Homo sapiens

21 known processes

TTI1

Tel2 interacting protein 1 homolog (S. pombe)

(Aliases: KIAA0406)

TTI1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular response to dna damage stimulus GO:0006974 379 0.355
cell cycle checkpoint GO:0000075 117 0.343
regulation of tor signaling GO:0032006 30 0.340
response to uv GO:0009411 73 0.306
dna damage checkpoint GO:0000077 68 0.303
determination of adult lifespan GO:0008340 2 0.297
Worm
post embryonic development GO:0009791 2 0.249
histone h2a acetylation GO:0043968 12 0.247
response to abiotic stimulus GO:0009628 336 0.246
response to radiation GO:0009314 151 0.241
female gamete generation GO:0007292 2 0.224
dna integrity checkpoint GO:0031570 71 0.214
anatomical structure homeostasis GO:0060249 100 0.199
actin filament based process GO:0030029 224 0.187
negative regulation of cell cycle phase transition GO:1901988 89 0.181
cellular response to uv GO:0034644 32 0.178
telomere organization GO:0032200 33 0.177
mitotic cell cycle GO:0000278 326 0.175
dna damage induced protein phosphorylation GO:0006975 5 0.161
meiotic chromosome segregation GO:0045132 4 0.148
small nucleolar ribonucleoprotein complex assembly GO:0000491 3 0.145
tor signaling GO:0031929 39 0.144
multicellular organismal aging GO:0010259 3 0.140
Worm
peptidyl serine phosphorylation GO:0018105 101 0.136
response to caffeine GO:0031000 3 0.120
histone exchange GO:0043486 3 0.106
lipid metabolic process GO:0006629 381 0.104
cellular amino acid metabolic process GO:0006520 116 0.102
chromatin organization GO:0006325 351 0.101
response to ionizing radiation GO:0010212 65 0.097
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.093
regulation of cell cycle process GO:0010564 266 0.093
mrna metabolic process GO:0016071 175 0.092
negative regulation of cell cycle GO:0045786 193 0.090
cellular amine metabolic process GO:0044106 41 0.087
mitotic dna replication checkpoint GO:0033314 2 0.086
response to organic cyclic compound GO:0014070 204 0.086
cellular ketone metabolic process GO:0042180 80 0.085
covalent chromatin modification GO:0016569 254 0.084
dna recombination GO:0006310 77 0.083
peptidyl lysine modification GO:0018205 144 0.079
chromatin modification GO:0016568 298 0.078
anatomical structure formation involved in morphogenesis GO:0048646 284 0.076
peptidyl serine modification GO:0018209 106 0.075
cellular macromolecular complex assembly GO:0034622 324 0.073
regulation of cellular amino acid metabolic process GO:0006521 6 0.072
internal peptidyl lysine acetylation GO:0018393 97 0.069
nucleoside triphosphate catabolic process GO:0009143 394 0.068
circulatory system development GO:0072359 262 0.068
protein localization to organelle GO:0033365 280 0.067
dna repair GO:0006281 198 0.066
embryo development GO:0009790 123 0.066
nucleoside phosphate catabolic process GO:1901292 412 0.066
internal protein amino acid acetylation GO:0006475 101 0.065
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.065
nucleoside monophosphate catabolic process GO:0009125 159 0.065
recombinational repair GO:0000725 50 0.064
microtubule based process GO:0007017 210 0.061
regulation of cellular ketone metabolic process GO:0010565 50 0.059
ribonucleoprotein complex subunit organization GO:0071826 81 0.059
histone h4 acetylation GO:0043967 47 0.058
vesicle mediated transport GO:0016192 371 0.058
cellular response to ionizing radiation GO:0071479 32 0.057
phospholipid metabolic process GO:0006644 99 0.056
heart development GO:0007507 95 0.056
cellular component morphogenesis GO:0032989 314 0.055
cellular response to abiotic stimulus GO:0071214 117 0.054
cell cycle phase transition GO:0044770 173 0.052
cardiovascular system development GO:0072358 262 0.052
positive regulation of cellular amine metabolic process GO:0033240 7 0.052
oogenesis GO:0048477 2 0.052
regulation of growth rate GO:0040009 1 0.050
cell division GO:0051301 168 0.049
reproductive structure development GO:0048608 55 0.049
negative regulation of cell cycle process GO:0010948 121 0.049
regulation of protein binding GO:0043393 66 0.047
actin filament organization GO:0007015 128 0.047
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.047
mitotic cell cycle process GO:1903047 286 0.047
cell aging GO:0007569 52 0.045
mitotic dna damage checkpoint GO:0044773 28 0.044
protein autophosphorylation GO:0046777 123 0.043
microtubule cytoskeleton organization GO:0000226 176 0.042
purine containing compound catabolic process GO:0072523 411 0.042
actin cytoskeleton organization GO:0030036 207 0.042
intracellular protein transport GO:0006886 270 0.041
protein acetylation GO:0006473 116 0.041
cell morphogenesis GO:0000902 296 0.041
organelle fission GO:0048285 149 0.041
mitotic cell cycle phase transition GO:0044772 162 0.040
cellular response to organic cyclic compound GO:0071407 127 0.040
amine metabolic process GO:0009308 44 0.039
protein localization to nucleus GO:0034504 136 0.039
regulation of mitotic cell cycle phase transition GO:1901990 118 0.038
histone modification GO:0016570 251 0.038
histone acetylation GO:0016573 93 0.036
organonitrogen compound biosynthetic process GO:1901566 200 0.035
cellular response to radiation GO:0071478 65 0.035
oocyte development GO:0048599 1 0.035
rna interference GO:0016246 4 0.035
dna conformation change GO:0071103 113 0.035
segmentation GO:0035282 4 0.034
cellular lipid metabolic process GO:0044255 303 0.034
regulation of cellular response to stress GO:0080135 244 0.034
dna geometric change GO:0032392 32 0.033
glycerophospholipid metabolic process GO:0006650 84 0.032
posttranscriptional regulation of gene expression GO:0010608 213 0.032
single organism reproductive process GO:0044702 98 0.032
single organism carbohydrate metabolic process GO:0044723 193 0.032
regulation of protein localization to nucleus GO:1900180 85 0.032
cellular response to endogenous stimulus GO:0071495 336 0.031
regulation of actin filament based process GO:0032970 141 0.031
double strand break repair via single strand annealing GO:0045002 4 0.031
maintenance of location GO:0051235 112 0.031
cellular protein complex assembly GO:0043623 188 0.030
telomere maintenance via recombination GO:0000722 4 0.030
nuclear division GO:0000280 128 0.030
endocytosis GO:0006897 159 0.029
purine ribonucleoside catabolic process GO:0046130 398 0.029
lipid biosynthetic process GO:0008610 177 0.028
response to hormone GO:0009725 175 0.028
aging GO:0007568 66 0.027
Worm
positive regulation of response to dna damage stimulus GO:2001022 43 0.027
mitotic cell cycle checkpoint GO:0007093 68 0.027
carbohydrate metabolic process GO:0005975 207 0.027
nucleoside triphosphate metabolic process GO:0009141 422 0.027
oxidation reduction process GO:0055114 396 0.027
nucleotide catabolic process GO:0009166 408 0.027
cellular response to growth factor stimulus GO:0071363 197 0.026
organelle assembly GO:0070925 176 0.026
centrosome organization GO:0051297 58 0.026
leukocyte activation GO:0045321 164 0.026
embryo development ending in birth or egg hatching GO:0009792 34 0.026
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
response to steroid hormone GO:0048545 80 0.026
reproduction GO:0000003 63 0.026
cell projection morphogenesis GO:0048858 129 0.026
regulation of protein transport GO:0051223 213 0.025
phosphatidylinositol metabolic process GO:0046488 53 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
organophosphate biosynthetic process GO:0090407 163 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
cell development GO:0048468 328 0.025
organophosphate catabolic process GO:0046434 430 0.025
regulation of cell cycle phase transition GO:1901987 126 0.025
chromosome segregation GO:0007059 114 0.024
purine nucleoside triphosphate metabolic process GO:0009144 412 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
developmental process involved in reproduction GO:0003006 66 0.024
purine nucleotide catabolic process GO:0006195 405 0.024
purine nucleoside catabolic process GO:0006152 398 0.024
signal transduction in response to dna damage GO:0042770 57 0.023
nervous system development GO:0007399 293 0.023
regulation of cytoskeleton organization GO:0051493 177 0.023
regulation of cellular component movement GO:0051270 334 0.023
atp dependent chromatin remodeling GO:0043044 25 0.023
regulation of binding GO:0051098 111 0.023
meiosis i GO:0007127 4 0.023
purine nucleoside monophosphate catabolic process GO:0009128 158 0.023
reproductive process GO:0022414 106 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.022
positive regulation of immunoglobulin mediated immune response GO:0002891 4 0.022
head development GO:0060322 108 0.022
regulation of cell division GO:0051302 116 0.022
double strand break repair via homologous recombination GO:0000724 50 0.022
primary mirna processing GO:0031053 3 0.022
reciprocal dna recombination GO:0035825 4 0.021
regulation of g2 m transition of mitotic cell cycle GO:0010389 20 0.021
response to growth factor GO:0070848 205 0.021
protein alkylation GO:0008213 74 0.021
lipid modification GO:0030258 84 0.021
generation of precursor metabolites and energy GO:0006091 68 0.020
ncrna processing GO:0034470 83 0.020
histone methylation GO:0016571 60 0.020
regulation of heart growth GO:0060420 4 0.020
cell projection organization GO:0030030 252 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.020
histone lysine methylation GO:0034968 50 0.020
glycerolipid metabolic process GO:0046486 107 0.020
maintenance of location in cell GO:0051651 62 0.019
macromolecule methylation GO:0043414 97 0.019
single organism cellular localization GO:1902580 332 0.019
regulation of gene expression epigenetic GO:0040029 73 0.019
posttranscriptional gene silencing GO:0016441 25 0.019
isotype switching GO:0045190 3 0.019
negative regulation of mitotic cell cycle GO:0045930 102 0.019
telomere maintenance GO:0000723 32 0.019
regulation of mitotic cell cycle GO:0007346 189 0.019
myosin filament assembly GO:0031034 2 0.018
gene silencing by mirna GO:0035195 23 0.018
peptidyl lysine acetylation GO:0018394 101 0.018
mitotic sister chromatid segregation GO:0000070 53 0.018
gene silencing by rna GO:0031047 26 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
immune response GO:0006955 307 0.018
signal transduction involved in mitotic g1 dna damage checkpoint GO:0072431 10 0.017
methylation GO:0032259 106 0.017
cellular response to light stimulus GO:0071482 34 0.017
developmental programmed cell death GO:0010623 3 0.017
protein import into nucleus GO:0006606 104 0.017
tissue morphogenesis GO:0048729 96 0.017
chemotaxis GO:0006935 157 0.017
cytokinesis GO:0000910 96 0.017
establishment of protein localization to organelle GO:0072594 172 0.017
regulation of cellular component biogenesis GO:0044087 281 0.017
nucleocytoplasmic transport GO:0006913 176 0.016
regulation of growth GO:0040008 165 0.016
lymphocyte activation GO:0046649 133 0.016
g2 dna damage checkpoint GO:0031572 26 0.016
ribonucleoprotein complex biogenesis GO:0022613 116 0.016
response to nitrogen compound GO:1901698 184 0.016
single organism nuclear import GO:1902593 104 0.016
regulation of transcription factor import into nucleus GO:0042990 39 0.016
gonad development GO:0008406 34 0.016
negative regulation of cell death GO:0060548 345 0.015
cellular response to lipid GO:0071396 127 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
microtubule organizing center organization GO:0031023 62 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
posttranscriptional gene silencing by rna GO:0035194 25 0.015
box c d snornp assembly GO:0000492 3 0.015
engulfment of apoptotic cell GO:0043652 2 0.015
regulation of small gtpase mediated signal transduction GO:0051056 156 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
negative regulation of protein modification process GO:0031400 200 0.015
regulation of cell cycle GO:0051726 393 0.015
regulation of cell morphogenesis GO:0022604 153 0.015
cell cell signaling GO:0007267 155 0.014
response to light stimulus GO:0009416 87 0.014
central nervous system development GO:0007417 123 0.014
regulation of cytoplasmic transport GO:1903649 149 0.014
purine nucleotide biosynthetic process GO:0006164 84 0.014
mitotic nuclear division GO:0007067 119 0.014
protein glycosylation GO:0006486 62 0.014
positive regulation of signal transduction by p53 class mediator GO:1901798 10 0.014
somitogenesis GO:0001756 2 0.014
signal transduction involved in cell cycle checkpoint GO:0072395 16 0.014
negative regulation of dna metabolic process GO:0051053 57 0.014
response to gamma radiation GO:0010332 14 0.014
membrane organization GO:0061024 292 0.014
regulation of nuclear division GO:0051783 65 0.014
non recombinational repair GO:0000726 14 0.014
rna splicing GO:0008380 131 0.014
regulation of cell growth GO:0001558 135 0.014
glucose metabolic process GO:0006006 45 0.014
ribose phosphate biosynthetic process GO:0046390 82 0.013
protein acylation GO:0043543 138 0.013
rna processing GO:0006396 255 0.013
cellular response to external stimulus GO:0071496 111 0.013
negative regulation of phosphorus metabolic process GO:0010563 267 0.013
cell projection assembly GO:0030031 126 0.013
hindbrain development GO:0030902 3 0.013
striated muscle myosin thick filament assembly GO:0071688 2 0.013
attachment of mitotic spindle microtubules to kinetochore GO:0051315 3 0.013
nuclear transport GO:0051169 179 0.013
oocyte differentiation GO:0009994 2 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
mitotic dna integrity checkpoint GO:0044774 30 0.013
regulation of dna methylation GO:0044030 2 0.013
mitotic g1 dna damage checkpoint GO:0031571 17 0.013
alpha amino acid metabolic process GO:1901605 72 0.013
immune system development GO:0002520 195 0.012
response to lipid GO:0033993 206 0.012
purine nucleoside triphosphate catabolic process GO:0009146 392 0.012
positive regulation of developmental process GO:0051094 314 0.012
lens development in camera type eye GO:0002088 2 0.012
endomembrane system organization GO:0010256 196 0.012
organelle localization GO:0051640 84 0.012
peptidyl tyrosine phosphorylation GO:0018108 170 0.012
negative regulation of dna replication GO:0008156 29 0.012
brain development GO:0007420 97 0.012
maintenance of protein location in cell GO:0032507 56 0.012
positive regulation of immune system process GO:0002684 283 0.012
response to purine containing compound GO:0014074 40 0.012
transcription from rna polymerase iii promoter GO:0006383 19 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.012
membrane lipid metabolic process GO:0006643 53 0.012
protein targeting GO:0006605 187 0.012
regulation of immune response GO:0050776 201 0.012
sister chromatid segregation GO:0000819 54 0.012
taxis GO:0042330 157 0.012
regulation of estrogen receptor binding GO:0071898 3 0.012
response to external biotic stimulus GO:0043207 261 0.012
response to inorganic substance GO:0010035 127 0.012
regulation of anatomical structure morphogenesis GO:0022603 286 0.011
neuromuscular junction development GO:0007528 3 0.011
chromosome condensation GO:0030261 15 0.011
purine ribonucleotide catabolic process GO:0009154 404 0.011
response to organonitrogen compound GO:0010243 156 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
monosaccharide metabolic process GO:0005996 74 0.011
cellular amide metabolic process GO:0043603 69 0.011
regulation of intracellular transport GO:0032386 195 0.011
regulation of lymphocyte activation GO:0051249 103 0.011
dna packaging GO:0006323 77 0.011
regulation of translation GO:0006417 89 0.011
response to biotic stimulus GO:0009607 276 0.011
dna replication GO:0006260 116 0.011
positive regulation of rho protein signal transduction GO:0035025 4 0.011
hexose metabolic process GO:0019318 55 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
atp catabolic process GO:0006200 157 0.011
positive regulation of transport GO:0051050 336 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of cell motility GO:2000145 299 0.011
regulation of locomotion GO:0040012 329 0.011
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.011
nuclear import GO:0051170 106 0.011
neuron development GO:0048666 113 0.011
negative regulation of phosphate metabolic process GO:0045936 267 0.011
apoptotic signaling pathway GO:0097190 268 0.011
regulation of viral process GO:0050792 103 0.011
gene silencing GO:0016458 49 0.011
regulation of carbohydrate metabolic process GO:0006109 54 0.011
chemical homeostasis GO:0048878 306 0.011
negative regulation of cell proliferation GO:0008285 228 0.010
microtubule anchoring GO:0034453 24 0.010
negative regulation of intracellular signal transduction GO:1902532 183 0.010
motile cilium assembly GO:0044458 5 0.010
signal transduction by p53 class mediator GO:0072331 72 0.010

TTI1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.023
disease of cellular proliferation DOID:14566 174 0.013
inherited metabolic disorder DOID:655 242 0.013
central nervous system disease DOID:331 186 0.011
nervous system disease DOID:863 431 0.011