Homo sapiens

0 known processes

NSMAF

neutral sphingomyelinase (N-SMase) activation associated factor

(Aliases: FAN)

NSMAF biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular amino acid metabolic process GO:0006521 6 0.144
purine ribonucleoside metabolic process GO:0046128 437 0.134
regulation of cellular ketone metabolic process GO:0010565 50 0.124
cellular amine metabolic process GO:0044106 41 0.110
amine metabolic process GO:0009308 44 0.110
cellular amino acid metabolic process GO:0006520 116 0.108
cytoplasmic transport GO:0016482 379 0.103
regulation of cellular amine metabolic process GO:0033238 11 0.095
nucleoside triphosphate metabolic process GO:0009141 422 0.094
morphogenesis of embryonic epithelium GO:0016331 4 0.087
protein localization to organelle GO:0033365 280 0.085
cellular ketone metabolic process GO:0042180 80 0.085
vesicle mediated transport GO:0016192 371 0.084
post embryonic development GO:0009791 2 0.077
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.073
intracellular protein transport GO:0006886 270 0.072
response to external biotic stimulus GO:0043207 261 0.069
negative regulation of multicellular organismal process GO:0051241 317 0.066
embryonic epithelial tube formation GO:0001838 4 0.066
response to other organism GO:0051707 261 0.064
cell projection organization GO:0030030 252 0.060
primary neural tube formation GO:0014020 3 0.054
atp metabolic process GO:0046034 176 0.053
organophosphate catabolic process GO:0046434 430 0.051
positive regulation of cellular catabolic process GO:0031331 284 0.051
purine nucleoside triphosphate metabolic process GO:0009144 412 0.049
positive regulation of organelle organization GO:0010638 195 0.049
motor neuron axon guidance GO:0008045 2 0.049
response to biotic stimulus GO:0009607 276 0.048
nucleotide catabolic process GO:0009166 408 0.047
anatomical structure formation involved in morphogenesis GO:0048646 284 0.047
regulation of cell migration GO:0030334 289 0.047
ribonucleoside triphosphate metabolic process GO:0009199 412 0.046
regulation of establishment of protein localization GO:0070201 242 0.046
ribonucleotide catabolic process GO:0009261 405 0.044
purine containing compound catabolic process GO:0072523 411 0.044
positive regulation of cellular amine metabolic process GO:0033240 7 0.044
atp catabolic process GO:0006200 157 0.044
actin filament based process GO:0030029 224 0.043
ribonucleoside monophosphate metabolic process GO:0009161 187 0.042
positive regulation of phosphorylation GO:0042327 394 0.042
purine nucleotide catabolic process GO:0006195 405 0.042
purine nucleoside monophosphate metabolic process GO:0009126 186 0.041
purine nucleoside monophosphate catabolic process GO:0009128 158 0.041
purine nucleoside triphosphate catabolic process GO:0009146 392 0.041
transmembrane transport GO:0055085 399 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.040
regulation of cytokine production GO:0001817 232 0.039
nucleoside monophosphate metabolic process GO:0009123 191 0.039
positive regulation of catabolic process GO:0009896 310 0.039
nuclear transport GO:0051169 179 0.038
cellular response to dna damage stimulus GO:0006974 379 0.038
neural tube formation GO:0001841 3 0.038
immune response GO:0006955 307 0.038
positive regulation of cellular component organization GO:0051130 376 0.038
dephosphorylation GO:0016311 209 0.038
regulation of protein localization GO:0032880 296 0.037
nucleoside triphosphate catabolic process GO:0009143 394 0.037
single organism cellular localization GO:1902580 332 0.036
nucleocytoplasmic transport GO:0006913 176 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
regulation of intracellular transport GO:0032386 195 0.034
negative regulation of phosphorus metabolic process GO:0010563 267 0.034
positive regulation of protein phosphorylation GO:0001934 313 0.034
ribonucleoside triphosphate catabolic process GO:0009203 391 0.034
nucleoside catabolic process GO:0009164 408 0.034
regulation of cell cycle GO:0051726 393 0.034
positive regulation of transport GO:0051050 336 0.033
nervous system development GO:0007399 293 0.033
negative regulation of phosphate metabolic process GO:0045936 267 0.033
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.033
cell growth GO:0016049 160 0.033
nucleoside monophosphate catabolic process GO:0009125 159 0.033
positive regulation of cell proliferation GO:0008284 301 0.033
cell morphogenesis GO:0000902 296 0.033
cellular lipid metabolic process GO:0044255 303 0.032
multicellular organismal aging GO:0010259 3 0.032
purine nucleoside catabolic process GO:0006152 398 0.032
innate immune response GO:0045087 178 0.031
cellular component morphogenesis GO:0032989 314 0.031
vasculature development GO:0001944 181 0.031
organonitrogen compound biosynthetic process GO:1901566 200 0.030
apoptotic signaling pathway GO:0097190 268 0.030
tube development GO:0035295 125 0.030
anion transport GO:0006820 161 0.030
regulation of locomotion GO:0040012 329 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
nitrogen compound transport GO:0071705 191 0.029
system process GO:0003008 349 0.028
regulation of cell cycle process GO:0010564 266 0.028
epithelium migration GO:0090132 119 0.028
positive regulation of locomotion GO:0040017 186 0.028
axon regeneration GO:0031103 1 0.028
neuron differentiation GO:0030182 138 0.028
response to virus GO:0009615 126 0.028
positive regulation of intracellular protein transport GO:0090316 76 0.027
generation of neurons GO:0048699 152 0.027
lipid biosynthetic process GO:0008610 177 0.027
determination of adult lifespan GO:0008340 2 0.027
mitotic cell cycle phase transition GO:0044772 162 0.027
lipid metabolic process GO:0006629 381 0.026
positive regulation of developmental process GO:0051094 314 0.026
negative regulation of cellular protein metabolic process GO:0032269 353 0.026
regulation of meiotic cell cycle GO:0051445 4 0.026
regeneration GO:0031099 4 0.026
regulation of protein targeting GO:1903533 91 0.026
membrane organization GO:0061024 292 0.026
mitotic cell cycle process GO:1903047 286 0.026
ribonucleoside catabolic process GO:0042454 406 0.026
cellular response to endogenous stimulus GO:0071495 336 0.026
protein catabolic process GO:0030163 325 0.025
regulation of cellular component movement GO:0051270 334 0.025
cell cycle phase transition GO:0044770 173 0.025
actin cytoskeleton organization GO:0030036 207 0.025
regulation of intracellular protein transport GO:0033157 123 0.025
defense response to bacterium GO:0042742 63 0.025
tissue migration GO:0090130 119 0.025
negative regulation of ruffle assembly GO:1900028 3 0.025
regulation of mitotic cell cycle GO:0007346 189 0.025
reactive nitrogen species metabolic process GO:2001057 3 0.025
mitotic cell cycle GO:0000278 326 0.024
regulation of anatomical structure morphogenesis GO:0022603 286 0.024
ion transmembrane transport GO:0034220 338 0.024
inorganic ion transmembrane transport GO:0098660 231 0.024
actin mediated cell contraction GO:0070252 12 0.024
protein localization to nucleus GO:0034504 136 0.024
response to oxygen containing compound GO:1901700 369 0.024
positive regulation of protein transport GO:0051222 135 0.024
negative regulation of cell death GO:0060548 345 0.024
negative regulation of catalytic activity GO:0043086 335 0.024
tissue morphogenesis GO:0048729 96 0.024
regulation of phosphatase activity GO:0010921 81 0.024
purine ribonucleotide catabolic process GO:0009154 404 0.024
tube closure GO:0060606 3 0.023
positive regulation of cytoplasmic transport GO:1903651 82 0.023
metal ion transport GO:0030001 272 0.023
negative regulation of cytokine production GO:0001818 82 0.023
regulation of protein transport GO:0051223 213 0.023
carbohydrate derivative biosynthetic process GO:1901137 207 0.023
negative regulation of programmed cell death GO:0043069 321 0.023
regulation of cytoskeleton organization GO:0051493 177 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
regulation of cell differentiation GO:0045595 393 0.022
organic hydroxy compound metabolic process GO:1901615 147 0.022
protein targeting GO:0006605 187 0.022
female gamete generation GO:0007292 2 0.021
glycosyl compound catabolic process GO:1901658 413 0.021
protein oligomerization GO:0051259 173 0.021
plasma membrane organization GO:0007009 115 0.021
negative regulation of cellular amine metabolic process GO:0033239 3 0.021
negative regulation of hydrolase activity GO:0051346 182 0.021
positive regulation of protein complex assembly GO:0031334 86 0.021
neuron development GO:0048666 113 0.021
positive regulation of response to external stimulus GO:0032103 88 0.021
neuron projection regeneration GO:0031102 1 0.021
positive regulation of intracellular transport GO:0032388 104 0.021
defense response GO:0006952 315 0.020
negative regulation of apoptotic process GO:0043066 316 0.020
regulation of nucleotide catabolic process GO:0030811 205 0.020
growth GO:0040007 202 0.020
regulation of protein localization to nucleus GO:1900180 85 0.020
cell projection morphogenesis GO:0048858 129 0.020
cell division GO:0051301 168 0.020
neural tube closure GO:0001843 3 0.020
cytokine production GO:0001816 247 0.020
endocytosis GO:0006897 159 0.020
nucleoside phosphate catabolic process GO:1901292 412 0.020
defense response to other organism GO:0098542 129 0.020
endomembrane system organization GO:0010256 196 0.019
regulation of cell growth GO:0001558 135 0.019
peptidyl tyrosine phosphorylation GO:0018108 170 0.019
single organism membrane organization GO:0044802 268 0.019
cell aging GO:0007569 52 0.019
cell part morphogenesis GO:0032990 137 0.019
covalent chromatin modification GO:0016569 254 0.019
carbohydrate metabolic process GO:0005975 207 0.019
jak stat cascade GO:0007259 46 0.019
single organism cell adhesion GO:0098602 179 0.019
organelle fission GO:0048285 149 0.019
cellular response to cytokine stimulus GO:0071345 181 0.019
blood vessel morphogenesis GO:0048514 162 0.018
regulation of cell morphogenesis GO:0022604 153 0.018
protein import GO:0017038 130 0.018
dendritic spine morphogenesis GO:0060997 3 0.018
peptidyl serine modification GO:0018209 106 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.018
peptidyl tyrosine modification GO:0018212 170 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.018
regulation of nucleotide metabolic process GO:0006140 269 0.018
response to wounding GO:0009611 168 0.018
cation transmembrane transport GO:0098655 238 0.017
regulation of cell motility GO:2000145 299 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
positive regulation of cellular component movement GO:0051272 181 0.017
maintenance of location GO:0051235 112 0.017
alcohol metabolic process GO:0006066 114 0.017
enzyme linked receptor protein signaling pathway GO:0007167 303 0.017
regulation of cytoplasmic transport GO:1903649 149 0.017
actin filament organization GO:0007015 128 0.017
lipid localization GO:0010876 106 0.017
protein targeting to nucleus GO:0044744 104 0.017
positive regulation of immune response GO:0050778 159 0.017
response to growth factor GO:0070848 205 0.017
dna repair GO:0006281 198 0.017
negative regulation of cell motility GO:2000146 104 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
cell morphogenesis involved in differentiation GO:0000904 144 0.016
ribonucleoside monophosphate catabolic process GO:0009158 158 0.016
regulation of mitotic cell cycle phase transition GO:1901990 118 0.016
chromatin organization GO:0006325 351 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
positive regulation of cell migration GO:0030335 172 0.016
positive regulation of cytokine production GO:0001819 167 0.016
response to acid chemical GO:0001101 66 0.016
anatomical structure homeostasis GO:0060249 100 0.016
rna interference GO:0016246 4 0.016
positive regulation of mapk cascade GO:0043410 190 0.016
myoblast fusion GO:0007520 1 0.016
segmentation GO:0035282 4 0.016
lymphocyte activation GO:0046649 133 0.016
regulation of protein kinase activity GO:0045859 289 0.016
rna processing GO:0006396 255 0.016
positive regulation of protein localization to nucleus GO:1900182 48 0.015
regulation of protein complex assembly GO:0043254 147 0.015
regulation of dephosphorylation GO:0035303 96 0.015
immune effector process GO:0002252 159 0.015
positive regulation of cytoskeleton organization GO:0051495 83 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
cellular response to organic cyclic compound GO:0071407 127 0.015
regulation of nucleocytoplasmic transport GO:0046822 98 0.015
cellular response to lipid GO:0071396 127 0.015
small molecule biosynthetic process GO:0044283 157 0.015
actin polymerization or depolymerization GO:0008154 56 0.015
negative regulation of cell migration GO:0030336 102 0.015
taxis GO:0042330 157 0.015
organic anion transport GO:0015711 103 0.015
positive regulation of cell motility GO:2000147 177 0.015
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.015
regulation of protein import into nucleus GO:0042306 78 0.015
inorganic cation transmembrane transport GO:0098662 194 0.015
meiotic chromosome segregation GO:0045132 4 0.015
glycoprotein metabolic process GO:0009100 110 0.015
positive regulation of cellular component biogenesis GO:0044089 158 0.015
negative regulation of protein modification process GO:0031400 200 0.015
vacuole organization GO:0007033 44 0.015
regulation of transferase activity GO:0051338 355 0.015
regulation of vasculature development GO:1901342 97 0.015
syncytium formation by plasma membrane fusion GO:0000768 2 0.015
positive regulation of kinase activity GO:0033674 204 0.015
internal protein amino acid acetylation GO:0006475 101 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
positive regulation of cell death GO:0010942 263 0.014
hemopoiesis GO:0030097 180 0.014
regulation of cellular response to stress GO:0080135 244 0.014
striated muscle contraction GO:0006941 52 0.014
negative regulation of cell cycle phase transition GO:1901988 89 0.014
actin filament based movement GO:0030048 17 0.014
chemotaxis GO:0006935 157 0.014
positive regulation of transferase activity GO:0051347 227 0.014
positive regulation of proteolysis GO:0045862 142 0.014
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.014
regulation of growth GO:0040008 165 0.014
regulation of response to external stimulus GO:0032101 222 0.014
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.014
mitochondrion organization GO:0007005 156 0.014
replicative cell aging GO:0001302 3 0.014
negative regulation of locomotion GO:0040013 118 0.014
neuron projection development GO:0031175 106 0.014
blastoderm segmentation GO:0007350 2 0.014
cellular response to abiotic stimulus GO:0071214 117 0.014
cellular macromolecule catabolic process GO:0044265 380 0.014
neuromuscular junction development GO:0007528 3 0.014
negative regulation of protein phosphorylation GO:0001933 140 0.014
positive regulation of immune system process GO:0002684 283 0.014
cellular response to hormone stimulus GO:0032870 125 0.014
cellular chemical homeostasis GO:0055082 180 0.013
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.013
cell projection assembly GO:0030031 126 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
cellular protein complex assembly GO:0043623 188 0.013
regulation of angiogenesis GO:0045765 92 0.013
circulatory system development GO:0072359 262 0.013
divalent inorganic cation transport GO:0072511 158 0.013
single organism nuclear import GO:1902593 104 0.013
oogenesis GO:0048477 2 0.013
negative regulation of cell cycle GO:0045786 193 0.013
response to bacterium GO:0009617 144 0.013
glycerolipid metabolic process GO:0046486 107 0.013
regulation of purine nucleotide catabolic process GO:0033121 205 0.013
regulation of apoptotic signaling pathway GO:2001233 175 0.013
neuronal action potential GO:0019228 9 0.013
negative regulation of phosphatase activity GO:0010923 61 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
protein import into nucleus GO:0006606 104 0.013
regulation of cysteine type endopeptidase activity GO:2000116 127 0.013
dna replication GO:0006260 116 0.013
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.013
positive regulation of protein import into nucleus GO:0042307 46 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
response to lipopolysaccharide GO:0032496 70 0.012
locomotory behavior GO:0007626 1 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
ameboidal type cell migration GO:0001667 135 0.012
positive regulation of defense response GO:0031349 87 0.012
central nervous system development GO:0007417 123 0.012
single organismal cell cell adhesion GO:0016337 148 0.012
cell cycle checkpoint GO:0000075 117 0.012
chromatin modification GO:0016568 298 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
muscle system process GO:0003012 81 0.012
histone modification GO:0016570 251 0.012
protein maturation GO:0051604 233 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
regulation of cell cycle phase transition GO:1901987 126 0.012
response to nitrogen compound GO:1901698 184 0.012
cation transport GO:0006812 331 0.012
anterior posterior axis specification GO:0009948 2 0.012
neurogenesis GO:0022008 169 0.012
positive regulation of growth GO:0045927 58 0.012
ubiquitin dependent protein catabolic process GO:0006511 206 0.012
regulation of nucleoside metabolic process GO:0009118 209 0.012
chemical homeostasis GO:0048878 306 0.012
neurological system process GO:0050877 163 0.012
negative regulation of protein metabolic process GO:0051248 391 0.012
golgi vesicle transport GO:0048193 80 0.012
hindbrain development GO:0030902 3 0.012
salivary gland morphogenesis GO:0007435 4 0.012
embryo development GO:0009790 123 0.012
regulation of cellular component biogenesis GO:0044087 281 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
peripheral nervous system development GO:0007422 2 0.011
response to lipid GO:0033993 206 0.011
cellular ion homeostasis GO:0006873 168 0.011
epithelial cell differentiation GO:0030855 141 0.011
response to hormone GO:0009725 175 0.011
regulation of gtp catabolic process GO:0033124 180 0.011
immune system development GO:0002520 195 0.011
autophagy GO:0006914 88 0.011
regulation of protein processing GO:0070613 150 0.011
response to organic cyclic compound GO:0014070 204 0.011
regulation of cellular component size GO:0032535 82 0.011
negative regulation of epithelial cell migration GO:0010633 38 0.011
positive regulation of angiogenesis GO:0045766 51 0.011
protein acetylation GO:0006473 116 0.011
mitotic nuclear division GO:0007067 119 0.011
regulation of actin filament length GO:0030832 56 0.011
protein autophosphorylation GO:0046777 123 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
immune response activating signal transduction GO:0002757 90 0.011
phospholipid metabolic process GO:0006644 99 0.011
leukocyte mediated immunity GO:0002443 59 0.011
small molecule catabolic process GO:0044282 92 0.011
regulation of membrane potential GO:0042391 95 0.011
epithelial cell migration GO:0010631 119 0.011
ion homeostasis GO:0050801 230 0.011
negative regulation of cell proliferation GO:0008285 228 0.011
nuclear import GO:0051170 106 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
signal transduction by phosphorylation GO:0023014 297 0.011
ncrna metabolic process GO:0034660 108 0.011
anterior posterior axis specification embryo GO:0008595 2 0.011
response to axon injury GO:0048678 1 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
cellular metal ion homeostasis GO:0006875 146 0.011
memory GO:0007613 3 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
muscle structure development GO:0061061 98 0.010
positive regulation of cell cycle GO:0045787 140 0.010
tissue regeneration GO:0042246 3 0.010
biological adhesion GO:0022610 331 0.010
protein localization to membrane GO:0072657 160 0.010
response to abiotic stimulus GO:0009628 336 0.010
adult locomotory behavior GO:0008344 1 0.010
reproductive process GO:0022414 106 0.010
sensory perception GO:0007600 103 0.010
positive regulation of protein kinase activity GO:0045860 190 0.010
organelle inheritance GO:0048308 2 0.010
glycoprotein biosynthetic process GO:0009101 91 0.010
regulation of immune response GO:0050776 201 0.010
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.010
regulation of kinase activity GO:0043549 314 0.010
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.010
dna damage checkpoint GO:0000077 68 0.010
interspecies interaction between organisms GO:0044419 156 0.010
carboxylic acid biosynthetic process GO:0046394 97 0.010

NSMAF disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.122
neurodegenerative disease DOID:1289 102 0.122
nervous system disease DOID:863 431 0.122
musculoskeletal system disease DOID:17 223 0.016
auditory system disease DOID:2742 53 0.015
sensory system disease DOID:0050155 203 0.015
disease of metabolism DOID:0014667 295 0.014
cancer DOID:162 167 0.012
disease of cellular proliferation DOID:14566 174 0.012
inherited metabolic disorder DOID:655 242 0.011
organ system cancer DOID:0050686 164 0.010
nonsyndromic deafness DOID:0050563 50 0.010