IMP
Process View
negative regulation of platelet activation
Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of platelet activation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.994 | Human | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.993 | Human | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.989 | Human | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.981 | ||
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.979 | Human | |
| NRP1 | neuropilin 1 | 0.951 | ||
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.819 | ||
| PGF | placental growth factor | 0.682 | Human | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.637 | ||
| C1QA | complement component 1, q subcomponent, A chain | 0.592 | Human | |
| EGFR | epidermal growth factor receptor | 0.455 | ||
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine | 0.386 | ||
| SYK | spleen tyrosine kinase | 0.283 | ||
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.172 | ||
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.130 | ||
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.109 | ||
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.094 | ||
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.079 | ||
| APOC1 | apolipoprotein C-I | 0.056 | ||
| A2M | alpha-2-macroglobulin | 0.056 | ||
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.051 | ||
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.047 | ||
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.041 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.040 | ||
| COL6A1 | collagen, type VI, alpha 1 | 0.040 | ||
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.039 | ||
| CDCP1 | CUB domain containing protein 1 | 0.036 | ||
| C1QC | complement component 1, q subcomponent, C chain | 0.034 | Human | |
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.033 | ||
| PTEN | phosphatase and tensin homolog | 0.029 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.025 | ||
| CYBA | cytochrome b-245, alpha polypeptide | 0.024 | ||
| C1QB | complement component 1, q subcomponent, B chain | 0.023 | Human | |
| LDLR | low density lipoprotein receptor | 0.021 | ||
| GAB1 | GRB2-associated binding protein 1 | 0.020 | ||
| HP | haptoglobin | 0.019 | ||
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.018 | ||
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.018 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.017 | ||
| GAB2 | GRB2-associated binding protein 2 | 0.015 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.014 | ||
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.014 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.013 | ||
| TBC1D10A | TBC1 domain family, member 10A | 0.013 | ||
| ALB | albumin | 0.013 | ||
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.013 | ||
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.012 | ||
| SLA | Src-like-adaptor | 0.011 | ||
| ROBO4 | roundabout homolog 4, magic roundabout (Drosophila) | 0.011 | ||
| KITLG | KIT ligand | 0.011 | ||
| LAT | linker for activation of T cells | 0.010 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.010 |