Homo sapiens

240 known processes

FLNA

filamin A, alpha

(Aliases: ABP-280,MNS,ABPX,FLN1,FLN,OPD1,XLVD,OPD2,OPD,XMVD,DKFZp434P031,FLN-A,NHBP,FMD,CVD1)

FLNA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
actin cytoskeleton organization GO:0030036 207 1.000
actin filament based process GO:0030029 224 1.000
actin filament organization GO:0007015 128 1.000
cell development GO:0048468 328 1.000
Mouse Fly
cell substrate adhesion GO:0031589 132 1.000
regulation of actin cytoskeleton organization GO:0032956 116 1.000
cellular component morphogenesis GO:0032989 314 1.000
single organismal cell cell adhesion GO:0016337 148 1.000
post embryonic development GO:0009791 2 1.000
Fly
anatomical structure formation involved in morphogenesis GO:0048646 284 1.000
tube morphogenesis GO:0035239 95 1.000
regulation of locomotion GO:0040012 329 1.000
cell matrix adhesion GO:0007160 85 0.999
protein localization to membrane GO:0072657 160 0.999
chemotaxis GO:0006935 157 0.999
Fly
biological adhesion GO:0022610 331 0.999
cellular extravasation GO:0045123 21 0.999
organ morphogenesis GO:0009887 147 0.999
Worm
cellular component assembly involved in morphogenesis GO:0010927 73 0.998
cell morphogenesis GO:0000902 296 0.998
regulation of body fluid levels GO:0050878 99 0.998
regulation of cytoskeleton organization GO:0051493 177 0.998
Fly
cell adhesion GO:0007155 325 0.998
cell activation GO:0001775 213 0.998
integrin mediated signaling pathway GO:0007229 32 0.998
single organism cell adhesion GO:0098602 179 0.997
actomyosin structure organization GO:0031032 59 0.997
cellular amine metabolic process GO:0044106 41 0.997
cardiac muscle tissue development GO:0048738 39 0.997
transforming growth factor beta receptor signaling pathway GO:0007179 76 0.997
epithelial cell differentiation GO:0030855 141 0.997
Fly
positive regulation of cellular component organization GO:0051130 376 0.996
Fly
muscle organ development GO:0007517 56 0.996
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.996
muscle cell development GO:0055001 29 0.995
tube development GO:0035295 125 0.995
muscle structure development GO:0061061 98 0.995
leukocyte cell cell adhesion GO:0007159 37 0.995
cell matrix adhesion involved in ameboidal cell migration GO:0003366 2 0.994
i kappab kinase nf kappab signaling GO:0007249 166 0.993
circulatory system development GO:0072359 262 0.993
cell morphogenesis involved in differentiation GO:0000904 144 0.992
Mouse Fly
regulation of cell motility GO:2000145 299 0.991
regulation of actin filament polymerization GO:0030833 50 0.991
regulation of protein localization GO:0032880 296 0.991
adenylate cyclase inhibiting g protein coupled receptor signaling pathway GO:0007193 22 0.990
blood vessel endothelial cell migration GO:0043534 42 0.990
inorganic ion transmembrane transport GO:0098660 231 0.990
regulation of cell migration GO:0030334 289 0.989
regulation of cellular ketone metabolic process GO:0010565 50 0.989
cell junction assembly GO:0034329 67 0.989
ameboidal type cell migration GO:0001667 135 0.989
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.989
cellular response to growth factor stimulus GO:0071363 197 0.987
negative regulation of locomotion GO:0040013 118 0.987
sensory perception GO:0007600 103 0.986
response to growth factor GO:0070848 205 0.985
female gamete generation GO:0007292 2 0.984
Worm Fly
taxis GO:0042330 157 0.983
Fly
system process GO:0003008 349 0.983
Fly
axonogenesis GO:0007409 31 0.983
Fly
positive regulation of axon extension GO:0045773 4 0.983
hemostasis GO:0007599 76 0.983
cell chemotaxis GO:0060326 112 0.983
coagulation GO:0050817 78 0.983
generation of neurons GO:0048699 152 0.982
Fly
regulation of cell differentiation GO:0045595 393 0.982
Fly
tissue morphogenesis GO:0048729 96 0.982
Fly
neurogenesis GO:0022008 169 0.981
Fly
inorganic cation transmembrane transport GO:0098662 194 0.981
single organism cellular localization GO:1902580 332 0.980
homotypic cell cell adhesion GO:0034109 47 0.980
nervous system development GO:0007399 293 0.980
Fly
regulation of cellular component movement GO:0051270 334 0.978
cell projection organization GO:0030030 252 0.978
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.977
organelle assembly GO:0070925 176 0.976
epithelial cell migration GO:0010631 119 0.975
positive regulation of transport GO:0051050 336 0.973
metal ion transport GO:0030001 272 0.973
actin filament bundle organization GO:0061572 54 0.971
stress fiber assembly GO:0043149 40 0.968
muscle system process GO:0003012 81 0.965
purine ribonucleoside catabolic process GO:0046130 398 0.964
neuron projection development GO:0031175 106 0.964
Fly
peptidyl tyrosine phosphorylation GO:0018108 170 0.963
negative regulation of cellular component movement GO:0051271 106 0.963
positive regulation of cell adhesion GO:0045785 84 0.962
motor neuron axon guidance GO:0008045 2 0.961
Fly
negative regulation of cell migration GO:0030336 102 0.961
striated muscle cell differentiation GO:0051146 43 0.961
transmembrane transport GO:0055085 399 0.959
mapk cascade GO:0000165 288 0.959
protein localization to plasma membrane GO:0072659 93 0.958
positive regulation of map kinase activity GO:0043406 80 0.957
regulation of actin filament based process GO:0032970 141 0.955
cation transmembrane transport GO:0098655 238 0.953
cellular amino acid metabolic process GO:0006520 116 0.953
gland development GO:0048732 48 0.952
Fly
platelet aggregation GO:0070527 32 0.947
purine nucleoside catabolic process GO:0006152 398 0.947
endodermal cell differentiation GO:0035987 31 0.947
regulation of cellular component biogenesis GO:0044087 281 0.946
growth GO:0040007 202 0.946
skin development GO:0043588 76 0.945
regulation of protein localization to plasma membrane GO:1903076 40 0.943
positive regulation of phosphorylation GO:0042327 394 0.941
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 43 0.940
striated muscle tissue development GO:0014706 59 0.937
platelet activation GO:0030168 44 0.937
sensory perception of smell GO:0007608 2 0.937
regulation of anatomical structure morphogenesis GO:0022603 286 0.934
striated muscle cell development GO:0055002 27 0.933
maintenance of location GO:0051235 112 0.932
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.931
regulation of cellular amino acid metabolic process GO:0006521 6 0.930
behavior GO:0007610 112 0.928
Fly
epithelium development GO:0060429 227 0.926
Fly
response to wounding GO:0009611 168 0.925
enzyme linked receptor protein signaling pathway GO:0007167 303 0.924
regulation of establishment of protein localization GO:0070201 242 0.924
regulation of cell morphogenesis GO:0022604 153 0.923
positive regulation of endocytosis GO:0045807 42 0.922
somitogenesis GO:0001756 2 0.922
muscle contraction GO:0006936 73 0.922
actin filament bundle assembly GO:0051017 54 0.921
negative regulation of apoptotic signaling pathway GO:2001234 97 0.919
peptidyl tyrosine modification GO:0018212 170 0.919
cardiovascular system development GO:0072358 262 0.918
intracellular protein transport GO:0006886 270 0.914
positive regulation of cell motility GO:2000147 177 0.914
pericardium development GO:0060039 2 0.912
multicellular organismal aging GO:0010259 3 0.911
Fly
cell junction organization GO:0034330 79 0.910
digestive tract development GO:0048565 75 0.905
sensory perception of chemical stimulus GO:0007606 38 0.904
establishment of protein localization to membrane GO:0090150 121 0.903
positive regulation of developmental process GO:0051094 314 0.900
neuron differentiation GO:0030182 138 0.899
Fly
negative regulation of transport GO:0051051 176 0.898
positive regulation of cellular amine metabolic process GO:0033240 7 0.898
single organism membrane organization GO:0044802 268 0.897
behavioral response to ethanol GO:0048149 2 0.897
Fly
cell projection assembly GO:0030031 126 0.893
renal system development GO:0072001 63 0.892
sarcomere organization GO:0045214 8 0.891
response to hypoxia GO:0001666 96 0.889
membrane organization GO:0061024 292 0.886
calcium ion transport GO:0006816 147 0.885
regulation of cellular amine metabolic process GO:0033238 11 0.882
cellular response to endogenous stimulus GO:0071495 336 0.881
negative regulation of cell motility GO:2000146 104 0.869
digestive system development GO:0055123 75 0.865
formation of primary germ layer GO:0001704 42 0.865
cell part morphogenesis GO:0032990 137 0.864
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.862
Fly
response to decreased oxygen levels GO:0036293 96 0.856
elastic fiber assembly GO:0048251 3 0.855
regulation of purine nucleotide metabolic process GO:1900542 264 0.855
cell adhesion mediated by integrin GO:0033627 27 0.852
vesicle mediated transport GO:0016192 371 0.845
Mouse
regulation of metal ion transport GO:0010959 120 0.838
adenylate cyclase inhibiting dopamine receptor signaling pathway GO:0007195 4 0.838
cation transport GO:0006812 331 0.837
plasma membrane organization GO:0007009 115 0.836
cellular protein complex assembly GO:0043623 188 0.836
axon extension GO:0048675 13 0.831
regulation of actin filament bundle assembly GO:0032231 36 0.831
myosin filament assembly GO:0031034 2 0.830
salivary gland morphogenesis GO:0007435 4 0.827
embryonic morphogenesis GO:0048598 85 0.827
response to transforming growth factor beta GO:0071559 94 0.822
nail development GO:0035878 3 0.822
determination of adult lifespan GO:0008340 2 0.820
Fly
endothelial cell migration GO:0043542 86 0.819
heterotypic cell cell adhesion GO:0034113 28 0.818
calcium ion transmembrane transport GO:0070588 76 0.816
positive regulation of protein phosphorylation GO:0001934 313 0.814
regulation of apoptotic signaling pathway GO:2001233 175 0.811
amine metabolic process GO:0009308 44 0.807
regulation of vesicle mediated transport GO:0060627 130 0.792
epithelial cell development GO:0002064 34 0.790
Fly
granulocyte chemotaxis GO:0071621 37 0.789
adult locomotory behavior GO:0008344 1 0.789
regulation of protein targeting GO:1903533 91 0.788
positive regulation of cellular component movement GO:0051272 181 0.787
substrate adhesion dependent cell spreading GO:0034446 41 0.785
extrinsic apoptotic signaling pathway GO:0097191 119 0.783
thiamine transmembrane transport GO:0071934 2 0.783
actin polymerization or depolymerization GO:0008154 56 0.781
nucleoside triphosphate metabolic process GO:0009141 422 0.777
regulation of protein localization to nucleus GO:1900180 85 0.772
negative regulation of apoptotic process GO:0043066 316 0.769
negative regulation of organelle organization GO:0010639 126 0.765
nuclear migration GO:0007097 1 0.762
regulation of actin filament length GO:0030832 56 0.762
regulation of protein binding GO:0043393 66 0.761
heart development GO:0007507 95 0.760
regulation of cellular component size GO:0032535 82 0.756
neuron projection morphogenesis GO:0048812 50 0.755
Fly
integrin activation GO:0033622 8 0.754
establishment of protein localization to plasma membrane GO:0090002 68 0.753
negative regulation of developmental process GO:0051093 247 0.743
Fly
regulation of lipoprotein metabolic process GO:0050746 7 0.739
wound healing GO:0042060 115 0.734
ectoderm development GO:0007398 3 0.733
cellular macromolecular complex assembly GO:0034622 324 0.733
actin filament polymerization GO:0030041 45 0.730
glycosyl compound catabolic process GO:1901658 413 0.728
blood coagulation GO:0007596 76 0.726
endocytosis GO:0006897 159 0.726
digestive tract morphogenesis GO:0048546 56 0.726
blood vessel development GO:0001568 172 0.716
regulation of mapk cascade GO:0043408 262 0.716
protein import into nucleus GO:0006606 104 0.714
organophosphate catabolic process GO:0046434 430 0.710
regulation of endocytosis GO:0030100 72 0.698
tissue migration GO:0090130 119 0.695
neurological system process GO:0050877 163 0.692
Fly
embryo development GO:0009790 123 0.691
Worm
actin cytoskeleton reorganization GO:0031532 37 0.690
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.687
positive regulation of cytoplasmic transport GO:1903651 82 0.682
positive regulation of protein kinase activity GO:0045860 190 0.681
response to ethanol GO:0045471 11 0.680
Fly
nucleotide catabolic process GO:0009166 408 0.680
positive regulation of cell proliferation GO:0008284 301 0.680
skeletal muscle organ development GO:0060538 26 0.675
regulation of protein polymerization GO:0032271 63 0.674
ion transmembrane transport GO:0034220 338 0.673
cilium morphogenesis GO:0060271 75 0.670
regulation of epithelial cell migration GO:0010632 93 0.667
nucleoside catabolic process GO:0009164 408 0.665
actin crosslink formation GO:0051764 1 0.665
axon development GO:0061564 34 0.662
Fly
cellular potassium ion transport GO:0071804 60 0.661
regulation of actin polymerization or depolymerization GO:0008064 56 0.660
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.658
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.658
actin mediated cell contraction GO:0070252 12 0.658
regulation of actin filament depolymerization GO:0030834 10 0.656
lymphocyte activation GO:0046649 133 0.643
cell substrate adherens junction assembly GO:0007045 30 0.641
collagen metabolic process GO:0032963 28 0.639
activation of mapk activity GO:0000187 45 0.637
purine ribonucleotide catabolic process GO:0009154 404 0.636
regulation of axon extension GO:0030516 7 0.625
neuronal action potential GO:0019228 9 0.622
ribonucleoside triphosphate catabolic process GO:0009203 391 0.622
transmission of nerve impulse GO:0019226 11 0.621
regulation of transcription factor import into nucleus GO:0042990 39 0.617
neuron development GO:0048666 113 0.614
Fly
mitotic nuclear division GO:0007067 119 0.607
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.603
response to abiotic stimulus GO:0009628 336 0.598
cardiac muscle fiber development GO:0048739 4 0.597
striated muscle contraction GO:0006941 52 0.596
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.592
actin filament based movement GO:0030048 17 0.590
positive regulation of protein import into nucleus GO:0042307 46 0.588
muscle cell differentiation GO:0042692 63 0.588
endomembrane system organization GO:0010256 196 0.587
developmental cell growth GO:0048588 18 0.584
positive regulation of protein localization to nucleus GO:1900182 48 0.584
cell cell adhesion mediated by integrin GO:0033631 8 0.584
cell substrate junction assembly GO:0007044 35 0.579
post embryonic organ development GO:0048569 1 0.579
Fly
protein depolymerization GO:0051261 30 0.579
regulation of stress fiber assembly GO:0051492 32 0.567
cellular ketone metabolic process GO:0042180 80 0.566
blood vessel morphogenesis GO:0048514 162 0.562
reproductive process GO:0022414 106 0.561
Worm Fly
gastrulation GO:0007369 51 0.559
cell projection morphogenesis GO:0048858 129 0.554
positive regulation of phagocytosis engulfment GO:0060100 1 0.553
maintenance of location in cell GO:0051651 62 0.551
odontogenesis GO:0042476 25 0.549
regulation of ion transport GO:0043269 189 0.546
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.544
neuron projection extension GO:1990138 14 0.541
morphogenesis of an epithelium GO:0002009 60 0.538
Fly
neutrophil chemotaxis GO:0030593 24 0.537
regulation of growth GO:0040008 165 0.533
pattern specification process GO:0007389 43 0.532
positive regulation of programmed cell death GO:0043068 249 0.528
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 1 0.522
myofibril assembly GO:0030239 10 0.521
movement in host environment GO:0052126 25 0.520
memory GO:0007613 3 0.516
regulation of rho protein signal transduction GO:0035023 79 0.515
neuron projection guidance GO:0097485 12 0.514
Fly
nucleoside phosphate catabolic process GO:1901292 412 0.507
regulation of extent of cell growth GO:0061387 9 0.505
response to mercury ion GO:0046689 4 0.496
regulation of intracellular transport GO:0032386 195 0.490
negative regulation of cell death GO:0060548 345 0.485
hematopoietic or lymphoid organ development GO:0048534 186 0.484
Fly
purine containing compound catabolic process GO:0072523 411 0.481
establishment of protein localization to organelle GO:0072594 172 0.480
purine nucleoside monophosphate metabolic process GO:0009126 186 0.480
myosin filament organization GO:0031033 2 0.479
purine nucleoside triphosphate metabolic process GO:0009144 412 0.473
protein catabolic process GO:0030163 325 0.473
negative regulation of ion transmembrane transport GO:0034766 26 0.469
cell growth GO:0016049 160 0.464
positive regulation of potassium ion transmembrane transporter activity GO:1901018 8 0.462
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.461
extracellular structure organization GO:0043062 41 0.460
Fly
adult behavior GO:0030534 18 0.453
Fly
positive regulation of cell differentiation GO:0045597 211 0.448
ribonucleoside catabolic process GO:0042454 406 0.444
positive regulation of locomotion GO:0040017 186 0.444
regulation of cell adhesion GO:0030155 166 0.444
purine nucleotide catabolic process GO:0006195 405 0.443
muscle tissue development GO:0060537 62 0.437
urogenital system development GO:0001655 65 0.437
nuclear transport GO:0051169 179 0.436
leukocyte tethering or rolling GO:0050901 15 0.435
spindle assembly involved in mitosis GO:0090307 12 0.431
leukocyte migration GO:0050900 107 0.431
regulation of nucleoside metabolic process GO:0009118 209 0.426
protein import GO:0017038 130 0.424
regulation of protein import into nucleus GO:0042306 78 0.419
positive regulation of cell migration GO:0030335 172 0.416
embryo development ending in birth or egg hatching GO:0009792 34 0.415
Worm
skeletal muscle tissue development GO:0007519 24 0.414
atp catabolic process GO:0006200 157 0.414
positive regulation of intracellular protein transport GO:0090316 76 0.412
negative regulation of low density lipoprotein particle receptor biosynthetic process GO:0045715 3 0.411
nucleoside monophosphate metabolic process GO:0009123 191 0.411
regulation of cell growth GO:0001558 135 0.407
mesoderm morphogenesis GO:0048332 11 0.406
cell aging GO:0007569 52 0.400
developmental growth involved in morphogenesis GO:0060560 23 0.399
response to oxygen levels GO:0070482 100 0.396
sprouting angiogenesis GO:0002040 29 0.393
protein targeting GO:0006605 187 0.393
ribonucleoside triphosphate metabolic process GO:0009199 412 0.391
ossification GO:0001503 121 0.377
leukocyte proliferation GO:0070661 74 0.375
regulation of cellular response to growth factor stimulus GO:0090287 76 0.373
positive regulation of intracellular transport GO:0032388 104 0.369
striated muscle myosin thick filament assembly GO:0071688 2 0.365
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.365
multicellular organismal signaling GO:0035637 34 0.362
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.362
mitotic cell cycle process GO:1903047 286 0.356
gtp catabolic process GO:0006184 237 0.356
regulation of protein complex assembly GO:0043254 147 0.355
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.352
uterus morphogenesis GO:0061038 2 0.350
Worm
regulation of membrane potential GO:0042391 95 0.341
purine ribonucleoside metabolic process GO:0046128 437 0.341
negative regulation of protein transport GO:0051224 75 0.339
oocyte differentiation GO:0009994 2 0.338
nuclear division GO:0000280 128 0.336
regulation of potassium ion transmembrane transport GO:1901379 20 0.332
positive regulation of cell substrate adhesion GO:0010811 37 0.331
cytoplasmic sequestering of protein GO:0051220 12 0.328
cytoplasmic transport GO:0016482 379 0.323
negative regulation of protein localization to cell surface GO:2000009 5 0.323
cell cell junction organization GO:0045216 69 0.320
positive regulation of transferase activity GO:0051347 227 0.320
brain development GO:0007420 97 0.318
reproductive structure development GO:0048608 55 0.315
Worm
regulation of nucleotide catabolic process GO:0030811 205 0.313
heart morphogenesis GO:0003007 48 0.311
divalent inorganic cation transport GO:0072511 158 0.309
regulation of anatomical structure size GO:0090066 101 0.307
single organism behavior GO:0044708 28 0.297
Fly
vocalization behavior GO:0071625 11 0.296
purine nucleoside monophosphate catabolic process GO:0009128 158 0.296
lymphocyte proliferation GO:0046651 70 0.294
respiratory system development GO:0060541 22 0.293
positive regulation of transcription factor import into nucleus GO:0042993 25 0.292
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.291
spindle assembly GO:0051225 29 0.286
central nervous system development GO:0007417 123 0.282
nucleocytoplasmic transport GO:0006913 176 0.280
regulation of cell shape GO:0008360 48 0.278
positive regulation of cellular component biogenesis GO:0044089 158 0.277
regulation of cell projection organization GO:0031344 107 0.277
aging GO:0007568 66 0.277
Fly
regulation of nucleotide metabolic process GO:0006140 269 0.277
negative regulation of phosphate metabolic process GO:0045936 267 0.276
establishment or maintenance of cell polarity GO:0007163 31 0.271
regulation of wnt signaling pathway GO:0030111 123 0.270
mesodermal cell differentiation GO:0048333 10 0.266
divalent metal ion transport GO:0070838 152 0.264
cellular response to hypoxia GO:0071456 51 0.264
ras protein signal transduction GO:0007265 73 0.264
mesoderm development GO:0007498 14 0.264
kidney development GO:0001822 53 0.262
regulation of cell development GO:0060284 161 0.260
positive regulation of leukocyte migration GO:0002687 46 0.260
angiogenesis GO:0001525 147 0.260
thiamine transport GO:0015888 3 0.259
heart contraction GO:0060047 62 0.259
apoptotic signaling pathway GO:0097190 268 0.259
nucleoside triphosphate catabolic process GO:0009143 394 0.257
circulatory system process GO:0003013 113 0.254
negative regulation of programmed cell death GO:0043069 321 0.253
anterior posterior axis specification GO:0009948 2 0.252
regulation of protein kinase activity GO:0045859 289 0.248
nucleus localization GO:0051647 1 0.247
morphogenesis of an epithelial sheet GO:0002011 12 0.246
epithelial cell cell adhesion GO:0090136 7 0.241
negative regulation of protein modification process GO:0031400 200 0.236
positive regulation of gtpase activity GO:0043547 166 0.235
purine nucleoside triphosphate catabolic process GO:0009146 392 0.233
positive regulation of cellular catabolic process GO:0031331 284 0.233
establishment of nucleus localization GO:0040023 1 0.230
blood circulation GO:0008015 113 0.230
regulation of cell cycle GO:0051726 393 0.226
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.226
autophagy GO:0006914 88 0.225
regulation of gtpase activity GO:0043087 180 0.225
positive regulation of phagocytosis GO:0050766 15 0.223
negative regulation of protein complex disassembly GO:0043242 20 0.223
single organism reproductive process GO:0044702 98 0.222
Worm Fly
maintenance of protein location in cell GO:0032507 56 0.222
entry into other organism involved in symbiotic interaction GO:0051828 25 0.218
calcium independent cell matrix adhesion GO:0007161 1 0.218
ribonucleoside monophosphate catabolic process GO:0009158 158 0.213
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.213
regulation of vasculogenesis GO:2001212 3 0.212
cytokinesis GO:0000910 96 0.211
cardiac muscle cell differentiation GO:0055007 15 0.210
adherens junction organization GO:0034332 36 0.210
glial cell development GO:0021782 7 0.208
positive regulation of mapk cascade GO:0043410 190 0.207
regulation of cell cell adhesion GO:0022407 57 0.206
posttranscriptional regulation of gene expression GO:0010608 213 0.203
regulation of ras protein signal transduction GO:0046578 155 0.198
positive regulation of apoptotic process GO:0043065 246 0.197
muscle organ morphogenesis GO:0048644 19 0.196
regulation of transporter activity GO:0032409 82 0.196
regulation of binding GO:0051098 111 0.195
regulation of neurogenesis GO:0050767 82 0.194
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.193
protein polymerization GO:0051258 71 0.193
response to oxygen containing compound GO:1901700 369 0.192
Fly
ventricular cardiac muscle cell differentiation GO:0055012 1 0.192
regulation of endothelial cell migration GO:0010594 67 0.191
vasculature development GO:0001944 181 0.188
lung development GO:0030324 20 0.187
positive regulation of ras gtpase activity GO:0032320 117 0.186
respiratory tube development GO:0030323 20 0.185
membrane protein ectodomain proteolysis GO:0006509 33 0.184
cell activation involved in immune response GO:0002263 30 0.183
guanosine containing compound metabolic process GO:1901068 244 0.183
protein targeting to nucleus GO:0044744 104 0.180
regulation of response to wounding GO:1903034 101 0.179
cardiocyte differentiation GO:0035051 23 0.177
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.177
ribonucleotide catabolic process GO:0009261 405 0.175
immune system development GO:0002520 195 0.175
Fly
negative regulation of multicellular organismal process GO:0051241 317 0.175
Fly
monovalent inorganic cation transport GO:0015672 128 0.173
establishment of cell polarity GO:0030010 22 0.173
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.172
granulocyte migration GO:0097530 40 0.171
negative regulation of potassium ion transmembrane transport GO:1901380 5 0.171
negative regulation of cellular component organization GO:0051129 235 0.171
epithelium migration GO:0090132 119 0.170
regulation of kinase activity GO:0043549 314 0.169
lipid localization GO:0010876 106 0.168
activation of protein kinase activity GO:0032147 90 0.167
guanosine containing compound catabolic process GO:1901069 239 0.166

FLNA disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.996
Human
cardiovascular system disease DOID:1287 106 0.983
muscular disease DOID:0080000 114 0.954
Human
kidney disease DOID:557 36 0.836
urinary system disease DOID:18 40 0.836
bone development disease DOID:0080006 55 0.807
Human
bone disease DOID:0080001 88 0.807
Human
connective tissue disease DOID:65 109 0.807
Human
myopathy DOID:423 104 0.730
Human
muscular dystrophy DOID:9884 51 0.730
Human
emery dreifuss muscular dystrophy DOID:11726 6 0.730
muscle tissue disease DOID:66 113 0.730
Human
auditory system disease DOID:2742 53 0.598
sensory system disease DOID:0050155 203 0.598
nervous system disease DOID:863 431 0.598
heart disease DOID:114 68 0.532
cardiomyopathy DOID:0050700 50 0.532
dilated cardiomyopathy DOID:12930 32 0.532
intrinsic cardiomyopathy DOID:0060036 50 0.532
osteochondrodysplasia DOID:2256 35 0.497
Human
autosomal dominant nonsyndromic deafness DOID:0050564 23 0.372
nonsyndromic deafness DOID:0050563 50 0.372
lipodystrophy DOID:811 7 0.313
skin disease DOID:37 33 0.313
integumentary system disease DOID:16 43 0.313