|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.991
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.976
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.917
|
Worm |
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.916
|
Mouse |
|
|
telomere capping
|
GO:0016233 |
5 |
0.880
|
Fly |
|
|
telomere maintenance via telomere lengthening
|
GO:0010833 |
9 |
0.852
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.852
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.846
|
Fly |
|
|
dna double strand break processing
|
GO:0000729 |
10 |
0.844
|
Fly |
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.825
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.819
|
Fly |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.808
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.805
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.798
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.795
|
Fly |
|
|
response to radiation
|
GO:0009314 |
151 |
0.772
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.763
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.755
|
Fly |
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.733
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.729
|
Mouse |
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.721
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.713
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.695
|
|
|
|
anatomical structure homeostasis
|
GO:0060249 |
100 |
0.630
|
Fly |
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
0.560
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.556
|
Mouse Fly |
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
0.540
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.538
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.532
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.500
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.494
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.491
|
Fly |
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.487
|
|
|
|
replication fork processing
|
GO:0031297 |
13 |
0.487
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.477
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.475
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.462
|
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.440
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.428
|
Fly |
|
|
positive regulation of telomere maintenance
|
GO:0032206 |
4 |
0.422
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.420
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.418
|
|
|
|
telomere maintenance
|
GO:0000723 |
32 |
0.410
|
Fly |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.403
|
Fly |
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.391
|
|
|
|
dna damage induced protein phosphorylation
|
GO:0006975 |
5 |
0.386
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.386
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.366
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.363
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.361
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.361
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.352
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.348
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.347
|
|
|
|
double strand break repair via single strand annealing
|
GO:0045002 |
4 |
0.341
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.340
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.332
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.328
|
|
|
|
protein localization to chromosome telomeric region
|
GO:0070198 |
6 |
0.326
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.324
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.321
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.299
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.278
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.275
|
Fly |
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.275
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
31 |
0.274
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.271
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.270
|
Fly |
|
|
regulation of protein autophosphorylation
|
GO:0031952 |
15 |
0.268
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.262
|
Fly |
|
|
regulation of telomere maintenance via telomerase
|
GO:0032210 |
6 |
0.250
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.247
|
|
|
|
dna catabolic process exonucleolytic
|
GO:0000738 |
17 |
0.246
|
Fly |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.234
|
|
|
|
double strand break repair via homologous recombination
|
GO:0000724 |
50 |
0.232
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.230
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.223
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.219
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.219
|
|
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
0.218
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.217
|
Fly |
|
|
cytokine production
|
GO:0001816 |
247 |
0.217
|
|
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.217
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.216
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.212
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.201
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.199
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.194
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.193
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.183
|
Mouse |
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.180
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.179
|
Mouse |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.178
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.176
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.171
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.168
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.166
|
|
|
|
positive regulation of homeostatic process
|
GO:0032846 |
47 |
0.162
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.161
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.159
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.157
|
Fly |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.157
|
|
|
|
positive regulation of i kappab kinase nf kappab signaling
|
GO:0043123 |
132 |
0.156
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.155
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.153
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.151
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.150
|
|
|
|
meiosis i
|
GO:0007127 |
4 |
0.149
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.146
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.145
|
|
|
|
regulation of response to dna damage stimulus
|
GO:2001020 |
94 |
0.145
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.143
|
|
|
|
glycoprotein metabolic process
|
GO:0009100 |
110 |
0.142
|
|
|
|
positive regulation of cytokine production
|
GO:0001819 |
167 |
0.140
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.140
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.139
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.134
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.129
|
|
|
|
i kappab kinase nf kappab signaling
|
GO:0007249 |
166 |
0.128
|
|
|
|
dna catabolic process
|
GO:0006308 |
49 |
0.126
|
Fly |
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.126
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.126
|
|
|
|
cytokine mediated signaling pathway
|
GO:0019221 |
109 |
0.124
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.124
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.122
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.121
|
Mouse |
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.119
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.116
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.116
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.115
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.113
|
|
|
|
genetic imprinting
|
GO:0071514 |
1 |
0.111
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.111
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.110
|
|
|
|
regulation of epithelial cell proliferation
|
GO:0050678 |
113 |
0.108
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.108
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.107
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.105
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.105
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.105
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.104
|
Mouse Fly |
|
|
b cell activation
|
GO:0042113 |
33 |
0.103
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.103
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.102
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.101
|
Fly |
|
|
oogenesis
|
GO:0048477 |
2 |
0.100
|
Mouse Fly |
|
|
histone h4 acetylation
|
GO:0043967 |
47 |
0.100
|
|
|
|
rna dependent dna replication
|
GO:0006278 |
16 |
0.096
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.096
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.095
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.094
|
Mouse |
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.094
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.093
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.093
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.092
|
|
|
|
negative regulation of telomerase activity
|
GO:0051974 |
6 |
0.091
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.089
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.088
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.088
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.088
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.086
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.085
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.085
|
|
|
|
regulation of telomere maintenance
|
GO:0032204 |
13 |
0.084
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.083
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.083
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.083
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.082
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.080
|
Mouse Fly |
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.079
|
|
|
|
dna duplex unwinding
|
GO:0032508 |
30 |
0.078
|
|
|
|
histone h3 k4 methylation
|
GO:0051568 |
27 |
0.077
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.076
|
|
|
|
system process
|
GO:0003008 |
349 |
0.075
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.074
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.074
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.074
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.074
|
Fly |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.074
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.074
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.072
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.072
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.072
|
|
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.071
|
|
|
|
positive regulation of t cell proliferation
|
GO:0042102 |
33 |
0.071
|
|
|
|
protein glycosylation
|
GO:0006486 |
62 |
0.070
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.069
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.069
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.069
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.068
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.068
|
|
|
|
somatic diversification of immunoglobulins involved in immune response
|
GO:0002208 |
3 |
0.068
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.068
|
|
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.067
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.067
|
|
|
|
macromolecule glycosylation
|
GO:0043413 |
63 |
0.066
|
|
|
|
histone h4 k12 acetylation
|
GO:0043983 |
6 |
0.065
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.065
|
|
|
|
negative regulation of t cell apoptotic process
|
GO:0070233 |
4 |
0.063
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.062
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.062
|
|
|
|
protein alkylation
|
GO:0008213 |
74 |
0.062
|
|
|
|
intra s dna damage checkpoint
|
GO:0031573 |
4 |
0.061
|
|
|
|
negative regulation of protein catabolic process
|
GO:0042177 |
59 |
0.061
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.061
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.061
|
Mouse Fly |
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.060
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.059
|
|
|
|
reciprocal dna recombination
|
GO:0035825 |
4 |
0.059
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.059
|
|
|
|
protein adp ribosylation
|
GO:0006471 |
9 |
0.058
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.058
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.058
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.058
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.058
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.057
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.056
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.056
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.056
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.055
|
|
|
|
growth
|
GO:0040007 |
202 |
0.055
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.055
|
Mouse |
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.054
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.054
|
|
|
|
regulation of protein binding
|
GO:0043393 |
66 |
0.054
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.053
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.052
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.052
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.052
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.052
|
|
|
|
production of molecular mediator of immune response
|
GO:0002440 |
37 |
0.051
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.051
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.050
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.050
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.050
|
|
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.050
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.050
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.050
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.049
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.049
|
|
|
|
telomere organization
|
GO:0032200 |
33 |
0.049
|
Fly |
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.049
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.049
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.048
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.048
|
|
|
|
reciprocal meiotic recombination
|
GO:0007131 |
4 |
0.048
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.047
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.047
|
|
|
|
positive regulation of immunoglobulin mediated immune response
|
GO:0002891 |
4 |
0.046
|
|
|
|
negative regulation of telomere maintenance via telomerase
|
GO:0032211 |
5 |
0.046
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.046
|
Mouse Worm |
|
|
adipose tissue development
|
GO:0060612 |
2 |
0.045
|
|
|
|
positive regulation of nf kappab transcription factor activity
|
GO:0051092 |
81 |
0.044
|
|
|
|
telomere maintenance via telomerase
|
GO:0007004 |
8 |
0.044
|
|
|
|
negative regulation of telomere maintenance
|
GO:0032205 |
9 |
0.044
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.044
|
Fly |
|
|
dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator
|
GO:0006978 |
11 |
0.043
|
|
|
|
negative regulation of cell growth
|
GO:0030308 |
83 |
0.043
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.043
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.042
|
Mouse |
|
|
negative regulation of growth
|
GO:0045926 |
97 |
0.042
|
|
|
|
somatic recombination of immunoglobulin gene segments
|
GO:0016447 |
4 |
0.042
|
|
|
|
recombinational repair
|
GO:0000725 |
50 |
0.042
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.042
|
|
|
|
sister chromatid segregation
|
GO:0000819 |
54 |
0.042
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.042
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.041
|
Fly |
|
|
dna biosynthetic process
|
GO:0071897 |
40 |
0.041
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.041
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.040
|
|
|
|
negative regulation of response to dna damage stimulus
|
GO:2001021 |
33 |
0.040
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.040
|
|
|
|
dna geometric change
|
GO:0032392 |
32 |
0.040
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.040
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.040
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.039
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.038
|
Mouse |
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.038
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.038
|
|
|
|
regulation of autophagy
|
GO:0010506 |
52 |
0.038
|
|
|
|
positive regulation of protein import into nucleus
|
GO:0042307 |
46 |
0.038
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.038
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.038
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.037
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.037
|
Mouse Worm Fly |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.037
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.037
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.037
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.037
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.037
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.037
|
Mouse |
|
|
negative regulation of dna dependent dna replication
|
GO:2000104 |
9 |
0.036
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.036
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
4 |
0.036
|
|
|
|
lymphocyte apoptotic process
|
GO:0070227 |
20 |
0.036
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.036
|
|
|
|
neuromuscular process
|
GO:0050905 |
15 |
0.036
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.036
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.035
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.035
|
Fly |
|
|
interleukin 1 beta production
|
GO:0032611 |
22 |
0.035
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.035
|
|
|
|
regulation of histone acetylation
|
GO:0035065 |
19 |
0.035
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.035
|
|
|
|
positive regulation of cell activation
|
GO:0050867 |
81 |
0.034
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.034
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.034
|
|
|
|
cellular cation homeostasis
|
GO:0030003 |
163 |
0.034
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.034
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.034
|
|
|
|
dna damage response signal transduction resulting in transcription
|
GO:0042772 |
12 |
0.034
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.034
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.033
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.033
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.033
|
|
|
|
positive regulation of dna metabolic process
|
GO:0051054 |
73 |
0.033
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.033
|
Fly |
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.033
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.033
|
|
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
0.033
|
|
|
|
regulation of neuron apoptotic process
|
GO:0043523 |
35 |
0.032
|
Mouse |
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.032
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.032
|
Worm |
|
|
cell growth
|
GO:0016049 |
160 |
0.032
|
|
|
|
regulation of interleukin 1 production
|
GO:0032652 |
21 |
0.032
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.032
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.032
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.032
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.032
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.032
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.031
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.031
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.031
|
|
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.031
|
|
|
|
neuromuscular process controlling balance
|
GO:0050885 |
7 |
0.031
|
|
|
|
positive regulation of cytokine secretion
|
GO:0050715 |
42 |
0.031
|
|
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.031
|
|
|
|
positive regulation vascular endothelial growth factor production
|
GO:0010575 |
12 |
0.031
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.030
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.030
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.030
|
|
|
|
protein homooligomerization
|
GO:0051260 |
100 |
0.030
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.030
|
|
|
|
negative regulation of homeostatic process
|
GO:0032845 |
59 |
0.030
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.030
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.030
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.030
|
|
|
|
interleukin 1 production
|
GO:0032612 |
26 |
0.030
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.030
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.030
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.030
|
|
|
|
response to alcohol
|
GO:0097305 |
64 |
0.029
|
|
|
|
positive regulation of response to dna damage stimulus
|
GO:2001022 |
43 |
0.029
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.029
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.029
|
|
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.029
|
|
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
7 |
0.028
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.028
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.028
|
|
|
|
regulation of viral process
|
GO:0050792 |
103 |
0.028
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.028
|
|
|
|
cation homeostasis
|
GO:0055080 |
189 |
0.028
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.028
|
|
|
|
negative regulation of phosphatase activity
|
GO:0010923 |
61 |
0.028
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.028
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.028
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.027
|
|
|
|
positive regulation of secretion
|
GO:0051047 |
116 |
0.027
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.027
|
|
|
|
positive regulation of calcium ion transport
|
GO:0051928 |
51 |
0.027
|
|
|
|
viral process
|
GO:0016032 |
146 |
0.027
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.027
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.027
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.027
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.027
|
|
|
|
dosage compensation
|
GO:0007549 |
3 |
0.026
|
|
|
|
regulation of interleukin 1 beta production
|
GO:0032651 |
18 |
0.026
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.026
|
|
|
|
regulation of phosphatase activity
|
GO:0010921 |
81 |
0.026
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.026
|
|
|
|
retina homeostasis
|
GO:0001895 |
42 |
0.026
|
Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.026
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.026
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.026
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.025
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.025
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.025
|
|
|
|
double strand break repair via nonhomologous end joining
|
GO:0006303 |
10 |
0.025
|
|
|
|
positive regulation of dna damage response signal transduction by p53 class mediator
|
GO:0043517 |
8 |
0.025
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.025
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.025
|
|
|
|
lipid storage
|
GO:0019915 |
28 |
0.025
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.025
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.025
|
|
|
|
amide transport
|
GO:0042886 |
76 |
0.025
|
|
|
|
negative regulation of protein k63 linked ubiquitination
|
GO:1900045 |
4 |
0.024
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.024
|
|
|
|
negative regulation of binding
|
GO:0051100 |
57 |
0.024
|
|
|
|
negative regulation of cellular catabolic process
|
GO:0031330 |
83 |
0.024
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.024
|
|
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.024
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.024
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.024
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.024
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.024
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.024
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.024
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.024
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.023
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.023
|
|
|
|
regulation of double strand break repair via homologous recombination
|
GO:0010569 |
11 |
0.023
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.023
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.023
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.023
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.023
|
|
|
|
regulation of dna dependent dna replication
|
GO:0090329 |
19 |
0.023
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.023
|
|
|
|
cytokine secretion
|
GO:0050663 |
64 |
0.023
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.023
|
|
|
|
leukocyte mediated immunity
|
GO:0002443 |
59 |
0.023
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.023
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.022
|
|
|
|
cellular metal ion homeostasis
|
GO:0006875 |
146 |
0.022
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.022
|
|
|
|
neuron death
|
GO:0070997 |
65 |
0.022
|
Mouse Fly |
|
|
positive regulation of protein modification by small protein conjugation or removal
|
GO:1903322 |
61 |
0.022
|
|
|
|
thymocyte apoptotic process
|
GO:0070242 |
2 |
0.022
|
|
|
|
positive regulation of interleukin 1 beta secretion
|
GO:0050718 |
11 |
0.022
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.022
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.022
|
|
|
|
regulation of dna endoreduplication
|
GO:0032875 |
5 |
0.022
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.022
|
|
|
|
negative regulation of dephosphorylation
|
GO:0035305 |
63 |
0.022
|
|
|
|
non recombinational repair
|
GO:0000726 |
14 |
0.022
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.022
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.022
|
|
|
|
protein methylation
|
GO:0006479 |
74 |
0.022
|
|
|
|
hair follicle morphogenesis
|
GO:0031069 |
2 |
0.021
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.021
|
|
|
|
developmental growth
|
GO:0048589 |
48 |
0.021
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.021
|
Mouse Worm |
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.021
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.021
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.021
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.021
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator
|
GO:0042771 |
23 |
0.021
|
|
|
|
monovalent inorganic cation homeostasis
|
GO:0055067 |
37 |
0.021
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.021
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.021
|
|
|
|
tissue regeneration
|
GO:0042246 |
3 |
0.021
|
|
|
|
glycosylation
|
GO:0070085 |
71 |
0.021
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.021
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.021
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.021
|
|
|
|
regulation of lymphocyte apoptotic process
|
GO:0070228 |
15 |
0.021
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.021
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.020
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.020
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.020
|
|
|
|
protein secretion
|
GO:0009306 |
98 |
0.020
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.020
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.020
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.020
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.020
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.020
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.020
|
|
|
|
negative regulation of histone h3 k9 methylation
|
GO:0051573 |
3 |
0.020
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.019
|
|
|
|
dna catabolic process endonucleolytic
|
GO:0000737 |
37 |
0.019
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.019
|
|
|
|
extrinsic apoptotic signaling pathway in absence of ligand
|
GO:0097192 |
22 |
0.019
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.019
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.019
|
|
|
|
protein poly adp ribosylation
|
GO:0070212 |
3 |
0.019
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.019
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.019
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.019
|
|
|
|
regulation of defense response to bacterium
|
GO:1900424 |
2 |
0.019
|
|
|
|
aging
|
GO:0007568 |
66 |
0.019
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.019
|
Mouse Fly |
|
|
negative regulation of cellular protein catabolic process
|
GO:1903363 |
38 |
0.018
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.018
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.018
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.018
|
|
