Homo sapiens

24 known processes

SPOP

speckle-type POZ protein

(Aliases: TEF2)

SPOP biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of transcription involved in lymphatic endothelial cell fate commitment GO:0060849 2 0.977
ornithine metabolic process GO:0006591 3 0.744
lipid metabolic process GO:0006629 381 0.725
monocarboxylic acid metabolic process GO:0032787 185 0.708
intracellular receptor signaling pathway GO:0030522 104 0.708
vesicle targeting rough er to cis golgi GO:0048207 2 0.535
striated muscle cell proliferation GO:0014855 7 0.513
cellular lipid metabolic process GO:0044255 303 0.490
epithelial cell fate commitment GO:0072148 3 0.487
cellular macromolecule catabolic process GO:0044265 380 0.448
growth GO:0040007 202 0.423
multicellular organismal aging GO:0010259 3 0.410
alpha amino acid metabolic process GO:1901605 72 0.391
neuronal action potential GO:0019228 9 0.383
response to xenobiotic stimulus GO:0009410 30 0.349
negative regulation of protein metabolic process GO:0051248 391 0.333
Human
endothelial cell fate commitment GO:0060839 3 0.333
regulation of cell growth GO:0001558 135 0.332
negative regulation of phosphate metabolic process GO:0045936 267 0.326
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.326
Mouse
coagulation GO:0050817 78 0.322
vesicle mediated transport GO:0016192 371 0.321
regulation of cellular ketone metabolic process GO:0010565 50 0.316
fatty acid metabolic process GO:0006631 115 0.311
negative regulation of apoptotic process GO:0043066 316 0.307
rab protein signal transduction GO:0032482 4 0.307
regulation of lipid metabolic process GO:0019216 96 0.306
muscle cell proliferation GO:0033002 35 0.291
regulation of transcription from rna polymerase iii promoter GO:0006359 13 0.290
cellular amino acid metabolic process GO:0006520 116 0.264
post embryonic development GO:0009791 2 0.261
cellular ketone metabolic process GO:0042180 80 0.256
interspecies interaction between organisms GO:0044419 156 0.242
cell growth GO:0016049 160 0.240
transcription from rna polymerase iii promoter GO:0006383 19 0.238
modification by symbiont of host morphology or physiology GO:0044003 12 0.215
regulation of locomotion GO:0040012 329 0.214
negative regulation of transcription initiation from rna polymerase ii promoter GO:0060633 3 0.213
copii vesicle coating GO:0048208 2 0.213
limbic system development GO:0021761 3 0.213
modulation by virus of host morphology or physiology GO:0019048 10 0.204
ventricular cardiac muscle cell differentiation GO:0055012 1 0.204
regulation of endothelial cell migration GO:0010594 67 0.201
protein k33 linked ubiquitination GO:1990390 1 0.193
cardiocyte differentiation GO:0035051 23 0.186
modification dependent protein catabolic process GO:0019941 209 0.184
regulation of myelination GO:0031641 1 0.183
single organism membrane budding GO:1902591 10 0.181
regulation of growth GO:0040008 165 0.179
cardiac muscle tissue development GO:0048738 39 0.170
negative regulation of epithelial cell migration GO:0010633 38 0.169
negative regulation of phosphorus metabolic process GO:0010563 267 0.167
detection of bacterial lipoprotein GO:0042494 3 0.164
response to acid chemical GO:0001101 66 0.163
nucleoside triphosphate metabolic process GO:0009141 422 0.163
nucleoside triphosphate catabolic process GO:0009143 394 0.161
regulation of transferase activity GO:0051338 355 0.159
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.157
organophosphate catabolic process GO:0046434 430 0.156
purine ribonucleoside catabolic process GO:0046130 398 0.155
cellular response to xenobiotic stimulus GO:0071466 29 0.154
chemical homeostasis GO:0048878 306 0.153
Mouse
epithelium development GO:0060429 227 0.153
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.150
protein oligomerization GO:0051259 173 0.148
negative regulation of multicellular organismal process GO:0051241 317 0.146
endothelial cell migration GO:0043542 86 0.145
negative regulation of protein modification process GO:0031400 200 0.145
Human
nucleotide catabolic process GO:0009166 408 0.144
ribonucleoside triphosphate catabolic process GO:0009203 391 0.142
endosomal transport GO:0016197 129 0.141
striated muscle tissue development GO:0014706 59 0.139
regulation of protein kinase activity GO:0045859 289 0.133
regulation of epithelial cell proliferation GO:0050678 113 0.131
posttranscriptional regulation of gene expression GO:0010608 213 0.130
nervous system development GO:0007399 293 0.129
positive regulation of developmental process GO:0051094 314 0.129
lipid modification GO:0030258 84 0.128
guanosine containing compound metabolic process GO:1901068 244 0.128
vesicle targeting to from or within golgi GO:0048199 6 0.128
transmission of nerve impulse GO:0019226 11 0.127
lymphatic endothelial cell fate commitment GO:0060838 2 0.125
tumor necrosis factor superfamily cytokine production GO:0071706 45 0.122
cardiac muscle cell differentiation GO:0055007 15 0.121
viral process GO:0016032 146 0.121
cardiac muscle cell proliferation GO:0060038 6 0.120
purine ribonucleoside metabolic process GO:0046128 437 0.120
cellular response to acid chemical GO:0071229 44 0.118
purine nucleotide catabolic process GO:0006195 405 0.118
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.117
muscle tissue development GO:0060537 62 0.114
chromosome passenger complex localization to spindle midzone GO:0035853 1 0.114
epithelium migration GO:0090132 119 0.112
nucleoside catabolic process GO:0009164 408 0.111
regulation of tumor necrosis factor superfamily cytokine production GO:1903555 44 0.108
aging GO:0007568 66 0.106
negative regulation of locomotion GO:0040013 118 0.106
cytoplasmic transport GO:0016482 379 0.104
response to oxygen containing compound GO:1901700 369 0.104
regulation of kinase activity GO:0043549 314 0.103
purine nucleoside catabolic process GO:0006152 398 0.101
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.099
negative regulation of cellular component organization GO:0051129 235 0.098
system process GO:0003008 349 0.098
gtp catabolic process GO:0006184 237 0.097
ribonucleotide catabolic process GO:0009261 405 0.097
regulation of body fluid levels GO:0050878 99 0.097
chromatin organization GO:0006325 351 0.096
epithelial cell proliferation GO:0050673 128 0.095
protein tetramerization GO:0051262 47 0.093
hemostasis GO:0007599 76 0.092
neurological system process GO:0050877 163 0.091
protein localization to organelle GO:0033365 280 0.090
chemokine metabolic process GO:0050755 4 0.090
chemokine biosynthetic process GO:0042033 4 0.089
glycosyl compound catabolic process GO:1901658 413 0.088
interaction with host GO:0051701 42 0.088
membrane budding GO:0006900 28 0.087
cartilage development involved in endochondral bone morphogenesis GO:0060351 2 0.086
membrane organization GO:0061024 292 0.085
striated muscle cell differentiation GO:0051146 43 0.084
modification of morphology or physiology of other organism GO:0035821 43 0.084
glycerolipid metabolic process GO:0046486 107 0.083
regulation of receptor activity GO:0010469 47 0.083
actin filament organization GO:0007015 128 0.082
wound healing GO:0042060 115 0.082
ribonucleoside triphosphate metabolic process GO:0009199 412 0.077
growth of symbiont in host GO:0044117 1 0.077
embryonic camera type eye development GO:0031076 2 0.077
carbon catabolite regulation of transcription from rna polymerase ii promoter GO:0000429 3 0.076
ubiquitin dependent protein catabolic process GO:0006511 206 0.076
vasculature development GO:0001944 181 0.075
regulation of tumor necrosis factor production GO:0032680 43 0.075
proteasomal protein catabolic process GO:0010498 176 0.074
negative regulation of tumor necrosis factor production GO:0032720 20 0.074
negative regulation of kinase activity GO:0033673 106 0.074
cellular response to bacterial lipoprotein GO:0071220 3 0.074
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.073
renal sodium ion absorption GO:0070294 2 0.073
multi organism cellular process GO:0044764 156 0.073
action potential GO:0001508 34 0.073
distal tubule development GO:0072017 4 0.072
negative regulation of protein phosphorylation GO:0001933 140 0.072
epithelial cell differentiation GO:0030855 141 0.069
oogenesis GO:0048477 2 0.069
actin filament based process GO:0030029 224 0.068
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.068
response to biotic stimulus GO:0009607 276 0.068
cell morphogenesis GO:0000902 296 0.068
positive regulation of apoptotic process GO:0043065 246 0.067
Mouse
anterior posterior axis specification GO:0009948 2 0.066
endothelial cell differentiation GO:0045446 26 0.066
regulation of anatomical structure morphogenesis GO:0022603 286 0.066
negative regulation of cell migration GO:0030336 102 0.066
purine nucleoside triphosphate metabolic process GO:0009144 412 0.066
multicellular organismal signaling GO:0035637 34 0.064
endothelium development GO:0003158 33 0.064
negative regulation of growth GO:0045926 97 0.063
regulation of nucleoside metabolic process GO:0009118 209 0.062
negative regulation of axonogenesis GO:0050771 4 0.062
blastocyst formation GO:0001825 3 0.062
negative regulation of cyclin dependent protein serine threonine kinase activity GO:0045736 15 0.062
phosphatidylinositol metabolic process GO:0046488 53 0.060
regulation of ras protein signal transduction GO:0046578 155 0.059
embryo development GO:0009790 123 0.058
hippocampus development GO:0021766 1 0.058
positive regulation of cytokine production GO:0001819 167 0.058
intrinsic apoptotic signaling pathway GO:0097193 127 0.057
Mouse
heart growth GO:0060419 6 0.057
modification dependent macromolecule catabolic process GO:0043632 212 0.057
single organism membrane organization GO:0044802 268 0.057
protein catabolic process GO:0030163 325 0.057
protein homotetramerization GO:0051289 28 0.057
regulation of cell cycle GO:0051726 393 0.056
negative regulation of cell cycle GO:0045786 193 0.056
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.056
gtp metabolic process GO:0046039 239 0.055
cellular response to oxygen containing compound GO:1901701 276 0.055
regulation of rab gtpase activity GO:0032313 39 0.055
purine ribonucleotide catabolic process GO:0009154 404 0.054
segmentation GO:0035282 4 0.054
ribonucleoside monophosphate metabolic process GO:0009161 187 0.054
single organism cellular localization GO:1902580 332 0.053
ameboidal type cell migration GO:0001667 135 0.053
regulation of cytokine production GO:0001817 232 0.053
interleukin 17 production GO:0032620 12 0.053
immune response GO:0006955 307 0.053
purine containing compound catabolic process GO:0072523 411 0.052
wnt signaling pathway GO:0016055 156 0.052
nucleoside phosphate catabolic process GO:1901292 412 0.052
single organism reproductive process GO:0044702 98 0.051
ras protein signal transduction GO:0007265 73 0.051
purine nucleoside triphosphate catabolic process GO:0009146 392 0.051
endothelial cell proliferation GO:0001935 65 0.051
cellular response to triacyl bacterial lipopeptide GO:0071727 2 0.051
regulation of cell development GO:0060284 161 0.051
negative regulation of cell growth GO:0030308 83 0.051
glycerophospholipid metabolic process GO:0006650 84 0.051
regulation of transcription by galactose GO:0000409 1 0.050
regulation of cell motility GO:2000145 299 0.050
histone methylation GO:0016571 60 0.050
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.050
negative regulation of protein kinase activity GO:0006469 98 0.050
negative regulation of programmed cell death GO:0043069 321 0.049
regulation of gtpase activity GO:0043087 180 0.049
lymphocyte activation GO:0046649 133 0.049
regulation of nervous system development GO:0051960 88 0.049
detection of diacyl bacterial lipopeptide GO:0042496 2 0.048
xenobiotic metabolic process GO:0006805 28 0.048
positive regulation of interleukin 8 production GO:0032757 36 0.048
metal ion transport GO:0030001 272 0.048
rho protein signal transduction GO:0007266 26 0.047
humoral immune response GO:0006959 49 0.047
reproductive process GO:0022414 106 0.047
regulation of cell morphogenesis GO:0022604 153 0.046
renal sodium ion transport GO:0003096 2 0.046
response to diacyl bacterial lipopeptide GO:0071724 2 0.046
golgi vesicle transport GO:0048193 80 0.046
guanosine containing compound catabolic process GO:1901069 239 0.046
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.046
positive regulation of nucleotide metabolic process GO:0045981 230 0.046
positive regulation of transcription by galactose GO:0000411 1 0.045
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.045
Mouse
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.045
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.045
ribonucleoside catabolic process GO:0042454 406 0.045
response to triacyl bacterial lipopeptide GO:0071725 2 0.045
positive regulation of cellular catabolic process GO:0031331 284 0.044
cytokine production GO:0001816 247 0.044
cation transport GO:0006812 331 0.044
tissue migration GO:0090130 119 0.044
regulation of reactive oxygen species metabolic process GO:2000377 41 0.044
androgen receptor signaling pathway GO:0030521 34 0.044
cell development GO:0048468 328 0.044
negative regulation of cell proliferation GO:0008285 228 0.043
female pregnancy GO:0007565 17 0.043
receptor mediated endocytosis GO:0006898 84 0.043
translation GO:0006412 132 0.042
protein k48 linked ubiquitination GO:0070936 38 0.042
protein polyubiquitination GO:0000209 110 0.042
response to organonitrogen compound GO:0010243 156 0.042
vesicle targeting GO:0006903 7 0.042
chondroblast differentiation GO:0060591 2 0.041
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.041
endocytosis GO:0006897 159 0.041
cellular protein catabolic process GO:0044257 261 0.041
response to lipid GO:0033993 206 0.041
regulation of epithelial cell migration GO:0010632 93 0.040
regulation of protein localization GO:0032880 296 0.040
endomembrane system organization GO:0010256 196 0.040
small gtpase mediated signal transduction GO:0007264 78 0.040
cardiovascular system development GO:0072358 262 0.040
protein targeting GO:0006605 187 0.040
vesicle organization GO:0016050 62 0.040
protein ubiquitination GO:0016567 314 0.039
Human Mouse
positive regulation of gtp catabolic process GO:0033126 166 0.039
cell projection organization GO:0030030 252 0.039
cellular response to retinoic acid GO:0071300 19 0.039
regulation of small gtpase mediated signal transduction GO:0051056 156 0.039
regulation of cd4 positive alpha beta t cell differentiation GO:0043370 3 0.039
muscle structure development GO:0061061 98 0.039
cilium assembly GO:0042384 63 0.039
positive regulation of cell death GO:0010942 263 0.038
Mouse
positive regulation of cell proliferation GO:0008284 301 0.038
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 36 0.038
neurotransmitter secretion GO:0007269 4 0.038
lipid homeostasis GO:0055088 39 0.037
positive regulation of interleukin 5 production GO:0032754 3 0.037
protein homooligomerization GO:0051260 100 0.037
anterior posterior axis specification embryo GO:0008595 2 0.037
tripartite regional subdivision GO:0007351 2 0.036
positive regulation of nucleotide catabolic process GO:0030813 185 0.036
carbon catabolite activation of transcription GO:0045991 3 0.036
endochondral bone morphogenesis GO:0060350 3 0.035
endoplasmic reticulum organization GO:0007029 20 0.035
cellular response to lipid GO:0071396 127 0.035
blood coagulation GO:0007596 76 0.035
stem cell division GO:0017145 2 0.035
regulation of nucleotide catabolic process GO:0030811 205 0.035
negative regulation of proteolysis GO:0045861 132 0.035
regulation of cellular amino acid metabolic process GO:0006521 6 0.034
retrograde transport endosome to golgi GO:0042147 45 0.034
response to oxygen levels GO:0070482 100 0.034
regulation of protein serine threonine kinase activity GO:0071900 179 0.034
morphogenesis of embryonic epithelium GO:0016331 4 0.034
regulation of immune response GO:0050776 201 0.034
regulation of gtp catabolic process GO:0033124 180 0.034
chordate embryonic development GO:0043009 34 0.034
epithelial cell migration GO:0010631 119 0.034
activation of innate immune response GO:0002218 55 0.034
response to hormone GO:0009725 175 0.034
developmental process involved in reproduction GO:0003006 66 0.033
cellular amine metabolic process GO:0044106 41 0.033
sodium ion transport GO:0006814 61 0.033
ion homeostasis GO:0050801 230 0.033
endoplasmic reticulum tubular network organization GO:0071786 8 0.033
peptidyl lysine modification GO:0018205 144 0.032
positive regulation of hydrolase activity GO:0051345 331 0.032
response to abiotic stimulus GO:0009628 336 0.032
female genitalia development GO:0030540 2 0.032
epithelial tube morphogenesis GO:0060562 38 0.032
embryonic placenta development GO:0001892 1 0.032
regulation of cell cycle process GO:0010564 266 0.031
signal transduction by phosphorylation GO:0023014 297 0.031
regulation of nucleotide metabolic process GO:0006140 269 0.031
placenta development GO:0001890 10 0.031
morphogenesis of a branching structure GO:0001763 21 0.031
regulation of chemokine biosynthetic process GO:0045073 4 0.031
regulation of endothelial cell proliferation GO:0001936 56 0.031
regulation of muscle cell differentiation GO:0051147 31 0.030
purine nucleoside monophosphate metabolic process GO:0009126 186 0.030
negative regulation of cellular protein metabolic process GO:0032269 353 0.030
Human
negative regulation of catabolic process GO:0009895 104 0.030
regulation of cytokinesis GO:0032465 45 0.030
negative regulation of cell death GO:0060548 345 0.030
angiogenesis involved in wound healing GO:0060055 4 0.030
positive regulation of defense response GO:0031349 87 0.030
mammary gland morphogenesis GO:0060443 2 0.029
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.029
protein processing GO:0016485 226 0.029
interleukin 6 production GO:0032635 37 0.029
kidney morphogenesis GO:0060993 19 0.029
protein dna complex subunit organization GO:0071824 80 0.029
tube morphogenesis GO:0035239 95 0.029
carbon catabolite activation of transcription from rna polymerase ii promoter GO:0000436 3 0.029
retinoic acid receptor signaling pathway GO:0048384 13 0.028
regulation of proteolysis GO:0030162 293 0.028
generation of neurons GO:0048699 152 0.028
positive regulation of nf kappab transcription factor activity GO:0051092 81 0.028
positive regulation of lymphocyte activation GO:0051251 73 0.028
positive regulation of immune system process GO:0002684 283 0.028
vesicle localization GO:0051648 26 0.028
outflow tract septum morphogenesis GO:0003148 4 0.028
embryonic epithelial tube formation GO:0001838 4 0.028
histone modification GO:0016570 251 0.027
negative regulation of axon extension GO:0030517 2 0.027
regulation of purine nucleotide metabolic process GO:1900542 264 0.027
response to peptidoglycan GO:0032494 3 0.027
lipid localization GO:0010876 106 0.026
blastoderm segmentation GO:0007350 2 0.026
positive regulation of ras gtpase activity GO:0032320 117 0.026
growth involved in symbiotic interaction GO:0044110 2 0.026
er to golgi vesicle mediated transport GO:0006888 19 0.026
nucleoside monophosphate metabolic process GO:0009123 191 0.026
positive regulation of programmed cell death GO:0043068 249 0.026
Mouse
amine metabolic process GO:0009308 44 0.026
regulation of growth of symbiont in host GO:0044126 1 0.026
cardiac muscle tissue growth GO:0055017 6 0.025
regulation of transcription involved in cell fate commitment GO:0060850 6 0.025
positive regulation of interleukin 23 production GO:0032747 4 0.025
secretion GO:0046903 254 0.025
positive regulation of leukocyte activation GO:0002696 80 0.025
actin cytoskeleton organization GO:0030036 207 0.025
cellular component morphogenesis GO:0032989 314 0.024
regulation of protein transport GO:0051223 213 0.024
apoptotic signaling pathway GO:0097190 268 0.024
Mouse
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.024
response to retinoic acid GO:0032526 33 0.024
regulation of striated muscle tissue development GO:0016202 26 0.024
regulation of synaptic plasticity GO:0048167 3 0.024
regulation of interleukin 17 production GO:0032660 12 0.024
cell division GO:0051301 168 0.024
negative regulation of epithelial cell proliferation GO:0050680 48 0.024
toll like receptor 4 signaling pathway GO:0034142 12 0.024
negative regulation of transferase activity GO:0051348 124 0.024
multicellular organismal response to stress GO:0033555 1 0.024
positive regulation of mapk cascade GO:0043410 190 0.024
response to bacterial lipopeptide GO:0070339 3 0.024
regulation of cell differentiation GO:0045595 393 0.024
sister chromatid segregation GO:0000819 54 0.024
cell cycle phase transition GO:0044770 173 0.024
carbohydrate metabolic process GO:0005975 207 0.024
negative regulation of growth of symbiont involved in interaction with host GO:0044146 2 0.023
innate immune response GO:0045087 178 0.023
regulation of purine nucleotide catabolic process GO:0033121 205 0.023
locomotory behavior GO:0007626 1 0.023
female gamete generation GO:0007292 2 0.023
covalent chromatin modification GO:0016569 254 0.023
lymphatic endothelial cell differentiation GO:0060836 3 0.023
dna packaging GO:0006323 77 0.023
protein deubiquitination GO:0016579 79 0.023
modulation of growth of symbiont involved in interaction with host GO:0044144 2 0.023
hematopoietic or lymphoid organ development GO:0048534 186 0.023
dna templated transcription initiation GO:0006352 35 0.023
positive regulation of gtpase activity GO:0043547 166 0.022
nucleocytoplasmic transport GO:0006913 176 0.022
cerebellum development GO:0021549 2 0.022
negative regulation of rho protein signal transduction GO:0035024 7 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.022
distal tubule morphogenesis GO:0072156 3 0.022
renal system development GO:0072001 63 0.022
tumor necrosis factor production GO:0032640 43 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.022
central nervous system development GO:0007417 123 0.022
response to endoplasmic reticulum stress GO:0034976 49 0.022
Mouse
negative regulation of cilium assembly GO:1902018 3 0.021
positive regulation of cytoplasmic transport GO:1903651 82 0.021
negative regulation of cellular component movement GO:0051271 106 0.021
positive regulation of protein import into nucleus GO:0042307 46 0.021
regulation of gluconeogenesis by regulation of transcription from rna polymerase ii promoter GO:0035947 1 0.021
interleukin 8 production GO:0032637 51 0.021
interferon alpha biosynthetic process GO:0045349 4 0.021
hypothalamus development GO:0021854 1 0.021
digestion GO:0007586 22 0.021
establishment of protein localization to organelle GO:0072594 172 0.021
nitrogen compound transport GO:0071705 191 0.021
adult locomotory behavior GO:0008344 1 0.021
lymphocyte proliferation GO:0046651 70 0.021
neural tube closure GO:0001843 3 0.021
regulation of leukocyte activation GO:0002694 115 0.020
regulation of cell projection organization GO:0031344 107 0.020
defense response to fungus GO:0050832 4 0.020
protein import GO:0017038 130 0.020
response to external biotic stimulus GO:0043207 261 0.020
defense response GO:0006952 315 0.020
regulation of protein processing GO:0070613 150 0.020
metal ion homeostasis GO:0055065 169 0.020
intracellular protein transport GO:0006886 270 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
reproduction GO:0000003 63 0.020
regulation of meiotic cell cycle GO:0051445 4 0.020
protein maturation GO:0051604 233 0.020
regulation of rab protein signal transduction GO:0032483 39 0.020
positive regulation of cellular component organization GO:0051130 376 0.020
determination of adult lifespan GO:0008340 2 0.020
spermatid differentiation GO:0048515 4 0.020
negative regulation of protein processing GO:0010955 142 0.020
positive regulation of type i interferon production GO:0032481 20 0.020
positive regulation of cell cycle process GO:0090068 106 0.020
cellular response to oxidative stress GO:0034599 85 0.020
rna splicing GO:0008380 131 0.019
atp metabolic process GO:0046034 176 0.019
cellular cation homeostasis GO:0030003 163 0.019
gland development GO:0048732 48 0.019
neural tube formation GO:0001841 3 0.019
negative regulation of neuron projection development GO:0010977 15 0.019
regulation of interferon gamma production GO:0032649 36 0.019
regulation of intracellular steroid hormone receptor signaling pathway GO:0033143 32 0.019
protein modification by small protein removal GO:0070646 92 0.019
cilium organization GO:0044782 68 0.019
maintenance of location GO:0051235 112 0.019
positive regulation of immune effector process GO:0002699 40 0.019
monovalent inorganic cation transport GO:0015672 128 0.019
cartilage condensation GO:0001502 1 0.019
negative regulation of protein catabolic process GO:0042177 59 0.019
primary neural tube formation GO:0014020 3 0.019
cd4 positive alpha beta t cell differentiation GO:0043367 4 0.019
cell projection morphogenesis GO:0048858 129 0.019
heart development GO:0007507 95 0.019
positive regulation of cell division GO:0051781 59 0.019
pharynx development GO:0060465 1 0.019
positive regulation of interleukin 13 production GO:0032736 4 0.019
positive regulation of nucleoside metabolic process GO:0045979 186 0.019
positive regulation of organic acid transport GO:0032892 3 0.018
positive regulation of catabolic process GO:0009896 310 0.018
organ growth GO:0035265 12 0.018
cellular response to bacterial lipopeptide GO:0071221 3 0.018
response to inorganic substance GO:0010035 127 0.018
nucleoside monophosphate catabolic process GO:0009125 159 0.018
regulation of interferon beta production GO:0032648 22 0.018
t helper cell differentiation GO:0042093 4 0.018
regulation of intracellular transport GO:0032386 195 0.018
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.018
negative regulation of cell projection organization GO:0031345 22 0.018
regulation of cytoplasmic transport GO:1903649 149 0.018
negative regulation of intracellular protein transport GO:0090317 42 0.018
multi multicellular organism process GO:0044706 18 0.018
renal system process GO:0003014 25 0.018
regulation of protein maturation GO:1903317 150 0.018
response to bacterial lipoprotein GO:0032493 3 0.018
metencephalon development GO:0022037 2 0.017
type i interferon production GO:0032606 27 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
regulation of cellular response to stress GO:0080135 244 0.017
Mouse
lymph vessel development GO:0001945 9 0.017
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.017
negative regulation of endothelial cell proliferation GO:0001937 20 0.017
regulation of defense response GO:0031347 154 0.017
negative regulation of growth of symbiont in host GO:0044130 1 0.017
negative regulation of cell cycle process GO:0010948 121 0.017
embryonic morphogenesis GO:0048598 85 0.017
regulation of fatty acid metabolic process GO:0019217 24 0.017
histone h4 acetylation GO:0043967 47 0.017
negative regulation of organelle organization GO:0010639 126 0.017
ribonucleoside monophosphate catabolic process GO:0009158 158 0.017
startle response GO:0001964 3 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017

SPOP disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.066
disease of cellular proliferation DOID:14566 174 0.066
organ system cancer DOID:0050686 164 0.065
disease by infectious agent DOID:0050117 34 0.020
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
disease of mental health DOID:150 70 0.019