular amine metabolic process GO:0033238 11 0.994
cellular lipid metabolic process GO:0044255 303 0.994
negative regulation of coagulation GO:0050819 24 0.994
Human
regulation of epithelial cell migration GO:0010632 93 0.994
Human
regulation of vascular permeability GO:0043114 11 0.994
regulation of histone deacetylase activity GO:1901725 3 0.993
kidney development GO:0001822 53 0.993
positive regulation of endothelial cell proliferation GO:0001938 37 0.993
Human
regulation of map kinase activity GO:0043405 108 0.992
branching morphogenesis of an epithelial tube GO:0048754 19 0.992
Mouse
regulation of cell migration involved in sprouting angiogenesis GO:0090049 9 0.992
coagulation GO:0050817 78 0.992
Human
cellular response to vascular endothelial growth factor stimulus GO:0035924 26 0.992
regulation of chemotaxis GO:0050920 74 0.992
Human
positive regulation of vascular permeability GO:0043117 4 0.991
regulation of protein localization to early endosome GO:1902965 2 0.991
renal system development GO:0072001 63 0.991
Fly
positive regulation of smooth muscle cell proliferation GO:0048661 14 0.990
Human Rat
vascular process in circulatory system GO:0003018 29 0.990
vasculature development GO:0001944 181 0.990
regulation of cyclic nucleotide metabolic process GO:0030799 63 0.989
ion transmembrane transport GO:0034220 338 0.989
positive regulation of cell matrix adhesion GO:0001954 23 0.989
Human
regulation of axon extension involved in axon guidance GO:0048841 2 0.989
regulation of hemostasis GO:1900046 42 0.989
Human
regulation of cell junction assembly GO:1901888 29 0.989
Human
chemical homeostasis within a tissue GO:0048875 3 0.988
urogenital system development GO:0001655 65 0.988
Fly
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.988
Human
receptor internalization GO:0031623 43 0.988
cell substrate adherens junction assembly GO:0007045 30 0.988
Human
system process GO:0003008 349 0.986
Zebrafish Rat
positive regulation of cell substrate adhesion GO:0010811 37 0.985
Human
ureteric bud development GO:0001657 13 0.985
glycerophospholipid metabolic process GO:0006650 84 0.985
circulatory system development GO:0072359 262 0.984
chemotaxis GO:0006935 157 0.984
positive regulation of leukocyte chemotaxis GO:0002690 38 0.984
endothelial cell migration GO:0043542 86 0.984
Human
positive regulation of protein kinase activity GO:0045860 190 0.984
regulation of cell motility GO:2000145 299 0.984
muscle cell migration GO:0014812 19 0.984
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.983
cardiovascular system development GO:0072358 262 0.983
blood vessel development GO:0001568 172 0.983
positive regulation of cell adhesion GO:0045785 84 0.983
Human
mapk cascade GO:0000165 288 0.981
transmembrane transport GO:0055085 399 0.980
blood vessel endothelial cell migration GO:0043534 42 0.980
adherens junction organization GO:0034332 36 0.980
Human
epithelial cell migration GO:0010631 119 0.980
Human Fly
ureteric bud morphogenesis GO:0060675 10 0.980
cellular ketone metabolic process GO:0042180 80 0.980
negative regulation of platelet activation GO:0010544 7 0.979
Human
regulation of cell migration GO:0030334 289 0.978
cell proliferation involved in kidney development GO:0072111 3 0.978
regulation of cellular component biogenesis GO:0044087 281 0.977
Human
regulation of axon guidance GO:1902667 3 0.977
nephron development GO:0072006 30 0.977
regulation of cell adhesion GO:0030155 166 0.977
Human
regulation of leukocyte chemotaxis GO:0002688 46 0.975
positive regulation of transmembrane transport GO:0034764 41 0.975
positive regulation of cellular component organization GO:0051130 376 0.974
Human
positive regulation of phosphatidylinositol 3 kinase activity GO:0043552 12 0.974
positive regulation of cellular amine metabolic process GO:0033240 7 0.973
positive regulation of positive chemotaxis GO:0050927 13 0.973
Human
adherens junction assembly GO:0034333 34 0.972
Human
regulation of coagulation GO:0050818 44 0.972
Human
positive regulation of epithelial cell proliferation GO:0050679 65 0.972
Human
mesonephric epithelium development GO:0072163 14 0.971
positive regulation of ion transport GO:0043270 87 0.970
positive regulation of protein kinase b signaling GO:0051897 42 0.969
cell substrate adhesion GO:0031589 132 0.969
Human
positive regulation of phosphorylation GO:0042327 394 0.968
regulation of locomotion GO:0040012 329 0.966
blood vessel morphogenesis GO:0048514 162 0.966
mesonephros development GO:0001823 17 0.966
granulocyte chemotaxis GO:0071621 37 0.965
taxis GO:0042330 157 0.964
blood circulation GO:0008015 113 0.964
Zebrafish
branching involved in ureteric bud morphogenesis GO:0001658 9 0.964
cellular amino acid metabolic process GO:0006520 116 0.963
muscle cell proliferation GO:0033002 35 0.963
Human Rat
endothelial cell proliferation GO:0001935 65 0.962
Human
regulation of lipid metabolic process GO:0019216 96 0.961
activation of protein kinase b activity GO:0032148 14 0.961
mesonephric tubule development GO:0072164 14 0.959
vascular endothelial growth factor signaling pathway GO:0038084 15 0.959
regulation of endothelial cell differentiation GO:0045601 4 0.958
endothelial cell chemotaxis GO:0035767 13 0.958
negative regulation of lipid metabolic process GO:0045833 38 0.958
phosphatidylinositol mediated signaling GO:0048015 55 0.954
regulation of cell substrate adhesion GO:0010810 68 0.954
Human
nephron tubule morphogenesis GO:0072078 13 0.954
kidney vasculature development GO:0061440 7 0.954
lipid metabolic process GO:0006629 381 0.953
cellular component morphogenesis GO:0032989 314 0.952
Human Fly
tissue migration GO:0090130 119 0.952
Human Fly
glycerolipid metabolic process GO:0046486 107 0.951
lipid biosynthetic process GO:0008610 177 0.950
organ morphogenesis GO:0009887 147 0.949
Fly
metanephros development GO:0001656 16 0.949
regulation of protein serine threonine kinase activity GO:0071900 179 0.949
cation transport GO:0006812 331 0.949
positive regulation of fibroblast proliferation GO:0048146 21 0.948
Human Rat
granulocyte migration GO:0097530 40 0.947
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.946
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.946
cell chemotaxis GO:0060326 112 0.945
cell cell junction organization GO:0045216 69 0.943
Human
phospholipid metabolic process GO:0006644 99 0.943
smooth muscle cell proliferation GO:0048659 28 0.942
Human Rat
regulation of protein kinase c signaling GO:0090036 8 0.942
Human
regulation of wound healing GO:0061041 56 0.941
Human
ameboidal type cell migration GO:0001667 135 0.938
Human Fly
positive regulation of behavior GO:0048520 60 0.938
Human
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 35 0.938
regulation of cellular component movement GO:0051270 334 0.937
regulation of polysaccharide biosynthetic process GO:0032885 20 0.937
cellular response to growth factor stimulus GO:0071363 197 0.937
regulation of protein kinase activity GO:0045859 289 0.935
positive regulation of cellular component movement GO:0051272 181 0.935
epithelium migration GO:0090132 119 0.934
Human Fly
peptidyl tyrosine phosphorylation GO:0018108 170 0.933
positive regulation of chemotaxis GO:0050921 57 0.932
Human
cell matrix adhesion GO:0007160 85 0.932
Human
positive regulation of cell proliferation involved in kidney development GO:1901724 1 0.928
peptidyl tyrosine modification GO:0018212 170 0.928
renal tubule development GO:0061326 19 0.926
Fly
positive regulation of cyclin dependent protein serine threonine kinase activity GO:0045737 15 0.925
signal transduction by phosphorylation GO:0023014 297 0.924
glomerulus vasculature development GO:0072012 6 0.923
regulation of blood coagulation GO:0030193 42 0.922
Human
positive chemotaxis GO:0050918 33 0.920
Human
regulation of transferase activity GO:0051338 355 0.919
calcium ion transport GO:0006816 147 0.917
positive regulation of cell migration GO:0030335 172 0.917
cell substrate junction assembly GO:0007044 35 0.917
Human
regulation of vasculature development GO:1901342 97 0.914
positive regulation of epithelial cell migration GO:0010634 55 0.912
Human
kidney epithelium development GO:0072073 25 0.912
protein kinase c signaling GO:0070528 17 0.911
Human
positive regulation of dna metabolic process GO:0051054 73 0.911
Human
blood coagulation GO:0007596 76 0.910
Human
cellular response to endogenous stimulus GO:0071495 336 0.909
Human Fly
regulation of endothelial cell proliferation GO:0001936 56 0.909
Human
positive regulation of glomerulus development GO:0090193 1 0.909
nephron morphogenesis GO:0072028 15 0.909
dna replication GO:0006260 116 0.907
Human
regulation of leukocyte migration GO:0002685 63 0.906
negative regulation of cell death GO:0060548 345 0.906
Human Fly
regulation of peptidase activity GO:0052547 180 0.905
forebrain generation of neurons GO:0021872 3 0.905
regulation of kinase activity GO:0043549 314 0.905
p38mapk cascade GO:0038066 9 0.903
smooth muscle cell migration GO:0014909 18 0.900
Human
lung alveolus development GO:0048286 4 0.900
response to decreased oxygen levels GO:0036293 96 0.897
Mouse Rat
cardiac vascular smooth muscle cell differentiation GO:0060947 2 0.897
single organism cell adhesion GO:0098602 179 0.896
Human
positive regulation of leukocyte migration GO:0002687 46 0.895
angiogenesis GO:0001525 147 0.894
cell junction assembly GO:0034329 67 0.893
Human
positive regulation of wound healing GO:0090303 20 0.893
mucopolysaccharide metabolic process GO:1903510 27 0.889
nephron epithelium development GO:0072009 23 0.889
nephron epithelium morphogenesis GO:0072088 15 0.886
positive regulation of dna replication GO:0045740 35 0.883
Human
anatomical structure formation involved in morphogenesis GO:0048646 284 0.883
behavior GO:0007610 112 0.883
Human
memory GO:0007613 3 0.882
regulation of metanephros development GO:0072215 4 0.882
negative regulation of multicellular organismal process GO:0051241 317 0.879
Human
regulation of behavior GO:0050795 82 0.878
Human
vascular endothelial growth factor receptor signaling pathway GO:0048010 19 0.878
negative regulation of cell migration GO:0030336 102 0.877
positive regulation of angiogenesis GO:0045766 51 0.876
response to growth factor GO:0070848 205 0.875
receptor metabolic process GO:0043112 81 0.871
regulation of blood vessel endothelial cell migration GO:0043535 30 0.871
protein autophosphorylation GO:0046777 123 0.870
regulation of ion transmembrane transport GO:0034765 132 0.870
protein processing GO:0016485 226 0.865
positive regulation of endothelial cell chemotaxis GO:2001028 5 0.859
positive regulation of immune system process GO:0002684 283 0.859
Mouse
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.855
regulation of mapk cascade GO:0043408 262 0.853
regulation of receptor mediated endocytosis GO:0048259 32 0.852
cell activation GO:0001775 213 0.848
Human
regulation of stress activated mapk cascade GO:0032872 84 0.844
Human
protein deacetylation GO:0006476 38 0.843
positive regulation of calcium ion transport GO:0051928 51 0.836
cgmp metabolic process GO:0046068 19 0.833
positive regulation of cellular component biogenesis GO:0044089 158 0.832
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.832
Human
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.831
Human
regulation of lipid biosynthetic process GO:0046890 47 0.831
organophosphate biosynthetic process GO:0090407 163 0.828
positive regulation of cell migration by vascular endothelial growth factor signaling pathway GO:0038089 5 0.828
positive regulation of cell proliferation GO:0008284 301 0.826
Human Rat
circulatory system process GO:0003013 113 0.822
Zebrafish
vascular smooth muscle cell development GO:0097084 1 0.821
regulation of phosphatidylinositol 3 kinase activity GO:0043551 14 0.818
cellular amine metabolic process GO:0044106 41 0.815
induction of positive chemotaxis GO:0050930 8 0.814
positive regulation of cell division GO:0051781 59 0.814
salivary gland morphogenesis GO:0007435 4 0.813
Fly
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.813
luteolysis GO:0001554 3 0.812
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.812
Human
platelet activation GO:0030168 44 0.806
Human
connective tissue development GO:0061448 39 0.805
positive regulation of axon extension GO:0045773 4 0.802
positive regulation of calcium ion import GO:0090280 6 0.801
platelet derived growth factor receptor signaling pathway GO:0048008 14 0.800
Human
regulation of response to wounding GO:1903034 101 0.799
Human
positive regulation of transferase activity GO:0051347 227 0.797
regulation of calcium ion transport GO:0051924 79 0.792
positive regulation of cell cycle process GO:0090068 106 0.790
response to hypoxia GO:0001666 96 0.789
Mouse Rat
peptidyl serine phosphorylation GO:0018105 101 0.788
single organismal cell cell adhesion GO:0016337 148 0.786
Human
regulation of purine nucleotide metabolic process GO:1900542 264 0.784
enzyme linked receptor protein signaling pathway GO:0007167 303 0.782
positive regulation of kinase activity GO:0033674 204 0.781
renal tubule morphogenesis GO:0061333 14 0.778
Fly
positive regulation of ion transmembrane transport GO:0034767 40 0.773
regulation of mesonephros development GO:0061217 3 0.768
negative regulation of platelet derived growth factor receptor signaling pathway GO:0010642 4 0.766
regulation of endothelial cell chemotaxis GO:2001026 9 0.762
hematopoietic or lymphoid organ development GO:0048534 186 0.758
Human Mouse Fly
regulation of cgmp metabolic process GO:0030823 9 0.758
regulation of cell activation GO:0050865 125 0.755
Human
negative regulation of locomotion GO:0040013 118 0.755
regulation of smooth muscle cell migration GO:0014910 15 0.755
Human
regulation of angiogenesis GO:0045765 92 0.753
positive regulation of stress activated protein kinase signaling cascade GO:0070304 61 0.751
Human
regulation of lipid kinase activity GO:0043550 19 0.750
positive regulation of endothelial cell migration GO:0010595 39 0.749
Human
negative regulation of response to external stimulus GO:0032102 83 0.746
Human
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.738
response to organic cyclic compound GO:0014070 204 0.733
inositol lipid mediated signaling GO:0048017 55 0.729
peptidyl serine modification GO:0018209 106 0.727
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.725
Human
positive regulation of transcription from rna polymerase ii promoter in response to stress GO:0036003 9 0.716
positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0030949 6 0.715
positive regulation of axon extension involved in axon guidance GO:0048842 1 0.713
positive regulation of dna biosynthetic process GO:2000573 8 0.710
biological adhesion GO:0022610 331 0.709
Human
regulation of anatomical structure morphogenesis GO:0022603 286 0.708
positive regulation of cell cycle GO:0045787 140 0.703
protein deacylation GO:0035601 39 0.703
substrate dependent cerebral cortex tangential migration GO:0021825 2 0.697
regulation of dna metabolic process GO:0051052 153 0.696
Human
regulation of transmembrane transport GO:0034762 139 0.689
divalent metal ion transport GO:0070838 152 0.686
single organism carbohydrate metabolic process GO:0044723 193 0.684
negative regulation of response to wounding GO:1903035 47 0.682
Human
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.679
Human
regulation of mitosis GO:0007088 63 0.669
regulation of protein autophosphorylation GO:0031952 15 0.664
regulation of triglyceride metabolic process GO:0090207 11 0.664
carbohydrate biosynthetic process GO:0016051 42 0.662
cellular response to hypoxia GO:0071456 51 0.662
protein kinase b signaling GO:0043491 69 0.659
neuron projection development GO:0031175 106 0.658
regulation of histone deacetylation GO:0031063 9 0.658
nervous system development GO:0007399 293 0.657
Fly
regulation of peptidyl serine phosphorylation GO:0033135 50 0.657
regulation of cell morphogenesis GO:0022604 153 0.654
Human Fly
regulation of kidney development GO:0090183 10 0.653
regulation of nucleotide metabolic process GO:0006140 269 0.652
post embryonic organ development GO:0048569 1 0.650
Fly
regulation of epithelial cell proliferation GO:0050678 113 0.649
Human
neuron death GO:0070997 65 0.647
regulation of platelet activation GO:0010543 9 0.646
Human
carbohydrate derivative biosynthetic process GO:1901137 207 0.644
regulation of cell cell adhesion GO:0022407 57 0.642
cellular response to hormone stimulus GO:0032870 125 0.639
Fly
morphogenesis of a branching structure GO:0001763 21 0.637
Mouse
monocyte chemotaxis GO:0002548 20 0.636
epithelial cell proliferation GO:0050673 128 0.635
Human
positive regulation of response to wounding GO:1903036 28 0.622
regulation of response to external stimulus GO:0032101 222 0.622
Human
branching involved in salivary gland morphogenesis GO:0060445 1 0.621
regulation of cysteine type endopeptidase activity GO:2000116 127 0.621
positive regulation of chromatin modification GO:1903310 30 0.620
peptidyl tyrosine autophosphorylation GO:0038083 5 0.616
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.615
regulation of hematopoietic progenitor cell differentiation GO:1901532 24 0.612
Mouse
regulation of nuclear division GO:0051783 65 0.609
regulation of retinal ganglion cell axon guidance GO:0090259 1 0.607
regulation of protein kinase b signaling GO:0051896 61 0.604
regulation of dna replication GO:0006275 68 0.604
Human
phospholipid biosynthetic process GO:0008654 44 0.601
surfactant homeostasis GO:0043129 3 0.599
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.599
Human
positive regulation of cell differentiation GO:0045597 211 0.597
Mouse
response to estradiol GO:0032355 23 0.589
leukocyte differentiation GO:0002521 98 0.588
regulation of calcium ion import GO:0090279 11 0.588
immune system development GO:0002520 195 0.579
Human Mouse Fly
mitotic cell cycle process GO:1903047 286 0.578
Fly
negative regulation of cellular component movement GO:0051271 106 0.578
regulation of cell cycle process GO:0010564 266 0.577
stress activated protein kinase signaling cascade GO:0031098 94 0.577
Human
cell morphogenesis GO:0000902 296 0.576
Human Fly
chromatin modification GO:0016568 298 0.576
negative regulation of endopeptidase activity GO:0010951 84 0.570
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 17 0.566
immune response GO:0006955 307 0.559
Human Fly
negative regulation of axon extension GO:0030517 2 0.559
cell junction organization GO:0034330 79 0.557
Human
positive regulation of mesonephros development GO:0061213 2 0.556
negative regulation of neuron apoptotic process GO:0043524 23 0.555
negative regulation of peptidase activity GO:0010466 91 0.551
metal ion transport GO:0030001 272 0.551
positive regulation of endocytosis GO:0045807 42 0.541
response to lipid GO:0033993 206 0.539
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.537
Human
regulation of cellular response to x ray GO:2000683 2 0.537
negative regulation of phospholipid biosynthetic process GO:0071072 3 0.535
negative regulation of protein metabolic process GO:0051248 391 0.533
glycerophospholipid biosynthetic process GO:0046474 40 0.532
phosphatidylinositol metabolic process GO:0046488 53 0.531
cerebral cortex cell migration GO:0021795 3 0.531
neuron differentiation GO:0030182 138 0.527
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.521
erk1 and erk2 cascade GO:0070371 104 0.515
Human
polysaccharide metabolic process GO:0005976 33 0.515
anion transport GO:0006820 161 0.512
regulation of cellular ketone metabolic process GO:0010565 50 0.510
positive regulation of neural precursor cell proliferation GO:2000179 2 0.505
macromolecule deacylation GO:0098732 41 0.499
cellular response to oxygen containing compound GO:1901701 276 0.490
Fly
tissue morphogenesis GO:0048729 96 0.489
Mouse Fly
cell adhesion GO:0007155 325 0.488
Human
negative regulation of cell proliferation GO:0008285 228 0.487
epithelium development GO:0060429 227 0.486
Mouse Fly
phosphatidylinositol biosynthetic process GO:0006661 25 0.486
positive regulation of protein complex assembly GO:0031334 86 0.484
secretion GO:0046903 254 0.481
Human
covalent chromatin modification GO:0016569 254 0.479
negative regulation of axon guidance GO:1902668 1 0.479
reactive oxygen species metabolic process GO:0072593 75 0.478
positive regulation of protein phosphorylation GO:0001934 313 0.478
histone modification GO:0016570 251 0.477
regulation of cellular amino acid metabolic process GO:0006521 6 0.474
positive regulation of mitotic cell cycle GO:0045931 60 0.470
cell division GO:0051301 168 0.468
positive regulation of mitosis GO:0045840 25 0.467
regulation of protein tyrosine kinase activity GO:0061097 36 0.467
Human
positive regulation of transport GO:0051050 336 0.463
Human
divalent inorganic cation transport GO:0072511 158 0.462
response to wounding GO:0009611 168 0.462
Human
negative regulation of lipid biosynthetic process GO:0051055 22 0.462
positive regulation of response to external stimulus GO:0032103 88 0.460
Human
aminoglycan biosynthetic process GO:0006023 29 0.455
phosphatidylinositol 3 kinase signaling GO:0014065 48 0.453
kidney morphogenesis GO:0060993 19 0.451
response to oxygen levels GO:0070482 100 0.450
Mouse Rat
response to organonitrogen compound GO:0010243 156 0.444
Fly
regulation of reactive oxygen species metabolic process GO:2000377 41 0.442
nephron tubule development GO:0072080 17 0.439
positive regulation of hydrolase activity GO:0051345 331 0.425
small gtpase mediated signal transduction GO:0007264 78 0.424
regulation of fibroblast proliferation GO:0048145 32 0.424
Human Rat
negative regulation of apoptotic process GO:0043066 316 0.423
Human Fly
positive regulation of tyrosine phosphorylation of stat3 protein GO:0042517 16 0.422
Human
regulation of vasculogenesis GO:2001212 3 0.419
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.417
regulation of body fluid levels GO:0050878 99 0.413
Human
negative regulation of catalytic activity GO:0043086 335 0.412
regulation of metal ion transport GO:0010959 120 0.410
negative regulation of cellular protein metabolic process GO:0032269 353 0.407
negative regulation of axonogenesis GO:0050771 4 0.407
cellular response to decreased oxygen levels GO:0036294 51 0.403
cellular response to oxygen levels GO:0071453 55 0.403
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.400
organophosphate catabolic process GO:0046434 430 0.398
positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 2 0.395
regulation of neuron apoptotic process GO:0043523 35 0.393
regulation of cellular response to growth factor stimulus GO:0090287 76 0.391
platelet derived growth factor receptor alpha signaling pathway GO:0035790 1 0.390
Human
positive regulation of locomotion GO:0040017 186 0.386
tube development GO:0035295 125 0.384
Mouse Fly
regulation of mitotic cell cycle GO:0007346 189 0.382
cellular metal ion homeostasis GO:0006875 146 0.382
Human
monocyte differentiation GO:0030224 15 0.372
response to biotic stimulus GO:0009607 276 0.371
Fly
regulation of phospholipid biosynthetic process GO:0071071 7 0.366
regulation of ion transport GO:0043269 189 0.365
glycosaminoglycan metabolic process GO:0030203 35 0.365
chromatin organization GO:0006325 351 0.363
wound healing GO:0042060 115 0.363
Human
polysaccharide biosynthetic process GO:0000271 27 0.362
negative regulation of wound healing GO:0061045 25 0.361
Human
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.361
carbohydrate metabolic process GO:0005975 207 0.359
regulation of protein maturation GO:1903317 150 0.357
positive regulation of cell motility GO:2000147 177 0.355
positive regulation of histone deacetylation GO:0031065 6 0.353
telencephalon cell migration GO:0022029 4 0.352
regulation of cell projection organization GO:0031344 107 0.344
positive regulation of cell development GO:0010720 92 0.343
neurological system process GO:0050877 163 0.343
response to drug GO:0042493 81 0.341
protein localization to organelle GO:0033365 280 0.340
patterning of blood vessels GO:0001569 2 0.336
Mouse
positive regulation of organelle organization GO:0010638 195 0.335
negative regulation of protein processing GO:0010955 142 0.334
regulation of carbohydrate metabolic process GO:0006109 54 0.332
ion homeostasis GO:0050801 230 0.327
Human
mitotic cell cycle GO:0000278 326 0.326
Fly
morphogenesis of a branching epithelium GO:0061138 20 0.325
Mouse
response to steroid hormone GO:0048545 80 0.323
hematopoietic progenitor cell differentiation GO:0002244 38 0.323
Mouse
cell projection organization GO:0030030 252 0.322
Fly
positive regulation of phospholipase activity GO:0010518 22 0.321
cranial nerve development GO:0021545 4 0.321
cell type specific apoptotic process GO:0097285 125 0.315
Human
negative regulation of proteolysis GO:0045861 132 0.313
long term memory GO:0007616 2 0.313
response to oxygen containing compound GO:1901700 369 0.313
Fly
regulation of polysaccharide metabolic process GO:0032881 21 0.308
regulation of protein processing GO:0070613 150 0.307
lung vasculature development GO:0060426 2 0.307
mitotic nuclear division GO:0007067 119 0.305

FLT1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.773
inherited metabolic disorder DOID:655 242 0.773