Homo sapiens

81 known processes

DERL2

Der1-like domain family, member 2

(Aliases: F-LAN-1,FLANa,F-LANa)

DERL2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
modification dependent protein catabolic process GO:0019941 209 0.197
cellular macromolecule catabolic process GO:0044265 380 0.180
ubiquitin dependent protein catabolic process GO:0006511 206 0.143
cellular protein catabolic process GO:0044257 261 0.123
protein catabolic process GO:0030163 325 0.113
modification dependent macromolecule catabolic process GO:0043632 212 0.112
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.099
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.098
glycoprotein biosynthetic process GO:0009101 91 0.096
Human
proteasomal protein catabolic process GO:0010498 176 0.089
carbohydrate derivative biosynthetic process GO:1901137 207 0.074
Human
single organism carbohydrate metabolic process GO:0044723 193 0.071
Human
negative regulation of acute inflammatory response GO:0002674 3 0.063
post embryonic development GO:0009791 2 0.062
reactive nitrogen species metabolic process GO:2001057 3 0.055
cytoplasmic transport GO:0016482 379 0.052
reactive oxygen species metabolic process GO:0072593 75 0.047
response to biotic stimulus GO:0009607 276 0.044
Fly
regulation of acute inflammatory response to antigenic stimulus GO:0002864 1 0.044
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.043
ribonucleoside triphosphate metabolic process GO:0009199 412 0.043
immune response GO:0006955 307 0.043
purine ribonucleoside catabolic process GO:0046130 398 0.041
response to unfolded protein GO:0006986 24 0.041
intracellular protein transport GO:0006886 270 0.040
protein localization to organelle GO:0033365 280 0.038
purine ribonucleoside metabolic process GO:0046128 437 0.035
protein glycosylation GO:0006486 62 0.034
Human
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.034
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.034
vesicle mediated transport GO:0016192 371 0.033
glycoprotein metabolic process GO:0009100 110 0.033
Human
negative regulation of cell death GO:0060548 345 0.032
multicellular organismal aging GO:0010259 3 0.032
cellular response to topologically incorrect protein GO:0035967 19 0.032
single organism cellular localization GO:1902580 332 0.031
cellular response to oxidative stress GO:0034599 85 0.031
determination of adult lifespan GO:0008340 2 0.031
negative regulation of intracellular signal transduction GO:1902532 183 0.030
purine nucleoside catabolic process GO:0006152 398 0.030
oogenesis GO:0048477 2 0.030
nucleoside phosphate catabolic process GO:1901292 412 0.029
response to endoplasmic reticulum stress GO:0034976 49 0.029
cation transport GO:0006812 331 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
response to external biotic stimulus GO:0043207 261 0.029
Fly
nucleoside catabolic process GO:0009164 408 0.028
ribonucleoside triphosphate catabolic process GO:0009203 391 0.028
ribonucleoside catabolic process GO:0042454 406 0.028
organophosphate catabolic process GO:0046434 430 0.028
female gamete generation GO:0007292 2 0.027
carbohydrate metabolic process GO:0005975 207 0.027
Human
nucleoside triphosphate catabolic process GO:0009143 394 0.027
purine containing compound catabolic process GO:0072523 411 0.027
purine ribonucleotide catabolic process GO:0009154 404 0.026
gtp metabolic process GO:0046039 239 0.026
regulation of reactive oxygen species metabolic process GO:2000377 41 0.026
lipid metabolic process GO:0006629 381 0.025
purine nucleotide catabolic process GO:0006195 405 0.025
i kappab kinase nf kappab signaling GO:0007249 166 0.025
glycosyl compound catabolic process GO:1901658 413 0.025
regulation of response to external stimulus GO:0032101 222 0.025
cellular response to dna damage stimulus GO:0006974 379 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
intrinsic apoptotic signaling pathway GO:0097193 127 0.025
regulation of cellular amino acid metabolic process GO:0006521 6 0.025
dephosphorylation GO:0016311 209 0.025
maintenance of location GO:0051235 112 0.024
single organism membrane organization GO:0044802 268 0.024
nucleotide catabolic process GO:0009166 408 0.024
protein n linked glycosylation via asparagine GO:0018279 10 0.024
Human
inflammatory response to antigenic stimulus GO:0002437 4 0.024
hindbrain development GO:0030902 3 0.024
cellular macromolecular complex assembly GO:0034622 324 0.024
gtp catabolic process GO:0006184 237 0.023
negative regulation of apoptotic process GO:0043066 316 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
negative regulation of immune system process GO:0002683 136 0.023
nucleoside triphosphate metabolic process GO:0009141 422 0.023
negative regulation of programmed cell death GO:0043069 321 0.023
response to oxygen containing compound GO:1901700 369 0.023
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.022
guanosine containing compound metabolic process GO:1901068 244 0.022
guanosine containing compound catabolic process GO:1901069 239 0.022
ras protein signal transduction GO:0007265 73 0.022
negative regulation of myeloid cell apoptotic process GO:0033033 4 0.022
nitrogen compound transport GO:0071705 191 0.022
protein targeting GO:0006605 187 0.022
locomotory behavior GO:0007626 1 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
regulation of cellular response to stress GO:0080135 244 0.022
cellular response to molecule of bacterial origin GO:0071219 62 0.022
positive regulation of hydrolase activity GO:0051345 331 0.021
response to other organism GO:0051707 261 0.021
Fly
regulation of defense response GO:0031347 154 0.021
endoplasmic reticulum unfolded protein response GO:0030968 16 0.021
secretion by cell GO:0032940 226 0.021
negative regulation of catalytic activity GO:0043086 335 0.021
cellular amino acid metabolic process GO:0006520 116 0.020
cellular amine metabolic process GO:0044106 41 0.020
cellular ketone metabolic process GO:0042180 80 0.020
transmembrane transport GO:0055085 399 0.020
negative regulation of response to external stimulus GO:0032102 83 0.020
response to oxidative stress GO:0006979 121 0.019
amine metabolic process GO:0009308 44 0.019
regulation of cellular amine metabolic process GO:0033238 11 0.019
response to topologically incorrect protein GO:0035966 29 0.019
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.019
response to bacterium GO:0009617 144 0.019
Fly
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
response to lipid GO:0033993 206 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.018
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.018
organelle assembly GO:0070925 176 0.018
mitotic cell cycle GO:0000278 326 0.018
negative regulation of response to wounding GO:1903035 47 0.018
regulation of cellular component movement GO:0051270 334 0.018
regulation of protein transport GO:0051223 213 0.018
membrane organization GO:0061024 292 0.018
metal ion transport GO:0030001 272 0.018
regulation of immune response GO:0050776 201 0.018
cellular lipid metabolic process GO:0044255 303 0.018
regulation of protein localization GO:0032880 296 0.018
er nucleus signaling pathway GO:0006984 23 0.017
regulation of transferase activity GO:0051338 355 0.017
adult locomotory behavior GO:0008344 1 0.017
divalent inorganic cation transport GO:0072511 158 0.017
small gtpase mediated signal transduction GO:0007264 78 0.017
spermatid development GO:0007286 4 0.017
inflammatory cell apoptotic process GO:0006925 3 0.016
regulation of gtpase activity GO:0043087 180 0.016
maintenance of location in cell GO:0051651 62 0.016
microtubule based process GO:0007017 210 0.016
regulation of response to wounding GO:1903034 101 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.015
actin filament based process GO:0030029 224 0.015
segmentation GO:0035282 4 0.015
defense response GO:0006952 315 0.015
Fly
cell projection organization GO:0030030 252 0.015
positive regulation of transport GO:0051050 336 0.015
response to wounding GO:0009611 168 0.015
establishment of protein localization to organelle GO:0072594 172 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
cellular homeostasis GO:0019725 196 0.015
regulation of peptide transport GO:0090087 62 0.014
chromatin organization GO:0006325 351 0.014
cell morphogenesis GO:0000902 296 0.014
cellular response to unfolded protein GO:0034620 16 0.014
regulation of nucleotide metabolic process GO:0006140 269 0.014
regulation of purine nucleotide catabolic process GO:0033121 205 0.014
regulation of apoptotic signaling pathway GO:2001233 175 0.014
protein maturation GO:0051604 233 0.014
spermatid differentiation GO:0048515 4 0.014
cellular protein complex assembly GO:0043623 188 0.014
anterior posterior axis specification GO:0009948 2 0.014
regulation of intracellular transport GO:0032386 195 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
protein ubiquitination GO:0016567 314 0.014
positive regulation of catabolic process GO:0009896 310 0.014
regulation of cell motility GO:2000145 299 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
regulation of binding GO:0051098 111 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
chromatin modification GO:0016568 298 0.013
positive regulation of cellular amine metabolic process GO:0033240 7 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
golgi vesicle transport GO:0048193 80 0.013
negative regulation of cellular protein metabolic process GO:0032269 353 0.013
inflammatory response GO:0006954 79 0.013
cell type specific apoptotic process GO:0097285 125 0.013
biological adhesion GO:0022610 331 0.013
regulation of protein modification by small protein conjugation or removal GO:1903320 107 0.013
regulation of establishment of protein localization GO:0070201 242 0.013
chromosome segregation GO:0007059 114 0.013
regulation of proteolysis GO:0030162 293 0.013
positive regulation of cellular catabolic process GO:0031331 284 0.013
cell development GO:0048468 328 0.013
rna processing GO:0006396 255 0.013
negative regulation of transport GO:0051051 176 0.013
positive regulation of cell death GO:0010942 263 0.013
protein dna complex subunit organization GO:0071824 80 0.013
protein n linked glycosylation GO:0006487 23 0.013
Human
nucleocytoplasmic transport GO:0006913 176 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
cellular response to lipopolysaccharide GO:0071222 57 0.013
regulation of purine nucleotide metabolic process GO:1900542 264 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
compound eye development GO:0048749 1 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.013
cerebellum development GO:0021549 2 0.013
system process GO:0003008 349 0.012
nuclear import GO:0051170 106 0.012
inorganic ion transmembrane transport GO:0098660 231 0.012
regulation of locomotion GO:0040012 329 0.012
cellular component morphogenesis GO:0032989 314 0.012
protein modification by small protein conjugation GO:0032446 342 0.012
acute inflammatory response to antigenic stimulus GO:0002438 1 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
protein localization to nucleus GO:0034504 136 0.012
negative regulation of phosphate metabolic process GO:0045936 267 0.012
secretion GO:0046903 254 0.012
negative regulation of leukocyte apoptotic process GO:2000107 16 0.012
negative regulation of nitric oxide synthase biosynthetic process GO:0051771 3 0.012
regeneration GO:0031099 4 0.012
memory GO:0007613 3 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
rho protein signal transduction GO:0007266 26 0.012
innate immune response GO:0045087 178 0.012
response to starvation GO:0042594 59 0.012
neurological system process GO:0050877 163 0.012
cellular response to lipid GO:0071396 127 0.012
metal ion homeostasis GO:0055065 169 0.012
mitotic cell cycle process GO:1903047 286 0.012
positive regulation of nucleotide metabolic process GO:0045981 230 0.012
regulation of protein catabolic process GO:0042176 155 0.012
ion homeostasis GO:0050801 230 0.012
positive regulation of immune system process GO:0002684 283 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
regulation of cell migration GO:0030334 289 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
protein import GO:0017038 130 0.011
establishment of protein localization to membrane GO:0090150 121 0.011
protein oligomerization GO:0051259 173 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
regulation of cytokine production GO:0001817 232 0.011
rna interference GO:0016246 4 0.011
response to fungus GO:0009620 4 0.011
chemical homeostasis GO:0048878 306 0.011
histone modification GO:0016570 251 0.011
cellular chemical homeostasis GO:0055082 180 0.011
negative regulation of cellular amine metabolic process GO:0033239 3 0.011
regulation of protein complex assembly GO:0043254 147 0.011
oocyte development GO:0048599 1 0.011
negative regulation of protein metabolic process GO:0051248 391 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
protein localization to membrane GO:0072657 160 0.011
sequestering of metal ion GO:0051238 24 0.011
metencephalon development GO:0022037 2 0.011
covalent chromatin modification GO:0016569 254 0.011
regulation of cell differentiation GO:0045595 393 0.011
protein processing GO:0016485 226 0.011
autophagy GO:0006914 88 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
response to molecule of bacterial origin GO:0002237 82 0.011
regulation of cell cycle GO:0051726 393 0.011
protein import into nucleus GO:0006606 104 0.011
positive regulation of locomotion GO:0040017 186 0.011
retrograde protein transport er to cytosol GO:0030970 5 0.011
oocyte differentiation GO:0009994 2 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
cellular response to cytokine stimulus GO:0071345 181 0.010
positive regulation of cellular component movement GO:0051272 181 0.010
divalent metal ion transport GO:0070838 152 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
macromolecule glycosylation GO:0043413 63 0.010
Human
positive regulation of nucleoside metabolic process GO:0045979 186 0.010
ion transmembrane transport GO:0034220 338 0.010
cellular response to biotic stimulus GO:0071216 71 0.010
positive regulation of nucleotide catabolic process GO:0030813 185 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
negative regulation of cellular component organization GO:0051129 235 0.010
negative regulation of cell cycle GO:0045786 193 0.010
protein targeting to membrane GO:0006612 42 0.010
regulation of protein binding GO:0043393 66 0.010
signal transduction by phosphorylation GO:0023014 297 0.010
peripheral nervous system development GO:0007422 2 0.010
neuromuscular junction development GO:0007528 3 0.010
organophosphate biosynthetic process GO:0090407 163 0.010
blastoderm segmentation GO:0007350 2 0.010
nuclear transport GO:0051169 179 0.010
endomembrane system organization GO:0010256 196 0.010
leukocyte apoptotic process GO:0071887 31 0.010
regulation of kinase activity GO:0043549 314 0.010
regulation of anatomical structure morphogenesis GO:0022603 286 0.010
nervous system development GO:0007399 293 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010

DERL2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.045
inherited metabolic disorder DOID:655 242 0.039
central nervous system disease DOID:331 186 0.020
nervous system disease DOID:863 431 0.020
sensory system disease DOID:0050155 203 0.016
musculoskeletal system disease DOID:17 223 0.016
carbohydrate metabolic disorder DOID:2978 55 0.014
eye and adnexa disease DOID:1492 150 0.014
eye disease DOID:5614 149 0.014
disease of cellular proliferation DOID:14566 174 0.012
cancer DOID:162 167 0.012
organ system cancer DOID:0050686 164 0.010