IMP
Process View
regulation of metaphase anaphase transition of cell cycle
Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
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Click on a gene's description to view its network relationships with genes known to be involved in "regulation of metaphase anaphase transition of cell cycle"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.999 | Yeast Fly | |
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.999 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.995 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.994 | Fly | |
| ANAPC7 | anaphase promoting complex subunit 7 | 0.972 | ||
| BUB3 | budding uninhibited by benzimidazoles 3 homolog (yeast) | 0.969 | Worm Fly | |
| CCNA2 | cyclin A2 | 0.954 | ||
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.910 | ||
| ANAPC4 | anaphase promoting complex subunit 4 | 0.896 | ||
| CCNB1 | cyclin B1 | 0.874 | ||
| CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.836 | ||
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.799 | Fly | |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.743 | ||
| RB1 | retinoblastoma 1 | 0.738 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.597 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.568 | ||
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.479 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.444 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.431 | ||
| SMC6 | structural maintenance of chromosomes 6 | 0.405 | ||
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.395 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.387 | ||
| RAD21 | RAD21 homolog (S. pombe) | 0.368 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.305 | ||
| ORC1 | origin recognition complex, subunit 1 | 0.301 | ||
| RBL1 | retinoblastoma-like 1 (p107) | 0.295 | Human | |
| CUL2 | cullin 2 | 0.236 | Worm | |
| CCNE1 | cyclin E1 | 0.231 | Fly | |
| CREBBP | CREB binding protein | 0.213 | ||
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.210 | Worm | |
| NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.210 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.205 | ||
| CUL1 | cullin 1 | 0.194 | ||
| AURKB | aurora kinase B | 0.193 | ||
| CBX5 | chromobox homolog 5 | 0.187 | ||
| CCNB2 | cyclin B2 | 0.158 | ||
| CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.155 | Fly | |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.154 | ||
| COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.146 | ||
| SMC3 | structural maintenance of chromosomes 3 | 0.131 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.131 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.123 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.114 | ||
| TFDP1 | transcription factor Dp-1 | 0.111 | ||
| VHL | von Hippel-Lindau tumor suppressor | 0.103 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.099 | ||
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.091 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.091 | ||
| PLK1 | polo-like kinase 1 | 0.078 | ||
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.075 | ||
| ANAPC1 | anaphase promoting complex subunit 1 | 0.071 | ||
| DOT1L | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.068 | ||
| STAG1 | stromal antigen 1 | 0.065 | ||
| CCND1 | cyclin D1 | 0.064 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.058 | ||
| PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.055 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.055 | ||
| SKA3 | spindle and kinetochore associated complex subunit 3 | 0.053 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.053 | ||
| E2F1 | E2F transcription factor 1 | 0.052 | ||
| RBL2 | retinoblastoma-like 2 (p130) | 0.050 | Human | |
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.049 | ||
| NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.049 | ||
| SPC24 | SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.049 | ||
| TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.048 | ||
| BRCA1 | breast cancer 1, early onset | 0.045 | ||
| FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.045 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.045 | ||
| SMC4 | structural maintenance of chromosomes 4 | 0.044 | ||
| BRCA2 | breast cancer 2, early onset | 0.043 | ||
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.043 | ||
| BIRC5 | baculoviral IAP repeat containing 5 | 0.043 | ||
| CDK1 | cyclin-dependent kinase 1 | 0.043 | ||
| NDC80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.042 | ||
| KIF18A | kinesin family member 18A | 0.041 | ||
| NSMCE4A | non-SMC element 4 homolog A (S. cerevisiae) | 0.040 | ||
| HERC2 | hect domain and RLD 2 | 0.040 | ||
| BTRC | beta-transducin repeat containing | 0.038 | ||
| SKA2 | spindle and kinetochore associated complex subunit 2 | 0.038 | ||
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | 0.037 | ||
| COMMD1 | copper metabolism (Murr1) domain containing 1 | 0.037 | ||
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.037 | ||
| INCENP | inner centromere protein antigens 135/155kDa | 0.036 | ||
| PARP3 | poly (ADP-ribose) polymerase family, member 3 | 0.036 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.036 | ||
| COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.036 | ||
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.035 | ||
| ATMIN | ATM interactor | 0.035 | ||
| SGOL2 | shugoshin-like 2 (S. pombe) | 0.034 | ||
| CASC5 | cancer susceptibility candidate 5 | 0.033 | ||
| LRR1 | leucine rich repeat protein 1 | 0.033 | ||
| TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.032 | Worm | |
| SIRT2 | sirtuin 2 | 0.032 | ||
| PPME1 | protein phosphatase methylesterase 1 | 0.032 | ||
| ANKRD52 | ankyrin repeat domain 52 | 0.032 | ||
| CUL5 | cullin 5 | 0.030 | ||
| PRRC2C | proline-rich coiled-coil 2C | 0.030 | ||
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.030 | ||
| FBXO5 | F-box protein 5 | 0.029 | ||
| RBBP8 | retinoblastoma binding protein 8 | 0.029 | ||
| TCP1 | t-complex 1 | 0.028 | ||
| C13orf27 | chromosome 13 open reading frame 27 | 0.028 | ||
| AXIN2 | axin 2 | 0.028 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.028 | ||
| ORC2 | origin recognition complex, subunit 2 | 0.028 | ||
| E2F4 | E2F transcription factor 4, p107/p130-binding | 0.027 | ||
| PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.027 | ||
| IGF1R | insulin-like growth factor 1 receptor | 0.027 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.027 | ||
| SMAD2 | SMAD family member 2 | 0.026 | ||
| SGOL1 | shugoshin-like 1 (S. pombe) | 0.026 | ||
| ZWINT | ZW10 interactor | 0.025 | ||
| MAK | male germ cell-associated kinase | 0.025 | ||
| DEAF1 | deformed epidermal autoregulatory factor 1 (Drosophila) | 0.025 | ||
| ANAPC5 | anaphase promoting complex subunit 5 | 0.025 | ||
| OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.025 | ||
| E2F5 | E2F transcription factor 5, p130-binding | 0.024 | ||
| MYBL2 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | 0.024 | ||
| ANAPC10 | anaphase promoting complex subunit 10 | 0.024 | Yeast | |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.023 | ||
| NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 0.023 | ||
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.023 | ||
| APC | adenomatous polyposis coli | 0.023 | ||
| NSL1 | NSL1, MIND kinetochore complex component, homolog (S. cerevisiae) | 0.023 | ||
| ZNHIT3 | zinc finger, HIT-type containing 3 | 0.022 | ||
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.022 | ||
| FOXM1 | forkhead box M1 | 0.022 | ||
| CCND3 | cyclin D3 | 0.021 | ||
| PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.020 | ||
| HIST1H4A | histone cluster 1, H4a | 0.020 | ||
| C13orf34 | chromosome 13 open reading frame 34 | 0.020 | ||
| TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.020 | ||
| PTK2 | PTK2 protein tyrosine kinase 2 | 0.020 | ||
| HIST1H1E | histone cluster 1, H1e | 0.020 | ||
| REV3L | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 0.019 | ||
| KDM4A | lysine (K)-specific demethylase 4A | 0.019 | ||
| CCNE2 | cyclin E2 | 0.019 | Fly | |
| CENPJ | centromere protein J | 0.019 | ||
| CUL4A | cullin 4A | 0.019 | ||
| PLK4 | polo-like kinase 4 | 0.019 | ||
| PFDN4 | prefoldin subunit 4 | 0.019 | ||
| LIN54 | lin-54 homolog (C. elegans) | 0.018 | ||
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.018 | ||
| NUF2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.018 | ||
| ANAPC16 | anaphase promoting complex subunit 16 | 0.018 | ||
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.018 | ||
| USP49 | ubiquitin specific peptidase 49 | 0.017 | Human | |
| CDCA8 | cell division cycle associated 8 | 0.017 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.017 | ||
| ZNF207 | zinc finger protein 207 | 0.017 | ||
| RAD51AP1 | RAD51 associated protein 1 | 0.017 | ||
| C19orf39 | chromosome 19 open reading frame 39 | 0.017 | ||
| USP44 | ubiquitin specific peptidase 44 | 0.017 | ||
| NDNL2 | necdin-like 2 | 0.016 | ||
| BCL2L1 | BCL2-like 1 | 0.016 | ||
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.016 | ||
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.016 | ||
| LIN9 | lin-9 homolog (C. elegans) | 0.016 | ||
| BTBD10 | BTB (POZ) domain containing 10 | 0.015 | ||
| GTSE1 | G-2 and S-phase expressed 1 | 0.015 | ||
| CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.015 | ||
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.015 | ||
| EML2 | echinoderm microtubule associated protein like 2 | 0.015 | ||
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.015 | ||
| AXIN1 | axin 1 | 0.015 | ||
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.015 | ||
| CAND1 | cullin-associated and neddylation-dissociated 1 | 0.014 | ||
| SLX4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae) | 0.014 | ||
| TPP2 | tripeptidyl peptidase II | 0.014 | ||
| HIST1H1B | histone cluster 1, H1b | 0.014 | ||
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.014 | ||
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 0.014 | ||
| DEPDC1 | DEP domain containing 1 | 0.014 | ||
| LMNA | lamin A/C | 0.014 | ||
| TPR | translocated promoter region (to activated MET oncogene) | 0.013 | ||
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.013 | ||
| KIF11 | kinesin family member 11 | 0.013 | ||
| HUWE1 | HECT, UBA and WWE domain containing 1 | 0.013 | ||
| TROAP | trophinin associated protein (tastin) | 0.013 | ||
| SERTAD4 | SERTA domain containing 4 | 0.013 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.013 | ||
| SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.013 | ||
| PRNP | prion protein | 0.013 | ||
| MAD2L1BP | MAD2L1 binding protein | 0.013 | ||
| TOP3A | topoisomerase (DNA) III alpha | 0.013 | ||
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.012 | ||
| CCDC101 | coiled-coil domain containing 101 | 0.012 | ||
| HIST1H4F | histone cluster 1, H4f | 0.012 | ||
| RAD51L1 | RAD51-like 1 (S. cerevisiae) | 0.012 | ||
| CENPF | centromere protein F, 350/400kDa (mitosin) | 0.012 | ||
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.012 | ||
| TOP1 | topoisomerase (DNA) I | 0.012 | ||
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 0.012 | ||
| FBXW7 | F-box and WD repeat domain containing 7 | 0.012 | ||
| MED1 | mediator complex subunit 1 | 0.012 | ||
| SMC5 | structural maintenance of chromosomes 5 | 0.012 | ||
| ANLN | anillin, actin binding protein | 0.012 | ||
| ZSWIM7 | zinc finger, SWIM-type containing 7 | 0.012 | ||
| POLR2K | polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa | 0.012 | ||
| NRD1 | nardilysin (N-arginine dibasic convertase) | 0.012 | ||
| CENPE | centromere protein E, 312kDa | 0.012 | ||
| FYN | FYN oncogene related to SRC, FGR, YES | 0.011 | ||
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.011 | ||
| FBXO4 | F-box protein 4 | 0.011 | ||
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.011 | ||
| PHF20 | PHD finger protein 20 | 0.011 | ||
| SNAI1 | snail homolog 1 (Drosophila) | 0.011 | ||
| MYO1C | myosin IC | 0.011 | ||
| MAPK1 | mitogen-activated protein kinase 1 | 0.011 | ||
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.011 | ||
| MED21 | mediator complex subunit 21 | 0.011 | ||
| AIRE | autoimmune regulator | 0.011 | ||
| INTS12 | integrator complex subunit 12 | 0.011 | ||
| LBR | lamin B receptor | 0.011 | ||
| ING1 | inhibitor of growth family, member 1 | 0.011 | ||
| EML4 | echinoderm microtubule associated protein like 4 | 0.011 | ||
| SOCS1 | suppressor of cytokine signaling 1 | 0.011 | ||
| SCAF11 | SR-related CTD-associated factor 11 | 0.011 | ||
| UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.011 | ||
| DEK | DEK oncogene | 0.011 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.011 | ||
| RIF1 | RAP1 interacting factor homolog (yeast) | 0.011 | ||
| CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.011 | ||
| USP34 | ubiquitin specific peptidase 34 | 0.010 | ||
| WBP4 | WW domain binding protein 4 (formin binding protein 21) | 0.010 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.010 | Fly | |
| ARRB1 | arrestin, beta 1 | 0.010 | ||
| EIF4E | eukaryotic translation initiation factor 4E | 0.010 | ||
| GSTM4 | glutathione S-transferase mu 4 | 0.010 | ||
| HIST1H2BB | histone cluster 1, H2bb | 0.010 | ||
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 | 0.010 | ||
| CCDC99 | coiled-coil domain containing 99 | 0.010 | ||
| POMP | proteasome maturation protein | 0.010 | ||
| HIST1H3F | histone cluster 1, H3f | 0.010 | ||
| HIST1H2AB | histone cluster 1, H2ab | 0.010 | ||
| SOCS2 | suppressor of cytokine signaling 2 | 0.010 | ||
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 | 0.010 | ||
| ZW10 | ZW10, kinetochore associated, homolog (Drosophila) | 0.010 | ||
| RANBP9 | RAN binding protein 9 | 0.010 | ||
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.010 |