IMP
Process View
negative regulation of cyclin dependent protein serine threonine kinase activity
Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cyclin dependent protein serine threonine kinase activity"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| SRF | serum response factor (c-fos serum response element-binding transcription factor) | 0.669 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.456 | Mouse | |
| CCND3 | cyclin D3 | 0.096 | ||
| BTRC | beta-transducin repeat containing | 0.090 | ||
| RARA | retinoic acid receptor, alpha | 0.078 | ||
| CDK6 | cyclin-dependent kinase 6 | 0.067 | ||
| RB1 | retinoblastoma 1 | 0.063 | ||
| MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.062 | ||
| SPOP | speckle-type POZ protein | 0.062 | ||
| CCND1 | cyclin D1 | 0.058 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.058 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.058 | Mouse | |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.057 | ||
| MED25 | mediator complex subunit 25 | 0.048 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.042 | ||
| SKP1 | S-phase kinase-associated protein 1 | 0.041 | ||
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.039 | ||
| NCOA1 | nuclear receptor coactivator 1 | 0.037 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.030 | ||
| MOBKL1B | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.026 | ||
| SNAI1 | snail homolog 1 (Drosophila) | 0.026 | ||
| JUB | jub, ajuba homolog (Xenopus laevis) | 0.021 | ||
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.020 | ||
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.020 | ||
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.019 | ||
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.019 | ||
| YAP1 | Yes-associated protein 1 | 0.019 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.016 | ||
| MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.015 | ||
| SFN | stratifin | 0.015 | ||
| LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.015 | ||
| PINK1 | PTEN induced putative kinase 1 | 0.014 | ||
| PROX1 | prospero homeobox 1 | 0.014 | ||
| FAM46A | family with sequence similarity 46, member A | 0.013 | ||
| TNIP1 | TNFAIP3 interacting protein 1 | 0.013 | ||
| BRCA2 | breast cancer 2, early onset | 0.012 | ||
| SMAD1 | SMAD family member 1 | 0.011 | ||
| MLL | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | 0.011 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.011 | ||
| STK38L | serine/threonine kinase 38 like | 0.011 | ||
| PRNP | prion protein | 0.011 |