Homo sapiens

75 known processes

DTL

denticleless homolog (Drosophila)

(Aliases: DCAF2,L2DTL,RAMP,CDT2)

DTL biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna repair GO:0006281 198 0.995
cellular response to dna damage stimulus GO:0006974 379 0.981
double strand break repair GO:0006302 101 0.798
chromatin modification GO:0016568 298 0.787
double strand break repair via homologous recombination GO:0000724 50 0.709
nucleoside triphosphate metabolic process GO:0009141 422 0.680
dna replication GO:0006260 116 0.620
chromatin organization GO:0006325 351 0.595
response to radiation GO:0009314 151 0.591
recombinational repair GO:0000725 50 0.583
mitotic cell cycle GO:0000278 326 0.549
Zebrafish
mitotic cell cycle phase transition GO:0044772 162 0.515
Zebrafish
nucleoside triphosphate catabolic process GO:0009143 394 0.496
purine ribonucleoside metabolic process GO:0046128 437 0.481
cell cycle phase transition GO:0044770 173 0.426
Zebrafish
regulation of cell cycle phase transition GO:1901987 126 0.418
Zebrafish
nucleoside catabolic process GO:0009164 408 0.370
ribonucleotide catabolic process GO:0009261 405 0.354
dna biosynthetic process GO:0071897 40 0.353
nucleoside phosphate catabolic process GO:1901292 412 0.341
dna recombination GO:0006310 77 0.335
chromosome segregation GO:0007059 114 0.327
purine nucleoside monophosphate catabolic process GO:0009128 158 0.325
dna damage checkpoint GO:0000077 68 0.324
purine nucleoside catabolic process GO:0006152 398 0.318
regulation of dna metabolic process GO:0051052 153 0.305
atp catabolic process GO:0006200 157 0.289
mitotic cell cycle process GO:1903047 286 0.278
Zebrafish
regulation of cell cycle GO:0051726 393 0.273
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.268
ribonucleoside triphosphate metabolic process GO:0009199 412 0.268
ribonucleoside catabolic process GO:0042454 406 0.260
response to abiotic stimulus GO:0009628 336 0.252
regulation of mitotic cell cycle GO:0007346 189 0.251
Zebrafish
nucleoside monophosphate catabolic process GO:0009125 159 0.246
nuclear division GO:0000280 128 0.244
covalent chromatin modification GO:0016569 254 0.235
negative regulation of cell death GO:0060548 345 0.233
response to uv GO:0009411 73 0.214
response to light stimulus GO:0009416 87 0.213
purine ribonucleoside catabolic process GO:0046130 398 0.212
purine nucleotide catabolic process GO:0006195 405 0.205
regulation of cell cycle process GO:0010564 266 0.203
Zebrafish
nucleoside monophosphate metabolic process GO:0009123 191 0.201
ribonucleoside triphosphate catabolic process GO:0009203 391 0.200
ribonucleoside monophosphate metabolic process GO:0009161 187 0.198
sex determination GO:0007530 3 0.193
dna dependent dna replication GO:0006261 44 0.191
organophosphate catabolic process GO:0046434 430 0.185
purine containing compound catabolic process GO:0072523 411 0.184
negative regulation of apoptotic process GO:0043066 316 0.184
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.182
purine nucleoside triphosphate catabolic process GO:0009146 392 0.179
positive regulation of cell proliferation GO:0008284 301 0.177
mitotic cell cycle checkpoint GO:0007093 68 0.177
Zebrafish
embryo development GO:0009790 123 0.169
Worm
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.161
dna conformation change GO:0071103 113 0.160
internal protein amino acid acetylation GO:0006475 101 0.156
purine nucleoside monophosphate metabolic process GO:0009126 186 0.155
cell division GO:0051301 168 0.155
dna integrity checkpoint GO:0031570 71 0.153
negative regulation of cell cycle process GO:0010948 121 0.151
Zebrafish
histone threonine phosphorylation GO:0035405 7 0.145
atp metabolic process GO:0046034 176 0.138
regulation of response to dna damage stimulus GO:2001020 94 0.136
reproductive process GO:0022414 106 0.134
Worm
vesicle mediated transport GO:0016192 371 0.131
Worm
purine ribonucleotide catabolic process GO:0009154 404 0.127
cell development GO:0048468 328 0.126
cellular ketone metabolic process GO:0042180 80 0.125
g1 s transition of mitotic cell cycle GO:0000082 78 0.119
nucleotide catabolic process GO:0009166 408 0.113
microtubule based process GO:0007017 210 0.113
translesion synthesis GO:0019985 8 0.112
purine nucleoside triphosphate metabolic process GO:0009144 412 0.111
ribonucleoside monophosphate catabolic process GO:0009158 158 0.107
anatomical structure homeostasis GO:0060249 100 0.104
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.103
negative regulation of cell cycle phase transition GO:1901988 89 0.103
Zebrafish
sex differentiation GO:0007548 45 0.099
Worm
embryo development ending in birth or egg hatching GO:0009792 34 0.097
Worm
glycosyl compound catabolic process GO:1901658 413 0.095
cell activation GO:0001775 213 0.093
cellular response to radiation GO:0071478 65 0.093
single organism reproductive process GO:0044702 98 0.091
Worm
sister chromatid segregation GO:0000819 54 0.089
regulation of g1 s transition of mitotic cell cycle GO:2000045 40 0.088
circulatory system development GO:0072359 262 0.087
negative regulation of mitotic cell cycle GO:0045930 102 0.087
Zebrafish
post embryonic development GO:0009791 2 0.085
Worm
regulation of cellular response to stress GO:0080135 244 0.083
cardiovascular system development GO:0072358 262 0.081
response to ionizing radiation GO:0010212 65 0.078
cell cell signaling GO:0007267 155 0.075
positive regulation of catabolic process GO:0009896 310 0.071
regulation of protein catabolic process GO:0042176 155 0.071
microtubule cytoskeleton organization GO:0000226 176 0.069
cell cycle g1 s phase transition GO:0044843 80 0.068
macromolecule methylation GO:0043414 97 0.068
regulation of dna recombination GO:0000018 23 0.067
cellular response to ionizing radiation GO:0071479 32 0.066
cellular component morphogenesis GO:0032989 314 0.066
negative regulation of cell cycle GO:0045786 193 0.064
Zebrafish
protein modification by small protein conjugation GO:0032446 342 0.064
cell fate commitment GO:0045165 27 0.061
histone modification GO:0016570 251 0.061
developmental process involved in reproduction GO:0003006 66 0.060
Worm
cellular macromolecular complex assembly GO:0034622 324 0.058
negative regulation of programmed cell death GO:0043069 321 0.057
mitotic nuclear division GO:0007067 119 0.056
cellular response to abiotic stimulus GO:0071214 117 0.055
regulation of chromosome organization GO:0033044 103 0.053
cellular macromolecule catabolic process GO:0044265 380 0.052
nervous system development GO:0007399 293 0.051
Fly
blastocyst development GO:0001824 3 0.051
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.051
immune effector process GO:0002252 159 0.050
mitotic dna integrity checkpoint GO:0044774 30 0.049
Zebrafish
positive regulation of cell cycle process GO:0090068 106 0.048
histone acetylation GO:0016573 93 0.048
amine metabolic process GO:0009308 44 0.047
lymphocyte mediated immunity GO:0002449 48 0.046
mitotic sister chromatid segregation GO:0000070 53 0.045
regulation of chromosome segregation GO:0051983 44 0.045
lymphocyte activation GO:0046649 133 0.045
positive regulation of hydrolase activity GO:0051345 331 0.044
meiosis i GO:0007127 4 0.042
cellular amino acid metabolic process GO:0006520 116 0.042
wnt signaling pathway GO:0016055 156 0.042
regulation of dna repair GO:0006282 47 0.042
response to organic cyclic compound GO:0014070 204 0.042
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.041
Zebrafish
leukocyte activation GO:0045321 164 0.040
immune system development GO:0002520 195 0.040
positive regulation of organelle organization GO:0010638 195 0.040
reproduction GO:0000003 63 0.038
Worm
organelle assembly GO:0070925 176 0.038
organelle fission GO:0048285 149 0.037
mismatch repair GO:0006298 15 0.037
nucleotide biosynthetic process GO:0009165 109 0.037
cell cycle checkpoint GO:0000075 117 0.037
endocytosis GO:0006897 159 0.037
Worm
protein alkylation GO:0008213 74 0.034
organ morphogenesis GO:0009887 147 0.034
immune response GO:0006955 307 0.033
microtubule organizing center organization GO:0031023 62 0.033
multicellular organismal aging GO:0010259 3 0.032
modification dependent macromolecule catabolic process GO:0043632 212 0.032
organophosphate biosynthetic process GO:0090407 163 0.031
regulation of mitotic cell cycle phase transition GO:1901990 118 0.031
Zebrafish
somatic hypermutation of immunoglobulin genes GO:0016446 1 0.031
regulation of double strand break repair via homologous recombination GO:0010569 11 0.031
regulation of dna replication GO:0006275 68 0.031
modification dependent protein catabolic process GO:0019941 209 0.031
peptidyl lysine modification GO:0018205 144 0.028
response to inorganic substance GO:0010035 127 0.028
centrosome separation GO:0051299 3 0.027
regulation of cellular amino acid metabolic process GO:0006521 6 0.027
cellular response to endogenous stimulus GO:0071495 336 0.027
hemopoiesis GO:0030097 180 0.027
gonad development GO:0008406 34 0.027
Worm
cell morphogenesis GO:0000902 296 0.027
reproductive system development GO:0061458 56 0.026
Worm
ubiquitin dependent protein catabolic process GO:0006511 206 0.026
negative regulation of dna metabolic process GO:0051053 57 0.026
protein catabolic process GO:0030163 325 0.026
meiotic nuclear division GO:0007126 10 0.026
regulation of chromatin organization GO:1902275 56 0.026
histone methylation GO:0016571 60 0.025
cell projection organization GO:0030030 252 0.025
regulation of cell division GO:0051302 116 0.025
somatic diversification of immunoglobulins involved in immune response GO:0002208 3 0.024
regulation of cellular ketone metabolic process GO:0010565 50 0.024
reciprocal meiotic recombination GO:0007131 4 0.024
dna duplex unwinding GO:0032508 30 0.023
regulation of cell cycle g1 s phase transition GO:1902806 42 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.023
cellular response to organonitrogen compound GO:0071417 124 0.023
regulation of proteolysis GO:0030162 293 0.022
actin filament based process GO:0030029 224 0.022
dna geometric change GO:0032392 32 0.022
oogenesis GO:0048477 2 0.022
base excision repair GO:0006284 21 0.022
heart development GO:0007507 95 0.022
regulation of protein localization GO:0032880 296 0.021
maintenance of location GO:0051235 112 0.021
female gamete generation GO:0007292 2 0.021
regulation of chromatin modification GO:1903308 51 0.021
gene conversion GO:0035822 1 0.021
telomere maintenance GO:0000723 32 0.021
regulation of gene expression epigenetic GO:0040029 73 0.021
protein processing GO:0016485 226 0.021
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.020
regulation of proteasomal protein catabolic process GO:0061136 87 0.020
maintenance of location in cell GO:0051651 62 0.020
chromatin remodeling GO:0006338 55 0.020
regulation of kinase activity GO:0043549 314 0.020
response to nitrogen compound GO:1901698 184 0.020
positive regulation of programmed cell death GO:0043068 249 0.020
carbohydrate derivative biosynthetic process GO:1901137 207 0.019
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.019
apoptotic signaling pathway GO:0097190 268 0.019
methylation GO:0032259 106 0.019
meiotic chromosome segregation GO:0045132 4 0.019
g2 dna damage checkpoint GO:0031572 26 0.019
neurogenesis GO:0022008 169 0.019
Fly
isotype switching GO:0045190 3 0.019
positive regulation of transport GO:0051050 336 0.019
proteasomal protein catabolic process GO:0010498 176 0.019
single organism cellular localization GO:1902580 332 0.018
cellular amine metabolic process GO:0044106 41 0.018
anatomical structure formation involved in morphogenesis GO:0048646 284 0.018
negative regulation of protein catabolic process GO:0042177 59 0.018
hematopoietic or lymphoid organ development GO:0048534 186 0.018
positive regulation of cellular catabolic process GO:0031331 284 0.017
positive regulation of dna metabolic process GO:0051054 73 0.017
multicellular organism reproduction GO:0032504 42 0.017
dna packaging GO:0006323 77 0.017
oxidation reduction process GO:0055114 396 0.017
receptor mediated endocytosis GO:0006898 84 0.017
Worm
telomere organization GO:0032200 33 0.017
regulation of transferase activity GO:0051338 355 0.017
regulation of protein maturation GO:1903317 150 0.016
regulation of wnt signaling pathway GO:0030111 123 0.016
cell fate determination GO:0001709 3 0.016
negative regulation of dna recombination GO:0045910 6 0.016
negative regulation of catalytic activity GO:0043086 335 0.016
leukocyte mediated immunity GO:0002443 59 0.015
positive regulation of cell cycle GO:0045787 140 0.015
secretion GO:0046903 254 0.015
regulation of mapk cascade GO:0043408 262 0.015
peptidyl lysine acetylation GO:0018394 101 0.015
positive regulation of mitotic cell cycle GO:0045931 60 0.015
protein oligomerization GO:0051259 173 0.015
regulation of cellular amine metabolic process GO:0033238 11 0.015
dna catabolic process GO:0006308 49 0.015
b cell activation GO:0042113 33 0.015
meiotic cell cycle process GO:1903046 8 0.015
somatic diversification of immune receptors via somatic mutation GO:0002566 1 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 71 0.014
response to other organism GO:0051707 261 0.014
cell cycle g2 m phase transition GO:0044839 43 0.014
regulation of mitotic sister chromatid segregation GO:0033047 27 0.014
cell part morphogenesis GO:0032990 137 0.014
reproductive structure development GO:0048608 55 0.014
Worm
response to external biotic stimulus GO:0043207 261 0.013
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
humoral immune response GO:0006959 49 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
internal peptidyl lysine acetylation GO:0018393 97 0.013
signal transduction in response to dna damage GO:0042770 57 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
positive regulation of cell division GO:0051781 59 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
response to drug GO:0042493 81 0.012
determination of adult lifespan GO:0008340 2 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
protein acylation GO:0043543 138 0.012
dna unwinding involved in dna replication GO:0006268 2 0.012
cell activation involved in immune response GO:0002263 30 0.012
response to purine containing compound GO:0014074 40 0.011
guanosine containing compound metabolic process GO:1901068 244 0.011
lagging strand elongation GO:0006273 3 0.011
cellular protein complex assembly GO:0043623 188 0.011
cell cycle arrest GO:0007050 71 0.011
dna modification GO:0006304 27 0.011
sister chromatid cohesion GO:0007062 24 0.011
negative regulation of cellular protein metabolic process GO:0032269 353 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
lymphocyte activation involved in immune response GO:0002285 20 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
regulation of protein processing GO:0070613 150 0.011
regeneration GO:0031099 4 0.011
embryonic organ development GO:0048568 36 0.011
chromosome separation GO:0051304 23 0.011
chromatin silencing GO:0006342 12 0.010
biological adhesion GO:0022610 331 0.010
protein homooligomerization GO:0051260 100 0.010
peptidyl serine phosphorylation GO:0018105 101 0.010
dna strand elongation involved in dna replication GO:0006271 3 0.010
negative regulation of gene expression epigenetic GO:0045814 19 0.010
somatic recombination of immunoglobulin genes involved in immune response GO:0002204 3 0.010
multi organism reproductive process GO:0044703 54 0.010
cellular response to purine containing compound GO:0071415 3 0.010
regulation of mitosis GO:0007088 63 0.010
chromosome condensation GO:0030261 15 0.010
microtubule anchoring GO:0034453 24 0.010
lymphocyte proliferation GO:0046651 70 0.010
regulation of nucleotide catabolic process GO:0030811 205 0.010
chromatin assembly or disassembly GO:0006333 78 0.010

DTL disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.038
cancer DOID:162 167 0.010