Homo sapiens

174 known processes

SPI1

spleen focus forming virus (SFFV) proviral integration oncogene spi1

(Aliases: SPI-A,OF,SFPI1,PU.1,SPI-1)

SPI1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to other organism GO:0051707 261 0.767
hemopoiesis GO:0030097 180 0.712
cell activation GO:0001775 213 0.632
Mouse
immune system development GO:0002520 195 0.451
cytokine production GO:0001816 247 0.384
small gtpase mediated signal transduction GO:0007264 78 0.340
negative regulation of multicellular organismal process GO:0051241 317 0.323
Zebrafish
immune response GO:0006955 307 0.321
regulation of cytokine production GO:0001817 232 0.311
regulation of cell differentiation GO:0045595 393 0.288
hematopoietic or lymphoid organ development GO:0048534 186 0.277
response to external biotic stimulus GO:0043207 261 0.271
negative regulation of cellular component organization GO:0051129 235 0.270
purine ribonucleoside catabolic process GO:0046130 398 0.251
defense response GO:0006952 315 0.250
cellular response to cytokine stimulus GO:0071345 181 0.246
positive regulation of cytokine production GO:0001819 167 0.230
leukocyte activation GO:0045321 164 0.230
Mouse
positive regulation of immune system process GO:0002684 283 0.226
positive regulation of hydrolase activity GO:0051345 331 0.210
positive regulation of gtpase activity GO:0043547 166 0.201
cellular amino acid metabolic process GO:0006520 116 0.190
cell development GO:0048468 328 0.187
Zebrafish Mouse
immune response activating signal transduction GO:0002757 90 0.186
response to cytokine GO:0034097 232 0.182
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.182
cellular response to oxygen containing compound GO:1901701 276 0.180
Rat
vesicle mediated transport GO:0016192 371 0.176
regulation of immune response GO:0050776 201 0.175
nucleotide catabolic process GO:0009166 408 0.173
single organism cell adhesion GO:0098602 179 0.171
negative regulation of protein metabolic process GO:0051248 391 0.169
regulation of gtp catabolic process GO:0033124 180 0.167
myeloid leukocyte differentiation GO:0002573 60 0.165
Zebrafish Mouse
ribonucleoside catabolic process GO:0042454 406 0.162
nucleoside phosphate catabolic process GO:1901292 412 0.162
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.158
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.158
cell adhesion GO:0007155 325 0.157
leukocyte differentiation GO:0002521 98 0.155
Zebrafish Mouse
negative regulation of developmental process GO:0051093 247 0.155
Zebrafish Mouse
ribonucleotide catabolic process GO:0009261 405 0.153
interleukin 12 secretion GO:0072610 1 0.151
regulation of gtpase activity GO:0043087 180 0.150
regulation of cellular amino acid metabolic process GO:0006521 6 0.149
nucleoside catabolic process GO:0009164 408 0.149
organophosphate catabolic process GO:0046434 430 0.148
ribonucleoside triphosphate catabolic process GO:0009203 391 0.147
purine nucleoside triphosphate catabolic process GO:0009146 392 0.146
guanosine containing compound catabolic process GO:1901069 239 0.143
positive regulation of immune response GO:0050778 159 0.140
negative regulation of cell differentiation GO:0045596 171 0.139
Zebrafish Mouse
regulation of cell development GO:0060284 161 0.139
response to biotic stimulus GO:0009607 276 0.138
regulation of nucleotide catabolic process GO:0030811 205 0.137
immune effector process GO:0002252 159 0.135
positive regulation of cell proliferation GO:0008284 301 0.132
purine ribonucleotide catabolic process GO:0009154 404 0.130
regulation of anatomical structure morphogenesis GO:0022603 286 0.129
purine nucleotide catabolic process GO:0006195 405 0.127
nucleoside triphosphate catabolic process GO:0009143 394 0.127
nervous system development GO:0007399 293 0.125
regulation of nucleoside metabolic process GO:0009118 209 0.125
regulation of protein transport GO:0051223 213 0.124
cellular ketone metabolic process GO:0042180 80 0.122
cellular response to lipopolysaccharide GO:0071222 57 0.122
regulation of epithelial cell migration GO:0010632 93 0.116
ribonucleoside triphosphate metabolic process GO:0009199 412 0.116
purine nucleoside catabolic process GO:0006152 398 0.115
regulation of cellular ketone metabolic process GO:0010565 50 0.114
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.114
gtp catabolic process GO:0006184 237 0.112
secretion by cell GO:0032940 226 0.112
purine nucleoside triphosphate metabolic process GO:0009144 412 0.108
purine containing compound catabolic process GO:0072523 411 0.107
negative regulation of apoptotic process GO:0043066 316 0.107
myeloid cell differentiation GO:0030099 117 0.106
negative regulation of alpha beta t cell activation GO:0046636 3 0.106
positive regulation of nucleotide catabolic process GO:0030813 185 0.106
negative regulation of cellular amine metabolic process GO:0033239 3 0.105
gtp metabolic process GO:0046039 239 0.104
covalent chromatin modification GO:0016569 254 0.103
response to bacterium GO:0009617 144 0.103
glycosyl compound catabolic process GO:1901658 413 0.102
cellular amine metabolic process GO:0044106 41 0.102
immune response regulating signaling pathway GO:0002764 97 0.102
regulation of leukocyte activation GO:0002694 115 0.102
regulation of cellular amine metabolic process GO:0033238 11 0.102
negative regulation of protein modification process GO:0031400 200 0.099
female gamete generation GO:0007292 2 0.098
regulation of locomotion GO:0040012 329 0.096
guanosine containing compound metabolic process GO:1901068 244 0.095
positive regulation of cellular catabolic process GO:0031331 284 0.094
regulation of myeloid cell differentiation GO:0045637 81 0.091
defense response to virus GO:0051607 71 0.090
lymphocyte activation GO:0046649 133 0.089
Mouse
regulation of defense response GO:0031347 154 0.088
ras protein signal transduction GO:0007265 73 0.088
positive regulation of gtp catabolic process GO:0033126 166 0.086
actin filament based process GO:0030029 224 0.086
positive regulation of catabolic process GO:0009896 310 0.086
protein secretion GO:0009306 98 0.085
biological adhesion GO:0022610 331 0.085
positive regulation of phosphorylation GO:0042327 394 0.084
regulation of leukocyte differentiation GO:1902105 61 0.083
Zebrafish
regulation of protein localization GO:0032880 296 0.082
mapk cascade GO:0000165 288 0.080
response to abiotic stimulus GO:0009628 336 0.080
t cell activation GO:0042110 99 0.080
regulation of gamma delta t cell activation involved in immune response GO:2001191 1 0.080
defense response to other organism GO:0098542 129 0.080
amine metabolic process GO:0009308 44 0.078
regulation of cellular component movement GO:0051270 334 0.078
actin cytoskeleton organization GO:0030036 207 0.078
negative regulation of phosphate metabolic process GO:0045936 267 0.078
regulation of vesicle mediated transport GO:0060627 130 0.076
lipid metabolic process GO:0006629 381 0.075
purine ribonucleoside metabolic process GO:0046128 437 0.073
enzyme linked receptor protein signaling pathway GO:0007167 303 0.073
epithelium migration GO:0090132 119 0.072
regulation of cell activation GO:0050865 125 0.072
single organismal cell cell adhesion GO:0016337 148 0.072
epithelial cell migration GO:0010631 119 0.070
regulation of response to external stimulus GO:0032101 222 0.070
negative regulation of cytokine production GO:0001818 82 0.070
negative regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:2001189 1 0.069
regulation of cell migration GO:0030334 289 0.069
multicellular organismal aging GO:0010259 3 0.069
regulation of cell morphogenesis GO:0022604 153 0.068
response to oxygen containing compound GO:1901700 369 0.068
Rat
oogenesis GO:0048477 2 0.067
regulation of cellular component biogenesis GO:0044087 281 0.067
regulation of t cell activation GO:0050863 77 0.066
regulation of purine nucleotide catabolic process GO:0033121 205 0.066
positive regulation of protein phosphorylation GO:0001934 313 0.066
signal transduction by phosphorylation GO:0023014 297 0.065
response to virus GO:0009615 126 0.065
neuronal action potential GO:0019228 9 0.065
endocytosis GO:0006897 159 0.065
regulation of secretion GO:0051046 194 0.064
regulation of transferase activity GO:0051338 355 0.064
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.064
regulation of nucleotide metabolic process GO:0006140 269 0.064
positive regulation of cell death GO:0010942 263 0.064
single organism cellular localization GO:1902580 332 0.064
positive regulation of interleukin 13 production GO:0032736 4 0.063
leukocyte mediated immunity GO:0002443 59 0.063
regulation of establishment of protein localization GO:0070201 242 0.063
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.062
chromatin modification GO:0016568 298 0.062
positive regulation of nucleotide metabolic process GO:0045981 230 0.062
neuromuscular junction development GO:0007528 3 0.061
post embryonic development GO:0009791 2 0.061
leukocyte activation involved in immune response GO:0002366 30 0.061
regulation of innate immune response GO:0045088 97 0.060
regulation of lymphocyte activation GO:0051249 103 0.060
response to growth factor GO:0070848 205 0.059
cellular response to endogenous stimulus GO:0071495 336 0.058
activation of immune response GO:0002253 114 0.057
rho protein signal transduction GO:0007266 26 0.057
negative regulation of catalytic activity GO:0043086 335 0.056
cardiovascular system development GO:0072358 262 0.056
Mouse
endothelial cell migration GO:0043542 86 0.055
negative regulation of cellular protein metabolic process GO:0032269 353 0.055
negative regulation of phosphorus metabolic process GO:0010563 267 0.055
intracellular protein transport GO:0006886 270 0.054
osteoclast development GO:0036035 2 0.054
fc receptor mediated inhibitory signaling pathway GO:0002774 2 0.054
epithelium development GO:0060429 227 0.053
Mouse
positive regulation of apoptotic process GO:0043065 246 0.053
memory GO:0007613 3 0.053
negative regulation of programmed cell death GO:0043069 321 0.053
innate immune response GO:0045087 178 0.053
actin polymerization or depolymerization GO:0008154 56 0.052
cellular response to abiotic stimulus GO:0071214 117 0.052
determination of adult lifespan GO:0008340 2 0.052
innate immune response activating signal transduction GO:0002758 48 0.052
regulation of osteoclast development GO:2001204 1 0.052
regulation of purine nucleotide metabolic process GO:1900542 264 0.051
regulation of alpha beta t cell activation GO:0046634 13 0.051
ameboidal type cell migration GO:0001667 135 0.051
negative regulation of transport GO:0051051 176 0.051
positive regulation of nucleoside metabolic process GO:0045979 186 0.051
regulation of mapk cascade GO:0043408 262 0.050
regulation of interferon gamma production GO:0032649 36 0.050
generation of neurons GO:0048699 152 0.050
interferon beta production GO:0032608 23 0.050
adaptive immune response GO:0002250 49 0.050
anatomical structure formation involved in morphogenesis GO:0048646 284 0.050
Mouse
cellular response to growth factor stimulus GO:0071363 197 0.050
secretion GO:0046903 254 0.050
regulation of cell cycle GO:0051726 393 0.050
type i interferon production GO:0032606 27 0.050
positive regulation of proteolysis GO:0045862 142 0.049
regulation of interferon beta production GO:0032648 22 0.049
cell projection organization GO:0030030 252 0.049
protein acylation GO:0043543 138 0.048
positive regulation of cellular amine metabolic process GO:0033240 7 0.048
regulation of kinase activity GO:0043549 314 0.047
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.047
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.046
regulation of ras protein signal transduction GO:0046578 155 0.046
negative regulation of intracellular signal transduction GO:1902532 183 0.045
nuclear transport GO:0051169 179 0.045
immune response inhibiting cell surface receptor signaling pathway GO:0002767 4 0.045
negative regulation of cell development GO:0010721 48 0.045
regulation of secretion by cell GO:1903530 177 0.044
regulation of ras gtpase activity GO:0032318 128 0.044
chromatin organization GO:0006325 351 0.044
regulation of protein secretion GO:0050708 86 0.044
peptidyl tyrosine modification GO:0018212 170 0.044
regulation of actin cytoskeleton organization GO:0032956 116 0.043
positive regulation of developmental process GO:0051094 314 0.043
regulation of endocytosis GO:0030100 72 0.043
negative regulation of interferon beta production GO:0032688 4 0.043
associative learning GO:0008306 1 0.043
actin filament organization GO:0007015 128 0.043
positive regulation of innate immune response GO:0045089 79 0.043
negative regulation of cell cycle GO:0045786 193 0.043
regulation of binding GO:0051098 111 0.043
membrane organization GO:0061024 292 0.042
cell activation involved in immune response GO:0002263 30 0.042
negative regulation of cell death GO:0060548 345 0.042
cd8 positive alpha beta t cell activation GO:0036037 3 0.042
cellular macromolecular complex assembly GO:0034622 324 0.041
cellular metal ion homeostasis GO:0006875 146 0.041
positive regulation of defense response GO:0031349 87 0.041
dephosphorylation GO:0016311 209 0.041
positive regulation of lymphocyte activation GO:0051251 73 0.041
neurogenesis GO:0022008 169 0.040
cellular lipid metabolic process GO:0044255 303 0.039
regulation of cell motility GO:2000145 299 0.039
divalent metal ion transport GO:0070838 152 0.039
hindbrain development GO:0030902 3 0.039
neuron differentiation GO:0030182 138 0.039
regulation of small gtpase mediated signal transduction GO:0051056 156 0.039
regulation of actin filament based process GO:0032970 141 0.039
negative regulation of transforming growth factor beta secretion GO:2001202 1 0.038
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.038
regulation of cytokine biosynthetic process GO:0042035 35 0.037
single organism membrane organization GO:0044802 268 0.037
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.037
lymphocyte mediated immunity GO:0002449 48 0.037
positive regulation of cell migration GO:0030335 172 0.037
cell part morphogenesis GO:0032990 137 0.037
positive regulation of interleukin 5 production GO:0032754 3 0.037
erythrocyte differentiation GO:0030218 28 0.037
regulation of dendritic cell apoptotic process GO:2000668 4 0.036
regulation of protein complex assembly GO:0043254 147 0.036
cytokine mediated signaling pathway GO:0019221 109 0.035
protein localization to organelle GO:0033365 280 0.035
pattern recognition receptor signaling pathway GO:0002221 48 0.035
t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell GO:0002291 4 0.035
negative regulation of phagocytosis GO:0050765 4 0.035
positive regulation of cellular component organization GO:0051130 376 0.035
defense response to bacterium GO:0042742 63 0.035
cellular response to lipid GO:0071396 127 0.035
negative regulation of organelle organization GO:0010639 126 0.035
wound healing GO:0042060 115 0.035
growth GO:0040007 202 0.034
positive regulation of interleukin 4 production GO:0032753 3 0.034
activation of innate immune response GO:0002218 55 0.034
cation transport GO:0006812 331 0.034
positive regulation of cell differentiation GO:0045597 211 0.034
regulation of rho gtpase activity GO:0032319 66 0.034
negative regulation of phosphorylation GO:0042326 174 0.033
negative regulation of interleukin 12 secretion GO:2001183 1 0.033
positive regulation of programmed cell death GO:0043068 249 0.033
cytokine biosynthetic process GO:0042089 37 0.033
cell projection morphogenesis GO:0048858 129 0.033
system process GO:0003008 349 0.033
leukocyte proliferation GO:0070661 74 0.033
positive regulation of t cell proliferation GO:0042102 33 0.033
regulation of cd8 positive alpha beta t cell activation GO:2001185 2 0.032
regulation of endothelial cell migration GO:0010594 67 0.032
small molecule biosynthetic process GO:0044283 157 0.032
production of molecular mediator of immune response GO:0002440 37 0.031
regulation of cytoskeleton organization GO:0051493 177 0.031
regulation of immune effector process GO:0002697 91 0.031
positive regulation of protein transport GO:0051222 135 0.031
second messenger mediated signaling GO:0019932 78 0.031
regulation of protein serine threonine kinase activity GO:0071900 179 0.031
positive regulation of lymphocyte proliferation GO:0050671 46 0.031
oocyte differentiation GO:0009994 2 0.031
positive regulation of ras gtpase activity GO:0032320 117 0.031
regulation of intracellular transport GO:0032386 195 0.031
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.031
histone modification GO:0016570 251 0.031
myeloid leukocyte activation GO:0002274 34 0.030
Mouse
cellular response to dna damage stimulus GO:0006974 379 0.030
cellular component morphogenesis GO:0032989 314 0.030
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.030
heterotypic cell cell adhesion GO:0034113 28 0.030
positive regulation of kinase activity GO:0033674 204 0.030
interferon beta secretion GO:0035546 1 0.030
positive regulation of mapk cascade GO:0043410 190 0.030
calcium mediated signaling GO:0019722 44 0.030
actin filament polymerization GO:0030041 45 0.029
serotonin transport GO:0006837 3 0.029
cellular response to molecule of bacterial origin GO:0071219 62 0.029
regulation of protein kinase activity GO:0045859 289 0.029
regulation of interferon beta secretion GO:0035547 1 0.029
oocyte development GO:0048599 1 0.029
outflow tract septum morphogenesis GO:0003148 4 0.029
negative regulation of transferase activity GO:0051348 124 0.029
cell matrix adhesion GO:0007160 85 0.029
regulation of leukocyte proliferation GO:0070663 67 0.029
neuron development GO:0048666 113 0.029
cytoplasmic transport GO:0016482 379 0.029
establishment of protein localization to organelle GO:0072594 172 0.028
regulation of synaptic plasticity GO:0048167 3 0.028
tissue migration GO:0090130 119 0.028
response to molecule of bacterial origin GO:0002237 82 0.028
regulation of regulatory t cell differentiation GO:0045589 4 0.028
nucleocytoplasmic transport GO:0006913 176 0.028
negative regulation of protein phosphorylation GO:0001933 140 0.028
circulatory system development GO:0072359 262 0.027
Mouse
regulation of mononuclear cell proliferation GO:0032944 65 0.027
negative regulation of tumor necrosis factor biosynthetic process GO:0042536 3 0.027
negative regulation of secretion by cell GO:1903531 52 0.027
histone acetylation GO:0016573 93 0.027
negative regulation of cell activation GO:0050866 33 0.026
coagulation GO:0050817 78 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
regulation of nk t cell activation GO:0051133 4 0.026
regulation of chromosome organization GO:0033044 103 0.026
regulation of response to wounding GO:1903034 101 0.026
regulation of interleukin 10 production GO:0032653 16 0.026
negative regulation of locomotion GO:0040013 118 0.025
cell morphogenesis involved in differentiation GO:0000904 144 0.025
intrinsic apoptotic signaling pathway GO:0097193 127 0.025
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.025
positive regulation of cellular component biogenesis GO:0044089 158 0.025
internal protein amino acid acetylation GO:0006475 101 0.025
phospholipid metabolic process GO:0006644 99 0.025
sensory perception of smell GO:0007608 2 0.025
tumor necrosis factor production GO:0032640 43 0.025
regulation of cytoplasmic transport GO:1903649 149 0.025
inflammatory response GO:0006954 79 0.025
regulation of map kinase activity GO:0043405 108 0.025
apoptotic signaling pathway GO:0097190 268 0.025
regulation of type i interferon production GO:0032479 26 0.025
negative regulation of interleukin 10 production GO:0032693 7 0.025
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.025
cell morphogenesis GO:0000902 296 0.024
positive regulation of transport GO:0051050 336 0.024
neurological system process GO:0050877 163 0.024
response to transforming growth factor beta GO:0071559 94 0.024
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.024
regulation of cell projection organization GO:0031344 107 0.024
negative regulation of cytokine production involved in immune response GO:0002719 13 0.024
regulation of myeloid leukocyte differentiation GO:0002761 39 0.024
Zebrafish
regulation of cell adhesion GO:0030155 166 0.024
chemical homeostasis GO:0048878 306 0.024
plasma membrane organization GO:0007009 115 0.024
negative regulation of cell motility GO:2000146 104 0.023
positive regulation of protein complex assembly GO:0031334 86 0.023
regulation of body fluid levels GO:0050878 99 0.023
cytokine secretion GO:0050663 64 0.023
osteoclast differentiation GO:0030316 21 0.023
regulation of cytokine secretion GO:0050707 57 0.023
dendritic cell apoptotic process GO:0097048 4 0.023
neuron projection development GO:0031175 106 0.023
negative regulation of cell migration GO:0030336 102 0.023
positive regulation of t cell activation GO:0050870 54 0.023
phagocytosis GO:0006909 42 0.023
hemostasis GO:0007599 76 0.023
cellular protein complex assembly GO:0043623 188 0.022
regulation of cellular response to stress GO:0080135 244 0.022
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.022
central nervous system development GO:0007417 123 0.022
somatic stem cell maintenance GO:0035019 4 0.022
Mouse
peripheral nervous system development GO:0007422 2 0.022
regulation of cytokine production involved in immune response GO:0002718 22 0.022
positive regulation of stress activated mapk cascade GO:0032874 60 0.022
regulation of growth GO:0040008 165 0.022
negative regulation of immune system process GO:0002683 136 0.022
Zebrafish
response to wounding GO:0009611 168 0.022
cell type specific apoptotic process GO:0097285 125 0.022
positive regulation of map kinase activity GO:0043406 80 0.022
regulation of membrane potential GO:0042391 95 0.021
organic hydroxy compound metabolic process GO:1901615 147 0.021
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.021
divalent inorganic cation homeostasis GO:0072507 136 0.021
regulation of neuron differentiation GO:0045664 70 0.021
divalent inorganic cation transport GO:0072511 158 0.021
regulation of chromatin organization GO:1902275 56 0.021
negative regulation of osteoclast development GO:2001205 1 0.021
regulation of multi organism process GO:0043900 157 0.021
positive regulation of immune effector process GO:0002699 40 0.021
nitrogen compound transport GO:0071705 191 0.021
positive regulation of endothelial cell migration GO:0010595 39 0.021
tube morphogenesis GO:0035239 95 0.021
Mouse
heart development GO:0007507 95 0.020
positive regulation of regulatory t cell differentiation GO:0045591 3 0.020
response to radiation GO:0009314 151 0.020
regulation of proteolysis GO:0030162 293 0.020
regulation of chromatin modification GO:1903308 51 0.020
regulation of calcium ion transport GO:0051924 79 0.020
embryo development GO:0009790 123 0.020
organ morphogenesis GO:0009887 147 0.020
regulation of serotonin secretion GO:0014062 1 0.020
response to lipopolysaccharide GO:0032496 70 0.020
glycerolipid metabolic process GO:0046486 107 0.020
cellular modified amino acid metabolic process GO:0006575 64 0.020
positive regulation of leukocyte activation GO:0002696 80 0.020
interferon gamma production GO:0032609 39 0.020
response to fungus GO:0009620 4 0.020
negative regulation of nervous system development GO:0051961 28 0.020
multicellular organismal homeostasis GO:0048871 67 0.020
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.020
regulation of leukocyte mediated immunity GO:0002703 38 0.020
regulation of lymphocyte proliferation GO:0050670 64 0.020
negative regulation of protein transport GO:0051224 75 0.020
motor neuron axon guidance GO:0008045 2 0.020
leukocyte migration GO:0050900 107 0.019
mast cell activation involved in immune response GO:0002279 4 0.019
lipid biosynthetic process GO:0008610 177 0.019
head development GO:0060322 108 0.019
integrin mediated signaling pathway GO:0007229 32 0.019
reactive oxygen species metabolic process GO:0072593 75 0.019
cellular homeostasis GO:0019725 196 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.019
negative regulation of secretion GO:0051048 58 0.019
cell cycle arrest GO:0007050 71 0.019
cytokine production involved in immune response GO:0002367 27 0.019
metal ion transport GO:0030001 272 0.019
regulation of actin filament length GO:0030832 56 0.019
embryonic hemopoiesis GO:0035162 4 0.019
regulation of epithelial cell proliferation GO:0050678 113 0.019
negative regulation of endocytosis GO:0045806 19 0.019
alcohol metabolic process GO:0006066 114 0.019
b cell activation GO:0042113 33 0.019
protein import GO:0017038 130 0.019
cell projection assembly GO:0030031 126 0.019
mitotic cell cycle process GO:1903047 286 0.019
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.019
regulation of actin polymerization or depolymerization GO:0008064 56 0.018
action potential GO:0001508 34 0.018
negative regulation of interleukin 10 secretion GO:2001180 1 0.018
reactive oxygen species biosynthetic process GO:1903409 4 0.018
regulation of interleukin 10 secretion GO:2001179 4 0.018
negative regulation of protein kinase activity GO:0006469 98 0.018
negative regulation of serotonin secretion GO:0014063 1 0.018
positive regulation of leukocyte proliferation GO:0070665 48 0.018
positive regulation of locomotion GO:0040017 186 0.018
peptidyl lysine acetylation GO:0018394 101 0.018
negative regulation of growth GO:0045926 97 0.018
embryonic morphogenesis GO:0048598 85 0.018
regulation of cellular component size GO:0032535 82 0.018
fat soluble vitamin metabolic process GO:0006775 19 0.018
regulation of gamma delta t cell activation GO:0046643 1 0.018
regulation of anatomical structure size GO:0090066 101 0.018
response to lipid GO:0033993 206 0.018
negative regulation of phagocytosis engulfment GO:0060101 1 0.018
lymphocyte proliferation GO:0046651 70 0.018
cellular response to external stimulus GO:0071496 111 0.018
positive regulation of organelle organization GO:0010638 195 0.018
regulation of nervous system development GO:0051960 88 0.018
protein processing GO:0016485 226 0.017
negative regulation of leukocyte differentiation GO:1902106 24 0.017
Zebrafish
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.017
salivary gland morphogenesis GO:0007435 4 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
calcium ion transport GO:0006816 147 0.017
cation homeostasis GO:0055080 189 0.017
positive regulation of gamma delta t cell activation GO:0046645 1 0.017
regulation of transforming growth factor beta secretion GO:2001201 1 0.017
regulation of intracellular protein transport GO:0033157 123 0.017
cellular response to biotic stimulus GO:0071216 71 0.017
negative regulation of interferon beta secretion GO:0035548 1 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
positive regulation of intracellular protein transport GO:0090316 76 0.017
lymphocyte activation involved in immune response GO:0002285 20 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
toll like receptor signaling pathway GO:0002224 25 0.017
cell cell junction organization GO:0045216 69 0.017
erk1 and erk2 cascade GO:0070371 104 0.016
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.016
protein localization to nucleus GO:0034504 136 0.016
cell cell signaling GO:0007267 155 0.016
blood coagulation GO:0007596 76 0.016
positive regulation of cell motility GO:2000147 177 0.016
regulation of lipid metabolic process GO:0019216 96 0.016
negative regulation of calcium mediated signaling GO:0050849 4 0.016
positive regulation of mononuclear cell proliferation GO:0032946 47 0.016
actin filament bundle assembly GO:0051017 54 0.016
cell growth GO:0016049 160 0.016
mononuclear cell proliferation GO:0032943 71 0.016

SPI1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.058
hematopoietic system disease DOID:74 100 0.039
cancer DOID:162 167 0.036
disease of cellular proliferation DOID:14566 174 0.036
organ system cancer DOID:0050686 164 0.036