Homo sapiens

260 known processes

DKK1

dickkopf homolog 1 (Xenopus laevis)

(Aliases: SK,DKK-1)

DKK1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
negative regulation of non canonical wnt signaling pathway GO:2000051 1 0.903
forelimb morphogenesis GO:0035136 4 0.661
mammary gland formation GO:0060592 1 0.583
embryonic forelimb morphogenesis GO:0035115 4 0.520
rostrocaudal neural tube patterning GO:0021903 1 0.484
cellular amino acid metabolic process GO:0006520 116 0.480
amine metabolic process GO:0009308 44 0.447
regulation of cellular ketone metabolic process GO:0010565 50 0.444
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.433
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.379
regulation of cellular amino acid metabolic process GO:0006521 6 0.372
embryonic camera type eye development GO:0031076 2 0.351
regulation of cellular amine metabolic process GO:0033238 11 0.338
hindbrain development GO:0030902 3 0.319
positive regulation of cell proliferation GO:0008284 301 0.313
cellular amine metabolic process GO:0044106 41 0.312
cellular ketone metabolic process GO:0042180 80 0.306
hindlimb morphogenesis GO:0035137 2 0.305
positive regulation of cellular amine metabolic process GO:0033240 7 0.301
somatic stem cell division GO:0048103 1 0.263
morphogenesis of embryonic epithelium GO:0016331 4 0.262
forebrain generation of neurons GO:0021872 3 0.260
pericardium development GO:0060039 2 0.245
retina vasculature morphogenesis in camera type eye GO:0061299 3 0.226
mesenchymal cell development GO:0014031 50 0.222
response to organic cyclic compound GO:0014070 204 0.221
regulation of wnt signaling pathway involved in heart development GO:0003307 3 0.216
neural tube patterning GO:0021532 2 0.212
neuroblast proliferation GO:0007405 4 0.201
positive regulation of hyaluronan biosynthetic process GO:1900127 3 0.199
single organismal cell cell adhesion GO:0016337 148 0.197
stem cell division GO:0017145 2 0.195
positive regulation of developmental process GO:0051094 314 0.190
Mouse
somitogenesis GO:0001756 2 0.188
Mouse
axis elongation GO:0003401 4 0.185
negative regulation of cellular protein metabolic process GO:0032269 353 0.185
cerebral cortex cell migration GO:0021795 3 0.184
tube development GO:0035295 125 0.184
epithelium development GO:0060429 227 0.184
Mouse
cell migration involved in gastrulation GO:0042074 1 0.179
ameboidal type cell migration GO:0001667 135 0.178
metal ion transport GO:0030001 272 0.176
ectodermal placode formation GO:0060788 1 0.174
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.167
embryonic epithelial tube formation GO:0001838 4 0.165
cell adhesion GO:0007155 325 0.163
negative regulation of protein metabolic process GO:0051248 391 0.163
negative regulation of striated muscle tissue development GO:0045843 11 0.160
negative regulation of developmental process GO:0051093 247 0.158
transmembrane transport GO:0055085 399 0.158
cerebellum development GO:0021549 2 0.156
ion transmembrane transport GO:0034220 338 0.155
mesenchymal cell differentiation GO:0048762 52 0.155
neuronal stem cell division GO:0036445 1 0.151
cation transport GO:0006812 331 0.150
regulation of cell differentiation GO:0045595 393 0.149
single organism cell adhesion GO:0098602 179 0.148
organ morphogenesis GO:0009887 147 0.142
long term memory GO:0007616 2 0.142
renal system development GO:0072001 63 0.141
organonitrogen compound biosynthetic process GO:1901566 200 0.140
regulation of cardiac muscle tissue development GO:0055024 13 0.140
negative regulation of cell proliferation GO:0008285 228 0.139
chemical homeostasis GO:0048878 306 0.133
urogenital system development GO:0001655 65 0.130
skeletal system development GO:0001501 79 0.130
positive regulation of cell differentiation GO:0045597 211 0.130
Mouse
carbohydrate derivative biosynthetic process GO:1901137 207 0.128
morphogenesis of a polarized epithelium GO:0001738 3 0.128
response to lipid GO:0033993 206 0.127
Mouse
establishment of planar polarity GO:0001736 3 0.126
circulatory system development GO:0072359 262 0.126
neuroblast division GO:0055057 1 0.125
mesenchyme development GO:0060485 59 0.123
biological adhesion GO:0022610 331 0.123
regulation of anatomical structure morphogenesis GO:0022603 286 0.120
ectodermal placode development GO:0071696 1 0.119
digestive tract development GO:0048565 75 0.119
system process GO:0003008 349 0.119
vasculature development GO:0001944 181 0.116
positive regulation of cellular component organization GO:0051130 376 0.115
blood vessel development GO:0001568 172 0.115
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.114
nervous system development GO:0007399 293 0.114
Mouse
peptidyl tyrosine phosphorylation GO:0018108 170 0.112
metencephalon development GO:0022037 2 0.111
positive regulation of protein phosphorylation GO:0001934 313 0.111
cellular component morphogenesis GO:0032989 314 0.111
Mouse
anatomical structure formation involved in morphogenesis GO:0048646 284 0.110
cell development GO:0048468 328 0.109
Mouse
cellular response to oxygen containing compound GO:1901701 276 0.108
carbohydrate metabolic process GO:0005975 207 0.107
ectodermal placode morphogenesis GO:0071697 1 0.106
regulation of kinase activity GO:0043549 314 0.104
positive regulation of hydrolase activity GO:0051345 331 0.103
positive regulation of canonical wnt signaling pathway GO:0090263 33 0.101
Human
post embryonic development GO:0009791 2 0.100
negative regulation of cell death GO:0060548 345 0.100
regulation of cell development GO:0060284 161 0.099
regulation of mapk cascade GO:0043408 262 0.098
anterior posterior axis specification GO:0009948 2 0.097
embryonic camera type eye morphogenesis GO:0048596 2 0.096
secretion GO:0046903 254 0.096
regulation of cellular component movement GO:0051270 334 0.096
cellular response to endogenous stimulus GO:0071495 336 0.095
regulation of transferase activity GO:0051338 355 0.093
memory GO:0007613 3 0.093
angiogenesis GO:0001525 147 0.092
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.092
negative regulation of apoptotic process GO:0043066 316 0.092
positive regulation of organelle organization GO:0010638 195 0.090
mucopolysaccharide metabolic process GO:1903510 27 0.090
metal ion homeostasis GO:0055065 169 0.090
positive regulation of apoptotic process GO:0043065 246 0.089
regulation of cell proliferation involved in heart morphogenesis GO:2000136 1 0.089
primary neural tube formation GO:0014020 3 0.089
positive regulation of transport GO:0051050 336 0.088
positive regulation of kinase activity GO:0033674 204 0.088
mapk cascade GO:0000165 288 0.087
embryonic hindlimb morphogenesis GO:0035116 2 0.087
cardiovascular system development GO:0072358 262 0.087
ventricular septum morphogenesis GO:0060412 3 0.087
positive regulation of map kinase activity GO:0043406 80 0.087
negative regulation of protein modification process GO:0031400 200 0.087
regulation of heart morphogenesis GO:2000826 4 0.086
Mouse
positive regulation of cell motility GO:2000147 177 0.086
negative regulation of wnt signaling pathway GO:0030178 69 0.084
peptidyl tyrosine modification GO:0018212 170 0.084
cellular response to organic cyclic compound GO:0071407 127 0.084
regulation of cell motility GO:2000145 299 0.082
blood vessel morphogenesis GO:0048514 162 0.081
positive regulation of phosphorylation GO:0042327 394 0.080
muscle structure development GO:0061061 98 0.079
negative regulation of transport GO:0051051 176 0.079
regulation of cell cycle GO:0051726 393 0.079
single organism carbohydrate metabolic process GO:0044723 193 0.079
positive regulation of programmed cell death GO:0043068 249 0.078
enzyme linked receptor protein signaling pathway GO:0007167 303 0.078
regulation of cell cycle process GO:0010564 266 0.078
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.077
canonical wnt signaling pathway GO:0060070 116 0.077
cell proliferation involved in heart morphogenesis GO:0061323 1 0.077
retina vasculature development in camera type eye GO:0061298 3 0.077
regulation of protein localization GO:0032880 296 0.077
embryonic eye morphogenesis GO:0048048 2 0.077
tube closure GO:0060606 3 0.076
erk1 and erk2 cascade GO:0070371 104 0.076
embryonic morphogenesis GO:0048598 85 0.075
negative regulation of protein phosphorylation GO:0001933 140 0.075
hematopoietic or lymphoid organ development GO:0048534 186 0.075
response to hormone GO:0009725 175 0.075
positive regulation of cell death GO:0010942 263 0.075
small gtpase mediated signal transduction GO:0007264 78 0.075
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.074
lipid transport GO:0006869 90 0.074
regulation of cell migration GO:0030334 289 0.074
tube morphogenesis GO:0035239 95 0.074
thalamus development GO:0021794 2 0.074
positive regulation of mapk cascade GO:0043410 190 0.074
mitotic cell cycle GO:0000278 326 0.074
digestive system development GO:0055123 75 0.074
epithelial to mesenchymal transition GO:0001837 48 0.073
regulation of locomotion GO:0040012 329 0.072
positive regulation of locomotion GO:0040017 186 0.072
mammary gland morphogenesis GO:0060443 2 0.071
ion homeostasis GO:0050801 230 0.071
stem cell development GO:0048864 69 0.070
regulation of cellular component biogenesis GO:0044087 281 0.070
divalent inorganic cation homeostasis GO:0072507 136 0.070
embryonic retina morphogenesis in camera type eye GO:0060059 1 0.070
regulation of secretion GO:0051046 194 0.069
central nervous system development GO:0007417 123 0.069
Mouse
regulation of map kinase activity GO:0043405 108 0.069
negative regulation of cell differentiation GO:0045596 171 0.069
cation homeostasis GO:0055080 189 0.069
regulation of polysaccharide biosynthetic process GO:0032885 20 0.069
branching morphogenesis of an epithelial tube GO:0048754 19 0.069
cardiac chamber development GO:0003205 30 0.069
sterol homeostasis GO:0055092 28 0.069
positive regulation of mitosis GO:0045840 25 0.068
protein localization to organelle GO:0033365 280 0.068
retinal blood vessel morphogenesis GO:0061304 2 0.068
vesicle mediated transport GO:0016192 371 0.067
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.067
regulation of carbohydrate metabolic process GO:0006109 54 0.067
segmentation GO:0035282 4 0.066
Mouse
negative regulation of phosphorylation GO:0042326 174 0.065
regulation of wnt signaling pathway planar cell polarity pathway GO:2000095 2 0.065
cellular divalent inorganic cation homeostasis GO:0072503 128 0.065
positive regulation of transferase activity GO:0051347 227 0.065
cell division GO:0051301 168 0.065
cellular response to lipid GO:0071396 127 0.065
non canonical wnt signaling pathway GO:0035567 14 0.064
immune system development GO:0002520 195 0.064
negative regulation of wnt signaling pathway involved in heart development GO:0003308 2 0.064
negative regulation of phosphorus metabolic process GO:0010563 267 0.064
regulation of epithelial cell migration GO:0010632 93 0.064
positive regulation of protein tyrosine kinase activity GO:0061098 24 0.063
divalent metal ion transport GO:0070838 152 0.062
regulation of proteolysis GO:0030162 293 0.062
cell morphogenesis GO:0000902 296 0.062
Mouse
response to abiotic stimulus GO:0009628 336 0.061
regulation of protein transport GO:0051223 213 0.061
regulation of ion transport GO:0043269 189 0.061
morphogenesis of a branching structure GO:0001763 21 0.061
circulatory system process GO:0003013 113 0.060
response to oxygen containing compound GO:1901700 369 0.060
Mouse
epithelial cell proliferation GO:0050673 128 0.059
regulation of protein kinase activity GO:0045859 289 0.059
lipid biosynthetic process GO:0008610 177 0.059
single organism cellular localization GO:1902580 332 0.059
negative regulation of phosphate metabolic process GO:0045936 267 0.058
positive regulation of protein transport GO:0051222 135 0.058
regulation of striated muscle tissue development GO:0016202 26 0.058
endothelial cell migration GO:0043542 86 0.058
cardiac muscle tissue development GO:0048738 39 0.057
cartilage morphogenesis GO:0060536 1 0.057
generation of neurons GO:0048699 152 0.057
cholesterol homeostasis GO:0042632 28 0.057
negative regulation of muscle organ development GO:0048635 12 0.056
cellular metal ion homeostasis GO:0006875 146 0.056
regulation of protein serine threonine kinase activity GO:0071900 179 0.056
cellular homeostasis GO:0019725 196 0.056
growth GO:0040007 202 0.056
regulation of epithelial cell proliferation GO:0050678 113 0.056
heart morphogenesis GO:0003007 48 0.056
calcium ion homeostasis GO:0055074 122 0.055
sterol transport GO:0015918 39 0.055
divalent inorganic cation transport GO:0072511 158 0.054
brain development GO:0007420 97 0.054
Mouse
morphogenesis of an epithelium GO:0002009 60 0.054
midbrain development GO:0030901 45 0.054
convergent extension GO:0060026 1 0.054
response to organonitrogen compound GO:0010243 156 0.053
odontogenesis GO:0042476 25 0.053
toxin transport GO:1901998 4 0.052
response to acid chemical GO:0001101 66 0.052
Mouse
signal transduction by phosphorylation GO:0023014 297 0.052
osteoblast differentiation GO:0001649 92 0.052
negative regulation of canonical wnt signaling pathway GO:0090090 55 0.052
regulation of plasma lipoprotein particle levels GO:0097006 32 0.052
regulation of wnt signaling pathway GO:0030111 123 0.052
protein maturation GO:0051604 233 0.051
peptidyl threonine modification GO:0018210 45 0.051
protein targeting GO:0006605 187 0.051
lipid metabolic process GO:0006629 381 0.051
head development GO:0060322 108 0.051
Mouse
regulation of homeostatic process GO:0032844 121 0.050
regulation of nucleotide metabolic process GO:0006140 269 0.050
nuclear transport GO:0051169 179 0.050
cardiac chamber morphogenesis GO:0003206 26 0.049
cell type specific apoptotic process GO:0097285 125 0.049
positive regulation of protein kinase activity GO:0045860 190 0.049
regulation of intracellular protein transport GO:0033157 123 0.049
mitotic cell cycle process GO:1903047 286 0.049
cartilage development GO:0051216 31 0.049
regulation of mitosis GO:0007088 63 0.048
regulation of nuclear division GO:0051783 65 0.048
blood circulation GO:0008015 113 0.048
regulation of muscle tissue development GO:1901861 26 0.048
aminoglycan metabolic process GO:0006022 39 0.048
cellular ion homeostasis GO:0006873 168 0.048
stem cell differentiation GO:0048863 93 0.048
positive regulation of nucleotide metabolic process GO:0045981 230 0.048
cell morphogenesis involved in differentiation GO:0000904 144 0.048
Mouse
secretion by cell GO:0032940 226 0.048
epithelium migration GO:0090132 119 0.047
tissue morphogenesis GO:0048729 96 0.047
response to biotic stimulus GO:0009607 276 0.047
nucleocytoplasmic transport GO:0006913 176 0.047
regulation of cytokine production GO:0001817 232 0.047
positive regulation of cell cycle process GO:0090068 106 0.047
skeletal system morphogenesis GO:0048705 24 0.046
inner ear morphogenesis GO:0042472 4 0.046
protein localization to nucleus GO:0034504 136 0.046
regulation of transmembrane transport GO:0034762 139 0.046
cellular chemical homeostasis GO:0055082 180 0.045
cellular response to growth factor stimulus GO:0071363 197 0.045
neuron differentiation GO:0030182 138 0.045
negative regulation of secretion GO:0051048 58 0.045
regulation of endopeptidase activity GO:0052548 170 0.045
cellular lipid metabolic process GO:0044255 303 0.045
response to nitrogen compound GO:1901698 184 0.044
locomotory behavior GO:0007626 1 0.044
positive regulation of intracellular protein transport GO:0090316 76 0.044
embryonic digit morphogenesis GO:0042733 6 0.043
negative regulation of catalytic activity GO:0043086 335 0.043
neural tube closure GO:0001843 3 0.043
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.043
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.043
neurogenesis GO:0022008 169 0.043
wnt signaling pathway GO:0016055 156 0.043
negative regulation of epithelial cell proliferation GO:0050680 48 0.042
hair follicle morphogenesis GO:0031069 2 0.042
hexose catabolic process GO:0019320 7 0.042
regulation of cell morphogenesis GO:0022604 153 0.042
ribonucleoside triphosphate catabolic process GO:0009203 391 0.042
heart development GO:0007507 95 0.042
cellular cation homeostasis GO:0030003 163 0.041
cytoplasmic transport GO:0016482 379 0.041
defense response GO:0006952 315 0.041
positive regulation of catabolic process GO:0009896 310 0.041
cytokine production GO:0001816 247 0.041
response to wounding GO:0009611 168 0.041
multicellular organismal aging GO:0010259 3 0.041
immune response GO:0006955 307 0.041
carbohydrate biosynthetic process GO:0016051 42 0.040
monosaccharide metabolic process GO:0005996 74 0.040
single organism carbohydrate catabolic process GO:0044724 33 0.040
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.040
glycosyl compound catabolic process GO:1901658 413 0.040
negative regulation of programmed cell death GO:0043069 321 0.040
nucleoside triphosphate metabolic process GO:0009141 422 0.040
purine nucleoside triphosphate metabolic process GO:0009144 412 0.040
gastrulation GO:0007369 51 0.040
organelle fission GO:0048285 149 0.039
cellular macromolecular complex assembly GO:0034622 324 0.039
cholesterol transport GO:0030301 39 0.039
positive regulation of cell division GO:0051781 59 0.039
regulation of protein import into nucleus GO:0042306 78 0.039
negative regulation of cellular component organization GO:0051129 235 0.039
purine ribonucleoside metabolic process GO:0046128 437 0.039
establishment of protein localization to organelle GO:0072594 172 0.039
positive regulation of cell development GO:0010720 92 0.039
negative regulation of transferase activity GO:0051348 124 0.039
response to cytokine GO:0034097 232 0.038
single organism membrane organization GO:0044802 268 0.038
cellular macromolecule catabolic process GO:0044265 380 0.038
neurological system process GO:0050877 163 0.038
negative regulation of multicellular organismal process GO:0051241 317 0.038
regulation of cellular response to stress GO:0080135 244 0.038
membrane organization GO:0061024 292 0.038
determination of adult lifespan GO:0008340 2 0.038
kidney development GO:0001822 53 0.038
actin filament based process GO:0030029 224 0.037
regulation of nervous system development GO:0051960 88 0.037
female gamete generation GO:0007292 2 0.037
regulation of intracellular transport GO:0032386 195 0.037
response to alcohol GO:0097305 64 0.037
peptidyl threonine phosphorylation GO:0018107 41 0.037
nuclear division GO:0000280 128 0.037
positive regulation of cellular component movement GO:0051272 181 0.037
neural crest cell development GO:0014032 3 0.037
mitotic nuclear division GO:0007067 119 0.037
negative regulation of locomotion GO:0040013 118 0.036
aminoglycan biosynthetic process GO:0006023 29 0.036
digestive tract morphogenesis GO:0048546 56 0.036
cell activation GO:0001775 213 0.036
regulation of cytoplasmic transport GO:1903649 149 0.036
plasma lipoprotein particle clearance GO:0034381 16 0.036
regulation of nucleocytoplasmic transport GO:0046822 98 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
ribonucleotide catabolic process GO:0009261 405 0.036
nucleoside catabolic process GO:0009164 408 0.036
cardiocyte differentiation GO:0035051 23 0.036
purine ribonucleotide catabolic process GO:0009154 404 0.036
limb morphogenesis GO:0035108 16 0.036
Mouse
hexose metabolic process GO:0019318 55 0.035
calcium ion import GO:0070509 23 0.035
polysaccharide biosynthetic process GO:0000271 27 0.035
epithelial tube morphogenesis GO:0060562 38 0.034
ras protein signal transduction GO:0007265 73 0.034
regulation of protein targeting GO:1903533 91 0.034
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.034
wound healing GO:0042060 115 0.034
lipid homeostasis GO:0055088 39 0.034
neuron fate commitment GO:0048663 2 0.034
regulation of protein localization to nucleus GO:1900180 85 0.034
trachea development GO:0060438 1 0.034
epithelial cell migration GO:0010631 119 0.033
canonical wnt signaling pathway involved in cardiac muscle cell fate commitment GO:0061317 3 0.033
positive regulation of homeostatic process GO:0032846 47 0.033
protein import GO:0017038 130 0.033
nucleoside triphosphate catabolic process GO:0009143 394 0.033
positive regulation of intracellular transport GO:0032388 104 0.033
morphogenesis of a branching epithelium GO:0061138 20 0.033
negative regulation of hydrolase activity GO:0051346 182 0.033
single organism nuclear import GO:1902593 104 0.033
negative regulation of kinase activity GO:0033673 106 0.033
anatomical structure homeostasis GO:0060249 100 0.033
multicellular organismal homeostasis GO:0048871 67 0.033
intracellular protein transport GO:0006886 270 0.032
positive regulation of immune system process GO:0002684 283 0.032
regulation of canonical wnt signaling pathway GO:0060828 88 0.032
appendage morphogenesis GO:0035107 16 0.032
Mouse
neuron development GO:0048666 113 0.032
bone development GO:0060348 26 0.032
regulation of cell division GO:0051302 116 0.032
positive regulation of wnt signaling pathway GO:0030177 54 0.032
Human
cyclic nucleotide metabolic process GO:0009187 82 0.031
nucleoside phosphate catabolic process GO:1901292 412 0.031
positive regulation of cell migration GO:0030335 172 0.031
apoptotic signaling pathway GO:0097190 268 0.031
epidermis morphogenesis GO:0048730 3 0.031
protein targeting to nucleus GO:0044744 104 0.031
positive regulation of mitotic cell cycle GO:0045931 60 0.031
taxis GO:0042330 157 0.031
regulation of peptidase activity GO:0052547 180 0.031
pituitary gland development GO:0021983 2 0.031
carbohydrate catabolic process GO:0016052 36 0.031
cardiac atrium morphogenesis GO:0003209 7 0.031
small molecule biosynthetic process GO:0044283 157 0.031
positive regulation of gtpase activity GO:0043547 166 0.030
regulation of osteoblast differentiation GO:0045667 38 0.030
reproductive process GO:0022414 106 0.030
regulation of fat cell differentiation GO:0045598 23 0.030
embryo development GO:0009790 123 0.030
regulation of gtp catabolic process GO:0033124 180 0.030
lysosomal transport GO:0007041 33 0.030
morphogenesis of an epithelial sheet GO:0002011 12 0.030
protein processing GO:0016485 226 0.030
regulation of gtpase activity GO:0043087 180 0.030
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.029
negative regulation of protein kinase activity GO:0006469 98 0.029
positive regulation of proteolysis GO:0045862 142 0.029
striated muscle tissue development GO:0014706 59 0.029
muscle organ development GO:0007517 56 0.029
regeneration GO:0031099 4 0.029
positive regulation of gtp catabolic process GO:0033126 166 0.029
response to other organism GO:0051707 261 0.029
forebrain regionalization GO:0021871 3 0.029
dopaminergic neuron differentiation GO:0071542 1 0.029
hemopoiesis GO:0030097 180 0.029
organic hydroxy compound metabolic process GO:1901615 147 0.028
regulation of establishment of protein localization GO:0070201 242 0.028
purine containing compound catabolic process GO:0072523 411 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
regulation of response to external stimulus GO:0032101 222 0.028
cartilage condensation GO:0001502 1 0.028
positive regulation of behavior GO:0048520 60 0.028
appendage development GO:0048736 23 0.028
Mouse
oocyte development GO:0048599 1 0.028
protein import into nucleus GO:0006606 104 0.028
cellular response to dna damage stimulus GO:0006974 379 0.028
tissue migration GO:0090130 119 0.028
ossification GO:0001503 121 0.028
Rat
negative regulation of cellular amine metabolic process GO:0033239 3 0.028
positive regulation of carbohydrate metabolic process GO:0045913 21 0.027
single organism reproductive process GO:0044702 98 0.027
chemotaxis GO:0006935 157 0.027
low density lipoprotein particle clearance GO:0034383 8 0.027
cardiac atrium development GO:0003230 10 0.027
regulation of epidermal growth factor activated receptor activity GO:0007176 14 0.027
alcohol metabolic process GO:0006066 114 0.027
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.027
embryonic appendage morphogenesis GO:0035113 9 0.027
Mouse
cell fate determination GO:0001709 3 0.027
positive regulation of keratinocyte migration GO:0051549 4 0.027
cardiac muscle cell contraction GO:0086003 4 0.027
regulation of hormone levels GO:0010817 125 0.026
chordate embryonic development GO:0043009 34 0.026
Mouse
positive regulation of protein import into nucleus GO:0042307 46 0.026
endomembrane system organization GO:0010256 196 0.026
negative regulation of cell growth GO:0030308 83 0.026
canonical wnt signaling pathway involved in regulation of cell proliferation GO:0044340 2 0.026
stress activated protein kinase signaling cascade GO:0031098 94 0.026
regulation of nucleotide catabolic process GO:0030811 205 0.026
glycosaminoglycan metabolic process GO:0030203 35 0.026
positive regulation of cytoplasmic transport GO:1903651 82 0.026
regulation of blood pressure GO:0008217 30 0.026
peptidyl serine modification GO:0018209 106 0.025
oxidation reduction process GO:0055114 396 0.025
tissue homeostasis GO:0001894 63 0.025
limb development GO:0060173 23 0.025
Mouse
regulation of polysaccharide metabolic process GO:0032881 21 0.025
response to external biotic stimulus GO:0043207 261 0.025
regulation of vasculature development GO:1901342 97 0.025
canonical wnt signaling pathway involved in negative regulation of apoptotic process GO:0044336 2 0.025
gland development GO:0048732 48 0.025
adipose tissue development GO:0060612 2 0.025
behavior GO:0007610 112 0.025
regulation of mitotic cell cycle GO:0007346 189 0.024
leukocyte activation GO:0045321 164 0.024
regulation of dermatome development GO:0061183 3 0.024
regulation of apoptotic signaling pathway GO:2001233 175 0.024
reactive oxygen species metabolic process GO:0072593 75 0.024
nerve development GO:0021675 4 0.024
regulation of protein processing GO:0070613 150 0.024
regulation of wnt signaling pathway involved in dorsal ventral axis specification GO:2000053 3 0.024
negative regulation of cellular component movement GO:0051271 106 0.024
regulation of stress activated mapk cascade GO:0032872 84 0.024
neuromuscular junction development GO:0007528 3 0.024
limbic system development GO:0021761 3 0.024
cell aggregation GO:0098743 1 0.024
positive regulation of cellular component biogenesis GO:0044089 158 0.024
response to extracellular stimulus GO:0009991 85 0.024
regulation of reactive oxygen species metabolic process GO:2000377 41 0.024
photoreceptor cell differentiation GO:0046530 2 0.024

DKK1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.039
sensory system disease DOID:0050155 203 0.030
nervous system disease DOID:863 431 0.030
eye and adnexa disease DOID:1492 150 0.026
bone disease DOID:0080001 88 0.025
connective tissue disease DOID:65 109 0.025
eye disease DOID:5614 149 0.024