Homo sapiens

40 known processes

CARS

cysteinyl-tRNA synthetase

(Aliases: MGC:11246,CARS1,CYSRS)

CARS biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
amino acid activation GO:0043038 12 0.998
trna aminoacylation for protein translation GO:0006418 8 0.992
trna aminoacylation GO:0043039 12 0.696
cellular amino acid metabolic process GO:0006520 116 0.431
post embryonic development GO:0009791 2 0.425
translation GO:0006412 132 0.406
ncrna metabolic process GO:0034660 108 0.296
trna aminoacylation for mitochondrial protein translation GO:0070127 3 0.269
response to nitrogen compound GO:1901698 184 0.259
mitochondrial rna metabolic process GO:0000959 15 0.258
coenzyme metabolic process GO:0006732 65 0.245
one carbon metabolic process GO:0006730 1 0.182
trna metabolic process GO:0006399 35 0.171
mitochondrial translation GO:0032543 17 0.170
oogenesis GO:0048477 2 0.154
patterning of blood vessels GO:0001569 2 0.124
small molecule biosynthetic process GO:0044283 157 0.122
multicellular organismal aging GO:0010259 3 0.121
serine family amino acid metabolic process GO:0009069 12 0.121
cellular response to endogenous stimulus GO:0071495 336 0.105
response to oxygen containing compound GO:1901700 369 0.104
alpha amino acid metabolic process GO:1901605 72 0.102
carbohydrate metabolic process GO:0005975 207 0.102
nucleoside phosphate biosynthetic process GO:1901293 109 0.096
hair cycle GO:0042633 28 0.087
monocarboxylic acid metabolic process GO:0032787 185 0.087
negative regulation of apoptotic process GO:0043066 316 0.077
angiogenesis GO:0001525 147 0.072
mitochondrion organization GO:0007005 156 0.071
female gamete generation GO:0007292 2 0.060
single organism carbohydrate metabolic process GO:0044723 193 0.060
organophosphate biosynthetic process GO:0090407 163 0.059
metencephalon development GO:0022037 2 0.059
response to organonitrogen compound GO:0010243 156 0.057
proline transport GO:0015824 4 0.056
chemical homeostasis GO:0048878 306 0.054
regulation of cellular ketone metabolic process GO:0010565 50 0.053
blood vessel development GO:0001568 172 0.051
rna processing GO:0006396 255 0.051
cellular ketone metabolic process GO:0042180 80 0.050
negative regulation of catalytic activity GO:0043086 335 0.048
blood vessel morphogenesis GO:0048514 162 0.047
regulation of translation GO:0006417 89 0.047
dna templated transcription termination GO:0006353 3 0.047
regulation of kinase activity GO:0043549 314 0.047
organic anion transport GO:0015711 103 0.046
l serine metabolic process GO:0006563 5 0.046
response to endoplasmic reticulum stress GO:0034976 49 0.046
regulation of mitotic cell cycle GO:0007346 189 0.045
regulation of neuron death GO:1901214 56 0.045
response to peptide hormone GO:0043434 61 0.044
monosaccharide metabolic process GO:0005996 74 0.042
purine nucleobase biosynthetic process GO:0009113 3 0.042
embryo development GO:0009790 123 0.041
cellular macromolecule catabolic process GO:0044265 380 0.040
dna repair GO:0006281 198 0.040
determination of adult lifespan GO:0008340 2 0.038
negative regulation of cellular component organization GO:0051129 235 0.038
vasculature development GO:0001944 181 0.038
regulation of anatomical structure morphogenesis GO:0022603 286 0.037
organonitrogen compound biosynthetic process GO:1901566 200 0.037
nucleotide biosynthetic process GO:0009165 109 0.037
negative regulation of phosphate metabolic process GO:0045936 267 0.036
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.036
hindbrain development GO:0030902 3 0.036
vesicle mediated transport GO:0016192 371 0.035
maintenance of location GO:0051235 112 0.035
negative regulation of protein metabolic process GO:0051248 391 0.034
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.033
hexose metabolic process GO:0019318 55 0.032
response to hormone GO:0009725 175 0.032
oxidation reduction process GO:0055114 396 0.032
mapk cascade GO:0000165 288 0.032
regulation of cytokine production GO:0001817 232 0.032
regulation of transferase activity GO:0051338 355 0.031
protein modification by small protein conjugation GO:0032446 342 0.031
carboxylic acid biosynthetic process GO:0046394 97 0.031
regulation of multi organism process GO:0043900 157 0.031
cofactor metabolic process GO:0051186 87 0.030
cellular amino acid catabolic process GO:0009063 31 0.030
negative regulation of cell migration GO:0030336 102 0.030
regulation of cellular response to stress GO:0080135 244 0.030
chloride transmembrane transport GO:1902476 38 0.030
positive regulation of cellular amine metabolic process GO:0033240 7 0.029
cellular chemical homeostasis GO:0055082 180 0.029
ubiquitin dependent protein catabolic process GO:0006511 206 0.029
negative regulation of cell differentiation GO:0045596 171 0.029
cellular amino acid biosynthetic process GO:0008652 30 0.029
cellular protein catabolic process GO:0044257 261 0.029
cardiovascular system development GO:0072358 262 0.029
regulation of locomotion GO:0040012 329 0.028
response to peptide GO:1901652 65 0.028
positive regulation of protein catabolic process GO:0045732 75 0.028
sequestering of metal ion GO:0051238 24 0.028
cytoplasmic transport GO:0016482 379 0.028
secretion GO:0046903 254 0.028
positive regulation of cellular component organization GO:0051130 376 0.028
lipid metabolic process GO:0006629 381 0.028
negative regulation of cell death GO:0060548 345 0.027
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
circulatory system development GO:0072359 262 0.027
response to insulin GO:0032868 45 0.027
pigment biosynthetic process GO:0046148 10 0.027
apoptotic signaling pathway GO:0097190 268 0.026
regulation of proteolysis GO:0030162 293 0.026
negative regulation of phosphorus metabolic process GO:0010563 267 0.026
endocytosis GO:0006897 159 0.026
cytokine production GO:0001816 247 0.025
response to amino acid GO:0043200 14 0.025
signal transduction by phosphorylation GO:0023014 297 0.025
cellular amine metabolic process GO:0044106 41 0.025
protein catabolic process GO:0030163 325 0.025
regulation of protein kinase activity GO:0045859 289 0.024
divalent metal ion transport GO:0070838 152 0.024
amine metabolic process GO:0009308 44 0.024
regulation of cellular amine metabolic process GO:0033238 11 0.024
peptide transport GO:0015833 74 0.024
water soluble vitamin metabolic process GO:0006767 6 0.024
negative regulation of protein modification process GO:0031400 200 0.024
anatomical structure formation involved in morphogenesis GO:0048646 284 0.024
pyruvate metabolic process GO:0006090 26 0.023
positive regulation of transport GO:0051050 336 0.023
positive regulation of cellular catabolic process GO:0031331 284 0.023
regulation of secretion GO:0051046 194 0.023
negative regulation of phosphorylation GO:0042326 174 0.023
fatty acid metabolic process GO:0006631 115 0.022
transmembrane transport GO:0055085 399 0.022
regulation of neuron apoptotic process GO:0043523 35 0.022
regulation of response to external stimulus GO:0032101 222 0.022
cellular response to biotic stimulus GO:0071216 71 0.022
response to sucrose GO:0009744 1 0.022
negative regulation of developmental process GO:0051093 247 0.021
organic acid biosynthetic process GO:0016053 97 0.021
positive regulation of transferase activity GO:0051347 227 0.021
modification dependent macromolecule catabolic process GO:0043632 212 0.021
regulation of cell migration GO:0030334 289 0.021
response to lipid GO:0033993 206 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
hexose transport GO:0008645 30 0.020
cellular response to oxygen containing compound GO:1901701 276 0.020
reproduction GO:0000003 63 0.020
epithelium development GO:0060429 227 0.020
regulation of cellular amino acid metabolic process GO:0006521 6 0.020
cell type specific apoptotic process GO:0097285 125 0.020
hormone transport GO:0009914 68 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
regulation of hormone levels GO:0010817 125 0.020
intrinsic apoptotic signaling pathway GO:0097193 127 0.019
positive regulation of catabolic process GO:0009896 310 0.019
alanine transport GO:0032328 3 0.019
carbohydrate transport GO:0008643 37 0.019
glucose metabolic process GO:0006006 45 0.019
regulation of mapk cascade GO:0043408 262 0.018
negative regulation of locomotion GO:0040013 118 0.018
regulation of secretion by cell GO:1903530 177 0.018
regulation of cellular component movement GO:0051270 334 0.018
nitrogen compound transport GO:0071705 191 0.018
serine family amino acid catabolic process GO:0009071 5 0.018
cytokine biosynthetic process GO:0042089 37 0.018
positive regulation of response to dna damage stimulus GO:2001022 43 0.018
natural killer cell mediated cytotoxicity GO:0042267 23 0.018
dephosphorylation GO:0016311 209 0.018
mitotic cell cycle GO:0000278 326 0.018
cellular amide metabolic process GO:0043603 69 0.018
alpha amino acid biosynthetic process GO:1901607 23 0.018
regulation of lipopolysaccharide mediated signaling pathway GO:0031664 13 0.017
small molecule catabolic process GO:0044282 92 0.017
rho protein signal transduction GO:0007266 26 0.017
regulation of response to oxidative stress GO:1902882 26 0.017
hormone secretion GO:0046879 65 0.017
positive regulation of cell cycle GO:0045787 140 0.017
cellular response to hormone stimulus GO:0032870 125 0.017
cellular lipid metabolic process GO:0044255 303 0.017
regulation of jak stat cascade GO:0046425 44 0.017
carbohydrate biosynthetic process GO:0016051 42 0.017
regulation of cell cycle GO:0051726 393 0.017
cellular response to nitrogen compound GO:1901699 144 0.017
lipid biosynthetic process GO:0008610 177 0.017
single organism cellular localization GO:1902580 332 0.017
positive regulation of dna repair GO:0045739 25 0.017
protein acetylation GO:0006473 116 0.017
positive regulation of secretion GO:0051047 116 0.017
biological adhesion GO:0022610 331 0.017
positive regulation of hydrolase activity GO:0051345 331 0.017
proteasomal protein catabolic process GO:0010498 176 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.017
negative regulation of cytokine production GO:0001818 82 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
system process GO:0003008 349 0.016
memory GO:0007613 3 0.016
hematopoietic or lymphoid organ development GO:0048534 186 0.016
regeneration GO:0031099 4 0.016
response to abiotic stimulus GO:0009628 336 0.016
morphogenesis of a branching epithelium GO:0061138 20 0.016
lymphocyte activation GO:0046649 133 0.016
response to oxidative stress GO:0006979 121 0.016
regulation of protein binding GO:0043393 66 0.016
sequestering of calcium ion GO:0051208 17 0.016
regulation of cell motility GO:2000145 299 0.015
protein tetramerization GO:0051262 47 0.015
calcium ion transport GO:0006816 147 0.015
response to biotic stimulus GO:0009607 276 0.015
response to mechanical stimulus GO:0009612 51 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
cellular response to lipopolysaccharide GO:0071222 57 0.015
regulation of hormone secretion GO:0046883 57 0.015
defense response GO:0006952 315 0.015
regulation of map kinase activity GO:0043405 108 0.015
regulation of vasculature development GO:1901342 97 0.015
negative regulation of programmed cell death GO:0043069 321 0.015
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.015
compound eye development GO:0048749 1 0.015
segmentation GO:0035282 4 0.015
alpha amino acid catabolic process GO:1901606 26 0.015
monocarboxylic acid biosynthetic process GO:0072330 67 0.015
fatty acid biosynthetic process GO:0006633 46 0.015
positive regulation of mitotic cell cycle GO:0045931 60 0.015
immune response GO:0006955 307 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.015
spermatid differentiation GO:0048515 4 0.015
secretion by cell GO:0032940 226 0.015
cellular response to organonitrogen compound GO:0071417 124 0.014
oxaloacetate metabolic process GO:0006107 1 0.014
negative regulation of glycogen metabolic process GO:0070874 4 0.014
negative regulation of cell motility GO:2000146 104 0.014
response to radiation GO:0009314 151 0.014
cellular response to lipid GO:0071396 127 0.014
stress activated protein kinase signaling cascade GO:0031098 94 0.014
negative regulation of organelle organization GO:0010639 126 0.014
head development GO:0060322 108 0.014
cellular response to external stimulus GO:0071496 111 0.014
cell adhesion GO:0007155 325 0.014
syncytium formation by plasma membrane fusion GO:0000768 2 0.014
aspartate family amino acid biosynthetic process GO:0009067 6 0.014
ribonucleoside triphosphate catabolic process GO:0009203 391 0.014
protein ubiquitination GO:0016567 314 0.014
negative regulation of response to external stimulus GO:0032102 83 0.014
regulation of cytokine biosynthetic process GO:0042035 35 0.014
cell development GO:0048468 328 0.014
regulation of cell division GO:0051302 116 0.014
amide transport GO:0042886 76 0.014
leukocyte mediated cytotoxicity GO:0001909 27 0.014
actin filament based process GO:0030029 224 0.014
regulation of synaptic plasticity GO:0048167 3 0.014
lipid catabolic process GO:0016042 84 0.014
response to extracellular stimulus GO:0009991 85 0.014
locomotory behavior GO:0007626 1 0.014
oocyte development GO:0048599 1 0.014
cardiac muscle cell contraction GO:0086003 4 0.014
cation transport GO:0006812 331 0.014
negative regulation of cellular component movement GO:0051271 106 0.013
mrna metabolic process GO:0016071 175 0.013
jnk cascade GO:0007254 80 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
response to external biotic stimulus GO:0043207 261 0.013
positive regulation of secretion by cell GO:1903532 108 0.013
organic hydroxy compound metabolic process GO:1901615 147 0.013
cellular homeostasis GO:0019725 196 0.013
cellular response to cytokine stimulus GO:0071345 181 0.013
positive regulation of immune system process GO:0002684 283 0.013
ribonucleoside catabolic process GO:0042454 406 0.013
negative regulation of protein kinase activity GO:0006469 98 0.013
amide biosynthetic process GO:0043604 15 0.013
ion transmembrane transport GO:0034220 338 0.013
cellular protein complex assembly GO:0043623 188 0.013
ras protein signal transduction GO:0007265 73 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
organic cation transport GO:0015695 13 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
internal protein amino acid acetylation GO:0006475 101 0.013
cell division GO:0051301 168 0.013
protein maturation GO:0051604 233 0.013
response to organic cyclic compound GO:0014070 204 0.013
myeloid cell differentiation GO:0030099 117 0.013
cell activation GO:0001775 213 0.013
protein oligomerization GO:0051259 173 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
cellular carbohydrate metabolic process GO:0044262 84 0.013
response to molecule of bacterial origin GO:0002237 82 0.013
nadh metabolic process GO:0006734 1 0.013
small gtpase mediated signal transduction GO:0007264 78 0.013
muscle cell proliferation GO:0033002 35 0.013
blood vessel maturation GO:0001955 1 0.012
response to fungus GO:0009620 4 0.012
purine nucleoside triphosphate metabolic process GO:0009144 412 0.012
negative regulation of cell cycle process GO:0010948 121 0.012
central nervous system development GO:0007417 123 0.012
negative regulation of transferase activity GO:0051348 124 0.012
innate immune response GO:0045087 178 0.012
positive regulation of cell death GO:0010942 263 0.012
stress activated mapk cascade GO:0051403 93 0.012
cation transmembrane transport GO:0098655 238 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
cellular divalent inorganic cation homeostasis GO:0072503 128 0.012
positive regulation of synaptic transmission GO:0050806 4 0.012
spermatid development GO:0007286 4 0.012
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.012
positive regulation of cytokine production GO:0001819 167 0.012
regulation of actin filament based process GO:0032970 141 0.012
nucleobase biosynthetic process GO:0046112 4 0.012
actin filament based movement GO:0030048 17 0.012
regulation of binding GO:0051098 111 0.012
cell cycle phase transition GO:0044770 173 0.012
metal ion transport GO:0030001 272 0.012
single organism cell adhesion GO:0098602 179 0.012
negative regulation of cellular amine metabolic process GO:0033239 3 0.012
monosaccharide transport GO:0015749 32 0.012
negative regulation of lipid metabolic process GO:0045833 38 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
nucleotide catabolic process GO:0009166 408 0.012
lipid modification GO:0030258 84 0.012
determination of dorsal ventral asymmetry GO:0048262 4 0.012
cellular glucose homeostasis GO:0001678 11 0.012
canonical wnt signaling pathway GO:0060070 116 0.012
nervous system development GO:0007399 293 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.012
tripartite regional subdivision GO:0007351 2 0.012
negative regulation of smooth muscle cell migration GO:0014912 7 0.011
negative regulation of multi organism process GO:0043901 92 0.011
insulin secretion GO:0030073 39 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
immune effector process GO:0002252 159 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
regulation of cell development GO:0060284 161 0.011
cell morphogenesis GO:0000902 296 0.011
dicarboxylic acid metabolic process GO:0043648 29 0.011
organophosphate catabolic process GO:0046434 430 0.011
regulation of cellular protein catabolic process GO:1903362 96 0.011
regulation of reactive oxygen species metabolic process GO:2000377 41 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
positive regulation of phosphorylation GO:0042327 394 0.011
regulation of lipid metabolic process GO:0019216 96 0.011
actin mediated cell contraction GO:0070252 12 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
organic acid transport GO:0015849 65 0.011
adult locomotory behavior GO:0008344 1 0.011
single organism membrane organization GO:0044802 268 0.011
response to starvation GO:0042594 59 0.011
cellular response to starvation GO:0009267 58 0.011
cell death in response to oxidative stress GO:0036473 29 0.011
leukocyte activation GO:0045321 164 0.011
cytokine metabolic process GO:0042107 38 0.011
nucleoside triphosphate metabolic process GO:0009141 422 0.011
regulation of lipid biosynthetic process GO:0046890 47 0.011
tissue morphogenesis GO:0048729 96 0.011
negative regulation of protein maturation GO:1903318 142 0.011
positive regulation of kinase activity GO:0033674 204 0.011
regulation of angiogenesis GO:0045765 92 0.011
regulation of protein ubiquitination GO:0031396 95 0.011
regulation of cell differentiation GO:0045595 393 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
regulation of actin cytoskeleton organization GO:0032956 116 0.011
cellular ion homeostasis GO:0006873 168 0.011
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.011
meiosis i GO:0007127 4 0.011
positive regulation of transcription from rna polymerase ii promoter in response to oxidative stress GO:0036091 3 0.011
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 2 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
response to decreased oxygen levels GO:0036293 96 0.011
regulation of cell cycle phase transition GO:1901987 126 0.011
regulation of carbohydrate metabolic process GO:0006109 54 0.011
oocyte differentiation GO:0009994 2 0.011
organelle fission GO:0048285 149 0.011
glycosyl compound catabolic process GO:1901658 413 0.010
negative regulation of kinase activity GO:0033673 106 0.010
regulation of cellular component biogenesis GO:0044087 281 0.010
regulation of cellular response to oxidative stress GO:1900407 26 0.010
cellular response to dna damage stimulus GO:0006974 379 0.010
blastoderm segmentation GO:0007350 2 0.010
glucose transport GO:0015758 30 0.010
positive regulation of protein complex assembly GO:0031334 86 0.010
regulation of peptide hormone secretion GO:0090276 41 0.010
response to disaccharide GO:0034285 1 0.010
carbohydrate derivative biosynthetic process GO:1901137 207 0.010
positive regulation of protein ubiquitination GO:0031398 53 0.010
positive regulation of protein modification by small protein conjugation or removal GO:1903322 61 0.010
protein homooligomerization GO:0051260 100 0.010
membrane organization GO:0061024 292 0.010
er nucleus signaling pathway GO:0006984 23 0.010
sulfur amino acid transport GO:0000101 2 0.010
l alanine transport GO:0015808 3 0.010
endosomal transport GO:0016197 129 0.010
regulation of oxidative stress induced cell death GO:1903201 24 0.010
organ formation GO:0048645 3 0.010
posttranscriptional regulation of gene expression GO:0010608 213 0.010
regulation of peptide transport GO:0090087 62 0.010
protein processing GO:0016485 226 0.010
neurological system process GO:0050877 163 0.010
positive regulation of proteolysis GO:0045862 142 0.010
response to hypoxia GO:0001666 96 0.010
methylation GO:0032259 106 0.010
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.010
regulation of ligase activity GO:0051340 29 0.010
protein ubiquitination involved in ubiquitin dependent protein catabolic process GO:0042787 37 0.010
regulation of purine nucleotide metabolic process GO:1900542 264 0.010
oxidoreduction coenzyme metabolic process GO:0006733 19 0.010

CARS disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.895
neuropathy DOID:870 52 0.895
neuromuscular disease DOID:440 38 0.707
central nervous system disease DOID:331 186 0.321
charcot marie tooth disease DOID:10595 33 0.199
motor neuron disease DOID:231 27 0.037
distal hereditary motor neuropathy DOID:0050582 5 0.037
motor neuritis DOID:683 5 0.037
neurodegenerative disease DOID:1289 102 0.037
disease of metabolism DOID:0014667 295 0.025
inherited metabolic disorder DOID:655 242 0.025
amino acid metabolic disorder DOID:9252 50 0.019
charcot marie tooth disease type 2 DOID:0050539 15 0.017
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
organ system cancer DOID:0050686 164 0.013
sensory system disease DOID:0050155 203 0.012
musculoskeletal system disease DOID:17 223 0.012
eye and adnexa disease DOID:1492 150 0.011
eye disease DOID:5614 149 0.011