|
|
phospholipid translocation
|
GO:0045332 |
2 |
0.999
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.998
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.996
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.996
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.994
|
Human Yeast Fly |
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
212 |
0.991
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.984
|
Yeast |
|
|
negative regulation of protein localization to cell surface
|
GO:2000009 |
5 |
0.983
|
Human |
|
|
early endosome to golgi transport
|
GO:0034498 |
3 |
0.983
|
|
|
|
regulation of protein oligomerization
|
GO:0032459 |
26 |
0.980
|
|
|
|
lipid translocation
|
GO:0034204 |
2 |
0.979
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.975
|
Yeast |
|
|
oxidative stress induced premature senescence
|
GO:0090403 |
3 |
0.971
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.970
|
Mouse |
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.968
|
Human |
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.965
|
|
|
|
positive regulation of protein oligomerization
|
GO:0032461 |
17 |
0.963
|
|
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.957
|
Yeast |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.949
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.947
|
|
|
|
positive regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014068 |
28 |
0.947
|
Human |
|
|
protein monoubiquitination
|
GO:0006513 |
39 |
0.943
|
Yeast |
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.943
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.942
|
Human |
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.939
|
Human |
|
|
macropinocytosis
|
GO:0044351 |
1 |
0.937
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.934
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.929
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.928
|
Human Yeast |
|
|
regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0043618 |
17 |
0.917
|
Human |
|
|
cell development
|
GO:0048468 |
328 |
0.914
|
Human Worm |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.909
|
Yeast |
|
|
regulation of dna templated transcription in response to stress
|
GO:0043620 |
18 |
0.907
|
Human |
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.893
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.892
|
|
|
|
endosome organization
|
GO:0007032 |
20 |
0.891
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.889
|
Worm |
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.885
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.883
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.873
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.868
|
Worm Fly |
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.834
|
Human |
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.834
|
Human |
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.830
|
Yeast |
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.830
|
Human Yeast Mouse |
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.825
|
Yeast |
|
|
protein localization to cell surface
|
GO:0034394 |
28 |
0.822
|
Human |
|
|
positive regulation of protein complex assembly
|
GO:0031334 |
86 |
0.817
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.817
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.807
|
|
|
|
glycerolipid metabolic process
|
GO:0046486 |
107 |
0.794
|
|
|
|
protein oligomerization
|
GO:0051259 |
173 |
0.772
|
|
|
|
anion transport
|
GO:0006820 |
161 |
0.769
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.756
|
Yeast |
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.755
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.753
|
Yeast |
|
|
regulation of phosphatidylinositol 3 kinase signaling
|
GO:0014066 |
35 |
0.749
|
Human |
|
|
negative regulation of leukocyte activation
|
GO:0002695 |
26 |
0.746
|
Mouse |
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.743
|
Yeast |
|
|
histone monoubiquitination
|
GO:0010390 |
20 |
0.738
|
|
|
|
protein polyubiquitination
|
GO:0000209 |
110 |
0.731
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.729
|
|
|
|
regulation of epithelial cell migration
|
GO:0010632 |
93 |
0.727
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.719
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.718
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.716
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.711
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.706
|
Yeast |
|
|
negative regulation of sodium ion transmembrane transport
|
GO:1902306 |
2 |
0.702
|
Human |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.701
|
Human Worm |
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.698
|
Yeast |
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.694
|
Human |
|
|
negative regulation of cellular response to growth factor stimulus
|
GO:0090288 |
41 |
0.687
|
Human |
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.684
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.677
|
Human |
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.671
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.663
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.658
|
|
|
|
positive regulation of protein localization to cell surface
|
GO:2000010 |
6 |
0.657
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.656
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.652
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.648
|
Human |
|
|
nervous system development
|
GO:0007399 |
293 |
0.647
|
Human Worm |
|
|
dna repair
|
GO:0006281 |
198 |
0.641
|
|
|
|
protein k48 linked ubiquitination
|
GO:0070936 |
38 |
0.628
|
|
|
|
cofactor metabolic process
|
GO:0051186 |
87 |
0.626
|
Yeast |
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.611
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.602
|
Fly |
|
|
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090101 |
45 |
0.601
|
Human |
|
|
phosphatidylinositol 3 kinase signaling
|
GO:0014065 |
48 |
0.599
|
Human |
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.597
|
Human |
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.597
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.597
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.595
|
Human Worm |
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.592
|
Mouse |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.590
|
Human Yeast Fly |
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.588
|
Human Yeast Mouse |
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.585
|
Human Yeast Mouse Worm |
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.581
|
|
|
|
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway
|
GO:0035625 |
4 |
0.581
|
|
|
|
negative regulation of jun kinase activity
|
GO:0043508 |
4 |
0.578
|
|
|
|
regulation of receptor mediated endocytosis
|
GO:0048259 |
32 |
0.570
|
Yeast |
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.566
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.561
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.559
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.554
|
|
|
|
negative regulation of ion transport
|
GO:0043271 |
39 |
0.544
|
Human |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.544
|
Mouse |
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.534
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.529
|
Yeast |
|
|
coenzyme metabolic process
|
GO:0006732 |
65 |
0.527
|
Yeast |
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.526
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.518
|
|
|
|
regulation of response to osmotic stress
|
GO:0047484 |
3 |
0.512
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.506
|
Human |
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.499
|
Yeast |
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.497
|
Human |
|
|
positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
|
GO:1902255 |
2 |
0.485
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.472
|
|
|
|
cell aging
|
GO:0007569 |
52 |
0.469
|
|
|
|
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001240 |
16 |
0.467
|
|
|
|
negative regulation of map kinase activity
|
GO:0043407 |
27 |
0.463
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.460
|
Yeast |
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.458
|
|
|
|
polyprenol biosynthetic process
|
GO:0016094 |
1 |
0.457
|
Yeast |
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.457
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.454
|
Yeast |
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.453
|
Mouse |
|
|
receptor internalization
|
GO:0031623 |
43 |
0.452
|
Human Fly |
|
|
membrane protein proteolysis
|
GO:0033619 |
38 |
0.446
|
|
|
|
regulation of endocytosis
|
GO:0030100 |
72 |
0.432
|
Yeast |
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.428
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.425
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.420
|
|
|
|
regulation of extrinsic apoptotic signaling pathway
|
GO:2001236 |
85 |
0.416
|
|
|
|
phosphatidylinositol mediated signaling
|
GO:0048015 |
55 |
0.414
|
Human |
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
71 |
0.412
|
Yeast |
|
|
positive regulation of osteoblast differentiation
|
GO:0045669 |
23 |
0.407
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.407
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.405
|
|
|
|
membrane tubulation
|
GO:0097320 |
12 |
0.403
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.401
|
Yeast |
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.400
|
Mouse |
|
|
regulation of endosome size
|
GO:0051036 |
3 |
0.396
|
Yeast |
|
|
negative regulation of sodium ion transport
|
GO:0010766 |
3 |
0.390
|
Human |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.387
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.381
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.379
|
|
|
|
regulation of mrna export from nucleus
|
GO:0010793 |
3 |
0.378
|
Yeast |
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.378
|
|
|
|
ubiquitin dependent endocytosis
|
GO:0070086 |
1 |
0.376
|
Yeast |
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.374
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.371
|
|
|
|
sphingolipid metabolic process
|
GO:0006665 |
38 |
0.367
|
|
|
|
regulation of membrane lipid distribution
|
GO:0097035 |
9 |
0.367
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.361
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.357
|
Human Yeast |
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.356
|
Yeast |
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.354
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.352
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.351
|
Yeast |
|
|
carboxylic acid biosynthetic process
|
GO:0046394 |
97 |
0.343
|
Yeast |
|
|
cytoskeleton dependent cytokinesis
|
GO:0061640 |
22 |
0.339
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.338
|
Worm |
|
|
cellular response to radiation
|
GO:0071478 |
65 |
0.337
|
Human Yeast |
|
|
organic anion transport
|
GO:0015711 |
103 |
0.336
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.333
|
|
|
|
fatty acid biosynthetic process
|
GO:0006633 |
46 |
0.333
|
Yeast |
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.333
|
Human Yeast |
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.330
|
Yeast |
|
|
dissemination or transmission of symbiont from host
|
GO:0044007 |
1 |
0.328
|
Human |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.327
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.324
|
Mouse |
|
|
regulation of protein localization to cell surface
|
GO:2000008 |
15 |
0.322
|
Human |
|
|
membrane organization
|
GO:0061024 |
292 |
0.320
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.318
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.317
|
|
|
|
coenzyme biosynthetic process
|
GO:0009108 |
24 |
0.316
|
Yeast |
|
|
ncrna metabolic process
|
GO:0034660 |
108 |
0.312
|
Yeast |
|
|
ribosomal large subunit export from nucleus
|
GO:0000055 |
3 |
0.311
|
Yeast |
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.310
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.309
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.309
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.309
|
Yeast |
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.300
|
Mouse |
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.296
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.289
|
|
|
|
peptidyl tyrosine modification
|
GO:0018212 |
170 |
0.286
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.285
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.281
|
Human Yeast |
|
|
regulation of intrinsic apoptotic signaling pathway
|
GO:2001242 |
72 |
0.279
|
|
|
|
organelle localization
|
GO:0051640 |
84 |
0.277
|
Yeast |
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.277
|
|
|
|
regulation of notch signaling pathway
|
GO:0008593 |
18 |
0.276
|
Fly |
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.276
|
|
|
|
rrna containing ribonucleoprotein complex export from nucleus
|
GO:0071428 |
4 |
0.276
|
Yeast |
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.274
|
|
|
|
regulation of t cell activation
|
GO:0050863 |
77 |
0.274
|
Mouse |
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.268
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.267
|
Human |
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.266
|
|
|
|
growth
|
GO:0040007 |
202 |
0.265
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.258
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.253
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.252
|
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
156 |
0.248
|
Human Yeast |
|
|
endocytosis
|
GO:0006897 |
159 |
0.247
|
Human Yeast Fly |
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.244
|
Mouse |
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.242
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.240
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.239
|
|
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.239
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.237
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.236
|
|
|
|
negative regulation of lipid transport
|
GO:0032369 |
18 |
0.229
|
|
|
|
eye photoreceptor cell differentiation
|
GO:0001754 |
2 |
0.229
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.225
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.224
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.223
|
|
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.222
|
|
|
|
small molecule biosynthetic process
|
GO:0044283 |
157 |
0.222
|
Yeast |
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.221
|
Yeast |
|
|
regulation of lipid biosynthetic process
|
GO:0046890 |
47 |
0.220
|
Yeast |
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.219
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.219
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.219
|
Human Yeast |
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.218
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.218
|
Human |
|
|
epithelium migration
|
GO:0090132 |
119 |
0.217
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.217
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.216
|
Mouse |
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.215
|
|
|
|
regulation of protein tyrosine kinase activity
|
GO:0061097 |
36 |
0.215
|
|
|
|
golgi vesicle transport
|
GO:0048193 |
80 |
0.215
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.211
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.211
|
|
|
|
lipid tube assembly
|
GO:0060988 |
2 |
0.211
|
|
|
|
protein lipid complex assembly
|
GO:0065005 |
12 |
0.209
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.208
|
|
|
|
negative regulation of neuron differentiation
|
GO:0045665 |
21 |
0.206
|
|
|
|
cleavage furrow formation
|
GO:0036089 |
5 |
0.206
|
|
|
|
development involved in symbiotic interaction
|
GO:0044111 |
1 |
0.205
|
Human |
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.204
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.204
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.203
|
|
|
|
membrane protein ectodomain proteolysis
|
GO:0006509 |
33 |
0.202
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.200
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.198
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.198
|
Mouse |
|
|
negative regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010768 |
1 |
0.198
|
Human |
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.195
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.194
|
|
|
|
positive regulation of apoptotic signaling pathway
|
GO:2001235 |
70 |
0.193
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.191
|
Yeast |
|
|
mitotic cytokinesis
|
GO:0000281 |
19 |
0.190
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.189
|
|
|
|
muscle cell proliferation
|
GO:0033002 |
35 |
0.188
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.188
|
|
|
|
positive regulation of mitochondrion organization
|
GO:0010822 |
30 |
0.187
|
|
|
|
defense response to bacterium
|
GO:0042742 |
63 |
0.187
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.187
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.187
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.187
|
|
|
|
negative regulation of cardiac muscle cell proliferation
|
GO:0060044 |
2 |
0.185
|
|
|
|
negative regulation of phospholipid transport
|
GO:2001139 |
1 |
0.185
|
|
|
|
trna transport
|
GO:0051031 |
1 |
0.184
|
Yeast |
|
|
membrane lipid metabolic process
|
GO:0006643 |
53 |
0.183
|
|
|
|
activation of mapk activity
|
GO:0000187 |
45 |
0.180
|
|
|
|
regulation of potassium ion transport
|
GO:0043266 |
24 |
0.179
|
Human |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.179
|
|
|
|
negative regulation of lipid biosynthetic process
|
GO:0051055 |
22 |
0.177
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.177
|
Mouse |
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.176
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.175
|
Human Yeast |
|
|
establishment of organelle localization
|
GO:0051656 |
59 |
0.173
|
Yeast |
|
|
oxidoreduction coenzyme metabolic process
|
GO:0006733 |
19 |
0.172
|
Yeast |
|
|
cell activation
|
GO:0001775 |
213 |
0.171
|
Mouse |
|
|
dolichol biosynthetic process
|
GO:0019408 |
1 |
0.171
|
Yeast |
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.168
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.167
|
Yeast |
|
|
transcription from rna polymerase iii promoter
|
GO:0006383 |
19 |
0.163
|
|
|
|
late endosome to vacuole transport
|
GO:0045324 |
2 |
0.163
|
Yeast |
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.162
|
|
|
|
regulation of cell activation
|
GO:0050865 |
125 |
0.161
|
Mouse |
|
|
secretion
|
GO:0046903 |
254 |
0.160
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.160
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.160
|
Human |
|
|
synaptic vesicle endocytosis
|
GO:0048488 |
2 |
0.159
|
|
|
|
phospholipid transport
|
GO:0015914 |
23 |
0.158
|
|
|
|
regulation of ribosome biogenesis
|
GO:0090069 |
1 |
0.158
|
Yeast |
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.157
|
|
|
|
positive regulation of membrane protein ectodomain proteolysis
|
GO:0051044 |
13 |
0.157
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.157
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.156
|
|
|
|
maintenance of cell polarity
|
GO:0030011 |
2 |
0.155
|
|
|
|
hepatocyte growth factor receptor signaling pathway
|
GO:0048012 |
8 |
0.154
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.153
|
Human Yeast |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.151
|
Human |
|
|
positive regulation of fibroblast apoptotic process
|
GO:2000271 |
6 |
0.151
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.147
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.145
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.144
|
|
|
|
regulation of protein ubiquitination
|
GO:0031396 |
95 |
0.143
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.142
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.142
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.141
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.139
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.136
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.135
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.135
|
Worm Fly |
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.134
|
|
|
|
regionalization
|
GO:0003002 |
29 |
0.134
|
Fly |
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.133
|
Mouse |
|
|
positive regulation of endothelial cell migration
|
GO:0010595 |
39 |
0.133
|
|
|
|
protein ubiquitination involved in ubiquitin dependent protein catabolic process
|
GO:0042787 |
37 |
0.130
|
Human Yeast Mouse |
|
|
trna processing
|
GO:0008033 |
23 |
0.128
|
Yeast |
|
|
cellular response to nutrient levels
|
GO:0031669 |
69 |
0.127
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.127
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.127
|
Yeast |
|
|
regulation of transcription from rna polymerase iii promoter
|
GO:0006359 |
13 |
0.126
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.125
|
Mouse |
|
|
muscle structure development
|
GO:0061061 |
98 |
0.123
|
|
|
|
regulation of extrinsic apoptotic signaling pathway in absence of ligand
|
GO:2001239 |
20 |
0.121
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.120
|
Human Yeast |
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.120
|
Yeast |
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.120
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.119
|
|
|
|
quinone metabolic process
|
GO:1901661 |
18 |
0.118
|
Yeast |
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.118
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.118
|
Human |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.117
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.116
|
Human Worm |
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.115
|
|
|
|
notch signaling pathway
|
GO:0007219 |
31 |
0.115
|
Fly |
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.114
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.112
|
Human |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.112
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.111
|
Human |
|
|
regulation of ketone biosynthetic process
|
GO:0010566 |
7 |
0.111
|
Yeast |
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.110
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.110
|
Human |
|
|
isoprenoid metabolic process
|
GO:0006720 |
39 |
0.109
|
Yeast |
|
|
protein k63 linked ubiquitination
|
GO:0070534 |
31 |
0.107
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.107
|
|
|
|
membrane lipid biosynthetic process
|
GO:0046467 |
27 |
0.107
|
|
|
|
dna damage response signal transduction by p53 class mediator
|
GO:0030330 |
44 |
0.107
|
|
|
|
response to ionizing radiation
|
GO:0010212 |
65 |
0.106
|
|
|
|
trna export from nucleus
|
GO:0006409 |
1 |
0.106
|
Yeast |
|
|
signal transduction in response to dna damage
|
GO:0042770 |
57 |
0.105
|
|
|
|
pattern specification process
|
GO:0007389 |
43 |
0.104
|
Fly |
|
|
biological adhesion
|
GO:0022610 |
331 |
0.104
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.103
|
|
|
|
ubiquitin dependent smad protein catabolic process
|
GO:0030579 |
4 |
0.102
|
Human |
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.101
|
|
|
|
receptor mediated endocytosis
|
GO:0006898 |
84 |
0.099
|
Human Yeast Fly |
|
|
chronological cell aging
|
GO:0001300 |
2 |
0.099
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.099
|
|
|
|
establishment of ribosome localization
|
GO:0033753 |
4 |
0.098
|
Yeast |
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.097
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.096
|
|
|
|
regulation of cardiac muscle cell proliferation
|
GO:0060043 |
4 |
0.095
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.094
|
|
|
|
negative regulation of endocytosis
|
GO:0045806 |
19 |
0.094
|
|
|
|
cell chemotaxis
|
GO:0060326 |
112 |
0.094
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.094
|
Mouse |
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.093
|
|
|
|
pinocytosis
|
GO:0006907 |
8 |
0.091
|
|
|
|
glial cell differentiation
|
GO:0010001 |
11 |
0.091
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.091
|
|
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.091
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.090
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.090
|
|
|
|
regulation of rrna processing
|
GO:2000232 |
1 |
0.089
|
Yeast |
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.088
|
|
|
|
negative regulation of apoptotic signaling pathway
|
GO:2001234 |
97 |
0.088
|
|
|
|
regulation of cardiac muscle tissue growth
|
GO:0055021 |
4 |
0.087
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.087
|
|
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.086
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.086
|
Human |
|
|
histone ubiquitination
|
GO:0016574 |
31 |
0.085
|
|
|
|
regulation of osteoblast differentiation
|
GO:0045667 |
38 |
0.085
|
|
|
|
negative regulation of protein transport
|
GO:0051224 |
75 |
0.084
|
Human |
|
|
negative regulation of hormone metabolic process
|
GO:0032351 |
6 |
0.084
|
|
|
|
negative regulation of lymphocyte differentiation
|
GO:0045620 |
7 |
0.083
|
|
|
|
regulation of cellular response to growth factor stimulus
|
GO:0090287 |
76 |
0.083
|
Human |
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.082
|
|
|
|
regulation of lipid metabolic process
|
GO:0019216 |
96 |
0.082
|
Yeast |
|
|
response to bacterium
|
GO:0009617 |
144 |
0.081
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.080
|
|
|
|
negative regulation of leukocyte differentiation
|
GO:1902106 |
24 |
0.079
|
|
|
|
endosome transport via multivesicular body sorting pathway
|
GO:0032509 |
3 |
0.078
|
Yeast |
|
|
cellular response to decreased oxygen levels
|
GO:0036294 |
51 |
0.078
|
|
|
|
lipid transport
|
GO:0006869 |
90 |
0.078
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.078
|
|
|
|
regulation of endothelial cell migration
|
GO:0010594 |
67 |
0.078
|
|
|
|
negative regulation of t cell activation
|
GO:0050868 |
18 |
0.077
|
Mouse |
|
|
autophagy
|
GO:0006914 |
88 |
0.077
|
Yeast |
|
|
receptor transactivation
|
GO:0035624 |
4 |
0.077
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.076
|
|
|
|
regulation of mitochondrion organization
|
GO:0010821 |
54 |
0.076
|
|
|
|
cofactor biosynthetic process
|
GO:0051188 |
31 |
0.076
|
Yeast |
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.075
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.075
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.074
|
Human Worm |
|
|
positive regulation of epithelial cell migration
|
GO:0010634 |
55 |
0.074
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.074
|
Human |
|
|
positive regulation of neurogenesis
|
GO:0050769 |
49 |
0.073
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.073
|
|
|
|
negative regulation of epidermal growth factor activated receptor activity
|
GO:0007175 |
6 |
0.073
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.072
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.071
|
Mouse |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.071
|
|
|
|
striated muscle cell proliferation
|
GO:0014855 |
7 |
0.070
|
|
|
|
regulation of epidermal growth factor activated receptor activity
|
GO:0007176 |
14 |
0.070
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.070
|
Human Fly |
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.069
|
|
|
|
regulation of isoprenoid metabolic process
|
GO:0019747 |
1 |
0.069
|
Yeast |
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.069
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.069
|
|
|
|
cellular response to fibroblast growth factor stimulus
|
GO:0044344 |
39 |
0.068
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.067
|
|
|
|
regulation of sphingolipid biosynthetic process
|
GO:0090153 |
2 |
0.066
|
|
|
|
regulation of hormone metabolic process
|
GO:0032350 |
14 |
0.066
|
|
|
|
negative regulation of striated muscle tissue development
|
GO:0045843 |
11 |
0.066
|
|
|
|
fibroblast apoptotic process
|
GO:0044346 |
8 |
0.066
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.065
|
|
|
|
ribonucleoprotein complex localization
|
GO:0071166 |
4 |
0.065
|
Yeast |
|
|
secretion by cell
|
GO:0032940 |
226 |
0.065
|
|
|
|
regulation of transcription from rna polymerase ii promoter in response to uv induced dna damage
|
GO:0010767 |
1 |
0.065
|
Human |
|
|
positive regulation of phospholipid transport
|
GO:2001140 |
4 |
0.064
|
|
|
|
ribosomal subunit export from nucleus
|
GO:0000054 |
4 |
0.064
|
Yeast |
|
|
immune system development
|
GO:0002520 |
195 |
0.064
|
Mouse |
|
|
cellular response to biotic stimulus
|
GO:0071216 |
71 |
0.064
|
|
|
|
regulation of cofactor metabolic process
|
GO:0051193 |
3 |
0.063
|
Yeast |
|
|
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway
|
GO:0043162 |
10 |
0.063
|
Human Yeast |
|
|
nitrogen compound transport
|
GO:0071705 |
191 |
0.063
|
Yeast |
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.062
|
Fly |
|
|
immune response regulating cell surface receptor signaling pathway
|
GO:0002768 |
51 |
0.062
|
|
|
|
nucleotide excision repair
|
GO:0006289 |
31 |
0.062
|
|
|
|
hormone biosynthetic process
|
GO:0042446 |
22 |
0.062
|
|
|
|
regulation of microtubule cytoskeleton organization
|
GO:0070507 |
61 |
0.061
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.061
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.061
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.061
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.061
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.061
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.061
|
|
|
|
negative regulation of mapk cascade
|
GO:0043409 |
56 |
0.060
|
Mouse |
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.060
|
Yeast |
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.060
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.060
|
|
|
|
notch receptor processing
|
GO:0007220 |
2 |
0.059
|
|
|
|
organic hydroxy compound metabolic process
|
GO:1901615 |
147 |
0.059
|
Yeast |
|
|
ncrna processing
|
GO:0034470 |
83 |
0.059
|
Yeast |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.059
|
Human Yeast Worm |
|
|
response to cytokine
|
GO:0034097 |
232 |
0.058
|
|
|
|
ribosome localization
|
GO:0033750 |
4 |
0.058
|
Yeast |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.057
|
|
|
|
regulation of hormone biosynthetic process
|
GO:0046885 |
10 |
0.057
|
|
|
|
negative regulation of stress activated mapk cascade
|
GO:0032873 |
19 |
0.057
|
Mouse |
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.056
|
Mouse |
|
|
positive regulation of endocytosis
|
GO:0045807 |
42 |
0.056
|
Yeast |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.056
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.055
|
|
|
|
polyprenol metabolic process
|
GO:0016093 |
3 |
0.054
|
Yeast |
|
|
regulation of potassium ion transmembrane transport
|
GO:1901379 |
20 |
0.054
|
Human |
|
|
transmission of virus
|
GO:0019089 |
1 |
0.054
|
Human |
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.053
|
|
|
|
signal transduction in absence of ligand
|
GO:0038034 |
22 |
0.053
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.053
|
|
|
|
negative regulation of peptidyl tyrosine phosphorylation
|
GO:0050732 |
20 |
0.053
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.053
|
|
|
|
response to drug
|
GO:0042493 |
81 |
0.052
|
Yeast |
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.051
|
|
|
|
regulation of erbb signaling pathway
|
GO:1901184 |
27 |
0.051
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.051
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.051
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.051
|
|
|
|
negative regulation of lipid metabolic process
|
GO:0045833 |
38 |
0.050
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.050
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.050
|
Yeast |
|
|
cellular response to oxygen levels
|
GO:0071453 |
55 |
0.050
|
|
|
|
regulation of coenzyme metabolic process
|
GO:0051196 |
3 |
0.050
|
Yeast |
|
|
response to uv
|
GO:0009411 |
73 |
0.049
|
Human Yeast |
|
|
immune response activating cell surface receptor signaling pathway
|
GO:0002429 |
45 |
0.049
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.049
|
|
