|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
1.000
|
Mouse |
|
|
negative regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0071930 |
2 |
1.000
|
Mouse |
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
1.000
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
1.000
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
1.000
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
1.000
|
|
|
|
dna damage checkpoint
|
GO:0000077 |
68 |
1.000
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
1.000
|
|
|
|
tube development
|
GO:0035295 |
125 |
1.000
|
Mouse Worm |
|
|
mitotic dna integrity checkpoint
|
GO:0044774 |
30 |
1.000
|
|
|
|
mitotic dna damage checkpoint
|
GO:0044773 |
28 |
1.000
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
1.000
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
1.000
|
Mouse |
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
1.000
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
1.000
|
|
|
|
histone modification
|
GO:0016570 |
251 |
1.000
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
1.000
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
1.000
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
1.000
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
1.000
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
1.000
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
1.000
|
Rat |
|
|
negative regulation of g1 s transition of mitotic cell cycle
|
GO:2000134 |
29 |
1.000
|
Mouse |
|
|
negative regulation of cell cycle g1 s phase transition
|
GO:1902807 |
29 |
1.000
|
Mouse |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
1.000
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
1.000
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
1.000
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.999
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.999
|
Worm |
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.999
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.999
|
|
|
|
urogenital system development
|
GO:0001655 |
65 |
0.999
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.999
|
Mouse |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.999
|
|
|
|
negative regulation of cell cycle phase transition
|
GO:1901988 |
89 |
0.999
|
Mouse |
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.999
|
Mouse Rat |
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.999
|
Mouse |
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.999
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.999
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.999
|
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.998
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.998
|
|
|
|
regulation of cell cycle g1 s phase transition
|
GO:1902806 |
42 |
0.998
|
Mouse |
|
|
g2 dna damage checkpoint
|
GO:0031572 |
26 |
0.998
|
|
|
|
positive regulation of mitotic cell cycle
|
GO:0045931 |
60 |
0.998
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.998
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.997
|
Mouse |
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.997
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.997
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.997
|
Worm |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.997
|
Mouse |
|
|
cell cycle arrest
|
GO:0007050 |
71 |
0.997
|
Mouse Worm |
|
|
sister chromatid cohesion
|
GO:0007062 |
24 |
0.997
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.996
|
Rat |
|
|
cell development
|
GO:0048468 |
328 |
0.996
|
Mouse |
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.996
|
Mouse Worm |
|
|
signal transduction involved in mitotic cell cycle checkpoint
|
GO:0072413 |
13 |
0.995
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.995
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.995
|
|
|
|
intrinsic apoptotic signaling pathway in response to dna damage
|
GO:0008630 |
50 |
0.995
|
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.995
|
Mouse |
|
|
cohesin localization to chromatin
|
GO:0071921 |
4 |
0.995
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.995
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.995
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.995
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.994
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.994
|
|
|
|
regulation of cell cycle arrest
|
GO:0071156 |
36 |
0.994
|
|
|
|
activation of cysteine type endopeptidase activity
|
GO:0097202 |
57 |
0.994
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.993
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.993
|
|
|
|
positive regulation of cell cycle arrest
|
GO:0071158 |
23 |
0.993
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.992
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.992
|
|
|
|
g2 m transition of mitotic cell cycle
|
GO:0000086 |
41 |
0.991
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.991
|
Mouse |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.991
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.991
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.991
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.990
|
Worm |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.990
|
Rat |
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.990
|
Mouse |
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.990
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.990
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.989
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.988
|
|
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.987
|
|
|
|
muscle structure development
|
GO:0061061 |
98 |
0.986
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.985
|
Mouse |
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.984
|
|
|
|
chromatin silencing
|
GO:0006342 |
12 |
0.984
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.982
|
|
|
|
positive regulation of chromosome organization
|
GO:2001252 |
41 |
0.982
|
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.981
|
|
|
|
regulation of g1 s transition of mitotic cell cycle
|
GO:2000045 |
40 |
0.980
|
Mouse |
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.980
|
|
|
|
dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest
|
GO:0006977 |
9 |
0.979
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.979
|
|
|
|
cell cycle g2 m phase transition
|
GO:0044839 |
43 |
0.977
|
|
|
|
myoblast differentiation
|
GO:0045445 |
21 |
0.976
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.975
|
Mouse |
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.974
|
|
|
|
mitotic g1 dna damage checkpoint
|
GO:0031571 |
17 |
0.973
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.973
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.972
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.972
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.971
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.971
|
|
|
|
histone h3 k9 modification
|
GO:0061647 |
11 |
0.970
|
|
|
|
mitotic sister chromatid segregation
|
GO:0000070 |
53 |
0.969
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.969
|
Mouse |
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.968
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.967
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.967
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.967
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.966
|
|
|
|
intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:0072332 |
37 |
0.964
|
|
|
|
cell cycle g1 s phase transition
|
GO:0044843 |
80 |
0.964
|
Mouse |
|
|
intracellular signal transduction involved in g1 dna damage checkpoint
|
GO:1902400 |
10 |
0.964
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.963
|
|
|
|
rna stabilization
|
GO:0043489 |
18 |
0.963
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.962
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.961
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.960
|
|
|
|
mitotic g1 s transition checkpoint
|
GO:0044819 |
17 |
0.960
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.959
|
|
|
|
regulation of transcription involved in g1 s transition of mitotic cell cycle
|
GO:0000083 |
8 |
0.955
|
Mouse |
|
|
oogenesis
|
GO:0048477 |
2 |
0.954
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.953
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.953
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.952
|
|
|
|
attachment of spindle microtubules to kinetochore
|
GO:0008608 |
17 |
0.952
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.952
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.952
|
|
|
|
dna replication
|
GO:0006260 |
116 |
0.952
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.951
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.950
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.950
|
Worm |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.950
|
|
|
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
79 |
0.948
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.947
|
Mouse Worm |
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.945
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.943
|
|
|
|
meiotic nuclear division
|
GO:0007126 |
10 |
0.943
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.943
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.941
|
|
|
|
positive regulation of fibroblast proliferation
|
GO:0048146 |
21 |
0.941
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.939
|
Worm |
|
|
protein deacylation
|
GO:0035601 |
39 |
0.939
|
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
49 |
0.938
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.933
|
|
|
|
kidney development
|
GO:0001822 |
53 |
0.932
|
|
|
|
regulation of fibroblast proliferation
|
GO:0048145 |
32 |
0.932
|
|
|
|
regulation of sister chromatid cohesion
|
GO:0007063 |
9 |
0.932
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.931
|
Worm |
|
|
regulation of sister chromatid segregation
|
GO:0033045 |
27 |
0.930
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.930
|
Mouse |
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.928
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.928
|
Mouse Worm |
|
|
signal transduction by p53 class mediator
|
GO:0072331 |
72 |
0.926
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.926
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.925
|
Worm |
|
|
neuron development
|
GO:0048666 |
113 |
0.924
|
Mouse |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.921
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.918
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.916
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.915
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.914
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.914
|
|
|
|
positive regulation of cellular protein catabolic process
|
GO:1903364 |
37 |
0.911
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.911
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.905
|
|
|
|
positive regulation of chromosome segregation
|
GO:0051984 |
9 |
0.902
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.897
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.896
|
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
35 |
0.894
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.890
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.890
|
|
|
|
regulation of mitotic sister chromatid separation
|
GO:0010965 |
27 |
0.890
|
|
|
|
regulation of signal transduction by p53 class mediator
|
GO:1901796 |
26 |
0.882
|
|
|
|
regulation of mitotic metaphase anaphase transition
|
GO:0030071 |
26 |
0.880
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.879
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.878
|
|
|
|
histone methylation
|
GO:0016571 |
60 |
0.877
|
|
|
|
chromosome separation
|
GO:0051304 |
23 |
0.871
|
|
|
|
regulation of g2 m transition of mitotic cell cycle
|
GO:0010389 |
20 |
0.871
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.869
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.865
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.861
|
|
|
|
zymogen activation
|
GO:0031638 |
70 |
0.857
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.856
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.856
|
|
|
|
signal transduction involved in mitotic dna integrity checkpoint
|
GO:1902403 |
13 |
0.853
|
|
|
|
regulation of chromosome segregation
|
GO:0051983 |
44 |
0.850
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.849
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.849
|
|
|
|
regulation of cohesin localization to chromatin
|
GO:0071922 |
4 |
0.846
|
|
|
|
signal transduction involved in mitotic g1 dna damage checkpoint
|
GO:0072431 |
10 |
0.846
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.841
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.839
|
|
|
|
regulation of mitotic sister chromatid segregation
|
GO:0033047 |
27 |
0.835
|
|
|
|
regulation of chromatin modification
|
GO:1903308 |
51 |
0.826
|
|
|
|
type b pancreatic cell development
|
GO:0003323 |
4 |
0.824
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.821
|
|
|
|
maintenance of mitotic sister chromatid cohesion
|
GO:0034088 |
6 |
0.814
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.810
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.810
|
|
|
|
glycoprotein biosynthetic process
|
GO:0009101 |
91 |
0.806
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.804
|
Mouse |
|
|
pattern specification process
|
GO:0007389 |
43 |
0.798
|
|
|
|
response to purine containing compound
|
GO:0014074 |
40 |
0.796
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.795
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.791
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.790
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.789
|
|
|
|
regulation of transcription involved in g2 m transition of mitotic cell cycle
|
GO:0000117 |
1 |
0.787
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.781
|
|
|
|
eye development
|
GO:0001654 |
42 |
0.779
|
|
|
|
reproduction
|
GO:0000003 |
63 |
0.778
|
Worm |
|
|
mitotic g2 dna damage checkpoint
|
GO:0007095 |
7 |
0.776
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.775
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.775
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.773
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.767
|
|
|
|
protein deacetylation
|
GO:0006476 |
38 |
0.764
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.762
|
|
|
|
chromatin remodeling
|
GO:0006338 |
55 |
0.758
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.749
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.747
|
|
|
|
epithelial cell development
|
GO:0002064 |
34 |
0.746
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.744
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.739
|
|
|
|
regulation of metaphase anaphase transition of cell cycle
|
GO:1902099 |
26 |
0.738
|
|
|
|
signal transduction involved in cell cycle checkpoint
|
GO:0072395 |
16 |
0.738
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.736
|
|
|
|
renal system development
|
GO:0072001 |
63 |
0.734
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.734
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.726
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.723
|
Worm |
|
|
positive regulation of developmental growth
|
GO:0048639 |
16 |
0.721
|
Worm |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.712
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.708
|
Worm |
|
|
segmentation
|
GO:0035282 |
4 |
0.705
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.702
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.701
|
Worm |
|
|
positive regulation of epithelial cell proliferation
|
GO:0050679 |
65 |
0.700
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.695
|
|
|
|
mitotic g2 m transition checkpoint
|
GO:0044818 |
9 |
0.693
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.691
|
Worm |
|
|
regulation of chromatin organization
|
GO:1902275 |
56 |
0.686
|
|
|
|
microtubule anchoring
|
GO:0034453 |
24 |
0.684
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.684
|
Mouse |
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.679
|
|
|
|
positive regulation of mitotic cell cycle phase transition
|
GO:1901992 |
19 |
0.675
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.671
|
|
|
|
response to toxic substance
|
GO:0009636 |
37 |
0.670
|
|
|
|
g1 dna damage checkpoint
|
GO:0044783 |
18 |
0.670
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.662
|
|
|
|
positive regulation of meiotic cell cycle
|
GO:0051446 |
2 |
0.662
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.654
|
|
|
|
macromolecule methylation
|
GO:0043414 |
97 |
0.650
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.649
|
|
|
|
regulation of leukocyte proliferation
|
GO:0070663 |
67 |
0.648
|
|
|
|
membrane organization
|
GO:0061024 |
292 |
0.647
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.646
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.634
|
Mouse |
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.627
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.624
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.620
|
|
|
|
lymphocyte proliferation
|
GO:0046651 |
70 |
0.618
|
|
|
|
regulation of cell cycle g2 m phase transition
|
GO:1902749 |
22 |
0.612
|
|
|
|
dna damage induced protein phosphorylation
|
GO:0006975 |
5 |
0.611
|
|
|
|
meiotic chromosome segregation
|
GO:0045132 |
4 |
0.606
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.603
|
|
|
|
maintenance of sister chromatid cohesion
|
GO:0034086 |
6 |
0.602
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.602
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.602
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.601
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.599
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.587
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.586
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.584
|
|
|
|
multicellular organismal reproductive process
|
GO:0048609 |
40 |
0.580
|
Worm |
|
|
oocyte development
|
GO:0048599 |
1 |
0.580
|
|
|
|
maintenance of location in cell
|
GO:0051651 |
62 |
0.574
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.571
|
|
|
|
response to temperature stimulus
|
GO:0009266 |
22 |
0.567
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.562
|
|
|
|
regulation of histone modification
|
GO:0031056 |
47 |
0.561
|
|
|
|
maintenance of protein location in cell
|
GO:0032507 |
56 |
0.559
|
|
|
|
regulation of intracellular steroid hormone receptor signaling pathway
|
GO:0033143 |
32 |
0.554
|
|
|
|
negative regulation of dna replication
|
GO:0008156 |
29 |
0.554
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.549
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.547
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.545
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.543
|
Worm |
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.543
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.542
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.533
|
|
|
|
regulation of cell size
|
GO:0008361 |
19 |
0.527
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.525
|
|
|
|
regulation of dna binding
|
GO:0051101 |
37 |
0.523
|
|
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.522
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.520
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.510
|
|
|
|
positive regulation of metaphase anaphase transition of cell cycle
|
GO:1902101 |
6 |
0.493
|
|
|
|
regulation of mrna stability
|
GO:0043488 |
23 |
0.481
|
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
30 |
0.481
|
|
|
|
positive regulation of hormone biosynthetic process
|
GO:0046886 |
4 |
0.480
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.475
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.473
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.471
|
|
|
|
embryonic organ morphogenesis
|
GO:0048562 |
24 |
0.470
|
Worm |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.469
|
|
|
|
methylation
|
GO:0032259 |
106 |
0.468
|
|
|
|
cellular response to nerve growth factor stimulus
|
GO:1990090 |
6 |
0.465
|
|
|
|
regulation of protein modification by small protein conjugation or removal
|
GO:1903320 |
107 |
0.464
|
|
|
|
negative regulation of gene expression epigenetic
|
GO:0045814 |
19 |
0.459
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.458
|
|
|
|
signal transduction involved in dna integrity checkpoint
|
GO:0072401 |
15 |
0.454
|
|
|
|
signal transduction involved in mitotic dna damage checkpoint
|
GO:1902402 |
13 |
0.444
|
|
|
|
mitotic sister chromatid cohesion
|
GO:0007064 |
12 |
0.444
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.439
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.438
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.436
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.433
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.433
|
|
|
|
negative regulation of ras protein signal transduction
|
GO:0046580 |
11 |
0.431
|
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
34 |
0.431
|
Worm |
|
|
actin filament based process
|
GO:0030029 |
224 |
0.430
|
|
|
|
peptidyl tyrosine dephosphorylation
|
GO:0035335 |
36 |
0.429
|
|
|
|
negative regulation of chromatin modification
|
GO:1903309 |
21 |
0.427
|
|
|
|
positive regulation of neuron differentiation
|
GO:0045666 |
40 |
0.425
|
|
|
|
metaphase anaphase transition of cell cycle
|
GO:0044784 |
21 |
0.424
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.422
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.418
|
Mouse |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.417
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.415
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.413
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.404
|
|
|
|
t cell differentiation in thymus
|
GO:0033077 |
4 |
0.403
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.402
|
|
|
|
dna endoreduplication
|
GO:0042023 |
5 |
0.398
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.398
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.394
|
|
|
|
lens development in camera type eye
|
GO:0002088 |
2 |
0.390
|
|
|
|
regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter
|
GO:0072366 |
1 |
0.379
|
|
|
|
protein localization to chromosome
|
GO:0034502 |
30 |
0.378
|
|
|
|
regulation of dendrite development
|
GO:0050773 |
18 |
0.375
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.375
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.373
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.372
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.371
|
|
|
|
methylation dependent chromatin silencing
|
GO:0006346 |
3 |
0.370
|
|
|
|
macromolecule deacylation
|
GO:0098732 |
41 |
0.363
|
|
|
|
dendrite development
|
GO:0016358 |
24 |
0.361
|
|
|
|
cell fate commitment
|
GO:0045165 |
27 |
0.345
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.345
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.344
|
|
|
|
regulation of mitosis
|
GO:0007088 |
63 |
0.339
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.339
|
|
|
|
regulation of dna replication
|
GO:0006275 |
68 |
0.339
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.338
|
|
|
|
signal transduction involved in dna damage checkpoint
|
GO:0072422 |
15 |
0.336
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.334
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.334
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.327
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.326
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.325
|
|
|
|
mrna stabilization
|
GO:0048255 |
18 |
0.323
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.322
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.321
|
|
|
|
protein dna complex assembly
|
GO:0065004 |
64 |
0.319
|
|
|
|
embryonic digestive tract development
|
GO:0048566 |
10 |
0.317
|
Worm |
|
|
positive regulation of cell morphogenesis involved in differentiation
|
GO:0010770 |
50 |
0.316
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.315
|
|
|
|
circadian regulation of gene expression
|
GO:0032922 |
8 |
0.313
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.312
|
|
|
|
positive regulation of transcription initiation from rna polymerase ii promoter
|
GO:0060261 |
4 |
0.309
|
|
|
|
regulation of double strand break repair
|
GO:2000779 |
22 |
0.307
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.304
|
|
|
|
negative regulation of chromatin silencing
|
GO:0031936 |
4 |
0.303
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.301
|
|
|
|
regulation of muscle organ development
|
GO:0048634 |
27 |
0.300
|
|
|
|
regulation of chromatin silencing
|
GO:0031935 |
8 |
0.299
|
|
|
|
negative regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903051 |
35 |
0.299
|
|
|
|
positive regulation of cell cycle phase transition
|
GO:1901989 |
22 |
0.296
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.295
|
|
|
|
positive regulation of cytoskeleton organization
|
GO:0051495 |
83 |
0.294
|
|
|
|
multicellular organism reproduction
|
GO:0032504 |
42 |
0.293
|
Worm |
|
|
regionalization
|
GO:0003002 |
29 |
0.292
|
|
|
|
dna recombination
|
GO:0006310 |
77 |
0.291
|
|
|
|
muscle organ development
|
GO:0007517 |
56 |
0.290
|
Mouse |
|
|
gene silencing
|
GO:0016458 |
49 |
0.284
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.283
|
|
|
|
developmental cell growth
|
GO:0048588 |
18 |
0.280
|
|
|
|
dendrite morphogenesis
|
GO:0048813 |
14 |
0.277
|
|
|
|
t cell differentiation
|
GO:0030217 |
29 |
0.276
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.270
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.270
|
|
|
|
regulation of striated muscle tissue development
|
GO:0016202 |
26 |
0.269
|
|
|
|
dna dependent dna replication
|
GO:0006261 |
44 |
0.268
|
|
|
|
immune response regulating signaling pathway
|
GO:0002764 |
97 |
0.268
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.267
|
|
|
|
negative regulation of proteasomal protein catabolic process
|
GO:1901799 |
32 |
0.266
|
|
|
|
kidney morphogenesis
|
GO:0060993 |
19 |
0.266
|
|
|
|
system process
|
GO:0003008 |
349 |
0.265
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.258
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.252
|
|
|
|
positive regulation of multi organism process
|
GO:0043902 |
56 |
0.251
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.243
|
|
|
|
regulation of dna repair
|
GO:0006282 |
47 |
0.242
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.242
|
|
|
|
positive regulation of histone modification
|
GO:0031058 |
29 |
0.241
|
|
|
|
regulation of transcription by chromatin organization
|
GO:0034401 |
1 |
0.240
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.239
|
|
|
|
centrosome cycle
|
GO:0007098 |
32 |
0.239
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.236
|
|
|
|
negative regulation of histone modification
|
GO:0031057 |
19 |
0.234
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.231
|
|
|
|
mitotic cell cycle arrest
|
GO:0071850 |
4 |
0.231
|
Worm |
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.229
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.227
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.227
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.225
|
Mouse Worm |
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.222
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.221
|
|
|
|
positive regulation of cell cycle g2 m phase transition
|
GO:1902751 |
8 |
0.219
|
|
|
|
positive regulation of chromatin modification
|
GO:1903310 |
30 |
0.214
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.211
|
|
|
|
head development
|
GO:0060322 |
108 |
0.209
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.209
|
|
|
|
response to steroid hormone
|
GO:0048545 |
80 |
0.209
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.204
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.203
|
|
|
|
response to estrogen
|
GO:0043627 |
47 |
0.202
|
|
|
|
male meiosis
|
GO:0007140 |
1 |
0.201
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.200
|
|
|
|
response to nerve growth factor
|
GO:1990089 |
6 |
0.199
|
|
|
|
metaphase plate congression
|
GO:0051310 |
18 |
0.198
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.198
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.197
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.197
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.195
|
|
|
|
positive regulation of dna replication
|
GO:0045740 |
35 |
0.193
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.192
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.188
|
Mouse |
|
|
response to uv
|
GO:0009411 |
73 |
0.187
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.187
|
Mouse |
|
|
cellular response to uv
|
GO:0034644 |
32 |
0.186
|
|
|
|
cartilage development
|
GO:0051216 |
31 |
0.186
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.186
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.184
|
|
|
|
cardiac muscle tissue development
|
GO:0048738 |
39 |
0.184
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.183
|
|
|
|
protein stabilization
|
GO:0050821 |
64 |
0.182
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.181
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.181
|
|
|
|
negative regulation of intrinsic apoptotic signaling pathway
|
GO:2001243 |
40 |
0.178
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.177
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.177
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.177
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.176
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.173
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.173
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.173
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.173
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.172
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.172
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.172
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.171
|
Mouse |
|
|
muscle tissue development
|
GO:0060537 |
62 |
0.169
|
Mouse |
|
|
intracellular steroid hormone receptor signaling pathway
|
GO:0030518 |
61 |
0.168
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.168
|
|
|
|
hair cycle
|
GO:0042633 |
28 |
0.168
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.163
|
|
|
|
positive regulation of cardiac muscle cell proliferation
|
GO:0060045 |
2 |
0.163
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.161
|
|
|
|
regulation of nuclear division
|
GO:0051783 |
65 |
0.161
|
|
|
|
epidermis development
|
GO:0008544 |
59 |
0.160
|
|
|
|
protein destabilization
|
GO:0031648 |
12 |
0.158
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.155
|
|
|
|
positive regulation of g2 m transition of mitotic cell cycle
|
GO:0010971 |
8 |
0.154
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.153
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.151
|
|
